Nuclear receptor-mediated transactivation through interaction with Sp proteins

scientific article published on January 2004

Nuclear receptor-mediated transactivation through interaction with Sp proteins is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0079-6603(04)77001-4
P698PubMed publication ID15196889

P50authorKyounghyun KimQ64671757
Stephen SafeQ87666139
P2093author name stringKyounghyun Kim
P2860cites workThe transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1Q22001451
Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activatorsQ22009365
Composite co-activator ARC mediates chromatin-directed transcriptional activationQ22009528
Functional interactions between Sp1 or Sp3 and the helicase-like transcription factor mediate basal expression from the human plasminogen activator inhibitor-1 geneQ22010204
Interaction between the two ubiquitously expressed transcription factors NF-Y and Sp1Q22010213
Ligand-, cell-, and estrogen receptor subtype (alpha/beta)-dependent activation at GC-rich (Sp1) promoter elementsQ22253217
Inhibition of vascular endothelial growth factor expression in HEC1A endometrial cancer cells through interactions of estrogen receptor alpha and Sp3 proteinsQ22254113
The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formationQ24292169
Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activatorsQ24309765
Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2FQ24317554
ER beta: identification and characterization of a novel human estrogen receptorQ24317610
Distinct Subdomains of Human TAFII130 Are Required for Interactions with Glutamine-Rich Transcriptional ActivatorsQ24522713
The promyelocytic leukemia protein interacts with Sp1 and inhibits its transactivation of the epidermal growth factor receptor promoterQ24522845
Transcriptional autorepression of Msx1 gene is mediated by interactions of Msx1 protein with a multi-protein transcriptional complex containing TATA-binding protein, Sp1 and cAMP-response-element-binding protein-binding protein (CBP/p300)Q24531481
Estrogen receptor-mediated activation of the serum response element in MCF-7 cells through MAPK-dependent phosphorylation of Elk-1.Q38304978
Nuclear receptors modulate the interaction of Sp1 and GC-rich DNA via ternary complex formationQ38306064
The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulatorQ38306731
Unique protein determinants of the subtype-selective ligand responses of the estrogen receptors (ERalpha and ERbeta ) at AP-1 sitesQ38307076
Genetic dissection of hTAF(II)130 defines a hydrophobic surface required for interaction with glutamine-rich activatorsQ38318474
Mechanisms of transcriptional activation of bcl-2 gene expression by 17beta-estradiol in breast cancer cellsQ38318911
Transcriptional activation of E2F1 gene expression by 17beta-estradiol in MCF-7 cells is regulated by NF-Y-Sp1/estrogen receptor interactionsQ38321692
Transcriptional activation of insulin-like growth factor-binding protein-4 by 17beta-estradiol in MCF-7 cells: role of estrogen receptor-Sp1 complexesQ38324335
Estrogen-Induced Retinoic Acid Receptor α1 Gene Expression: Role of Estrogen Receptor-Sp1 ComplexQ38336635
Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiationQ38345845
Role of estrogen receptor/Sp1 complexes in estrogen-induced heat shock protein 27 gene expressionQ38351797
COUP-TF upregulates NGFI-A gene expression through an Sp1 binding site.Q39445171
An inhibitor domain in Sp3 regulates its glutamine-rich activation domains.Q39461480
Transcription factor Sp3 is regulated by acetylationQ39515925
Sp1 activation of a TATA-less promoter requires a species-specific interaction involving transcription factor IID.Q39722755
Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF.Q40016157
The von Hippel-Lindau Tumor Suppressor Gene Product Interacts with Sp1 To Repress Vascular Endothelial Growth Factor Promoter ActivityQ40023447
Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-betaQ40370863
The uteroglobin gene region: hormonal regulation, repetitive elements and complete nucleotide sequence of the geneQ40490937
Estrogen regulation of vascular endothelial growth factor gene expression in ZR-75 breast cancer cells through interaction of estrogen receptor alpha and SP proteinsQ40612609
Transcriptional activation of rat creatine kinase B by 17β‐estradiol in MCF‐7 cells involves an estrogen responsive element and GC‐rich sitesQ40762894
Induction of cPLA2 in lung epithelial cells and non-small cell lung cancer is mediated by Sp1 and c-JunQ40780263
Complex phenotype of mice homozygous for a null mutation in the Sp4 transcription factor gene.Q40782853
Impaired ossification in mice lacking the transcription factor Sp3.Q40789957
The signal transduction pathway underlying ion channel gene regulation by SP1-C-Jun interactionsQ40819193
Independent repression of a GC-rich housekeeping gene by Sp1 and MAZ involves the same cis-elementsQ40819762
