The avian Z-linked gene DMRT1 is required for male sex determination in the chicken

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The avian Z-linked gene DMRT1 is required for male sex determination in the chicken is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1026768312
P356DOI10.1038/NATURE08298
P698PubMed publication ID19710650
P5875ResearchGate publication ID26770624

P2093author name stringAndrew H Sinclair
Timothy J Doran
Peter G Farlie
David M Cummins
Thomas Ohnesorg
Craig A Smith
Kelly N Roeszler
P2860cites workDmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiationQ24599580
Avian sex determination: what, when and where?Q28239395
A male-specific role for SOX9 in vertebrate sex determinationQ28594894
Wpkci, encoding an altered form of PKCI, is conserved widely on the avian W chromosome and expressed in early female embryos: implication of its role in female sex determinationQ30940279
Cloning and expression of R-Spondin1 in different vertebrates suggests a conserved role in ovarian developmentQ33354658
Conservation of a sex-determining geneQ33884153
DMRT1 is upregulated in the gonads during female-to-male sex reversal in ZW chicken embryosQ34171259
Z and W chromosomes of chickens: studies on their gene functions in sex determination and sex differentiationQ35192740
Sex determination: insights from the chicken.Q35639942
A W-linked DM-domain gene, DM-W, participates in primary ovary development in Xenopus laevis.Q36497313
Sex determination in birds: HINTs from the W sex chromosome?Q37129446
Multiple alternative splicing in gonads of chicken DMRT1.Q38307422
Synteny conservation of the Z chromosome in 14 avian species (11 families) supports a role for Z dosage in avian sex determinationQ38452683
Characterization and comparison of chicken U6 promoters for the expression of short hairpin RNAs.Q40197306
DMRT1 in a ratite bird: evidence for a role in sex determination and discovery of a putative regulatory element.Q42605171
Isolation of chicken homolog of the FOXL2 gene and comparison of its expression patterns with those of aromatase during ovarian developmentQ42639343
Robust and ubiquitous GFP expression in a single generation of chicken embryos using the avian retroviral vector, RCASBP.Q44320531
Aromatase enzyme activity and sex determination in chickensQ46124648
Mechanism of asymmetric ovarian development in chick embryos.Q46805081
300 million years of conserved synteny between chicken Z and human chromosome 9.Q47979568
DMY is a Y-specific DM-domain gene required for male development in the medaka fishQ48301209
PITX2 controls asymmetric gonadal development in both sexes of the chick and can rescue the degeneration of the right ovary.Q51731204
Expression of Sox9, Mis, and Dmrt1 in the gonad of a species with temperature-dependent sex determination.Q51993322
Sex-specific expression of an evolutionarily conserved male regulatory gene, DMRT1, in birds.Q52165675
Observation of a ZZW female in a natural population: implications for avian sex determination.Q54710148
Conserved synteny between the chicken Z sex chromosome and human chromosome 9 includes the male regulatory gene DMRT1: a comparative (re)view on avian sex determination.Q55034053
Coral growing on North Sea oil rigsQ55878248
Temperature-dependent expression of turtle Dmrt1 prior to sexual differentiationQ73516895
Evolution of the avian sex chromosomes and their role in sex determinationQ73713927
Targeted gene misexpression in chick limb buds using avian replication-competent retrovirusesQ74603313
Three patients with 9p deletions including DMRT1 and DMRT2: a girl with XY complement, bilateral ovotestes, and extreme growth retardation, and two XX females with normal pubertal developmentQ80853343
P433issue7261
P407language of work or nameEnglishQ1860
P921main subjectsex-determination systemQ594595
P304page(s)267-271
P577publication date2009-08-26
P1433published inNatureQ180445
P1476titleThe avian Z-linked gene DMRT1 is required for male sex determination in the chicken
P478volume461

