Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain

scientific article

Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain is …
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scholarly articleQ13442814

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P356DOI10.1093/EMBOJ/19.4.504
P3181OpenCitations bibliographic resource ID4883967
P932PMC publication ID305588
P698PubMed publication ID10675319
P5875ResearchGate publication ID24677832

P2093author name stringY A Muller
G L Hammond
G V Avvakumov
D Dales
G Sklenar
I Grishkovskaya
P2860cites workComplete amino acid sequence of human thyroxine-binding globulin deduced from cloned DNA: close homology to the serine antiproteasesQ24296272
Primary structure of human corticosteroid binding globulin, deduced from hepatic and pulmonary cDNAs, exhibits homology with serine protease inhibitorsQ24297884
Improved methods for building protein models in electron density maps and the location of errors in these modelsQ26776980
PROCHECK: a program to check the stereochemical quality of protein structuresQ26778411
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Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonistQ27619550
The structure of the ligand-binding domain of neurexin Ibeta: regulation of LNS domain function by alternative splicingQ27619961
The crystal structure of a laminin G-like module reveals the molecular basis of alpha-dystroglycan binding to laminins, perlecan, and agrinQ27620848
Structure of concanavalin A at 2.4-A resolutionQ27729062
Structure of pentameric human serum amyloid P componentQ27731194
High-resolution crystal structures of delta5-3-ketosteroid isomerase with and without a reaction intermediate analogueQ27747692
Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domainsQ27757822
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The nuclear receptor superfamily: the second decadeQ27860725
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wARP: improvement and extension of crystallographic phases by weighted averaging of multiple-refined dummy atomic modelsQ27860981
The CCP4 suite: programs for protein crystallographyQ27861090
Characterization of Gas6, a member of the superfamily of G domain-containing proteins, as a ligand for Rse and AxlQ28277798
There are two forms of androgen binding protein in human testes. Comparison of their protomeric variants with serum testosterone-estradiol binding globulinQ69889496
Steroid-binding and dimerization domains of human sex hormone-binding globulin partially overlap: steroids and Ca2+ stabilize dimer formationQ72160241
Crystallization of the N-terminal domain of human sex hormone-binding globulin, the major sex steroid carrier in bloodQ73427757
Evaluation of single-crystal X-ray diffraction data from a position-sensitive detectorQ107329121
Atomic structure and chemistry of human serum albuminQ28283217
Tyro-3 family receptors are essential regulators of mammalian spermatogenesisQ28585555
Dystroglycan versatilityQ33657933
Amino acid sequence of the sex steroid binding protein of human blood plasmaQ34183056
Structure and function of laminin: anatomy of a multidomain glycoproteinQ34372088
Sex hormone-binding globulin: gene organization and structure/function analysesQ34410972
Merging extracellular domains: fold prediction for laminin G-like and amino-terminal thrombospondin-like modules based on homology to pentraxinsQ34457974
Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpinsQ34515383
Estradiol causes the rapid accumulation of cAMP in human prostateQ35450662
The free hormone hypothesis. Distinction from the free hormone transport hypothesisQ36172112
Hormonal and immunological aspects of the phylogeny of sex steroid binding plasma proteinQ36401300
Synthetic peptides from the carboxy-terminal globular domain of the A chain of laminin: their ability to promote cell adhesion and neurite outgrowth, and interact with heparin and the beta 1 integrin subunitQ36532915
The functions of corticosteroid-binding globulin and sex hormone-binding globulin: recent advancesQ37909541
Sex hormone-binding globulin/androgen-binding protein: steroid-binding and dimerization domainsQ38294818
Structure-function relationships of rat androgen--binding protein/human sex-hormone binding globulin: the effect of mutagenesis on steroid-binding parametersQ38306670
Structure, function, and regulation of androgen-binding protein/sex hormone-binding globulinQ38312952
