Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A

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Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1032938454
P356DOI10.1038/34950
P3181OpenCitations bibliographic resource ID359749
P698PubMed publication ID9450760
P5875ResearchGate publication ID13779490

P2093author name stringS C Kowalczykowski
T Sugiyama
E Zaitseva
J H New
P2860cites workPhysical interaction between human RAD52 and RPA is required for homologous recombination in mammalian cellsQ24311394
A novel allele of Saccharomyces cerevisiae RFA1 that is deficient in recombination and repair and suppressible by RAD52.Q27933094
Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like proteinQ27933995
Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 proteinQ27937922
Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinaseQ27938070
Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolismQ28245231
A single-stranded DNA-binding protein is needed for efficient presynaptic complex formation by the Saccharomyces cerevisiae Rad51 proteinQ28647553
Function of yeast Rad52 protein as a mediator between replication protein A and the Rad51 recombinaseQ29620205
DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that of RecAQ29622863
A mutation in the gene encoding the Saccharomyces cerevisiae single-stranded DNA-binding protein Rfa1 stimulates a RAD52-independent pathway for direct-repeat recombinationQ36550036
DNA strand annealing is promoted by the yeast Rad52 proteinQ37293228
A Rad52 homolog is required for RAD51-independent mitotic recombination in Saccharomyces cerevisiaeQ38354045
Homologous pairing and DNA strand-exchange proteins.Q45944296
Dominant negative alleles of RAD52 reveal a DNA repair/recombination complex including Rad51 and Rad52.Q48103110
Effects of Escherichia coli SSB protein on the single-stranded DNA-dependent ATPase activity of Escherichia coli RecA protein. Evidence that SSB protein facilitates the binding of RecA protein to regions of secondary structure within single-strandedQ54768170
Yeast Rad51 recombinase mediates polar DNA strand exchange in the absence of ATP hydrolysisQ71763096
DNA structure-dependent requirements for yeast RAD genes in gene conversionQ72356626
P433issue6665
P407language of work or nameEnglishQ1860
P304page(s)407-10
P577publication date1998-01-22
P1433published inNatureQ180445
P1476titleRad52 protein stimulates DNA strand exchange by Rad51 and replication protein A
P478volume391

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cites work (P2860)
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Q44712199Effect of expression of the Escherichia coli nth gene in Saccharomyces cerevisiae on the toxicity of ionizing radiation and hydrogen peroxide
Q40799711Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group.
Q57557305Elevated expression of exogenous Rad51 leads to identical increases in gene-targeting frequency in murine embryonic stem (ES) cells with both functional and dysfunctional p53 genes
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Q30870765Escherichia coli RecO protein anneals ssDNA complexed with its cognate ssDNA-binding protein: A common step in genetic recombination
Q59797152Fanconi Anaemia-Like Mph1 Helicase Backs up Rad54 and Rad5 to Circumvent Replication Stress-Driven Chromosome Bridges
Q39709472Fission yeast Swi5-Sfr1 protein complex, an activator of Rad51 recombinase, forms an extremely elongated dogleg-shaped structure
Q36963162Focus on histone variant H2AX: to be or not to be.
Q58988714From competition to collaboration
Q28389638From yeast to mammals: recent advances in genetic control of homologous recombination
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Q35911023Functional analysis of maize RAD51 in meiosis and double-strand break repair
Q30411134Functional and structural basis for a bacteriophage homolog of human RAD52.
Q33180095Functional interactions among yeast Rad51 recombinase, Rad52 mediator, and replication protein A in DNA strand exchange
Q33559432GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination
Q35088993Gain- and loss-of-function of Rhp51, a Rad51 homolog in fission yeast, reveals dissimilarities in chromosome integrity
Q64955796Gene Expression Noise Produces Cell-to-Cell Heterogeneity in Eukaryotic Homologous Recombination Rate.
