review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Wolf-Dietrich Heyer | Q63309380 |
P2093 | author name string | Xuan Li | |
P2860 | cites work | Cellular roles of dna topoisomerases: a molecular perspective | Q22121990 |
Evidence for simultaneous protein interactions between human Rad51 paralogs | Q22253453 | ||
Identification and purification of two distinct complexes containing the five RAD51 paralogs | Q24292055 | ||
CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair | Q24299313 | ||
Analysis of the DNA substrate specificity of the human BACH1 helicase associated with breast cancer | Q24301530 | ||
Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis | Q24301697 | ||
RAD51C is required for Holliday junction processing in mammalian cells | Q24304325 | ||
Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats | Q24306511 | ||
Insights into DNA recombination from the structure of a RAD51-BRCA2 complex | Q24319669 | ||
Multiple heterologies increase mitotic double-strand break-induced allelic gene conversion tract lengths in yeast. | Q34607778 | ||
Maintenance of genome stability in Saccharomyces cerevisiae | Q34762852 | ||
Translesion DNA synthesis in eukaryotes: a one- or two-polymerase affair | Q34770150 | ||
Rad54: the Swiss Army knife of homologous recombination? | Q35100612 | ||
Rad54, a Jack of all trades in homologous recombination | Q35162506 | ||
Holliday junctions in the eukaryotic nucleus: resolution in sight? | Q35559727 | ||
The Mus81 solution to resolution: generating meiotic crossovers without Holliday junctions | Q35643073 | ||
Emerging functions of BRCA2 in DNA recombination | Q35846734 | ||
Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences | Q36037736 | ||
BLM ortholog, Sgs1, prevents aberrant crossing-over by suppressing formation of multichromatid joint molecules | Q36082370 | ||
Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide. | Q36143372 | ||
The Fanconi Anemia/BRCA pathway: new faces in the crowd | Q36343120 | ||
Loss of heterozygosity induced by a chromosomal double-strand break | Q36546233 | ||
Exonuclease I of Saccharomyces cerevisiae functions in mitotic recombination in vivo and in vitro | Q36568265 | ||
DNA interstrand cross-link repair in Saccharomyces cerevisiae. | Q36649807 | ||
Fanconi anemia and DNA replication repair | Q36811854 | ||
Chromosome fragility: molecular mechanisms and cellular consequences | Q36849639 | ||
RAD54 controls access to the invading 3'-OH end after RAD51-mediated DNA strand invasion in homologous recombination in Saccharomyces cerevisiae | Q37077426 | ||
Sws1 is a conserved regulator of homologous recombination in eukaryotic cells | Q24337352 | ||
The Stability of Broken Ends of Chromosomes in Zea Mays. | Q24533277 | ||
Structure of the single-strand annealing domain of human RAD52 protein | Q24536071 | ||
BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates | Q24544999 | ||
Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae | Q24548535 | ||
Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1 | Q24551095 | ||
The Rad51 paralog Rad51B promotes homologous recombinational repair | Q24551864 | ||
Disruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin C | Q24554173 | ||
The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamily | Q24555147 | ||
The BRCA2-interacting protein BCCIP functions in RAD51 and BRCA2 focus formation and homologous recombinational repair | Q24556631 | ||
Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange | Q24599514 | ||
A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M | Q24654206 | ||
The hSNM1 protein is a DNA 5'-exonuclease | Q24671253 | ||
Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair | Q24685928 | ||
Differential and collaborative actions of Rad51 paralog proteins in cellular response to DNA damage | Q24812447 | ||
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure | Q27639649 | ||
Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing | Q27930553 | ||
In vivo roles of Rad52, Rad54, and Rad55 proteins in Rad51-mediated recombination. | Q27930596 | ||
Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes | Q27931495 | ||
A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage | Q27931627 | ||
Mre11 and Ku regulation of double-strand break repair by gene conversion and break-induced replication | Q27932084 | ||
Break-induced replication and telomerase-independent telomere maintenance require Pol32. | Q27933035 | ||
Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes | Q27933322 | ||
Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein | Q27933995 | ||
The S. cerevisiae Rrm3p DNA helicase moves with the replication fork and affects replication of all yeast chromosomes | Q27934054 | ||
The yeast Snm1 protein is a DNA 5'-exonuclease | Q27934200 | ||
The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments. | Q27934939 | ||
The beta-lactamase motif in Snm1 is required for repair of DNA double-strand breaks caused by interstrand crosslinks in S. cerevisiae | Q27935474 | ||
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. | Q27937465 | ||
Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein | Q27937922 | ||
Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase | Q27938070 | ||
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1 | Q27938100 | ||
CeBRC-2 stimulates D-loop formation by RAD-51 and promotes DNA single-strand annealing | Q33250311 | ||
Topoisomerase IIIalpha and Bloom's helicase can resolve a mobile double Holliday junction substrate through convergent branch migration | Q33250631 | ||