Photoaffinity labeling of homologous Met-133 and Met-139 amino acids of rabbit and sheep sex hormone-binding globulins with the unsubstituted Delta 6-testosterone photoreagent.Q38332775
Protein–DNA and protein–hormone interactions in prealbumin: a model of the thyroid hormone nuclear receptor?Q40119466
The serum transport of steroid hormonesQ40244003
Receptors for androgen-binding proteins: internalization and intracellular signalling.Q40455222
Regulation of signal transduction and signal diversity by receptor oligomerizationQ40592846
Lipid-binding proteins: a family of fatty acid and retinoid transport proteinsQ40737991
SHBG region of the anticoagulant cofactor protein S: secondary structure prediction, circular dichroism spectroscopy, and analysis of naturally occurring mutationsQ40874513
Hematopoietic receptor complexesQ41114835
Determinants of steroid hormone bioavailabilityQ41505386
Sequence and functional relationships between androgen-binding protein/sex hormone-binding globulin and its homologs protein S, Gas6, laminin, and agrinQ41591437
Localization of the steroid-binding site of the human sex steroid-binding protein of plasma (SBP or SHBG) by site-directed mutagenesisQ41602683
Nongenomic actions of steroid hormones in reproductive tissuesQ41717587
Direct evidence for the localization of the steroid-binding site of the plasma sex steroid-binding protein (SBP or SHBG) at the interface between the subunitsQ42845116
The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamilyQ43709450
Studies on thyroid hormone-binding proteins. II. Binding of thyroid hormones, retinol-binding protein, and fluorescent probes to prealbumin and effects of thyroxine on prealbumin subunit self associationQ46093574
Depicting topology and handedness in jellyroll structuresQ47636894
A High-Affinity Androgen-Binding Protein (ABP) in Rat Testis: Evidence for Secretion into Efferent Duct Fluid and Absorption by Epididymis1Q47991941
Sex hormone-binding globulin, androgen-binding protein, and vitamin K-dependent protein S are homologous to laminin A, merosin, and Drosophila crumbs proteinQ48179426
Laminin-binding protein 120 from brain is closely related to the dystrophin-associated glycoprotein, dystroglycan, and binds with high affinity to the major heparin binding domain of lamininQ48249023
Secondary structure and shape of plasma sex steroid-binding protein--comparison with domain G of laminin results in a structural model of plasma sex steroid-binding proteinQ50942688
Binding site for C4b-binding protein in vitamin K-dependent protein S fully contained in carboxy-terminal laminin-G-type repeats. A study using recombinant factor IX-protein S chimeras and surface plasmon resonanceQ50958368
MCF-7 cell progesterone receptor (PGR) is additionally modulated by sex steroid binding protein (SBP) and its membrane receptor (SBP-R) through cAMP and PKA.Q51030394
Resolution of the steroid-binding and dimerization domains of human sex hormone-binding globulin by expression in Escherichia coli.Q54615591
Generalized method of determining heavy-atom positions using the difference Patterson functionQ56878144
SHBG region of the anticoagulant cofactor protein S: Secondary structure prediction, circular dichroism spectroscopy, and analysis of naturally occurring mutationsQ57904273
Neural Targeting of Mycobacterium leprae Mediated by the G Domain of the Laminin-α2 ChainQ59647724
Characterization of Met-139 as the photolabeled amino acid residue in the steroid binding site of sex hormone binding globulin using delta 6 derivatives of either testosterone or estradiol as unsubstituted photoaffinity labeling reagentsQ68026069
Structure/function analyses of human sex hormone-binding globulin by site-directed mutagenesisQ68100615
Identification of lysine 134 in the steroid-binding site of the sex steroid-binding protein of human plasmaQ68359007
Delineation and synthesis of the membrane receptor-binding domain of sex hormone-binding globulinQ68479872
Molecular characterization of the sex steroid binding protein (SBP) of plasma. Re-examination of rabbit SBP and comparison with the human, macaque and baboon proteinsQ69597071
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectcrystal structureQ895901
P304page(s)504-12
P577publication date2000-02-15
P1433published inThe EMBO JournalQ1278554
P1476titleCrystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain
P478volume19

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cites work (P2860)
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