Effects of neural stem cell transplantation in Alzheimer's disease models

scientific article published on 27 January 2020

Effects of neural stem cell transplantation in Alzheimer's disease models is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1186/S12929-020-0622-X
P932PMC publication ID6986162
P698PubMed publication ID31987051

P50authorKuen-Jer TsaiQ48943781
P2093author name stringYoshihito Hayashi
Cheng-Che Lee
Huan-Ting Lin
P2860cites workHuman Neural Stem Cells Reinforce Hippocampal Synaptic Network and Rescue Cognitive Deficits in a Mouse Model of Alzheimer's DiseaseQ91421961
Questions EMERGE as Biogen claims aducanumab turnaroundQ91560063
Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progressionQ93134029
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic MiceQ22242267
Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficitsQ24598809
Induced pluripotent stem cells in Alzheimer's disease: applications for disease modeling and cell-replacement therapyQ26749360
Potential of Neural Stem Cell-Based Therapy for Parkinson's DiseaseQ26776154
Cancer stem cells in brain tumors and their lineage hierarchyQ26992115
Inconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer's diseaseQ27003841
Gain of BDNF Function in Engrafted Neural Stem Cells Promotes the Therapeutic Potential for Alzheimer's Disease.Q27345509
The antibody aducanumab reduces Aβ plaques in Alzheimer’s diseaseQ28005463
Choices for Induction of Pluripotency: Recent Developments in Human Induced Pluripotent Stem Cell Reprogramming StrategiesQ28085565
Neuropathologic changes in Alzheimer's diseaseQ28203182
Delayed increase of Ca2+ influx elicited by glutamate: role in neuronal deathQ28257073
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunctionQ29547778
Isolation of multipotent neural stem or progenitor cells from both the dentate gyrus and subventricular zone of a single adult mouse.Q30539757
Neural Stem Cell Transplant-Induced Effect on Neurogenesis and Cognition in Alzheimer Tg2576 Mice Is Inhibited by Concomitant Treatment with Amyloid-Lowering or Cholinergic α7 Nicotinic Receptor DrugsQ30659307
Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.Q31840691
Stem Cells Transplantation and Huntington's DiseaseQ33614689
The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neuronsQ33725851
Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic modelsQ33746410
Drugs for Alzheimer's disease: are they effective?Q33865325
Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system--too little activation is bad, too much is even worseQ34007194
Combined effect of nerve growth factor and brain‑derived neurotrophic factor on neuronal differentiation of neural stem cells and the potential molecular mechanismsQ34105254
Current and future treatments for Alzheimer's diseaseQ34646921
Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathologyQ35016226
Chemokine receptors: signposts to brain development and diseaseQ35141737
A combination Alzheimer's therapy targeting BACE1 and neprilysin in 5XFAD transgenic miceQ35426661
Cumulative, additive benefits of memantine-donepezil combination over component monotherapies in moderate to severe Alzheimer's dementia: a pooled area under the curve analysisQ35620305
Neural stem cell transplantation at critical period improves learning and memory through restoring synaptic impairment in Alzheimer's disease mouse modelQ36347323
Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal lossQ36490240
Effect of Astragaloside IV on Neural Stem Cell Transplantation in Alzheimer's Disease Rat ModelsQ36725913
Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.Q37273874
In Vivo Tracking of Human Neural Progenitor Cells in the Rat Brain Using Magnetic Resonance Imaging Is Not Enhanced by Ferritin ExpressionQ37315468
Human Neural Stem Cell Transplantation Rescues Cognitive Defects in APP/PS1 Model of Alzheimer's Disease by Enhancing Neuronal Connectivity and Metabolic ActivityQ37430416
HuCNS-SC Human NSCs Fail to Differentiate, Form Ectopic Clusters, and Provide No Cognitive Benefits in a Transgenic Model of Alzheimer's Disease.Q37644720
Maintenance and differentiation of neural stem cellsQ37808164
Progress in stem cell therapy for major human neurological disorders.Q38107439
Induced neural stem cells (iNSCs) in neurodegenerative diseasesQ38110478
Vaccination against Alzheimer disease: an update on future strategiesQ38188866
Drug treatments in Alzheimer's disease.Q38850887
Production of neural stem cells from human pluripotent stem cellsQ38963472
Neural stem cell therapy for neurodegenerative disorders: The role of neurotrophic support.Q39144600
Neural stem cell replacement: a possible therapy for neurodevelopmental disorders?Q39490571
Neural stem cell transplantation decreases neuroinflammation in a transgenic mouse model of Alzheimer's diseaseQ40365868
The Crossroads of Neural Stem Cell Development and TumorigenesisQ41283587
Developing neural stem cell-based treatments for neurodegenerative diseasesQ41547468
Neural stem cell transplantation enhances mitochondrial biogenesis in a transgenic mouse model of Alzheimer's disease-like pathologyQ41591159
Modeling familial Alzheimer's disease with induced pluripotent stem cellsQ42817521
Stem Cell Tracking Technologies for Neurological Regenerative Medicine Purposes.Q43375861
Neural stem cell transplantation improves spatial learning and memory via neuronal regeneration in amyloid-β precursor protein/presenilin 1/tau triple transgenic miceQ43494602
Neural stem cell transplantation in mouse brainQ43798772
Changes in amyloid-β and Tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor proteinQ43861573
Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic miceQ44182586
Neural stem cells improve memory in an inducible mouse model of neuronal loss.Q44339825
Mutation screening of the tau gene in patients with early-onset Alzheimer's diseaseQ44468725
Effects of neural stem cells on synaptic proteins and memory in a mouse model of Alzheimer's diseaseQ44763772
Effective drug therapy for Alzheimer's disease remains elusiveQ45148787
Embryonic stem cell-derived neural precursor cells improve memory dysfunction in Abeta(1-40) injured ratsQ46805283
Trial of Solanezumab for Mild Dementia Due to Alzheimer's DiseaseQ47552349
Reprogramming of somatic cells to induced neural stem cellsQ47645196
Stem cell transplantation for Huntington's diseasesQ47722179
Towards stem cell based therapies for Parkinson's diseaseQ47877645
Alzheimer's disease in the 100 years since Alzheimer's deathQ47918885
Transplantation of NSC-derived cholinergic neuron-like cells improves cognitive function in APP/PS1 transgenic miceQ48329246
Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.Q48404445
APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.Q48629595
Thrombospondin-1 secreted by human umbilical cord blood-derived mesenchymal stem cells rescues neurons from synaptic dysfunction in Alzheimer's disease modelQ49367941
iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer's Disease.Q49793536
Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease.Q50681098
Neural stem cell transplants improve cognitive function without altering amyloid pathology in an APP/PS1 double transgenic model of Alzheimer's disease.Q50692044
Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months.Q52012764
Current Perspectives regarding Stem Cell-Based Therapy for Alzheimer's Disease.Q52568314
Ten years of progress and promise of induced pluripotent stem cells: historical origins, characteristics, mechanisms, limitations, and potential applications.Q55314338
Human neural stem cell transplantation improves cognition in a murine model of Alzheimer's diseaseQ57041817
Inflammation as a central mechanism in Alzheimer's diseaseQ58555818
Trends in Alzheimer's Disease Research Based upon Machine Learning Analysis of PubMed AbstractsQ90581926
P433issue1
P921main subjectAlzheimer's diseaseQ11081
neural stem cellQ2944097
stem cell transplantationQ65592366
P304page(s)29
P577publication date2020-01-27
P1433published inJournal of Biomedical ScienceQ15759332
P1476titleEffects of neural stem cell transplantation in Alzheimer's disease models
P478volume27