Rad52-mediated DNA annealing after Rad51-mediated DNA strand exchange promotes second ssDNA capture | Q33263102 | ||
FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein | Q33289084 | ||
A surfeit of RAD51-like genes? | Q33633019 | ||
Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation | Q33781473 | ||
DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability | Q34164868 | ||
Tumor cell death induced by topoisomerase-targeting drugs. | Q34192665 | ||
Crystal structure of a Rad51 filament | Q34331322 | ||
Efficient copying of nonhomologous sequences from ectopic sites via P-element-induced gap repair | Q34336201 | ||
Repair of DNA interstrand cross-links | Q34343361 | ||
Recombination and recombination-dependent DNA replication in bacteriophage T4. | Q34490524 | ||
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2. | Q34541051 | ||
DNA double-strand break repair: all's well that ends well | Q34555274 | ||
Repair of DNA interstrand crosslinks: molecular mechanisms and clinical relevance. | Q34571928 | ||
Double-strand breaks and translocations in cancer | Q34578131 | ||
Mobile D-loops are a preferred substrate for the Bloom's syndrome helicase. | Q34588305 | ||
Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer | Q34597168 | ||
Fanconi anemia is associated with a defect in the BRCA2 partner PALB2. | Q34597176 | ||
Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication | Q37490114 | ||
Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae | Q38308503 | ||
The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks | Q38774142 | ||
Phosphorylation of Rad55 on serines 2, 8, and 14 is required for efficient homologous recombination in the recovery of stalled replication forks | Q39126666 | ||
Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells | Q39456389 | ||
DNA replication is required To elicit cellular responses to psoralen-induced DNA interstrand cross-links. | Q39456549 | ||
The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway. | Q40382206 | ||
Malondialdehyde, a product of lipid peroxidation, is mutagenic in human cells | Q40643885 | ||
Telomere maintenance by recombination in human cells. | Q40839283 | ||
Frequent chromosomal translocations induced by DNA double-strand breaks | Q40872179 | ||
DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: bleomycin, neocarzinostatin and other enediynes | Q41090666 | ||
Shu proteins promote the formation of homologous recombination intermediates that are processed by Sgs1-Rmi1-Top3. | Q41312383 | ||
Sgs1 regulates gene conversion tract lengths and crossovers independently of its helicase activity | Q41493782 | ||
The F-Box DNA helicase Fbh1 prevents Rhp51-dependent recombination without mediator proteins. | Q42107587 | ||
Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2. | Q42152324 | ||
Rad54, a Swi2/Snf2-like recombinational repair protein, disassembles Rad51:dsDNA filaments | Q44230461 | ||
Rad54p is a chromatin remodeling enzyme required for heteroduplex DNA joint formation with chromatin | Q44270140 | ||
ATP-dependent and ATP-independent roles for the Rad54 chromatin remodeling enzyme during recombinational repair of a DNA double strand break | Q45226582 | ||
The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction | Q45345099 | ||
Rad54 protein is targeted to pairing loci by the Rad51 nucleoprotein filament | Q46189017 | ||
Visualization of Rad54, a chromatin remodeling protein, translocating on single DNA molecules | Q46202156 | ||
The DNA binding properties of Saccharomyces cerevisiae Rad51 protein | Q46561573 | ||
Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p | Q46576875 | ||
Replication fork reactivation downstream of a blocked nascent leading strand | Q46923728 | ||
Drosophila BLM in double-strand break repair by synthesis-dependent strand annealing | Q47071772 | ||
Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM. | Q47074397 | ||
DNA strand exchange proteins: a biochemical and physical comparison. | Q47956058 | ||
High-frequency P element loss in Drosophila is homolog dependent. | Q52449709 | ||
Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination. | Q52524907 | ||
The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends. | Q53657324 | ||
BRCA2-dependent and independent formation of RAD51 nuclear foci. | Q53939630 | ||
RMPs: recombination/replication mediator proteins | Q56896449 | ||
Similarity of the yeast RAD51 filament to the bacterial RecA filament | Q56937925 | ||
Multiple Mechanisms Control Chromosome Integrity after Replication Fork Uncoupling and Restart at Irreparable UV Lesions | Q58883733 | ||
Antitumour drugs impede DNA uncoiling by topoisomerase I | Q59092676 | ||
Rad54 dissociates homologous recombination intermediates by branch migration | Q64387873 | ||
Synapsis and the formation of paranemic joints by E. coli RecA protein | Q70168677 | ||
Superhelicity-driven homologous DNA pairing by yeast recombination factors Rad51 and Rad54 | Q73074482 | ||
A novel function of Rad54 protein. Stabilization of the Rad51 nucleoprotein filament | Q78882309 | ||
The BRCA2-Interacting Protein DSS1 Is Vital for DNA Repair, Recombination, and Genome Stability in Ustilago maydis | Q79212406 | ||
Homology-driven chromatin remodeling by human RAD54 | Q80119033 | ||
Rad54 protein possesses chromatin-remodeling activity stimulated by the Rad51-ssDNA nucleoprotein filament | Q27938152 | ||
A genetic screen for top3 suppressors in Saccharomyces cerevisiae identifies SHU1, SHU2, PSY3 and CSM2: four genes involved in error-free DNA repair | Q27939159 | ||