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cites work (P2860)
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Q33641481Sex reversal in zebrafish fancl mutants is caused by Tp53-mediated germ cell apoptosis
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Q35196437Sexual cell-fate reprogramming in the ovary by DMRT1.
Q34874792Sexually dimorphic and sex-independent left-right asymmetries in chicken embryonic gonads
Q36766777Sexually dimorphic expression of Dmrt1 and γH2AX in germ stem cells during gonadal development in Xenopus laevis
Q35614513Single locus sex determination and female heterogamety in the basket willow (Salix viminalis L.).
Q35822176Small but mighty: the evolutionary dynamics of W and Y sex chromosomes.
Q28659020Somatic sex identity is cell autonomous in the chicken
Q34203619Some inconvenient truths about sex chromosome dosage compensation and the potential role of sexual conflict.
Q46909055Spatiotemporal expression patterns of doublesex and mab-3 related transcription factor 1 in the chicken developing gonads and Mullerian ducts
Q34132123Temperature-dependent turnovers in sex-determination mechanisms: a quantitative model
Q34746430Temporal genomic evolution of bird sex chromosomes
Q34047301The Staurotypus turtles and aves share the same origin of sex chromosomes but evolved different types of heterogametic sex determination
Q61443569The Y chromosome sequence of the channel catfish suggests novel sex determination mechanisms in teleost fish
Q45815529The ZW sex microchromosomes of an Australian dragon lizard share no homology with those of other reptiles or birds
Q34131622The birds and the bees and the flowers and the trees: lessons from genetic mapping of sex determination in plants and animals
Q50491124The cloning and expression analysis of Lhx9 during gonadal sex differentiation in the red-eared slider turtle, Trachemys scripta, a species with temperature-dependent sex determination.
Q62059521The epigenetic sole of sex and dosage compensation
Q34864525The expanding epigenetic landscape of non-model organisms
Q36805909The fate of W chromosomes in hybrids between wild silkmoths, Samia cynthia ssp.: no role in sex determination and reproduction
Q37778485The game plan: cellular and molecular mechanisms of mammalian testis development
Q36990855The genetic contribution to sex determination and number of sex chromosomes vary among populations of common frogs (Rana temporaria).
Q36432991The genetics of sex chromosomes: evolution and implications for hybrid incompatibility
Q36081263The long and the short of avian W chromosomes: no evidence for gradual W shortening
Q28588842The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells
Q30432195The mechanisms underlying sexual differentiation of behavior and physiology in mammals and birds: relative contributions of sex steroids and sex chromosomes
Q38083053The molecular genetics of avian sex determination and its manipulation.
Q38044183The molecular genetics of ovarian differentiation in the avian model.
Q35614281The origin and evolution of vertebrate sex chromosomes and dosage compensation
Q37967466The potential role of microRNAs in regulating gonadal sex differentiation in the chicken embryo.
Q38597347The role of Amh signaling in teleost fish--Multiple functions not restricted to the gonads
Q34045997The sex-specific transcriptome of the hermaphrodite sparid sharpsnout seabream (Diplodus puntazzo)
Q36904953The sexually dimorphic on the Y-chromosome gene (sdY) is a conserved male-specific Y-chromosome sequence in many salmonids.
Q37992873The switch of secondary sex determination in protandrous black porgy, Acanthopagrus schlegeli
Q50145691The transcriptomic signature of different sexes in two protogynous hermaphrodites: Insights into the molecular network underlying sex phenotype in fish.
Q51539169The transformer gene of Ceratitis capitata: a paradigm for a conserved epigenetic master regulator of sex determination in insects.
Q93335831The unusual rainbow trout sex determination gene hijacked the canonical vertebrate gonadal differentiation pathway
Q41942019The variety of vertebrate mechanisms of sex determination
Q51173661Timing sexual differentiation: full functional sex reversal achieved through silencing of a single insulin-like gene in the prawn, Macrobrachium rosenbergii.
Q46310690Trans-species variation in Dmrt1 is associated with sex determination in four European tree-frog species
Q42773793Transcriptome Display During Testicular Differentiation of Channel Catfish (Ictalurus punctatus) as Revealed by RNA-Seq Analysis.
Q34321651Transcriptome analysis of the oriental river prawn, Macrobrachium nipponense using 454 pyrosequencing for discovery of genes and markers
Q55261552Transcriptome display during tilapia sex determination and differentiation as revealed by RNA-Seq analysis.
Q37145168Transcriptome sequencing reveals the character of incomplete dosage compensation across multiple tissues in flycatchers.
Q38646254Transcriptomic analysis of the differentiating ovary of the protogynous ricefield eel Monopterus albus
Q36308889Transcriptomic responses to environmental temperature by turtles with temperature-dependent and genotypic sex determination assessed by RNAseq inform the genetic architecture of embryonic gonadal development
Q27308219Transgenic Expression of the piRNA-Resistant Masculinizer Gene Induces Female-Specific Lethality and Partial Female-to-Male Sex Reversal in the Silkworm, Bombyx mori
Q34286836Triploid plover female provides support for a role of the W chromosome in avian sex determination.
Q36383136Turnover of Sex Chromosomes in Celebensis Group Medaka Fishes.
Q28741765Unexpected resilience of species with temperature-dependent sex determination at the Cretaceous-Palaeogene boundary
Q46387377Unstable Linkage of Molecular Markers with Sex Determination Gene in Pacific Salmon (Oncorhynchus spp.).
Q28752088Variability in sex-determining mechanisms influences genome complexity in reptilia
Q38626969Vertebrate sex determination: evolutionary plasticity of a fundamental switch.
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