Q34001661Genetic analysis of homologous DNA recombination in vertebrate somatic cells
Q28579624Genetic evidence suggests that Spata22 is required for the maintenance of Rad51 foci in mammalian meiosis
Q25255793Genome wide distribution of illegitimate recombination events in Kluyveromyces lactis
Q27929891Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination
Q47108896Genome-wide mapping of sister chromatid exchange events in single yeast cells using Strand-seq
Q28768558Genomic fossils as a snapshot of the human transcriptome
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Q43874869Gly-103 in the N-terminal domain of Saccharomyces cerevisiae Rad51 protein is critical for DNA binding
Q30857859Heteroduplex joint formation by a stoichiometric complex of Rad51 and Rad52 of Saccharomyces cerevisiae
Q90065014Histone H4 dosage modulates DNA damage response in the pathogenic yeast Candida glabrata via homologous recombination pathway
Q34311675Homologous DNA recombination in vertebrate cells
Q35008336Homologous and non-homologous recombination differentially affect DNA damage repair in mice
Q49236959Homologous pairing promoted by the human Rad52 protein.
Q57753680Homologous recombination and the repair of DNA double-strand breaks
Q24601150Homologous recombination in DNA repair and DNA damage tolerance
Q39576472Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52.
Q24542520Homologous recombination: from model organisms to human disease
Q33433812Homologous recombinational repair factors are recruited and loaded onto the viral DNA genome in Epstein-Barr virus replication compartments
Q64388187Human RAD52 exhibits two modes of self-association
Q36383522Human RAD52 interactions with replication protein A and the RAD51 presynaptic complex
Q33398697Human Rad51 mediated DNA unwinding is facilitated by conditions that favour Rad51-dsDNA aggregation
Q38329710Human Rad51 protein can form homologous joints in the absence of net strand exchange
Q33524756Human Rad52 binds and wraps single-stranded DNA and mediates annealing via two hRad52-ssDNA complexes
Q33468536Human replication protein A-Rad52-single-stranded DNA complex: stoichiometry and evidence for strand transfer regulation by phosphorylation
Q36027589Human single-stranded DNA binding proteins: guardians of genome stability
Q38761267Human somatic cells deficient for RAD52 are impaired for viral integration and compromised for most aspects of homology-directed repair
Q24292055Identification and purification of two distinct complexes containing the five RAD51 paralogs
Q24322577Identification of a novel human Rad51 variant that promotes DNA strand exchange
Q35676652Identification of a second DNA binding site in the human Rad52 protein
Q39895156Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi
Q42143700In vitro assays for DNA pairing and recombination-associated DNA synthesis
Q93162093In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation
Q27939283In vivo assembly and disassembly of Rad51 and Rad52 complexes during double-strand break repair
Q27930596In vivo roles of Rad52, Rad54, and Rad55 proteins in Rad51-mediated recombination.
Q27660441Insights into the mechanism of Rad51 recombinase from the structure and properties of a filament interface mutant
Q38064778Integration of DNA damage and repair with murine double-minute 2 (Mdm2) in tumorigenesis
Q24292684Interaction between BRCA2 and replication protein A is compromised by a cancer-predisposing mutation in BRCA2
Q24548334Interaction of human rad51 recombination protein with single-stranded DNA binding protein, RPA
Q89505485Interaction of yeast Rad51 and Rad52 relieves Rad52-mediated inhibition of de novo telomere addition
Q33360205Interaction with RPA is necessary for Rad52 repair center formation and for its mediator activity
Q44097432Interaction with Rad51 is indispensable for recombination mediator function of Rad52.