In vivo assembly and disassembly of Rad51 and Rad52 complexes during double-strand break repair | Q27939283 | ||
MUS81 encodes a novel helix-hairpin-helix protein involved in the response to UV- and methylation-induced DNA damage in Saccharomyces cerevisiae | Q27939646 | ||
Genome maintenance mechanisms for preventing cancer | Q28131737 | ||
Molecular views of recombination proteins and their control | Q28207872 | ||
Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects | Q28216078 | ||
SWI2/SNF2 and related proteins: ATP-driven motors that disrupt protein-DNA interactions? | Q28236020 | ||
Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2 | Q28236543 | ||
Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism | Q28245231 | ||
Rad54 protein promotes branch migration of Holliday junctions | Q28253660 | ||
SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase | Q28254244 | ||
Mechanism of homologous recombination: mediators and helicases take on regulatory functions | Q28259452 | ||
Stimulation by Rad52 of yeast Rad51-mediated recombination | Q28260489 | ||
Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A | Q28260499 | ||
The double-strand-break repair model for recombination | Q28267259 | ||
Replisome assembly and the direct restart of stalled replication forks | Q28276681 | ||
Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells | Q28511551 | ||
DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells | Q28586983 | ||
The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks | Q28592473 | ||
A single-stranded DNA-binding protein is needed for efficient presynaptic complex formation by the Saccharomyces cerevisiae Rad51 protein | Q28647553 | ||
The Bloom's syndrome helicase suppresses crossing over during homologous recombination | Q29547237 | ||
Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins | Q29615270 | ||
Recombination proteins in yeast | Q29617872 | ||
DNA helicase Srs2 disrupts the Rad51 presynaptic filament | Q29618305 | ||
RecQ helicases: caretakers of the genome | Q29618390 | ||
Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast | Q29618612 | ||
Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation | Q29619155 | ||
Recombinational repair of DNA damage in Escherichia coli and bacteriophage lambda | Q29619755 | ||
Function of yeast Rad52 protein as a mediator between replication protein A and the Rad51 recombinase | Q29620205 | ||
Rad52 partially substitutes for the Rad51 paralog XRCC3 in maintaining chromosomal integrity in vertebrate cells | Q30453366 | ||
Rad52 protein associates with replication protein A (RPA)-single-stranded DNA to accelerate Rad51-mediated displacement of RPA and presynaptic complex formation | Q30736645 | ||
Studies of the interaction between Rad52 protein and the yeast single-stranded DNA binding protein RPA. | Q32060621 | ||
DNA annealing by RAD52 protein is stimulated by specific interaction with the complex of replication protein A and single-stranded DNA | Q32062848 | ||
Catalysis of homologous DNA pairing by yeast Rad51 and Rad54 proteins | Q32063619 | ||
The Rad51-dependent pairing of long DNA substrates is stabilized by replication protein A. | Q32186835 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | DNA damage | Q5205747 |
cell biology | Q7141 | ||
P304 | page(s) | 99-113 | |
P577 | publication date | 2008-01-01 | |
P1433 | published in | Cell Research | Q1524018 |
P1476 | title | Homologous recombination in DNA repair and DNA damage tolerance | |
P478 | volume | 18 |
Q48048949 | A 3' untranslated region polymorphism rs2304277 in the DNA repair pathway gene OGG1 is a novel risk modulator for urothelial bladder carcinoma. |
Q40024992 | A caveat in mouse genetic engineering: ectopic gene targeting in ES cells by bidirectional extension of the homology arms of a gene replacement vector carrying human PARP-1. |
Q35072655 | A conserved sequence extending motif III of the motor domain in the Snf2-family DNA translocase Rad54 is critical for ATPase activity |
Q34085748 | A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). |
Q36165506 | A natural barrier to lateral gene transfer from prokaryotes to eukaryotes revealed from genomes: the 70 % rule |
Q37563565 | A novel role for the DNA repair gene Rad51 in Netrin-1 signalling. |
Q98471264 | A scalable CRISPR/Cas9-based fluorescent reporter assay to study DNA double-strand break repair choice |
Q34089593 | A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. |
Q35860950 | A special issue on DNA damage response and genome stability |
Q40895699 | A strand invasion 3' polymerization intermediate of mammalian homologous recombination |
Q33522877 | A truncated DNA-damage-signaling response is activated after DSB formation in the G1 phase of Saccharomyces cerevisiae |
Q34353620 | Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes |
Q37389384 | Advances in the biophysical and molecular bases of radiation cytogenetics |
Q47383621 | Akt1 Stimulates Homologous Recombination Repair of DNA Double-Strand Breaks in a Rad51-Dependent Manner |
Q64388679 | Allele-specific genome editing using CRISPR-Cas9 is associated with loss of heterozygosity in diploid yeast |
Q92633975 | Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal and Prostate Cancer |
Q33702175 | Amifostine metabolite WR-1065 disrupts homologous recombination in mammalian cells |
Q42081550 | An alternative DNA structure is necessary for pilin antigenic variation in Neisseria gonorrhoeae |
