| scholarly article | Q13442814 |
| P50 | author | Graziano Pinna | Q87954226 |
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| Gas chromatographic-mass fragmentographic quantitation of 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone) and its precursors in blood and brain of adrenalectomized and castrated rats. | Q51601652 | ||
| Participation of mitochondrial diazepam binding inhibitor receptors in the anticonflict, antineophobic and anticonvulsant action of 2-aryl-3-indoleacetamide and imidazopyridine derivatives. | Q51666197 | ||
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| The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5α-dihydroprogesterone in psychiatric disorders | Q59486481 | ||
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| Is mood chemistry? | Q28237445 | ||
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| Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptake | Q28293369 | ||
| Tianeptine, a selective enhancer of serotonin uptake in rat brain | Q28298333 | ||
| 2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR) | Q28326791 | ||
| Brain allopregnanolone regulates the potency of the GABAA receptor agonist muscimol | Q29541102 | ||
| Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants | Q29547516 | ||
| Epigenetic regulation in psychiatric disorders | Q29616296 | ||
| Neurobiology of depression | Q29619932 | ||
| Decreased corticolimbic allopregnanolone expression during social isolation enhances contextual fear: A model relevant for posttraumatic stress disorder | Q30493113 | ||
| The promoter of the rat 5alpha-reductase type 1 gene is bidirectional and Sp1-dependent | Q33267853 | ||
| Role of the amygdala in antidepressant effects on hippocampal cell proliferation and survival and on depression-like behavior in the rat. | Q33523048 | ||
| Antidepressant stimulation of CDP-diacylglycerol synthesis does not require monoamine reuptake inhibition | Q33526872 | ||
| Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives | Q33707601 | ||
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| History and evolution of the monoamine hypothesis of depression. | Q33896390 | ||
| Neurosteroids act on recombinant human GABAA receptors | Q34187011 | ||
| Neurosteroid modulation of GABAA receptors | Q34275980 | ||
| Use of benzodiazepines in social anxiety disorder, generalized anxiety disorder, and posttraumatic stress disorder | Q34312612 | ||
| Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice | Q34398750 | ||
| Neurosteroids: beginning of the story | Q34400441 | ||
| Allopregnanolone microinjected into the lateral septum or dorsal hippocampus reduces immobility in the forced swim test: participation of the GABAA receptor. | Q43276823 | ||
| Rapid regulation of steroidogenesis by mitochondrial protein import | Q43447990 | ||
| Serum allopregnanolone in women with postpartum "blues". | Q43518096 | ||
| Mitochondrial processing of newly synthesized steroidogenic acute regulatory protein (StAR), but not total StAR, mediates cholesterol transfer to cytochrome P450 side chain cleavage enzyme in adrenal cells | Q43752292 | ||
| GABA(A) receptor-modulating neuroactive steroid composition in patients with panic disorder before and during paroxetine treatment | Q43843063 | ||
| The influence of subunit composition on the interaction of neurosteroids with GABA(A) receptors | Q44169994 | ||
| Kinetics of allopregnanolone formation catalyzed by human 3 alpha-hydroxysteroid dehydrogenase type III (AKR1C2). | Q44205130 | ||
| Region-specific dysregulation of allopregnanolone brain content in the olfactory bulbectomized rat model of depression | Q44451567 | ||
| Long-term social isolation enhances picrotoxin seizure susceptibility in mice: up-regulatory role of endogenous brain allopregnanolone in GABAergic systems | Q44574428 | ||
| Chronic antidepressants reverse cerebrocortical allopregnanolone decline in the olfactory-bulbectomized rat. | Q44748223 | ||
| Structure-activity relationships in steroidal anaesthetics | Q45093844 | ||
| Mechanisms of anger and treatment outcome in combat veterans with posttraumatic stress disorder. | Q45331951 | ||
| Reduced GABAA benzodiazepine receptor binding in veterans with post-traumatic stress disorder. | Q45332257 | ||
| Fear-potentiated startle conditioning to explicit and contextual cues in Gulf War veterans with posttraumatic stress disorder | Q45334866 | ||
| Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling | Q46182373 | ||
| Reversal of caffeine-induced anxiety by neurosteroid 3-alpha-hydroxy-5-alpha-pregnane-20-one in rats | Q46425241 | ||
| Progesterone metabolite allopregnanolone in women with premenstrual syndrome | Q46518358 | ||