Mutant p53 forms a complex with Sp1 on HIV-LTR DNA.Q40837373
Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.Q40870310
The receptor for advanced glycation end products is induced by the glycation products themselves and tumor necrosis factor-alpha through nuclear factor-kappa B, and by 17beta-estradiol through Sp-1 in human vascular endothelial cellsQ40877248
Differential role for Sp1/Sp3 transcription factors in the regulation of the promoter activity of multiple cyclin-dependent kinase inhibitor genesQ40903617
An important von Hippel-Lindau tumor suppressor domain mediates Sp1-binding and self-associationQ40914690
Combinatorial Action of HNF3 and Sp Family Transcription Factors in the Activation of the Rabbit Uteroglobin/CC10 PromoterQ41041320
Histone Deacetylase Inhibitor Activates the WAF1/Cip1 Gene Promoter through the Sp1 SitesQ41066638
Butyrate Activates the WAF1/Cip1 Gene Promoter through Sp1 Sites in a p53-negative Human Colon Cancer Cell LineQ41092576
Functional Interactions between the Estrogen Receptor and the Transcription Activator Sp1 Regulate the Estrogen-dependent Transcriptional Activity of the Vitellogenin A1 ioPromoterQ41099094
Transcriptional activities of estrogen and glucocorticoid receptors are functionally integrated at the AP-1 response elementQ41102965
Cooperative interaction between AhR.Arnt and Sp1 for the drug-inducible expression of CYP1A1 gene.Q41197895
Members of the Sp transcription factor family control transcription from the uteroglobin promoterQ41343650
E1a activation of insulin receptor gene expression is mediated by Sp1-binding sitesQ41374856
Cooperation by sterol regulatory element-binding protein and Sp1 in sterol regulation of low density lipoprotein receptor geneQ41379512
Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcriptionQ41684614
GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinaseQ41718635
Transcriptional regulation by the Sp family proteins.Q41756422
Distinct regions of Sp1 modulate DNA binding and transcriptional activationQ42018379
Progesterone Regulates Transcription of the p21 Cyclindependent Kinase Inhibitor Gene through Sp1 and CBP/p300Q42454022
Estrogen induces adenosine deaminase gene expression in MCF-7 human breast cancer cells: role of estrogen receptor-Sp1 interactionsQ42466486
Coactivators for a proline-rich activator purified from the multisubunit human TFIID complexQ42468497
Regulation of constitutive gene expression through interactions of Sp1 protein with the nuclear aryl hydrocarbon receptor complexQ42477028
Androgen induction of cyclin-dependent kinase inhibitor p21 gene: role of androgen receptor and transcription factor Sp1 complexQ42487932
Efficient TGF-beta induction of the Smad7 gene requires cooperation between AP-1, Sp1, and Smad proteins on the mouse Smad7 promoterQ42488929
Small inhibitory RNA duplexes for Sp1 mRNA block basal and estrogen-induced gene expression and cell cycle progression in MCF-7 breast cancer cellsQ42522132
Synergistic cooperation between Sp1 and Smad3/Smad4 mediates transforming growth factor beta1 stimulation of alpha 2(I)-collagen (COL1A2) transcriptionQ42795742
Growth/cell cycle regulation of Sp1 phosphorylationQ42822980
Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogensQ42828921
Identification of an estrogen response element upstream of the human c-fos gene that binds the estrogen receptor and the AP-1 transcription factorQ35875165
Cathepsin D gene is controlled by a mixed promoter, and estrogens stimulate only TATA-dependent transcription in breast cancer cellsQ36037249
Eukaryotic coactivators associated with the TATA box binding proteinQ36354814
Pleiotropic effect of the human T-cell leukemia virus Tax protein on the DNA binding activity of eukaryotic transcription factorsQ36461344
Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family membersQ36486862
Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibilityQ36568052
Species-specific interaction of the glutamine-rich activation domains of Sp1 with the TATA box-binding proteinQ36647515
Increased expression and DNA-binding activity of transcription factor Sp1 in doxorubicin-resistant HL-60 leukemia cellsQ36729898
In vitro activation of transcription by the human T-cell leukemia virus type I Tax proteinQ36814470
The retinoblastoma gene product regulates Sp1-mediated transcriptionQ36816438
Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interactionQ37135126
Functional interaction between c-Jun and promoter factor Sp1 in epidermal growth factor-induced gene expression of human 12(S)-lipoxygenaseQ37245171
Regulation of vascular endothelial growth factor (VEGF) gene transcription by estrogen receptors alpha and betaQ37268581
Direct physical interactions between HNF-4 and Sp1 mediate synergistic transactivation of the apolipoprotein CIII promoter.Q38292814
Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor proteinQ38300297