Q43165434 | Analysis of DNA-binding sites on Mhr1, a yeast mitochondrial ATP-independent homologous pairing protein |
Q37374438 | Application of RNAi-induced gene expression profiles for prognostic prediction in breast cancer |
Q89761490 | Application of a Broad Range Lytic Phage LPST94 for Biological Control of Salmonella in Foods |
Q34461047 | Archaeal replicative primases can perform translesion DNA synthesis |
Q52859096 | Assessing genotoxicity of diuron on Drosophila melanogaster by the wing-spot test and the wing imaginal disk comet assay. |
Q35209022 | AtGEN1 and AtSEND1, two paralogs in Arabidopsis, possess holliday junction resolvase activity |
Q54728311 | BCR/ABL kinase interacts with and phosphorylates the RAD51 paralog, RAD51B. |
Q53293102 | BRCA1 and BRCA2 heterozygosity in embryonic stem cells reduces radiation-induced Rad51 focus formation but is not associated with radiosensitivity. |
Q89637760 | BRCA1 and S phase DNA repair pathways restrict LINE-1 retrotransposition in human cells |
Q37507563 | BRCA1 and its toolbox for the maintenance of genome integrity |
Q28070584 | Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too? |
Q38734778 | Base Excision Repair of N6-Deoxyadenosine Adducts of 1,3-Butadiene |
Q89556013 | Biologically Aggressive Phenotype and Anti-cancer Immunity Counterbalance in Breast Cancer with High Mutation Rate |
Q42503804 | Biomarkers for genome instability in some genetic disorders: a pilot study |
Q33905610 | Blunt-ended DNA double-strand breaks induced by endonucleases PvuII and EcoRV are poor substrates for repair in Saccharomyces cerevisiae. |
Q64883202 | Build Your Own Microscope: Step-By-Step Guide for Building a Prism-Based TIRF Microscope. |
Q99614738 | Building towards Precision Oncology for Pancreatic Cancer: Real-World Challenges and Opportunities |
Q59807279 | CRISPR and Target-Specific DNA Endonucleases for Efficient DNA Knock-in in Eukaryotic Genomes |
Q57033826 | Carcinogens and DNA damage |
Q37181671 | Cdk12 is essential for embryonic development and the maintenance of genomic stability |
Q33553786 | Cellular redistribution of Rad51 in response to DNA damage: novel role for Rad51C. |
Q37600456 | Chapter 6. Application of new methods for detection of DNA damage and repair |
Q28395425 | Characterization and comparative genomic analysis of a novel bacteriophage, SFP10, simultaneously inhibiting both Salmonella enterica and Escherichia coli O157:H7 |
Q35878757 | Characterization of a highly conserved histone related protein, Ydl156w, and its functional associations using quantitative proteomic analyses |
Q42197242 | Characterization of the morphology and genome of an Escherichia coli podovirus |
Q41816072 | Checkpoints are blind to replication restart and recombination intermediates that result in gross chromosomal rearrangements. |
Q34849073 | Chemical inhibitor targeting the replication protein A-DNA interaction increases the efficacy of Pt-based chemotherapy in lung and ovarian cancer |
Q28066464 | Choices have consequences: the nexus between DNA repair pathways and genomic instability in cancer |
Q88661083 | Clinically Applicable Inhibitors Impacting Genome Stability |
Q33798999 | Combination Platinum-based and DNA Damage Response-targeting Cancer Therapy: Evolution and Future Directions |
Q99615015 | Comparative Study of the Mode of Action of Clinically Approved Platinum-Based Chemotherapeutics |
Q30551528 | Contributions of the RAD51 N-terminal domain to BRCA2-RAD51 interaction. |
Q34723611 | Cooperation of RAD51 and RAD54 in regression of a model replication fork |
Q39443939 | Corrupting the DNA damage response: a critical role for Rad52 in tumor cell survival |
Q36102439 | Critical interaction domains between bloom syndrome protein and RAD51 |
Q26778614 | Cross talk of tyrosine kinases with the DNA damage signaling pathways |
Q27650328 | Crystal structure of the Mus81-Eme1 complex |
Q52320296 | Crystal structure of the novel lesion-specific endonuclease PfuEndoQ from Pyrococcus furiosus. |
Q27665450 | Crystal structure of the phage T4 recombinase UvsX and its functional interaction with the T4 SF2 helicase UvsW |
Q60909331 | DNA Damage Tolerance Mechanisms Revealed from the Analysis of Immunoglobulin V Gene Diversification in Avian DT40 Cells |
Q37056627 | DNA damage checkpoint and recombinational repair differentially affect the replication stress tolerance of Smc6 mutants |
Q37627226 | DNA double-strand break repair genotype and phenotype and breast cancer risk within sisters from the New York site of the Breast Cancer Family Registry (BCFR). |
Q34525913 | DNA double-strand break repair in Caenorhabditis elegans |
Q36394254 | DNA polymerases δ and λ cooperate in repairing double-strand breaks by microhomology-mediated end-joining in Saccharomyces cerevisiae |
Q26745476 | DNA repair by RNA: Templated, or not templated, that is the question |
Q34980859 | DNA-PKcs inhibition sensitizes cancer cells to carbon-ion irradiation via telomere capping disruption |
Q47360892 | Data on Single Nucleotide Polymorphism of DNA Repair Genes and Breast Cancer Risk from Poland |
Q38695071 | Decision for cell fate: deubiquitinating enzymes in cell cycle checkpoint |
Q41891208 | Defining the roles of the N-terminal region and the helicase activity of RECQ4A in DNA repair and homologous recombination in Arabidopsis |
Q92051220 | Depletion of Akt1 and Akt2 Impairs the Repair of Radiation-Induced DNA Double Strand Breaks via Homologous Recombination |