Q30638467Involvement of DNA-dependent protein kinase in UV-induced replication arrest
Q24292292Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells
Q42078533Involvement of Schizosaccharomyces pombe rrp1+ and rrp2+ in the Srs2- and Swi5/Sfr1-dependent pathway in response to DNA damage and replication inhibition
Q33885431Links between replication, recombination and genome instability in eukaryotes
Q42611090Localization and dynamic relocalization of mammalian Rad52 during the cell cycle and in response to DNA damage
Q27934351Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo
Q34930681Long CTG Tracts from the Myotonic Dystrophy Gene Induce Deletions and Rearrangements during Recombination at the APRT Locus in CHO Cells
Q30439975Loop 2 in Saccharomyces cerevisiae Rad51 protein regulates filament formation and ATPase activity
Q34864784Mammalian 5' C-rich telomeric overhangs are a mark of recombination-dependent telomere maintenance
Q26782193Managing Single-Stranded DNA during Replication Stress in Fission Yeast
Q34311686Manipulating the mammalian genome by homologous recombination
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Q28608973Mechanisms of human DNA repair: an update
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Q38258736Mediators of homologous DNA pairing
Q35543795Mending the Break: Two DNA Double-Strand Break Repair Machines in Eukaryotes
Q27930745Mgm101 is a Rad52-related protein required for mitochondrial DNA recombination
Q47142346MiR-302a sensitizes leukemia cells to etoposide by targeting Rad52.
Q40547188MiRNA-binding site functional polymorphisms in DNA repair genes RAD51, RAD52, and XRCC2 and breast cancer risk in Chinese population
Q35164333Mismatch repair during homologous and homeologous recombination
Q33321813Molecular anatomy of the recombination mediator function of Saccharomyces cerevisiae Rad52.
Q58306306Molecular cloning and characterization of arecA‐like gene induced by DNA damage from a fluorescentPseudomonassp
Q38305014Molecular dissection of interactions between Rad51 and members of the recombination-repair group
Q33704559Molecular interaction map of the mammalian cell cycle control and DNA repair systems
Q34484541Molecular mechanisms of DNA double strand break repair
Q34306334Molecular pathways: understanding the role of Rad52 in homologous recombination for therapeutic advancement
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Q27674627Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair
Q36080100Multiple Rad52-Mediated Homology-Directed Repair Mechanisms Are Required to Prevent Telomere Attrition-Induced Senescence in Saccharomyces cerevisiae
Q28354223Multiple interactions among the components of the recombinational DNA repair system in Schizosaccharomyces pombe
Q24548535Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
Q35233502Multiple regulation of Rad51-mediated homologous recombination by fission yeast Fbh1.
Q42684913Mutational analysis of Brh2 reveals requirements for compensating mediator functions
Q52651787Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.
Q31078342Mutations in yeast Rad51 that partially bypass the requirement for Rad55 and Rad57 in DNA repair by increasing the stability of Rad51-DNA complexes
Q24316509N terminus of CtIP is critical for homologous recombination-mediated double-strand break repair
Q46131370NADH-coupled microplate photometric assay for kinetic studies of ATP-hydrolyzing enzymes with low and high specific activities
Q37021526Nonsense-mediated decay regulates key components of homologous recombination
Q64280942Novel RNA and DNA strand exchange activity of the PALB2 DNA binding domain and its critical role for DNA repair in cells
Q34669076Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation
Q36835707PCNA is efficiently loaded on the DNA recombination intermediate to modulate polymerase δ, η, and ζ activities.
Q33834760Pathways to meiotic recombination in Arabidopsis thaliana
Q35202862Pds1 and Esp1 control both anaphase and mitotic exit in normal cells and after DNA damage.
Q39126666Phosphorylation of Rad55 on serines 2, 8, and 14 is required for efficient homologous recombination in the recovery of stalled replication forks
Q24305521Physical and functional interaction between the XPF/ERCC1 endonuclease and hRad52
Q33200674Physical interaction between replication protein A and Rad51 promotes exchange on single-stranded DNA.
Q24813430Potentiation of gene targeting in human cells by expression of Saccharomyces cerevisiae Rad52
Q24630609Precise binding of single-stranded DNA termini by human RAD52 protein
Q42252789Presynaptic filament dynamics in homologous recombination and DNA repair
Q34307988Protein dynamics during presynaptic-complex assembly on individual single-stranded DNA molecules
Q37150956Proteins involved in meiotic recombination: a role in male infertility?
