| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Rafael de Cabo | |
| Robin K Minor | |||
| Theresa M Ward | |||
| Joanne S Allard | |||
| Caitlin M Younts | |||
| P2860 | cites work | A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice | Q21092211 |
| Dietary antioxidants and primary prevention of age related macular degeneration: systematic review and meta-analysis | Q24569500 | ||
| Acute antihyperglycemic mechanisms of metformin in NIDDM. Evidence for suppression of lipid oxidation and hepatic glucose production | Q72020678 | ||
| Weight cycling. National Task Force on the Prevention and Treatment of Obesity | Q72217647 | ||
| Longevity and protein intake | Q72326855 | ||
| In vivo 2-deoxyglucose administration preserves glucose and glutamate transport and mitochondrial function in cortical synaptic terminals after exposure to amyloid beta-peptide and iron: evidence for a stress response | Q73076394 | ||
| Pyridoxamine, an inhibitor of advanced glycation reactions, also inhibits advanced lipoxidation reactions. Mechanism of action of pyridoxamine | Q73763318 | ||
| Program for testing biological interventions to promote healthy aging | Q74038421 | ||
| Utility of metformin as an adjunct to hydroxycitrate/carnitine for reducing body fat in diabetics | Q77664879 | ||
| Prevention of mammary tumorigenesis by intermittent caloric restriction: does caloric intake during refeeding modulate the response? | Q79486080 | ||
| Structural and functional changes of immune system in aging mouse induced by D-galactose | Q79823939 | ||
| Collagen glycation triggers the formation of aged skin in vitro | Q79836694 | ||
| Can dietary restriction increase longevity in all species, particularly in human beings? Introduction to a debate among experts | Q83865386 | ||
| Methionine restriction decreases mitochondrial oxygen radical generation and leak as well as oxidative damage to mitochondrial DNA and proteins | Q83978389 | ||
| Mouse neoplasia and immunity: effects of radiation, hyperthermia, 2-deoxy-D-glucose, and Corynebacterium parvum | Q93651353 | ||
| SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1 | Q24633063 | ||
| Chronic ingestion of 2-deoxy-D-glucose induces cardiac vacuolization and increases mortality in rats | Q24634601 | ||
| Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway | Q24643816 | ||
| Targeting the mammalian target of rapamycin (mTOR): a new approach to treating cancer | Q24645461 | ||
| Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes | Q24645537 | ||
| Rapamycin fed late in life extends lifespan in genetically heterogeneous mice | Q24647805 | ||
| Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span | Q24649811 | ||
| Caloric restriction delays disease onset and mortality in rhesus monkeys | Q24655994 | ||
| Aging: a theory based on free radical and radiation chemistry | Q27860549 | ||
| TOR signaling in growth and metabolism | Q27860757 | ||
| Resveratrol improves health and survival of mice on a high-calorie diet | Q27860950 | ||
| Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae | Q27931494 | ||
| Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans | Q28131824 | ||
| Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan | Q28203572 | ||
| An Aging Interventions Testing Program: study design and interim report | Q28213590 | ||
| Position statement on human aging | Q28216232 | ||
| Position of the American Dietetic Association: vegetarian diets | Q28250235 | ||
| Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress | Q28251449 | ||
| SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B | Q28251461 | ||
| The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span | Q28272121 | ||
| Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha | Q28274682 | ||
| Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients | Q28282424 | ||
| Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis | Q28290519 | ||
| Sirtuin activators mimic caloric restriction and delay ageing in metazoans | Q29547766 | ||
| Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration | Q29618751 | ||
| The effect of retarded growth upon the length of life span and upon the ultimate body size. 1935 | Q29620325 | ||
| It's never too late: calorie restriction is effective in older mammals | Q30088175 | ||
| Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy | Q30312025 | ||
| Therapeutic potential of resveratrol in Alzheimer's disease | Q30855117 | ||
| Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo | Q33417863 | ||
| Serum amine oxidase activity contributes to crisis in mouse embryo cell lines | Q33619232 | ||
| Inhibition of mammary tumor growth and metastases to bone and liver by dietary grape polyphenols | Q33967930 | ||