Q42199897 | Depletion of Werner helicase results in mitotic hyperrecombination and pleiotropic homologous and nonhomologous recombination phenotypes |
Q90411820 | Designing an Engineered Construct Gene Sensitive to Carbohydrate In-vitro and Candidate for Human Insulin Gene Therapy In-vivo |
Q50731211 | Developmental and oncogenic radiation effects on neural stem cells and their differentiating progeny in mouse cerebellum. |
Q27694684 | Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns |
Q24307674 | Discovery of a novel function for human Rad51: maintenance of the mitochondrial genome |
Q38163013 | Discussion of PARP inhibitors in cancer therapy |
Q33628502 | Double-strand break repair pathways protect against CAG/CTG repeat expansions, contractions and repeat-mediated chromosomal fragility in Saccharomyces cerevisiae |
Q24313650 | Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination |
Q33628866 | Dual roles for DNA polymerase theta in alternative end-joining repair of double-strand breaks in Drosophila |
Q36228483 | Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation |
Q51766662 | Dynamic mRNA and miRNA profiling of CHO-K1 suspension cell cultures. |
Q36878102 | Effect of EME1 exon variant Ile350Thr on risk and early onset of breast cancer in southern Chinese women |
Q64389625 | Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells |
Q50893120 | Enhanced genome editing in mammalian cells with a modified dual-fluorescent surrogate system. |
Q35182121 | Epistasis analysis between homologous recombination genes in Saccharomyces cerevisiae identifies multiple repair pathways for Sgs1, Mus81-Mms4 and RNase H2 |
Q35823927 | Evaluation of DNA double strand breaks repair efficiency in head and neck cancer |
Q59803444 | Evolutionary diversity and novelty of DNA repair genes in asexual Bdelloid rotifers |
Q33514111 | Evolutionary relationships among salivarius streptococci as inferred from multilocus phylogenies based on 16S rRNA-encoding, recA, secA, and secY gene sequences |
Q41352646 | Expression of cancer related BRCA1 missense variants decreases MMS-induced recombination in Saccharomyces cerevisiae without altering its nuclear localization |
Q49836879 | Expression, Purification, and Biochemical Evaluation of Human RAD51 Protein. |
Q34568206 | FANC pathway promotes UV-induced stalled replication forks recovery by acting both upstream and downstream Polη and Rev1. |
Q39847548 | FANCD2-deficient human fibroblasts are hypersensitive to ionising radiation at oxygen concentrations of 0% and 3% but not under normoxic conditions |
Q37391123 | FANCJ helicase operates in the Fanconi Anemia DNA repair pathway and the response to replicational stress |
Q34313139 | FBXL5-mediated degradation of single-stranded DNA-binding protein hSSB1 controls DNA damage response |
Q28588718 | Functional characterization and identification of mouse Rad51d splice variants |
Q34305789 | Functions of FUS/TLS from DNA repair to stress response: implications for ALS. |
Q35209502 | Functions of the Snf2/Swi2 family Rad54 motor protein in homologous recombination |
Q91938470 | Gene Therapy Tools for Brain Diseases |
Q37552793 | Gene targeting from laboratory to livestock: current status and emerging concepts. |
Q43240675 | Genetic evidence for a role of Saccharomyces cerevisiae Mph1 in recombinational DNA repair under replicative stress |
Q36177874 | Genetic polymorphisms in homologous recombination repair genes in healthy Slovenian population and their influence on DNA damage |
Q40106664 | Genetic recombinational events in prokaryotes and their viruses: insight into the study of evolution and biodiversity |
Q36085389 | Genetic variability of DNA repair mechanisms influences treatment outcome of gastric cancer |
Q36045134 | Genetic variants at 14q24.1 and breast cancer susceptibility: a fine-mapping study in Chinese women |
Q34755147 | Genomic DNA damage and ATR-Chk1 signaling determine oncolytic adenoviral efficacy in human ovarian cancer cells. |
Q38735426 | Genomic instability in pancreatic adenocarcinoma: a new step towards precision medicine and novel therapeutic approaches. |
Q39957898 | Germline Chromothripsis Driven by L1-Mediated Retrotransposition and Alu/Alu Homologous Recombination |
Q92410933 | Germline and Somatic Defects in DNA Repair Pathways in Prostate Cancer |
Q100738000 | Germline testing for homologous recombination repair genes - opportunities and challenges |
Q30449815 | Heavy ions, radioprotectors and genomic instability: implications for human space exploration |
Q57477219 | High fidelity CRISPR/Cas9 increases precise monoallelic and biallelic editing events in primordial germ cells |
Q37041218 | Homologous Recombination Repair Polymorphisms and the Risk for Osteosarcoma |
Q91808014 | Homologous Recombination under the Single-Molecule Fluorescence Microscope |
Q96022696 | Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer |
Q37447887 | Homologous recombination but not nucleotide excision repair plays a pivotal role in tolerance of DNA-protein cross-links in mammalian cells |
Q58801181 | Homologous recombination deficiency in ovarian cancer: a review of its epidemiology and management |
Q41849802 | Homologous recombination in budding yeast expressing the human RAD52 gene reveals a Rad51-independent mechanism of conservative double-strand break repair |
Q52695881 | How oxygen gave rise to eukaryotic sex. |
Q24337537 | Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions |
Q38874111 | Human Induced Pluripotent Stem Cells as a Platform for Personalized and Precision Cardiovascular Medicine. |
