Diazaborine treatment of yeast cells inhibits maturation of the 60S ribosomal subunit

scientific article

Diazaborine treatment of yeast cells inhibits maturation of the 60S ribosomal subunit is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.24.14.6476-6487.2004
P3181OpenCitations bibliographic resource ID4348161
P932PMC publication ID434233
P698PubMed publication ID15226447

P50authorRené KöffelQ38318041
Helmut BerglerQ59659809
Brigitte PertschyQ28833255
Karlheinz GrillitschQ30171861
P2093author name stringGertrude Zisser
Christina Morgenstern
Gernot Rauch
Gregor Högenauer
Hermine Schein
Michael Durchschlag
P2860cites work90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factorsQ24302526
The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanismQ24322559
The final step in the formation of 25S rRNA in Saccharomyces cerevisiae is performed by 5'-->3' exonucleasesQ24539838
The 5' end of yeast 5.8S rRNA is generated by exonucleases from an upstream cleavage siteQ24595513
Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRPQ24601905
Rpp2, an essential protein subunit of nuclear RNase P, is required for processing of precursor tRNAs and 35S precursor rRNA in Saccharomyces cerevisiaeQ24657647
Sequential protein association with nascent 60S ribosomal particlesQ24683118
Dbp9p, a putative ATP-dependent RNA helicase involved in 60S-ribosomal-subunit biogenesis, functionally interacts with Dbp6pQ27930128
Making ribosomesQ27930690
Imp3p and Imp4p, two specific components of the U3 small nucleolar ribonucleoprotein that are essential for pre-18S rRNA processingQ27930834
AAA proteinsQ35035247
Chemogenomic profiling: identifying the functional interactions of small molecules in yeastQ35554300
A temperature sensitive mutant of Saccharomyces cerevisiae defective in pre-rRNA processingQ35782598
Fragments of the internal transcribed spacer 1 of pre-rRNA accumulate in Saccharomyces cerevisiae lacking 5'----3' exoribonuclease 1Q36164476
envM genes of Salmonella typhimurium and Escherichia coliQ39951118
AFG2, an essential gene in yeast, encodes a new member of the Sec18p, Pas1p, Cdc48p, TBP-1 family of putative ATPasesQ42602082
Yeast Rnt1p is required for cleavage of the pre-ribosomal RNA in the 3' ETS but not the 5' ETS.Q43206467
The Cytoplasmic Maturation of a Ribosomal Precursor Ribonucleic Acid in YeastQ54151635
Protein EnvM is the NADH-dependent enoyl-ACP reductase (FabI) of Escherichia coli.Q54639813
Diazaborine treatment of Baker's yeast results in stabilization of aberrant mRNAsQ74285043
Structural and enzymatic properties of the AAA protein Drg1p from Saccharomyces cerevisiae. Decoupling of intracellular function from ATPase activity and hexamerization.Q27932034
The yeast nucleolar protein Nop4p contains four RNA recognition motifs necessary for ribosome biogenesis.Q27933377
Saccharomyces cerevisiae nucleolar protein Nop7p is necessary for biogenesis of 60S ribosomal subunits.Q27933982
Identification of a 60S preribosomal particle that is closely linked to nuclear export.Q27934965
Ssf1p prevents premature processing of an early pre-60S ribosomal particleQ27935091
Ribosome synthesis in Saccharomyces cerevisiaeQ27935371
The path from nucleolar 90S to cytoplasmic 40S pre-ribosomesQ27935442
Diazaborine resistance in yeast involves the efflux pumps Ycf1p and Flr1p and is enhanced by a gain-of-function allele of gene YAP1.Q27935507
A novel protein shared by RNase MRP and RNase P.Q27935679
DRS1 to DRS7, novel genes required for ribosome assembly and function in Saccharomyces cerevisiaeQ27935888
60S pre-ribosome formation viewed from assembly in the nucleolus until export to the cytoplasmQ27936133
Composition and functional characterization of yeast 66S ribosome assembly intermediates.Q27936383