Interaction of Huntington disease protein with transcriptional activator Sp1Q24537687
The transcription factors Sp1 and Oct-1 interact physically to regulate human U2 snRNA gene expressionQ24546618
A tale of three fingers: the family of mammalian Sp/XKLF transcription factorsQ24548846
Myogenic basic helix-loop-helix proteins and Sp1 interact as components of a multiprotein transcriptional complex required for activity of the human cardiac alpha-actin promoterQ24554518
The retinoblastoma-susceptibility gene product binds directly to the human TATA-binding protein-associated factor TAFII250Q24561428
Evidence for physical interaction between the zinc-finger transcription factors YY1 and Sp1Q24562189
A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free systemQ24601592
O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capabilityQ24602222
Cloning of a novel receptor expressed in rat prostate and ovaryQ24607949
O Glycosylation of an Sp1-Derived Peptide Blocks Known Sp1 Protein InteractionsQ24644353
Interaction of the v-Rel oncoprotein with cellular transcription factor Sp1Q24645607
Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interactionQ24650233
Purification of transcription cofactor complex CRSPQ24650325
Association of p107 with Sp1: genetically separable regions of p107 are involved in regulation of E2F- and Sp1-dependent transcriptionQ24651154
The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoterQ24653488
In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factorQ24655901
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathwaysQ24681762
The nuclear receptor superfamily: the second decadeQ27860725
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.Q27930548
Sp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-induced alpha 2(I) collagen expression in human glomerular mesangial cellsQ28140115
Estrogen receptor interaction with co-activators and co-repressorsQ28140995
Sp1 and SF-1 interact and cooperate in the regulation of human steroidogenic acute regulatory protein gene expressionQ28142275
Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1Q28190792
Mammalian Srb/Mediator complex is targeted by adenovirus E1A proteinQ28198008
Identification of a critical Sp1 site within the endoglin promoter and its involvement in the transforming growth factor-beta stimulationQ28204253
Nuclear receptor minireview seriesQ28207308
Structure, function, and activator-induced conformations of the CRSP coactivatorQ28217949
Synergistic activation by the glutamine-rich domains of human transcription factor Sp1Q28245874
COUP-TF and Sp1 Interact and Cooperate in the Transcriptional Activation of the Human Immunodeficiency Virus Type 1 Long Terminal Repeat in Human Microglial CellsQ28255786
Human estrogen receptor beta-gene structure, chromosomal localization, and expression patternQ28256533
NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcriptionQ28282085
Synergistic Activation of theN-Methyl-d-aspartate Receptor Subunit 1 Promoter by Myocyte Enhancer Factor 2C and Sp1Q28283417
Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domainQ28295806
Estrogen regulation of cyclin D1 gene expression in ZR-75 breast cancer cells involves multiple enhancer elementsQ43643514
Regulation of prothymosin alpha gene expression by estrogen in estrogen receptor-containing breast cancer cells via upstream half-palindromic estrogen response element motifsQ43679965
Domains of estrogen receptor alpha (ERalpha) required for ERalpha/Sp1-mediated activation of GC-rich promoters by estrogens and antiestrogens in breast cancer cellsQ44308496
Cell Context-Dependent Differences in the Induction of E2F-1 Gene Expression by 17β-Estradiol in MCF-7 and ZR-75 CellsQ44405062
Estrogen receptor α and Sp1 regulate progesterone receptor gene expressionQ44410591
Estrogen receptor/Sp1 complexes are required for induction of cad gene expression by 17beta-estradiol in breast cancer cellsQ44440498
The zinc finger repressor, ZBP-89, binds to the silencer element of the human vimentin gene and complexes with the transcriptional activator, Sp1.Q44871051
Characterization of the proximal estrogen-responsive element of human cathepsin D geneQ48082268
Sp4, a member of the Sp1-family of zinc finger transcription factors, is required for normal murine growth, viability, and male fertilityQ52201048
Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteinsQ52265963
c-Jun transactivates the promoter of the human p21(WAF1/Cip1) gene by acting as a superactivator of the ubiquitous transcription factor Sp1.Q52573384
Transcriptional activation of transforming growth factor alpha by estradiol: requirement for both a GC-rich site and an estrogen response element half-siteQ52579470
Multiple specific contacts between a mammalian transcription factor and its cognate promotersQ53747083
