A failure of meiotic chromosome segregation in a fbh1Delta mutant correlates with persistent Rad51-DNA associations

scientific article published on 11 December 2010

A failure of meiotic chromosome segregation in a fbh1Delta mutant correlates with persistent Rad51-DNA associations is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/GKQ977
P8608Fatcat IDrelease_fwfqnwxrk5fltck7ifnq2pofrq
P932PMC publication ID3061084
P698PubMed publication ID21149262
P5875ResearchGate publication ID49675099

P50authorAlexander LorenzQ42573374
Matthew C WhitbyQ42599266
P2093author name stringFekret Osman
Weili Sun
P2860cites workThe novel human DNA helicase hFBH1 is an F-box proteinQ24294566
Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activitiesQ24314262
Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination.Q27929966
Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein familyQ27930009
Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination.Q27931113
Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations.Q27931443
Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange.Q27934450
The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments.Q27934939
Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates?Q27936167
Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinaseQ27938070
Srs2 disassembles Rad51 filaments by a protein-protein interaction triggering ATP turnover and dissociation of Rad51 from DNA.Q27938895
SUMO-modified PCNA recruits Srs2 to prevent recombination during S phaseQ28254244
Stimulation by Rad52 of yeast Rad51-mediated recombinationQ28260489
Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein AQ28260499
A DNA helicase from Schizosaccharomyces pombe stimulated by single-stranded DNA-binding protein at low ATP concentration.Q54561838
The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombeQ67980916
Microtubule-driven nuclear movements and linear elements as meiosis-specific characteristics of the fission yeasts Schizosaccharomyces versatilis and Schizosaccharomyces pombeQ70806582
Meiotic recombination remote from prominent DNA break sites in S. pombeQ77689093
The F-Box DNA helicase Fbh1 prevents Rhp51-dependent recombination without mediator proteins.Q42107587
A SRS2 homolog from Arabidopsis thaliana disrupts recombinogenic DNA intermediates and facilitates single strand annealingQ42121359
Stress-induced phosphorylation of S. pombe Atf1 abrogates its interaction with F box protein Fbh1.Q42461460
A molecular genetic dissection of the evolutionarily conserved N terminus of yeast Rad52.Q42534834
Cooperative roles of vertebrate Fbh1 and Blm DNA helicases in avoidance of crossovers during recombination initiated by replication fork collapseQ42738081
The FANCM ortholog Fml1 promotes recombination at stalled replication forks and limits crossing over during DNA double-strand break repairQ43244381
Interaction with Rad51 is indispensable for recombination mediator function of Rad52.Q44097432
Rad54, a Swi2/Snf2-like recombinational repair protein, disassembles Rad51:dsDNA filamentsQ44230461
Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2pQ46576875
Overlapping mechanisms promote postsynaptic RAD-51 filament disassembly during meiotic double-strand break repair.Q47068714
Requirement for Schizosaccharomyces pombe Top3 in the maintenance of chromosome integrity.Q53635263
Generating crossovers by resolution of nicked Holliday junctions: a role for Mus81-Eme1 in meiosisQ28647386
Mechanism of eukaryotic homologous recombinationQ29547709
An atypical topoisomerase II from Archaea with implications for meiotic recombinationQ29618230
DNA helicase Srs2 disrupts the Rad51 presynaptic filamentQ29618305
Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeastQ29618612
Mus81-Eme1 are essential components of a Holliday junction resolvaseQ29619843
Function of yeast Rad52 protein as a mediator between replication protein A and the Rad51 recombinaseQ29620205
Rad51 and Rad54 ATPase activities are both required to modulate Rad51-dsDNA filament dynamicsQ30444605
Role of the Schizosaccharomyces pombe F-Box DNA helicase in processing recombination intermediatesQ30797538