Q64388437Purification and assays of Saccharomyces cerevisiae homologous recombination proteins
Q24297031Purified human BRCA2 stimulates RAD51-mediated recombination
Q92932218Putting together and taking apart: assembly and disassembly of the Rad51 nucleoprotein filament in DNA repair and genome stability
Q24554318RAD51 is required for the repair of plasmid double-stranded DNA gaps from either plasmid or chromosomal templates
Q34709121RAD51-independent inverted-repeat recombination by a strand-annealing mechanism
Q37800769RAD51C: a novel cancer susceptibility gene is linked to Fanconi anemia and breast cancer
Q28274789RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination
Q56896449RMPs: recombination/replication mediator proteins
Q34537165RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycle
Q34740136RPA coordinates DNA end resection and prevents formation of DNA hairpins
Q24338859RPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cells
Q38630544RSC facilitates Rad59-dependent homologous recombination between sister chromatids by promoting cohesin loading at DNA double-strand breaks.
Q37341165Rad1, rad10 and rad52 mutations reduce the increase of microhomology length during radiation-induced microhomology-mediated illegitimate recombination in saccharomyces cerevisiae
Q34385513Rad51 ATP binding but not hydrolysis is required to recruit Rad10 in synthesis-dependent strand annealing sites in S. cerevisiae
Q30444605Rad51 and Rad54 ATPase activities are both required to modulate Rad51-dsDNA filament dynamics
Q37507641Rad51 and Rad54 promote noncrossover recombination between centromere repeats on the same chromatid to prevent isochromosome formation
Q33649800Rad51 inhibits translocation formation by non-conservative homologous recombination in Saccharomyces cerevisiae
Q33323517Rad51 protein controls Rad52-mediated DNA annealing
Q28611350Rad51/RecA protein families and the associated proteins in eukaryotes
Q90201472Rad52 Restrains Resection at DNA Double-Strand Break Ends in Yeast
Q39922609Rad52 and Ku bind to different DNA structures produced early in double-strand break repair
Q27931495Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes
Q27929749Rad52 forms DNA repair and recombination centers during S phase
Q27930553Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing
Q28300346Rad52 inactivation is synthetically lethal with BRCA2 deficiency
Q43091924Rad52 multimerization is important for its nuclear localization in Saccharomyces cerevisiae
Q30453366Rad52 partially substitutes for the Rad51 paralog XRCC3 in maintaining chromosomal integrity in vertebrate cells
Q64104226Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
Q27932985Rad52 promotes postinvasion steps of meiotic double-strand-break repair
Q33407137Rad52 promotes second-end DNA capture in double-stranded break repair to form complement-stabilized joint molecules
Q30736645Rad52 protein associates with replication protein A (RPA)-single-stranded DNA to accelerate Rad51-mediated displacement of RPA and presynaptic complex formation
Q31053009Rad52 protein has a second stimulatory role in DNA strand exchange that complements replication protein-A function
Q28534315Rad52 sumoylation prevents the toxicity of unproductive Rad51 filaments independently of the anti-recombinase Srs2
Q33263102Rad52-mediated DNA annealing after Rad51-mediated DNA strand exchange promotes second ssDNA capture
Q45955638Rad54 protein exerts diverse modes of ATPase activity on duplex DNA partially and fully covered with Rad51 protein.