Q35097955 | Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins. |
Q34440697 | Human PrimPol mutation associated with high myopia has a DNA replication defect |
Q34218130 | Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair. |
Q42143700 | In vitro assays for DNA pairing and recombination-associated DNA synthesis |
Q34363341 | In vivo bypass of 8-oxodG. |
Q37740915 | Inching over hurdles: how DNA helicases move on crowded lattices |
Q37123923 | Increased Fanconi C expression contributes to the emergency granulopoiesis response |
Q41135252 | Increased sensitivity to ionizing radiation by targeting the homologous recombination pathway in glioma initiating cells. |
Q37984197 | Inhibiting homologous recombination for cancer therapy |
Q36579532 | Inositol pyrophosphate synthesis by inositol hexakisphosphate kinase 1 is required for homologous recombination repair |
Q38064778 | Integration of DNA damage and repair with murine double-minute 2 (Mdm2) in tumorigenesis |
Q34280451 | Involvement of a chromatin remodeling complex in damage tolerance during DNA replication |
Q24649491 | Involvement of nucleotide excision and mismatch repair mechanisms in double strand break repair |
Q34538670 | JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks. |
Q21563320 | Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells |
Q28119017 | Ku86 represses lethal telomere deletion events in human somatic cells |
Q52430423 | Ligase IV inhibitor SCR7 enhances gene editing directed by CRISPR-Cas9 and ssODN in human cancer cells. |
Q36118895 | Loss of heterozygosity for chromosomal regions 15q14-21.1, 17q21.31, and 13q12.3-13.1 and its relevance for prostate cancer |
Q39576714 | MET inhibition in tumor cells by PHA665752 impairs homologous recombination repair of DNA double strand breaks |
Q37181568 | MRE11 complex links RECQ5 helicase to sites of DNA damage |
Q37622790 | MRN and the race to the break |
Q98280991 | Maintenance of genome integrity and active homologous recombination in embryonic stem cells |
Q37807127 | Making the best of the loose ends: Mre11/Rad50 complexes and Sae2 promote DNA double-strand break resection |
Q64387955 | Mapping global and local coevolution across 600 species to identify novel homologous recombination repair genes |
Q35917385 | Mating-type genes and MAT switching in Saccharomyces cerevisiae |
Q39293345 | Mechanisms of DNA damage, repair, and mutagenesis |
Q41366654 | Microarray analysis of differentially expressed genes in ovarian and fallopian tube epithelium from risk-reducing salpingo-oophorectomies. |
Q35164333 | Mismatch repair during homologous and homeologous recombination |
Q90266838 | Misrepair in Context: TGFβ Regulation of DNA Repair |
Q93333875 | Molecular Pathogenesis of Low-Grade Glioma |
Q33759106 | Molecular basis for PrimPol recruitment to replication forks by RPA |
Q64097188 | Molecular mechanisms in progression of HPV-associated cervical carcinogenesis |
Q28070323 | Molecular mechanisms of HPV mediated neoplastic progression |
Q46688275 | Multi-BRCT Domain Protein Brc1 Links Rhp18/Rad18 and γH2A To Maintain Genome Stability during S Phase |
Q58695632 | Mutagenic assessment of chemotherapy and Smac mimetic drugs in cells with defective DNA damage response pathways |
Q42684913 | Mutational analysis of Brh2 reveals requirements for compensating mediator functions |
Q34657712 | Mystery of DNA repair: the role of the MRN complex and ATM kinase in DNA damage repair |
Q33842009 | Nanobiomotors of archaeal DNA repair machineries: current research status and application potential |
Q39019557 | Nascent DNA synthesis during homologous recombination is synergistically promoted by the rad51 recombinase and DNA homology |
Q57491394 | Network Analysis of RAD51 Proteins in Metazoa and the Evolutionary Relationships With Their Archaeal Homologs |
Q38789155 | New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress |
Q90224455 | Nickel Carcinogenesis Mechanism: DNA Damage |
Q37021526 | Nonsense-mediated decay regulates key components of homologous recombination |
Q37302669 | Novel insights into RAD51 activity and regulation during homologous recombination and DNA replication |
Q38220992 | Nuclease delivery: versatile functions of SLX4/FANCP in genome maintenance |
Q26822478 | Nucleases in homologous recombination as targets for cancer therapy |
Q36288503 | O6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas |
Q49836867 | Observation and Analysis of RAD51 Nucleation Dynamics at Single-Monomer Resolution. |
Q28307657 | Oligo/polynucleotide-based gene modification: strategies and therapeutic potential |
Q54588181 | Opposite modifying effects of HR and NHEJ deficiency on cancer risk in Ptc1 heterozygous mouse cerebellum. |
Q37194752 | Oxidative damage and mutagenesis in Saccharomyces cerevisiae: genetic studies of pathways affecting replication fidelity of 8-oxoguanine |
Q47131342 | PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection |
Q30921143 | PCNA is required for initiation of recombination-associated DNA synthesis by DNA polymerase delta |
Q97540196 | Pamiparib is a potent and selective PARP inhibitor with unique potential for the treatment of brain tumor |
Q42793326 | Pathways for Holliday junction processing during homologous recombination in Saccharomyces cerevisiae. |
Q40801597 | Pathways for double-strand break repair in genetically unstable Z-DNA-forming sequences |
Q38223676 | Pathways for genome integrity in G2 phase of the cell cycle |
Q41857124 | Peptide aptamer mimicking RAD51-binding domain of BRCA2 inhibits DNA damage repair and survival in Trypanosoma brucei |