| Antidepressant effect and changes of GABAA receptor gamma2 subunit mRNA after hippocampal administration of allopregnanolone in rats | Q46727041 | ||
| The intrahippocampal administration of the neurosteroid allopregnanolone blocks the audiogenic seizures induced by nicotine. | Q46780376 | ||
| Permissive role of brain allopregnanolone content in the regulation of pentobarbital-induced righting reflex loss | Q48148744 | ||
| Norfluoxetine enantiomers as inhibitors of serotonin uptake in rat brain | Q48269583 | ||
| Can the antidysphoric and anxiolytic profiles of selective serotonin reuptake inhibitors be related to their ability to increase brain 3 alpha, 5 alpha-tetrahydroprogesterone (allopregnanolone) availability? | Q48355449 | ||
| The anticonvulsant effects of allopregnanolone against amygdala-kindled seizures in female rats | Q48378748 | ||
| Infusions of 5alpha-pregnan-3alpha-ol-20-one (3alpha,5alpha-THP) to the ventral tegmental area, but not the substantia nigra, enhance exploratory, anti-anxiety, social and sexual behaviours and concomitantly increase 3alpha,5alpha-THP concentrations | Q48382066 | ||
| GABA(A) receptor alpha4 subunit suppression prevents withdrawal properties of an endogenous steroid | Q48472565 | ||
| The anxiolytic-like effects of allopregnanolone vary as a function of intracerebral microinfusion site: the amygdala, medial prefrontal cortex, or hippocampus | Q48568680 | ||
| Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor | Q48640592 | ||
| Diazepam binding inhibitor (DBI): a peptide with multiple biological actions | Q34497484 | ||
| Imidazenil and diazepam increase locomotor activity in mice exposed to protracted social isolation. | Q34573086 | ||
| DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes | Q34576655 | ||
| Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites | Q34582058 | ||
| S-norfluoxetine microinfused into the basolateral amygdala increases allopregnanolone levels and reduces aggression in socially isolated mice | Q34587659 | ||
| Neuroactive steroids in depression and anxiety disorders: clinical studies | Q34589630 | ||
| Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice | Q34713732 | ||
| Involvement of neurosteroids in the anxiolytic-like effects of AC-5216 in mice | Q34737212 | ||
| Effects of antidepressant treatment on neuroactive steroids in major depression | Q34749115 | ||
| In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine | Q34763151 | ||
| Neurosteroid biosynthesis regulates sexually dimorphic fear and aggressive behavior in mice. | Q34778055 | ||
| Neurosteroids: endogenous bimodal modulators of the GABAA receptor. Mechanism of action and physiological significance | Q35254149 | ||
| Selective versus multi-transmitter antidepressants: are two mechanisms better than one? | Q35717209 | ||
| Neurosteroids and neuroactive drugs in mental disorders | Q35749950 | ||
| Nuclear receptor-mediated transactivation through interaction with Sp proteins | Q35805048 | ||
| Steroid hormone fluctuations and GABA(A)R plasticity. | Q36101683 | ||
| Transcription factor Sp1 functions as an anchor protein in gene transcription of human 12(S)-lipoxygenase | Q36240867 | ||
| Relevance of endogenous 3alpha-reduced neurosteroids to depression and antidepressant action | Q36297266 | ||
| Neurocircuitry models of posttraumatic stress disorder and extinction: human neuroimaging research--past, present, and future | Q36571175 | ||
| Pharmacologic significance of the structural heterogeneity of the GABAA receptor-chloride ion channel complex | Q36633425 | ||
| GABA(A) receptor neurotransmission dysfunction in a mouse model of social isolation-induced stress: possible insights into a non-serotonergic mechanism of action of SSRIs in mood and anxiety disorders | Q36799974 | ||
| The complex roles of neurosteroids in depression and anxiety disorders. | Q36998564 | ||
| Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography | Q37243720 | ||
| GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability | Q37356501 | ||
| Increasing 3alpha,5alpha-THP following inhibition of neurosteroid biosynthesis in the ventral tegmental area reinstates anti-anxiety, social, and sexual behavior of naturally receptive rats | Q37357913 | ||
| Fluoxetine and norfluoxetine stereospecifically facilitate pentobarbital sedation by increasing neurosteroids | Q37647632 | ||
| The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity | Q37699054 | ||
| Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder | Q38841364 | ||
| Pharmacological management of post-traumatic stress disorder: clinical summary of a five-year retrospective study, 1990-1995. | Q39453557 | ||
| Norepinephrine in depressive reactions. A review | Q40028374 | ||