Q46189017Rad54 protein is targeted to pairing loci by the Rad51 nucleoprotein filament
Q37100293Rad54 protein stimulates the postsynaptic phase of Rad51 protein-mediated DNA strand exchange
Q44230461Rad54, a Swi2/Snf2-like recombinational repair protein, disassembles Rad51:dsDNA filaments
Q28142095Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl
Q38316899Rapid exchange of A:T base pairs is essential for recognition of DNA homology by human Rad51 recombination protein
Q36328990Real-time measurements of the nucleation, growth and dissociation of single Rad51-DNA nucleoprotein filaments
Q28074245Reappearance from Obscurity: Mammalian Rad52 in Homologous Recombination
Q28207059RecFOR proteins load RecA protein onto gapped DNA to accelerate DNA strand exchange: a universal step of recombinational repair
Q30366224RecO protein initiates DNA recombination and strand annealing through two alternative DNA binding mechanisms.
Q42370440RecO-mediated DNA homology search and annealing is facilitated by SsbA.
Q34661452RecQ helicase and RecJ nuclease provide complementary functions to resect DNA for homologous recombination
Q39867034Recombination activator function of the novel RAD51- and RAD51B-binding protein, human EVL.
Q48018607Recombination at work for meiosis
Q33984330Recombination factors of Saccharomyces cerevisiae
Q33885411Recombination-dependent DNA replication in phage T4.
Q28472580Reconstitution of DNA strand exchange mediated by Rhp51 recombinase and two mediators
Q31151107Recruitment of the recombinational repair machinery to a DNA double-strand break in yeast
Q37433372Regulation of Rad51 recombinase presynaptic filament assembly via interactions with the Rad52 mediator and the Srs2 anti-recombinase.
Q33615409Regulation of double-strand break-induced mammalian homologous recombination by UBL1, a RAD51-interacting protein
Q35466760Regulatory networks integrating cell cycle control with DNA damage checkpoints and double-strand break repair
Q33750366Repair and consequences of double-strand breaks in DNA.
Q34607439Repair of endonuclease-induced double-strand breaks in Saccharomyces cerevisiae: essential role for genes associated with nonhomologous end-joining.
Q90383064Replication Stress Response Links RAD52 to Protecting Common Fragile Sites
Q30667012Replication protein A in Pyrococcus furiosus is involved in homologous DNA recombination
Q27931166Replication protein A is required for meiotic recombination in Saccharomyces cerevisiae.
Q26998910Replication protein A prevents promiscuous annealing between short sequence homologies: Implications for genome integrity
Q33591901Replication protein A: directing traffic at the intersection of replication and repair
Q33701440Rgf1p (Rho1p GEF) is required for double-strand break repair in fission yeast
Q33957777Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage
Q38288580Role of ATP-binding motifs on DNA-binding activity and biological function of Rhp51, a Rad51 homologue in fission yeast
Q29618204Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair
Q24804289Role of Saccharomyces single-stranded DNA-binding protein RPA in the strand invasion step of double-strand break repair
Q37775588Role of homologous recombination in DNA interstrand crosslink repair
Q47714499Role of the human RAD51 protein in homologous recombination and double-stranded-break repair
Q27936614Roles of C-Terminal Region of Yeast and Human Rad52 in Rad51-Nucleoprotein Filament Formation and ssDNA Annealing
Q35171613Roles of Rad51 paralogs for promoting homologous recombination in Leishmania infantum.
Q24554358Rsp5, a ubiquitin-protein ligase, is involved in degradation of the single-stranded-DNA binding protein rfa1 in Saccharomyces cerevisiae
Q39002470SAW1 is required for SDSA double-strand break repair in S. cerevisiae
Q46127945Saccharomyces cerevisiae Mer3 helicase stimulates 3'-5' heteroduplex extension by Rad51; implications for crossover control in meiotic recombination
Q48555364Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer.
Q33302234Sequential and synergistic modification of human RPA stimulates chromosomal DNA repair
Q47377567Sgs1 Binding to Rad51 Stimulates Homology-Directed DNA Repair in Saccharomyces cerevisiae
Q27934163Single strand DNA binding and annealing activities in the yeast recombination factor Rad59.