The Srs2 helicase activity is stimulated by Rad51 filaments on dsDNA: implications for crossover incidence during mitotic recombinationQ33317888
Essential and distinct roles of the F-box and helicase domains of Fbh1 in DNA damage repair.Q33321986
Interaction with RPA is necessary for Rad52 repair center formation and for its mediator activityQ33360205
Single Holliday junctions are intermediates of meiotic recombinationQ33576921
The SRS2 suppressor of rad6 mutations of Saccharomyces cerevisiae acts by channeling DNA lesions into the RAD52 DNA repair pathwayQ33956390
Analysis of mitotic and meiotic defects in Saccharomyces cerevisiae SRS2 DNA helicase mutantsQ33959832
RTEL-1 enforces meiotic crossover interference and homeostasisQ34102182
Conserved and nonconserved proteins for meiotic DNA breakage and repair in yeastsQ34645078
Terminal association of Rad54 protein with the Rad51-dsDNA filamentQ34772734
The fission yeast SPB component Cut12 links bipolar spindle formation to mitotic control.Q35195721
Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies.Q35662119
RADH, a gene of Saccharomyces cerevisiae encoding a putative DNA helicase involved in DNA repair. Characteristics of radH mutants and sequence of the geneQ35945829
Making crossovers during meiosisQ36295514
The human F-Box DNA helicase FBH1 faces Saccharomyces cerevisiae Srs2 and postreplication repair pathway rolesQ36315640
Metabolic suppressors of trimethoprim and ultraviolet light sensitivities of Saccharomyces cerevisiae rad6 mutantsQ36334143
Basic methods for fission yeastQ36405219
Crossover promotion and prevention.Q36542036
The Rad52 homologs Rad22 and Rti1 of Schizosaccharomyces pombe are not essential for meiotic interhomolog recombination, but are required for meiotic intrachromosomal recombination and mating-type-related DNA repairQ36571874
Some disassembly required: role of DNA translocases in the disruption of recombination intermediates and dead-end complexesQ36596244
Homologous chromosome pairing in Schizosaccharomyces pombeQ36638134
The fission yeast BLM homolog Rqh1 promotes meiotic recombinationQ36778014
RecQ helicases queuing with Srs2 to disrupt Rad51 filaments and suppress recombinationQ37023116
RAD54 controls access to the invading 3'-OH end after RAD51-mediated DNA strand invasion in homologous recombination in Saccharomyces cerevisiaeQ37077426
DNA strand annealing is promoted by the yeast Rad52 proteinQ37293228
Analysis of Schizosaccharomyces pombe meiosis by nuclear spreading.Q37580790
The FANCM family of DNA helicases/translocases.Q37684306
Fbh1 limits Rad51-dependent recombination at blocked replication forks.Q41865081
P275copyright licenseCreative Commons Attribution-NonCommercial 2.5 GenericQ19113746
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P1104number of pages14
P304page(s)1718-1731
P577publication date2010-12-11
P1433published inNucleic Acids ResearchQ135122
P1476titleA failure of meiotic chromosome segregation in a fbh1Delta mutant correlates with persistent Rad51-DNA associations
P478volume39

Reverse relations

cites work (P2860)
Q34631032Activity-dependent expression of neuronal PAS domain-containing protein 4 (npas4a) in the developing zebrafish brain.
Q28550285Dbl2 Regulates Rad51 and DNA Joint Molecule Metabolism to Ensure Proper Meiotic Chromosome Segregation
Q42078533Involvement of Schizosaccharomyces pombe rrp1+ and rrp2+ in the Srs2- and Swi5/Sfr1-dependent pathway in response to DNA damage and replication inhibition
Q48174147Modulation of meiotic homologous recombination by DNA helicases
Q35233502Multiple regulation of Rad51-mediated homologous recombination by fission yeast Fbh1.
Q24603667Mus81 nuclease and Sgs1 helicase are essential for meiotic recombination in a protist lacking a synaptonemal complex
Q30538694Quantitative analysis of chromosome condensation in fission yeast
Q91871060S. cerevisiae Srs2 helicase ensures normal recombination intermediate metabolism during meiosis and prevents accumulation of Rad51 aggregates
Q34146247SCF ensures meiotic chromosome segregation through a resolution of meiotic recombination intermediates
Q28729084The fission yeast FANCM ortholog directs non-crossover recombination during meiosis

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