Q47205384 | Photosynthetic functions of Synechococcus in the ocean microbiomes of diverse salinity and seasons |
Q91802196 | Platinum Salts in Patients with Breast Cancer: A Focus on Predictive Factors |
Q40404211 | PolDIP2 interacts with human PrimPol and enhances its DNA polymerase activities. |
Q64387964 | Polymorphism of DNA Repair Genes via Homologous Recombination (HR) in Ovarian Cancer |
Q36936978 | Preferential D-loop extension by a translesion DNA polymerase underlies error-prone recombination |
Q24308876 | PrimPol bypasses UV photoproducts during eukaryotic chromosomal DNA replication |
Q38866687 | PrimPol-A new polymerase on the block |
Q34025948 | Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes |
Q37613647 | Programmable Genome Editing Tools and their Regulation for Efficient Genome Engineering |
Q30450792 | Purification of FANCD2 sub-complexes |
Q40997100 | RAD51 haploinsufficiency causes congenital mirror movements in humans |
Q37800769 | RAD51C: a novel cancer susceptibility gene is linked to Fanconi anemia and breast cancer |
Q42635196 | RDM1 gene overexpression represents a therapeutic target in papillary thyroid carcinoma. |
Q40988187 | REPLACR-mutagenesis, a one-step method for site-directed mutagenesis by recombineering |
Q39167940 | RNAi silencing targeting RNF8 enhances radiosensitivity of a non-small cell lung cancer cell line A549. |
Q24309568 | RTEL1 maintains genomic stability by suppressing homologous recombination |
Q36097164 | Rad51 Expression in Nasopharyngeal Carcinoma and Its Association with Tumor Reduction: A Preliminary Study in Indonesia |
Q34071842 | Rad51 and BRCA2--New molecular targets for sensitizing glioma cells to alkylating anticancer drugs |
Q39503969 | Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death. |
Q34058338 | Rad52 SUMOylation affects the efficiency of the DNA repair |
Q33652233 | Rad52/Rad59-dependent recombination as a means to rectify faulty Okazaki fragment processing. |
Q41607544 | Rad54 is not essential for any geminiviral replication mode in planta |
Q93035884 | Radiation resistance of normal human astrocytes: the role of non-homologous end joining DNA repair activity |
Q33792899 | Radiation-generated short DNA fragments may perturb non-homologous end-joining and induce genomic instability |
Q33900056 | RecA maintains the integrity of chloroplast DNA molecules in Arabidopsis |
Q30366224 | RecO protein initiates DNA recombination and strand annealing through two alternative DNA binding mechanisms. |
Q37166694 | Recognition of double strand breaks by a mutator protein (MU2) in Drosophila melanogaster |
Q37254288 | Recombination-dependent oligomerization of human papillomavirus genomes upon transient DNA replication |
Q52723083 | Recruitment kinetics of the homologous recombination pathway in procyclic forms of Trypanosoma brucei after ionizing radiation treatment. |
Q34516867 | Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition |
Q92709516 | Regulation of gene expression by altered promoter methylation using a CRISPR/Cas9-mediated epigenetic editing system |
Q33966065 | Regulation of homologous recombination in eukaryotes |
Q38559892 | Regulation of recombination and genomic maintenance |
Q36879506 | Regulation of therapeutic resistance in cancers by receptor tyrosine kinases |
Q35200273 | Regulators of homologous recombination repair as novel targets for cancer treatment. |
Q28755375 | RepPop: a database for repetitive elements in Populus trichocarpa |
Q37775586 | Repair of DNA interstrand cross-links during S phase of the mammalian cell cycle |
Q37346254 | Repair of DNA lesions associated with triplex-forming oligonucleotides |
Q39969993 | Repair of I-SceI induced DSB at a specific site of chromosome in human cells: influence of low-dose, low-dose-rate gamma-rays |
Q37938603 | Repairing split ends: SIRT6, mono-ADP ribosylation and DNA repair. |
Q37993652 | Replication fork dynamics and the DNA damage response. |
Q33509264 | Replication protein A (RPA1a) is required for meiotic and somatic DNA repair but is dispensable for DNA replication and homologous recombination in rice |
Q38768243 | Repriming by PrimPol is critical for DNA replication restart downstream of lesions and chain-terminating nucleosides |
Q48162485 | Revolutionizing male fertility factor research in mice by using the genome editing tool CRISPR/Cas9. |
Q61799067 | Robust and efficient knock-in in embryonic stem cells and early-stage embryos of the common marmoset using the CRISPR-Cas9 system |
Q37775588 | Role of homologous recombination in DNA interstrand crosslink repair |
Q35069570 | Role of lamin b1 in chromatin instability |
Q53687949 | Role of long non-coding RNA in drug resistance in non-small cell lung cancer. |
Q24646853 | Roles of RECQ helicases in recombination based DNA repair, genomic stability and aging |
Q38048886 | Sequence and structural basis for chromosomal fragility during translocations in cancer |
Q49354543 | Single-molecule live-cell imaging of bacterial DNA repair and damage tolerance. |
Q35841330 | Single-nucleotide polymorphisms in DNA bypass polymerase genes and association with breast cancer and breast cancer subtypes among African Americans and Whites. |
Q35835383 | Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers. |
Q37171001 | Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cells |
Q34339095 | Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage |
Q35764178 | Spindle Checkpoint Factors Bub1 and Bub2 Promote DNA Double-Strand Break Repair by Nonhomologous End Joining |