Q31926025Sources of variation in patient response to radiation treatment
Q49571747Spontaneous self-segregation of Rad51 and Dmc1 DNA recombinases within mixed recombinase filaments.
Q33754225Srs2: the "Odd-Job Man" in DNA repair
Q28260489Stimulation by Rad52 of yeast Rad51-mediated recombination
Q35804759Strand pairing by Rad54 and Rad51 is enhanced by chromatin
Q93074226Structural Basis of Homology-Directed DNA Repair Mediated by RAD52
Q27674555Structure and conformational change of a replication protein A heterotrimer bound to ssDNA
Q24536071Structure of the single-strand annealing domain of human RAD52 protein
Q58699668Structured illumination microscopy imaging reveals localization of replication protein A between chromosome lateral elements during mammalian meiosis
Q57304620Suitability of oligonucleotide-mediated cystic fibrosis gene repair in airway epithelial cells
Q37152658Suppression of the double-strand-break-repair defect of the Saccharomyces cerevisiae rad57 mutant
Q42080852TORC2 is required to maintain genome stability during S phase in fission yeast
Q40387300Tailed duplex DNA is the preferred substrate for Rad51 protein-mediated homologous pairing
Q33781473Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation
Q64079374Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy
Q24323065The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51
Q45345099The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction
Q41911333The Borrelia burgdorferi telomere resolvase, ResT, anneals ssDNA complexed with its cognate ssDNA-binding protein
Q50929606The Caenorhabditis elegans WRN helicase promotes double-strand DNA break repair by mediating end resection and checkpoint activation.
Q45952888The DNA binding preference of RAD52 and RAD59 proteins: implications for RAD52 and RAD59 protein function in homologous recombination.
Q46561573The DNA binding properties of Saccharomyces cerevisiae Rad51 protein
Q39945725The DNA damage checkpoint pathways exert multiple controls on the efficiency and outcome of the repair of a double-stranded DNA gap.
Q33959486The Drosophila melanogaster DmRAD54 gene plays a crucial role in double-strand break repair after P-element excision and acts synergistically with Ku70 in the repair of X-ray damage
Q44389252The Escherichia coli RecA protein complements recombination defective phenotype of the Saccharomyces cerevisiae rad52 mutant cells
Q42107587The F-Box DNA helicase Fbh1 prevents Rhp51-dependent recombination without mediator proteins.
Q34786699The HsRAD51B-HsRAD51C stabilizes the HsRAD51 nucleoprotein filament
Q41762384The Mei5-Sae3 protein complex mediates Dmc1 activity in Saccharomyces cerevisiae
Q42103927The N-terminal DNA-binding domain of Rad52 promotes RAD51-independent recombination in Saccharomyces cerevisiae.
Q47618273The N-terminal domain of the large subunit of human replication protein A binds to Werner syndrome protein and stimulates helicase activity
Q34134658The Rad51 and Dmc1 recombinases: a non-identical twin relationship
Q36571874The Rad52 homologs Rad22 and Rti1 of Schizosaccharomyces pombe are not essential for meiotic interhomolog recombination, but are required for meiotic intrachromosomal recombination and mating-type-related DNA repair
Q34085368The RecOR proteins modulate RecA protein function at 5' ends of single-stranded DNA
Q30917944The Recombination-deficient Mutant RPA (rfa1-t11) Is Displaced Slowly from Single-stranded DNA by Rad51 Protein
Q40063188The Role of PALB2 in the DNA Damage Response and Cancer Predisposition.
Q34608831The Saccharomyces cerevisiae DNA recombination and repair functions of the RAD52 epistasis group inhibit Ty1 transposition
Q30996823The Saccharomyces recombination protein Tid1p is required for adaptation from G2/M arrest induced by a double-strand break.
Q36783620The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55-Rad57 to mediate error-free recombination
Q38945021The Shu complex is a conserved regulator of homologous recombination
Q40765773The Smc5-Smc6 heterodimer associates with DNA through several independent binding domains
Q33254568The Swi5-Sfr1 complex stimulates Rhp51/Rad51- and Dmc1-mediated DNA strand exchange in vitro.