The POP1 gene encodes a protein component common to the RNase MRP and RNase P ribonucleoproteinsQ27936503
Mutagenesis of SNM1, which encodes a protein component of the yeast RNase MRP, reveals a role for this ribonucleoprotein endoribonuclease in plasmid segregationQ27936937
Maturation and intranuclear transport of pre-ribosomes requires Noc proteinsQ27937254
Nuclear export of 60s ribosomal subunits depends on Xpo1p and requires a nuclear export sequence-containing factor, Nmd3p, that associates with the large subunit protein Rpl10pQ27937695
Pop3p is essential for the activity of the RNase MRP and RNase P ribonucleoproteins in vivoQ27937799
Diazaborine resistance in the yeast Saccharomyces cerevisiae reveals a link between YAP1 and the pleiotropic drug resistance genes PDR1 and PDR3.Q27938341
The yeast NOP4 gene product is an essential nucleolar protein required for pre-rRNA processing and accumulation of 60S ribosomal subunits.Q27938519
Rpp1, an essential protein subunit of nuclear RNase P required for processing of precursor tRNA and 35S precursor rRNA in Saccharomyces cerevisiae.Q27938731
Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3' end formation of 5.8S rRNA in Saccharomyces cerevisiaeQ27939006
Nmd3p is a Crm1p-dependent adapter protein for nuclear export of the large ribosomal subunitQ27939125
Processing of the precursors to small nucleolar RNAs and rRNAs requires common componentsQ27940213
Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotesQ28238338
Pre-ribosomes on the road from the nucleolus to the cytoplasmQ29616319
Nuclear RNase MRP is required for correct processing of pre-5.8S rRNA in Saccharomyces cerevisiaeQ29620104
Accurate processing of a eukaryotic precursor ribosomal RNA by ribonuclease MRP in vitroQ29620282
Depletion of U3 small nucleolar RNA inhibits cleavage in the 5′ external transcribed spacer of yeast pre-ribosomal RNA and impairs formation of 18S ribosomal RNAQ29620875
Synthetic lethality with fibrillarin identifies NOP77p, a nucleolar protein required for pre-rRNA processing and modificationQ29622954
Role of the ITS2-proximal stem and evidence for indirect recognition of processing sites in pre-rRNA processing in yeastQ33932018
The RNA of RNase MRP is required for normal processing of ribosomal RNA.Q34991585
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
ATP-dependent RNA helicase MTR4 YJL050WQ27548544
P304page(s)6476-87
P577publication date2004-07-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleDiazaborine treatment of yeast cells inhibits maturation of the 60S ribosomal subunit
P478volume24

Reverse relations

cites work (P2860)
Q40092854A pharmaco-epistasis strategy reveals a new cell size controlling pathway in yeast.
Q57976127Boron-Nitrogen Bond
Q35843523Chemical modulators of ribosome biogenesis as biological probes
Q27933234Cytoplasmic recycling of 60S preribosomal factors depends on the AAA protein Drg1.
Q37371673Diversity in enoyl-acyl carrier protein reductases
Q64990556Inhibiting eukaryotic ribosome biogenesis.
Q64120358Proteotoxicity from aberrant ribosome biogenesis compromises cell fitness
Q41954752The drug diazaborine blocks ribosome biogenesis by inhibiting the AAA-ATPase Drg1.
Q35690797The power of AAA-ATPases on the road of pre-60S ribosome maturation--molecular machines that strip pre-ribosomal particles
Q28080940Using modern tools to probe the structure-function relationship of fatty acid synthases
Q47238106Viewing pre-60S maturation at a minute's timescale.
Q27935709Yeast Uri1p promotes translation initiation and may provide a link to cotranslational quality control.
Q37359194Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.
Q27322883YphC and YsxC GTPases assist the maturation of the central protuberance, GTPase associated region and functional core of the 50S ribosomal subunit

Search more.