Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation

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Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1101/GAD.834100
P3181OpenCitations bibliographic resource ID636120
P932PMC publication ID316999
P698PubMed publication ID11040213
P5875ResearchGate publication ID277503684

P2093author name stringM G O'Sullivan
V J Bardwell
D Zarkower
C S Raymond
M W Murphy
P2860cites workThe region on 9p associated with 46,XY sex reversal contains several transcripts expressed in the urogenital system and a novel doublesex-related domainQ22253379
Dax1 antagonizes Sry action in mammalian sex determinationQ28508912
A Drosophila doublesex-related gene, terra, is involved in somitogenesis in vertebratesQ28510747
WT-1 is required for early kidney developmentQ28512266
Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cellsQ28513440
A male-specific role for SOX9 in vertebrate sex determinationQ28594894
An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombinationQ29615355
Courtship anomalies caused by doublesex mutations in Drosophila melanogasterQ30498655
Deletion 9p and sex reversalQ33595492
Impaired male sex development in an infant with molecularly defined partial 9p monosomy: implication for a testis forming gene(s) on 9p.Q33678714
A region of human chromosome 9p required for testis development contains two genes related to known sexual regulators.Q33862499
Expression of Dmrt1 in the genital ridge of mouse and chicken embryos suggests a role in vertebrate sexual developmentQ33878782
Conservation of a sex-determining geneQ33884153
A new submicroscopic deletion that refines the 9p region for sex reversalQ33905990
Sex and the single cell. I. On the action of major loci affecting sex determination in Drosophila melanogasterQ33994066
The Drosophila doublesex proteins share a novel zinc finger related DNA binding domain.Q34043122
mab-3, a gene required for sex-specific yolk protein expression and a male-specific lineage in C. elegansQ34163866
A gene involved in XY sex reversal is located on chromosome 9, distal to marker D9S1779Q34387052
Sertoli cell signaling by Desert hedgehog regulates the male germlineQ34396888
Evidence for evolutionary conservation of sex-determining genesQ34459101
Similarity of DNA binding and transcriptional regulation by Caenorhabditis elegans MAB-3 and Drosophila melanogaster DSX suggests conservation of sex determining mechanisms.Q34490364
Transmeiotic differentiation of male germ cells in cultureQ38313631
Sequence and expression analysis of WT1 and Sox9 in the red-eared slider turtle, Trachemys scriptaQ38335553
Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birdsQ38353588
Molecular analysis of 9p deletions associated with XY sex reversal: refining the localization of a sex-determining gene to the tip of the chromosomeQ43217795
Swyer syndrome and 46,XY partial gonadal dysgenesis associated with 9p deletions in the absence of monosomy-9p syndromeQ43217805
Analysis of Fgf8 gene function in vertebrate developmentQ46135598
Mab-3 is a direct tra-1 target gene regulating diverse aspects of C. elegans male sexual development and behaviorQ47068980
Sex-specific transcriptional regulation by the male and female doublesex proteins of DrosophilaQ47071899
Early expression of AMH in chicken embryonic gonads precedes testicular SOX9 expressionQ47675270
Temperature-dependent sex determination: upregulation of SOX9 expression after commitment to male developmentQ47978023
300 million years of conserved synteny between chicken Z and human chromosome 9.Q47979568
Failure of testicular development associated with a rearrangement of 9p24.1 proximal to the SNF2 gene.Q50899667
Deletions of distal 9p associated with 46,XY male to female sex reversal: definition of the breakpoints at 9p23.3-p24.1.Q50956714
The expression pattern of a mouse doublesex-related gene is consistent with a role in gonadal differentiation.Q52575823
Coral growing on North Sea oil rigsQ55878248
An unbalanced autosomal translocation (7;9) associated with feminizationQ68485220
Differential expression of SOX9 in gonads of the sea turtle Lepidochelys olivacea at male- or female-promoting temperaturesQ73107576
Male specific expression suggests role of DMRT1 in human sex determinationQ73515685
Temperature-dependent expression of turtle Dmrt1 prior to sexual differentiationQ73516895
P433issue20
P407language of work or nameEnglishQ1860
P921main subjectDoublesex and mab-3 related transcription factor 1Q21983233
P304page(s)2587-95
P577publication date2000-10-15
P1433published inGenes & DevelopmentQ1524533
P1476titleDmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation
P478volume14

Reverse relations

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Q34131622The birds and the bees and the flowers and the trees: lessons from genetic mapping of sex determination in plants and animals
Q52695771The creation of sexual dimorphism in the Drosophila soma.
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Q36819789The germline-enriched Ppp1r36 promotes autophagy
Q28591857The mammalian DM domain transcription factor Dmrta2 is required for early embryonic development of the cerebral cortex
Q34341421The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis
Q28588842The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells
Q28505603The mammalian twisted gastrulation gene functions in foregut and craniofacial development
Q38083053The molecular genetics of avian sex determination and its manipulation.
Q38044183The molecular genetics of ovarian differentiation in the avian model.
Q38297659The nuclear localization signal of zebrafish terra is located within the DM domain
Q27030859The sex chromosomes of frogs: variability and tolerance offer clues to genome evolution and function
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Q34514303Transcriptional diversity of DMRT1 (dsx- and mab3-related transcription factor 1) in human testis.
Q34321651Transcriptome analysis of the oriental river prawn, Macrobrachium nipponense using 454 pyrosequencing for discovery of genes and markers
Q33740037Tumor loci and their interactions on mouse chromosome 19 that contribute to testicular germ cell tumors
Q34999143UPF2, a nonsense-mediated mRNA decay factor, is required for prepubertal Sertoli cell development and male fertility by ensuring fidelity of the transcriptome
Q38675326Understanding sex determination in the mouse: genetics, epigenetics and the story of mutual antagonisms.
Q28588326Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA
Q52114896Vertebrate sex determination: a new player in the field.
Q38626969Vertebrate sex determination: evolutionary plasticity of a fundamental switch.
Q28076597Zebrafish Germ Cell Tumors
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