Q24630851The architecture of the human Rad54-DNA complex provides evidence for protein translocation along DNA
Q33867563The breast cancer susceptibility gene, BRCA2: at the crossroads between DNA replication and recombination?
Q27940329The budding yeast mei5 and sae3 proteins act together with dmc1 during meiotic recombination
Q34014665The budding yeast nucleus.
Q39250710The differentiated and conserved roles of Swi5-Sfr1 in homologous recombination.
Q37709212The effects of pprI gene of Deinococcus radiodurans R1 on acute radiation injury of mice exposed to 60Co γ-ray radiation
Q47286312The global role for Cdc13 and Yku70 in preventing telomere resection across the genome.
Q36974995The homologous recombination system of Ustilago maydis
Q45351736The host factor RAD51 is involved in mungbean yellow mosaic India virus (MYMIV) DNA replication
Q28140394The human Rad52 protein exists as a heptameric ring
Q43023458The in vitro activity of a Rad55 homologue from Sulfolobus tokodaii, a candidate mediator in RadA-catalyzed homologous recombination
Q27933902The karyopherin Kap142p/Msn5p mediates nuclear import and nuclear export of different cargo proteins
Q33401051The multi-replication protein A (RPA) system--a new perspective
Q34777694The proteasome factor Bag101 binds to Rad22 and suppresses homologous recombination
Q34804028The role of Alu repeat clusters as mediators of recurrent chromosomal aberrations in tumors
Q27940078The role of DNA double-strand breaks in spontaneous homologous recombination in S. cerevisiae
Q33601047The role of homologous recombination processes in the repair of severe forms of DNA damage in mammalian cells
Q34616322The roles of REV3 and RAD57 in double-strand-break-repair-induced mutagenesis of Saccharomyces cerevisiae
Q35067479The yeast Shu complex utilizes homologous recombination machinery for error-free lesion bypass via physical interaction with a Rad51 paralogue
Q27933466The yeast recombinational repair protein Rad59 interacts with Rad52 and stimulates single-strand annealing
Q41665531Three-dimensional microscopy of the Rad51 recombination protein during meiotic prophase
Q24648825Tid1/Rdh54 promotes colocalization of rad51 and dmc1 during meiotic recombination
Q33728936Timing is everything: cell cycle control of Rad52
Q42534577Transcription and double-strand breaks induce similar mitotic recombination events in Saccharomyces cerevisiae.
Q64387672Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination
Q24318110Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding.
Q36145592Tyrosine phosphorylation stimulates activity of human RAD51 recombinase through altered nucleoprotein filament dynamics
Q30662249UV-induced hyperphosphorylation of replication protein a depends on DNA replication and expression of ATM protein.
Q42733188Vital roles of the second DNA-binding site of Rad52 protein in yeast homologous recombination
Q39793584Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaks
Q34490612Who's who in human recombination: BRCA2 and RAD52.
Q24793741XRCC2 is Required for the Formation of Rad51 Foci Induced by Ionizing Radiation and DNA Cross-Linking Agent Mitomycin C
Q47948111XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes
Q31023832Yeast Rad52 and Rad51 recombination proteins define a second pathway of DNA damage assessment in response to a single double-strand break
Q27931216Yeast Rad54 promotes Rad51-dependent homologous DNA pairing via ATP hydrolysis-driven change in DNA double helix conformation.
Q42996348Yeast cell-free system that catalyses joint-molecule formation in a Rad51p- and Rad52p-dependent fashion
Q30782786Zinc finger of replication protein A, a non-DNA binding element, regulates its DNA binding activity through redox
Q44881166hXRCC2 enhances ADP/ATP processing and strand exchange by hRAD51.
Q27659111γH2A binds Brc1 to maintain genome integrity during S-phase

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