Q27938895 | Srs2 disassembles Rad51 filaments by a protein-protein interaction triggering ATP turnover and dissociation of Rad51 from DNA. |
Q34517593 | Structural and functional insights from the metagenome of an acidic hot spring microbial planktonic community in the Colombian Andes. |
Q35961942 | Structural basis for substrate recognition and processive cleavage mechanisms of the trimeric exonuclease PhoExo I. |
Q46237274 | Studies of lncRNAs in DNA double strand break repair: what is new? |
Q38630696 | Sunitinib induces genomic instability of renal carcinoma cells through affecting the interaction of LC3-II and PARP-1. |
Q37226478 | Synthetic genetic targeting of genome instability in cancer. |
Q34671726 | Synthetic lethality between gene defects affecting a single non-essential molecular pathway with reversible steps |
Q64077863 | TLP-mediated global transcriptional repression after double-strand DNA breaks slows down DNA repair and induces apoptosis |
Q35731289 | TODRA, a lncRNA at the RAD51 Locus, Is Oppositely Regulated to RAD51, and Enhances RAD51-Dependent DSB (Double Strand Break) Repair |
Q50088140 | TP53 Haploinsufficiency Rescues Emergency Granulopoiesis in FANCC-/- Mice. |
Q64058293 | Tailoring Ovarian Cancer Treatment: Implications of Mutations |
Q35757980 | Targeted inhibition of histone deacetylases and hedgehog signaling suppress tumor growth and homologous recombination in aerodigestive cancers. |
Q47308626 | Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy |
Q39383614 | Targeting PI3K and RAD51 in Barrett's adenocarcinoma: impact on DNA damage checkpoints, expression profile and tumor growth |
Q37019392 | Targeting cancer with a lupus autoantibody |
Q37769804 | Targeting inflammatory pathways for tumor radiosensitization. |
Q38651063 | The Association of Low-Penetrance Variants in DNA Repair Genes with Colorectal Cancer: A Systematic Review and Meta-Analysis |
Q37272458 | The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single- versus double-stranded DNA to stimulate strand exchange |
Q38821634 | The Changing Landscape of Genetic Testing for Inherited Breast Cancer Predisposition |
Q60922544 | The DNA damage response is developmentally regulated in the African trypanosome |
Q54209627 | The HTLV-1 basic leucine zipper factor (HBZ) attenuates repair of double-stranded DNA breaks via non-homologous end joining (NHEJ). |
Q37526483 | The MRE11 complex: starting from the ends. |
Q24616365 | The Role of PCNA Posttranslational Modifications in Translesion Synthesis |
Q33948571 | The Smc5/6 complex and Esc2 influence multiple replication-associated recombination processes in Saccharomyces cerevisiae |
Q95839849 | The bromodomain containing protein BRD-9 orchestrates RAD51-RAD54 complex formation and regulates homologous recombination-mediated repair |
Q39835877 | The carboxyl terminus of Brca2 links the disassembly of Rad51 complexes to mitotic entry |
Q28115800 | The catalytic subunit of DNA-dependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cells |
Q33720883 | The cohesin-like RecN protein stimulates RecA-mediated recombinational repair of DNA double-strand breaks. |
Q90645627 | The correction of ETV6/RUNX1 translocation in acute lymphocytic leukemia cells: a new gene targeting system by homologous recombination mechanism |
Q92214210 | The current state of molecular testing in the treatment of patients with solid tumors, 2019 |
Q39179722 | The enigmatic oncogene and tumor suppressor-like properties of RAD54B: Insights into genome instability and cancer |
Q53775795 | The functional status of DNA repair pathways determines the sensitization effect to cisplatin in non-small cell lung cancer cells. |
Q24599645 | The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells |
Q38233068 | The potential of PARP inhibitors in neuro-oncology |
Q28272384 | The rice RAD51C gene is required for the meiosis of both female and male gametocytes and the DNA repair of somatic cells |
Q38064172 | The role of BRCA1 in DNA double-strand repair: past and present |
Q37781516 | The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers |
Q35113821 | Top3-Rmi1 dissolve Rad51-mediated D loops by a topoisomerase-based mechanism |
Q37174956 | Triapine potentiates platinum-based combination therapy by disruption of homologous recombination repair |
Q39781851 | Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase. |
Q36145592 | Tyrosine phosphorylation stimulates activity of human RAD51 recombinase through altered nucleoprotein filament dynamics |
Q54231304 | Unveiling benznidazole's mechanism of action through overexpression of DNA repair proteins in Trypanosoma cruzi. |
Q64254541 | Women's cancers: how the discovery of BRCA genes is driving current concepts of cancer biology and therapeutics |
Q95728259 | XRCC4 c.1394G>T Single Nucleotide Polymorphisms and Breast Cancer Risk among Filipinos |
Q35031979 | YAP regulates S-phase entry in endothelial cells |
Q38858838 | hCAS/CSE1L regulates RAD51 distribution and focus formation for homologous recombinational repair |
Q36228025 | mRNA and DNA selection via protein multimerization: YB-1 as a case study. |
Q36874139 | mTOR Inhibitors Suppress Homologous Recombination Repair and Synergize with PARP Inhibitors via Regulating SUV39H1 in BRCA-Proficient Triple-Negative Breast Cancer |
Q36394957 | tRNA processing defects induce replication stress and Chk2-dependent disruption of piRNA transcription. |
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