| Consuming a diet supplemented with resveratrol reduced infection-related neuroinflammation and deficits in working memory in aged mice | Q33991493 | ||
| Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate. | Q33993373 | ||
| Effect of intermittent fasting and refeeding on insulin action in healthy men. | Q46624613 | ||
| 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro | Q46630183 | ||
| Forty percent and eighty percent methionine restriction decrease mitochondrial ROS generation and oxidative stress in rat liver. | Q46746325 | ||
| Polyphenolic compounds from red grapes acutely improve endothelial function in patients with coronary heart disease | Q46829032 | ||
| Aminoguanidine delays the replicative senescence of human diploid fibroblasts. | Q46859641 | ||
| Does diet or alcohol explain the French paradox? | Q46934927 | ||
| Risk of mortality and adverse cardiovascular outcomes in type 2 diabetes: a comparison of patients treated with sulfonylureas and metformin | Q46981921 | ||
| The effect of short periods of caloric restriction on weight loss and glycemic control in type 2 diabetes | Q47292095 | ||
| Body Weight Increment and Length of Life: The Effect of Genetic Constitution and Dietary Protein | Q47321250 | ||
| The Journal of Nutrition. Volume 18 July--December, 1939. Pages 1--13. Retarded growth, life span, ultimate body size and age changes in the albino rat after feeding diets restricted in calories | Q47347823 | ||
| B vitamin status and concentrations of homocysteine and methylmalonic acid in elderly German women | Q47590898 | ||
| Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: evidence for a preconditioning mechanism | Q48124285 | ||
| Characterization of the 2-deoxyglucose effect on the adrenocortical axis | Q48145080 | ||
| Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease | Q48169104 | ||
| Patho-physiologic findings after chronic tryptophan deficiency in rats: a model for delayed growth and aging | Q48400604 | ||
| Low tryptophan diets delay reproductive aging. | Q48717439 | ||
| Effects of inhibition of nitric oxide synthase by aminoguanidine in acute endotoxemia. | Q50135560 | ||
| The impact of metformin therapy on hepatic glucose production and skeletal muscle glycogen synthase activity in overweight type II diabetic patients. | Q51599034 | ||
| Restriction of amino acids extends lifespan in Drosophila melanogaster. | Q51729086 | ||
| Intermittent calorie restriction delays prostate tumor detection and increases survival time in TRAMP mice. | Q51806440 | ||
| PROFESSOR DR CHEM. BAREND COENRAAD PETRUS JANSEN (1 APRIL 1884-18 OCTOBER 1962). | Q52480374 | ||
| Food restriction prevents advanced glycation end product accumulation and retards kidney aging in lean rats. | Q52890623 | ||
| Influence of protein under- and overnutrition on spontaneous tumor prevalence in the rat. | Q54350581 | ||
| Nutritional influences on aging of Fischer 344 rats: I. Physical, metabolic, and longevity characteristics. | Q54593654 | ||
| Weight Cycling | Q56474378 | ||
| Influence of low tryptophan diet on survival and organ growth in mice | Q69669256 | ||
| Lifetime brain serotonin: regional effects of age and precursor availability | Q70720496 | ||
| Differential effects of dietary caloric and protein restriction in the aging rat | Q71205898 | ||
| Variations in nutritional status of elderly men and women according to place of residence | Q39651520 | ||
| Alcohol intake and risk of dementia | Q39680954 | ||
| Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice. | Q39805050 | ||
| Caffeine extends yeast lifespan by targeting TORC1. | Q39848096 | ||
| Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells | Q40050621 | ||
| Nonenzymatic glycosylation and the pathogenesis of diabetic complications | Q40186568 | ||
| Aminoguanidine supplementation delays the onset of senescence in vitro in dermal fibroblast-like cells from senescence-accelerated mice | Q40933376 | ||
| Methionine restriction decreases visceral fat mass and preserves insulin action in aging male Fischer 344 rats independent of energy restriction | Q42497425 | ||
| Molecular medicine in ophthalmic care | Q43237077 | ||
| The Glycosylation of Hemoglobin: Relevance to Diabetes Mellitus | Q43926917 | ||
| Amount and type of alcohol and risk of dementia: the Copenhagen City Heart Study | Q44038386 | ||
| Decreased mortality associated with the use of metformin compared with sulfonylurea monotherapy in type 2 diabetes | Q44231053 | ||
| Nutritional control of aging | Q44288340 | ||
| Intermittent fasting and dietary supplementation with 2‐deoxy‐D‐glucose improve functional and metabolic cardiovascular risk factors in rats | Q44412850 | ||
