Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits

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Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1036737682
P356DOI10.1038/NBT.2565
P3181OpenCitations bibliographic resource ID1807412
P932PMC publication ID3711863
P698PubMed publication ID23604284
P5875ResearchGate publication ID236252904

P50authorRobert KrencikQ37367953
Lixiang MaQ56867324
Xiaoqing ZhangQ56867325
P2093author name stringYan Liu
Huisheng Liu
Su-Chun Zhang
Melvin Ayala
Jason P Weick
Guo-min Zhou
P2860cites workFunctional Control of Transplantable Human ESC-Derived Neurons Via Optogenetic TargetingQ24569702
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Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's diseaseQ29615682
Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice.Q30512860
Quantitative histology using confocal microscopy: implementation of unbiased stereology proceduresQ31401089
Cre recombination-mediated cassette exchange for building versatile transgenic human embryonic stem cells linesQ33570136
Embryonic MGE precursor cells grafted into adult rat striatum integrate and ameliorate motor symptoms in 6-OHDA-lesioned ratsQ33822306
Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian ratsQ34115609
Induction and dorsoventral patterning of the telencephalonQ34132939
Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid.Q34156273
Specification of transplantable astroglial subtypes from human pluripotent stem cellsQ34186625
Damage of GABAergic neurons in the medial septum impairs spatial working memory and extinction of active avoidance: effects on proactive interference.Q34442143
Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signalsQ34599790
Alzheimer's disease and senile dementia: loss of neurons in the basal forebrainQ34714755
Dorsal-ventral patterning in the mammalian telencephalonQ35068988
The LIM-homeobox gene Lhx8 is required for the development of many cholinergic neurons in the mouse forebrainQ35171430
Glutamatergic systems in Alzheimer's disease.Q35218753
Human embryonic stem cell-derived neurons adopt and regulate the activity of an established neural networkQ35647648
Specification of midbrain dopamine neurons from primate pluripotent stem cellsQ36117009
Alzheimer's disease and neural transplantation as prospective cell therapy.Q36174570
Neural subtype specification from embryonic stem cellsQ36503816
Cholinergic systems in mammalian brain and spinal cordQ36882155
Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats.Q36954944
Delineation of multiple subpallial progenitor domains by the combinatorial expression of transcriptional codesQ37028020
Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small moleculesQ37254921
Human embryonic stem cell-derived dopaminergic neurons reverse functional deficit in parkinsonian ratsQ37255180
Functional neural development from human embryonic stem cells: accelerated synaptic activity via astrocyte coculture.Q37326553
Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage.Q37345661
Coordination of sonic hedgehog and Wnt signaling determines ventral and dorsal telencephalic neuron types from human embryonic stem cellsQ37424536
Regulation of neural specification from human embryonic stem cells by BMP and FGF.Q37460835
Differentiation of spinal motor neurons from pluripotent human stem cellsQ37460845
The controlled generation of functional basal forebrain cholinergic neurons from human embryonic stem cellsQ39580297
Trophic and growth-regulating mechanisms in the central nervous system monitored by intracerebral neural transplants.Q39768702
GDNF-secreting human neural progenitor cells increase tyrosine hydroxylase and VMAT2 expression in MPTP-treated cynomolgus monkeysQ39975890
Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes.Q40216832
L3/Lhx8 is involved in the determination of cholinergic or GABAergic cell fateQ40401397
Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells.Q40876310
Regionalization of the prosencephalic neural plate.Q41733317
Selective immunolesions of cholinergic neurons in mice: effects on neuroanatomy, neurochemistry, and behavior.Q42510981
Cooperative effects of Sonic Hedgehog and NGF on basal forebrain cholinergic neuronsQ42516582
Injection of IgG 192-saporin into the medial septum produces cholinergic hypofunction and dose-dependent working memory deficitsQ42524259
Noncholinergic lesions of the medial septum impair sequential learning of different spatial locations.Q42703466
In vitro differentiation of transplantable neural precursors from human embryonic stem cellsQ43814659
Grafts of fetal septal cells after cholinergic immunotoxic denervation of the hippocampus: a functional dissociation between dorsal and ventral implantation sitesQ44105487
Septohippocampal pathways contribute to system consolidation of a spatial memory: sequential implication of GABAergic and cholinergic neuronsQ44364238
Specification of motoneurons from human embryonic stem cells.Q45246951
Enhancer-specified GFP-based FACS purification of human spinal motor neurons from embryonic stem cellsQ46730802
Amelioration of spatial navigation and short-term memory deficits by grafts of foetal basal forebrain tissue placed into the hippocampus and cortex of rats with selective cholinergic lesionsQ48388955
Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditionsQ48435042
Intrahippocampal septal grafts ameliorate learning impairments in aged ratsQ48635415
Subregional specification of embryonic stem cell-derived ventral telencephalic tissues by timed and combinatory treatment with extrinsic signals.Q51889739
Regional and laminar differences in antigen profiles and spatial distributions of astrocytes in the mouse hippocampus, with reference to agingQ83410142
A fresh look at iPS cellsQ83608099
P4510describes a project that usesImageJQ1659584
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectbiomedical engineeringQ327092
bioengineeringQ580689
human embryonic stem cellQ59626782
P304page(s)440-447
P577publication date2013-04-21
P1433published inNature BiotechnologyQ1893837
P1476titleMedial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits
P478volume31

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