| Benzodiazepines on trial: a research strategy for their rehabilitation | Q41008175 | ||
| Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action | Q41336171 | ||
| Anxiolytic activity of the progesterone metabolite 5α-pregnan-3α-ol-20-one | Q42614851 | ||
| On the putative physiological role of allopregnanolone on GABA(A) receptor function | Q42693899 | ||
| Neuropeptide Y Y1 receptors in the central nucleus of amygdala mediate the anxiolytic-like effect of allopregnanolone in mice: Behavioral and immunocytochemical evidences. | Q43199137 | ||
| Dopamine is involved in the antidepressant-like effect of allopregnanolone in the forced swimming test in female rats. | Q43222257 | ||
| Neurosteroids: endogenous allosteric modulators of GABA(A) receptors. | Q43275760 | ||
| P433 | issue | 5-6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | brain | Q1073 |
| post-traumatic stress disorder | Q202387 | ||
| P304 | page(s) | 438-450 | |
| P577 | publication date | 2010-09-01 | |
| P1433 | published in | Behavioural Pharmacology | Q15754239 |
| P1476 | title | In a mouse model relevant for post-traumatic stress disorder, selective brain steroidogenic stimulants (SBSS) improve behavioral deficits by normalizing allopregnanolone biosynthesis | |
| P478 | volume | 21 |
| Q49598739 | A novel therapeutic approach for treatment of catamenial epilepsy |
| Q64899064 | Animal Models of PTSD: The Socially Isolated Mouse and the Biomarker Role of Allopregnanolone. |
| Q50694633 | Anxiolytic-like effects of YL-IPA08, a potent ligand for the translocator protein (18 kDa) in animal models of post-traumatic stress disorder. |
| Q48181478 | Enhanced aggressive behaviour in a mouse model of depression |
| Q28241963 | GABAA receptor-acting neurosteroids: a role in the development and regulation of the stress response |
| Q30428666 | Ganaxolone improves behavioral deficits in a mouse model of post-traumatic stress disorder |
| Q34228092 | Is progesterone a worthy candidate as a novel therapy for traumatic brain injury? |
| Q47569123 | Loneliness, Social Isolation, and Cardiovascular Health |
| Q26863668 | Loneliness: clinical import and interventions |
| Q91646274 | Neurosteroid Levels in the Orbital Frontal Cortex of Subjects with PTSD and Controls: A Preliminary Report |
| Q38096797 | Neurosteroid and neurotransmitter alterations in Parkinson's disease |
| Q34556039 | Neurosteroid biosynthesis downregulation and changes in GABAA receptor subunit composition: A biomarker axis in stress-induced cognitive and emotional impairment. |
| Q21129366 | Neurosteroids and GABA(A) Receptor Interactions: A Focus on Stress |
| Q30467322 | Neurosteroids reduce social isolation-induced behavioral deficits: a proposed link with neurosteroid-mediated upregulation of BDNF expression |
| Q26781604 | Non-mammalian models in behavioral neuroscience: consequences for biological psychiatry |
| Q42393901 | Novel modulatory effects of neurosteroids and benzodiazepines on excitatory and inhibitory neurons excitability: a multi-electrode array recording study |
| Q36036726 | Progesterone attenuates depressive behavior of younger and older adult C57/BL6, wildtype, and progesterone receptor knockout mice |
| Q37934335 | Reconsidering GHB: orphan drug or new model antidepressant? |
| Q92341842 | Resilience as a translational endpoint in the treatment of PTSD |
| Q34587659 | S-norfluoxetine microinfused into the basolateral amygdala increases allopregnanolone levels and reduces aggression in socially isolated mice |
| Q48005275 | SSRIs and the female brain--potential for utilizing steroid-stimulating properties to treat menstrual cycle-linked dysphorias. |
| Q37163160 | Sex dependent influence of a functional polymorphism in steroid 5-α-reductase type 2 (SRD5A2) on post-traumatic stress symptoms |
| Q50172986 | Social isolation induces autophagy in the mouse mammary gland: link to increased mammary cancer risk. |
| Q37433677 | Targeting neurosteroidogenesis as therapy for PTSD. |
| Q59812520 | The 18 kDa Translocator Protein (TSPO) Overexpression in Hippocampal Dentate Gyrus Elicits Anxiolytic-Like Effects in a Mouse Model of Post-traumatic Stress Disorder |
| Q48051959 | The inulin-type oligosaccharides extract from morinda officinalis, a traditional Chinese herb, ameliorated behavioral deficits in an animal model of post-traumatic stress disorder |
| Q37458179 | Toward a neurology of loneliness |
| Q38184971 | Traumatic brain injury using mouse models. |
| Q35631836 | Up-regulation of neurosteroid biosynthesis as a pharmacological strategy to improve behavioural deficits in a putative mouse model of post-traumatic stress disorder |
| Q36289293 | Why may allopregnanolone help alleviate loneliness? |
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