| Tissue glutathione and cysteine levels in methionine-restricted rats | Q44422059 | ||
| Dietary Protein, Life-span, and Physiological Variables in Female Mice | Q44529337 | ||
| Insulin and longevity: antidiabetic biguanides as geroprotectors | Q44656076 | ||
| Relation of metformin treatment to clinical events in diabetic patients undergoing percutaneous intervention | Q44912661 | ||
| Dietary supplementation with 2-deoxy-D-glucose improves cardiovascular and neuroendocrine stress adaptation in rats | Q45022807 | ||
| Systematic gene expression profile of hypothalamus in calorie-restricted mice implicates the involvement of mTOR signaling in neuroprotective activity. | Q45914381 | ||
| Neuroprotective potential of combination of resveratrol and 4-amino 1,8 naphthalimide in experimental diabetic neuropathy: focus on functional, sensorimotor and biochemical changes. | Q46085998 | ||
| Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation | Q46220928 | ||
| Metformin slows down aging and extends life span of female SHR mice. | Q46410425 | ||
| Glucose tolerance and skeletal muscle gene expression in response to alternate day fasting | Q46440389 | ||
| Pubertal adiposity after fetal growth restraint: toward a calorie restriction mimetic approach | Q46622057 | ||
| The role of NAD+ dependent histone deacetylases (sirtuins) in ageing | Q34000864 | ||
| Wine consumption and dementia in the elderly: a prospective community study in the Bordeaux area | Q34065159 | ||
| Histology and survival in age-delayed low-tryptophan-fed rats | Q34176646 | ||
| Methionine restriction increases blood glutathione and longevity in F344 rats. | Q34328305 | ||
| Low methionine ingestion by rats extends life span | Q34360084 | ||
| Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance | Q34422398 | ||
| Identification of potential caloric restriction mimetics by microarray profiling | Q34454584 | ||
| Alternate-day fasting in nonobese subjects: effects on body weight, body composition, and energy metabolism | Q34554026 | ||
| Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice | Q34560435 | ||
| Screening candidate longevity therapeutics using gene-expression arrays | Q34637850 | ||
| Sirtuins in aging and disease | Q34770789 | ||
| Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice | Q34796688 | ||
| Reducing insulin resistance with metformin: the evidence today | Q35539934 | ||
| Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma | Q35768291 | ||
| Lost in translation: dysregulation of cap-dependent translation and cancer | Q35802625 | ||
| Aminoguanidine prevents age-related arterial stiffening and cardiac hypertrophy | Q35805813 | ||
| Reduced oxidant stress and extended lifespan in mice exposed to a low glycotoxin diet: association with increased AGER1 expression | Q35855642 | ||
| The unfortunate influence of the weather on the rate of ageing: why human caloric restriction or its emulation may only extend life expectancy by 2-3 years | Q36041775 | ||
| Genetics of suicide | Q36389314 | ||
| Calorie restriction mimetics: an emerging research field | Q36454381 | ||
| Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan | Q36778201 | ||
| Inhibition of crystallin ascorbylation by nucleophilic compounds in the hSVCT2 mouse model of lenticular aging | Q36957704 | ||
| Glucosylation of human collagen in aging and diabetes mellitus | Q37025137 | ||
| The mTOR pathway as a potential target for the development of therapies against neurological disease | Q37031926 | ||
| Genes encoding longevity: from model organisms to humans | Q37061560 | ||
| Lowered methionine ingestion as responsible for the decrease in rodent mitochondrial oxidative stress in protein and dietary restriction possible implications for humans. | Q37077864 | ||
| Life-span extension in mice by preweaning food restriction and by methionine restriction in middle age | Q37215289 | ||
| Metformin therapy and clinical uses | Q37262966 | ||
| Sirtuins--novel therapeutic targets to treat age-associated diseases | Q37283448 | ||
| Caloric restriction-induced life extension of rats and mice: a critique of proposed mechanisms | Q37403940 | ||
| Treatment modalities for leptomeningeal metastases. | Q37574496 | ||
| Evaluating temsirolimus activity in multiple tumors: a review of clinical trials | Q37645019 | ||
| Naturally occurring phytochemicals for the prevention of Alzheimer's disease | Q37668715 | ||
| Cellular mechanism of action of metformin | Q37882736 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | calorie restriction | Q1332886 |
| lifetime | Q22675021 | ||
| health span | Q99337848 | ||
| P304 | page(s) | 695-703 | |
| P577 | publication date | 2010-07-01 | |