Hormone-induced Recruitment of Sp1 Mediates Estrogen Activation of the Rabbit Uteroglobin Gene in Endometrial EpitheliumQ53844450
Promoter targeting by adenovirus E1a through interaction with different cellular DNA-binding domains.Q54635804
Human Sug1/p45 is involved in the proteasome-dependent degradation of Sp1Q55884442
Vascular endothelial growth factors are differentially regulated by steroid hormones and antiestrogens in breast cancer cellsQ57382287
Transactivation via RAR/RXR-Sp1 Interaction: Characterization of Binding Between Sp1 and GC Box MotifQ58883688
Purification and biochemical characterization of the promoter-specific transcription factor, Sp1Q61942294
Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase IIQ64381020
Bidirectional SV40 transcription mediated by tandem Sp1 binding interactionsQ70103033
Nuclear receptor coactivatorsQ73153183
p300 collaborates with Sp1 and Sp3 in p21(waf1/cip1) promoter activation induced by histone deacetylase inhibitorQ73334469
Estrogen receptors alpha and beta form heterodimers on DNAQ73555536
Transcriptional repression of p21((Waf1/Cip1/Sdi1)) gene by c-jun through Sp1 siteQ73585916
Sp family members and nuclear factor-Y cooperatively stimulate transcription from the rat pyruvate kinase M gene distal promoter region via their direct interactionsQ73626525
An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitroQ77754902
Coregulatory proteins in nuclear hormone receptor actionQ78017200
Molecular mechanism for cooperation between Sp1 and steroidogenic factor-1 (SF-1) to regulate bovine CYP11A gene expressionQ78165328
CDK-independent activation of estrogen receptor by cyclin D1Q28304020
Molecular mechanism of inhibition of estrogen-induced cathepsin D gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in MCF-7 cellsQ28378735
Sp5, a new member of the Sp1 family, is dynamically expressed during development and genetically interacts with BrachyuryQ28508518
A novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineagesQ28510409
Transcription suppression of thromboxane receptor gene by peroxisome proliferator-activated receptor-gamma via an interaction with Sp1 in vascular smooth muscle cellsQ28580328
Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor betaQ28587815
The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigenQ28608938
TBP, a universal eukaryotic transcription factor?Q28626484
Molecular mechanisms of action of steroid/thyroid receptor superfamily membersQ29547540
Steroid hormone receptors: many actors in search of a plotQ29618397
Mechanism of transcriptional activation by Sp1: evidence for coactivatorsQ29620214
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motifQ29620290
The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoterQ29620405
Differential Ligand Activation of Estrogen Receptors ERα and ERβ at AP1 SitesQ29620551
Modulation of Sp1 activity by a cyclin A/CDK complexQ32124353
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's diseaseQ33292417
Transcriptional activation by Sp1 as directed through TATA or initiator: specific requirement for mammalian transcription factor IIDQ33630942
Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions.Q33694883
Nuclear receptor cofactors as chromatin remodelersQ33745092
Steroid/nuclear receptor coactivatorsQ33834146
Estrogen-responsive element of the human pS2 gene is an imperfectly palindromic sequenceQ33837377
Nuclear hormone receptor coregulators in action: diversity for shared tasksQ33857152
Functional interaction of NF-Y and Sp1 is required for type a natriuretic peptide receptor gene transcriptionQ33920484
Cross talk among calcineurin, Sp1/Sp3, and NFAT in control of p21(WAF1/CIP1) expression in keratinocyte differentiationQ33932993
Sp1 and krüppel-like factor family of transcription factors in cell growth regulation and cancerQ33952921
Histone deacetylase 1 can repress transcription by binding to Sp1.Q33958899
Determinants contributing to estrogen-regulated expression of SK3.Q34186294
Nuclear receptors in cell life and death.Q34432938
pRB induces Sp1 activity by relieving inhibition mediated by MDM2.Q34446511
Nuclear receptor coregulators: multiple modes of modificationQ34537625
Functional and physical interactions between the estrogen receptor Sp1 and nuclear aryl hydrocarbon receptor complexesQ34669282
A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activationQ34920038
Regulation of the activity of Sp1-related transcription factors.Q34922462
Quantitative studies of the effect of HTLV-I Tax protein on CREB protein--DNA bindingQ35010027
Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3.Q35267304
P304page(s)1-36
P577publication date2004-01-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inProgress in Molecular Biology and Translational ScienceQ15753415
P1476titleNuclear receptor-mediated transactivation through interaction with Sp proteins
P478volume77

Reverse relations

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