| P1433 | published in | The Journals of Gerontology | Q7743644 |
| P1476 | title | Dietary interventions to extend life span and health span based on calorie restriction | |
| P478 | volume | 65 |
| Q47670316 | Adaptive Immunity and Metabolic Health: Harmony Becomes Dissonant in Obesity and Aging |
| Q34322163 | Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies. |
| Q35142935 | Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta. |
| Q34062026 | Age-related changes in scavenger receptor-mediated endocytosis in rat liver sinusoidal endothelial cells |
| Q33558234 | Aging biology and novel targets for drug discovery |
| Q38872085 | Alzheimer's Disease: From Mitochondrial Perturbations to Mitochondrial Medicine |
| Q38121605 | An adipocentric perspective of resveratrol as a calorie restriction mimetic |
| Q42293272 | Behavioral and Stereological Analysis of the Effects of Intermittent Feeding Diet on the Orally Administrated MDMA ("ecstasy") in Mice |
| Q35353852 | Caloric restriction and chronic inflammatory diseases |
| Q24568041 | Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys |
| Q35093037 | Caloric restriction reveals a metabolomic and lipidomic signature in liver of male mice |
| Q91628100 | Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research |
| Q36971099 | Comparative gene expression and phenotype analyses of skeletal muscle from aged wild-type and PAPP-A-deficient mice |
| Q37265056 | Contributions of Nonhuman Primates to Research on Aging |
| Q37003167 | Decreased levels of proapoptotic factors and increased key regulators of mitochondrial biogenesis constitute new potential beneficial features of long-lived growth hormone receptor gene-disrupted mice. |
| Q33557923 | Determinants of serum-induced SIRT1 expression in older men: the CHAMP study |
| Q89623897 | Dietary Restriction and Epigenetics: Part I |
| Q21245677 | Effect of a 21 day Daniel Fast on metabolic and cardiovascular disease risk factors in men and women |
| Q47173962 | Effects of Intentional Weight Loss on Markers of Oxidative Stress, DNA Repair and Telomere Length - a Systematic Review |
| Q37179872 | Effects of Sirt1 on DNA methylation and expression of genes affected by dietary restriction |
| Q35110426 | Effects of calorie restriction on cardioprotection and cardiovascular health |
| Q38846461 | Factors That May Enhance Longevity: A Literature Review and a Comprehensive Update for Aesthetic Surgeons |
| Q38782067 | From yeast to human: exploring the comparative biology of methionine restriction in extending eukaryotic life span |
| Q38554542 | Improving the utility of colonoscopy: Recent advances in practice. |
| Q33701511 | Long-lived crowded-litter mice exhibit lasting effects on insulin sensitivity and energy homeostasis |
| Q37709586 | Longitudinal analysis of calorie restriction on rat taste bud morphology and expression of sweet taste modulators |
| Q35812392 | Macronutrients and caloric intake in health and longevity |
| Q34922762 | Metabolism, genomics, and DNA repair in the mouse aging liver |
| Q36068166 | Metallothionein and the biology of aging |
| Q35068752 | Mitochondrial protection by resveratrol. |
| Q34623917 | Protein and amino acid restriction, aging and disease: from yeast to humans |
| Q26866151 | Rapalogs in cancer prevention: anti-aging or anticancer? |
| Q40807364 | Resveratrol derivative-rich melinjo (Gnetum gnemon L.) seed extract improves obesity and survival of C57BL/6 mice fed a high-fat diet |
| Q33764609 | SIRT3 deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts |
| Q51574303 | SIRT6 Overexpression Improves Various Aspects of Mouse Healthspan. |
| Q36686883 | Short-term treatment with rapamycin and dietary restriction have overlapping and distinctive effects in young mice |
| Q40408814 | Six-month Calorie Restriction in Overweight Individuals Elicits Transcriptomic Response in Subcutaneous Adipose Tissue That is Distinct From Effects of Energy Deficit. |
| Q27685294 | Structures of human sirtuin 3 complexes with ADP-ribose and with carba-NAD+ and SRT1720: binding details and inhibition mechanism |
| Q58799389 | Switching from a high-fat cellulose diet to a high-fat pectin diet reverses certain obesity-related morbidities |
| Q28728880 | Testing the oxidative stress hypothesis of aging in primate fibroblasts: is there a correlation between species longevity and cellular ROS production? |
| Q36726997 | The conserved role of protein restriction in aging and disease |
| Q38683400 | The impact of low-protein high-carbohydrate diets on aging and lifespan |
| Q37702507 | Variation of lifespan in multiple strains, and effects of dietary restriction and BmFoxO on lifespan in silkworm, Bombyx mori |
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