| scholarly article | Q13442814 |
| P356 | DOI | 10.1126/SCIENCE.3059495 |
| P8608 | Fatcat ID | release_2ivlhjyk25hw7gku7q7taxftea |
| P698 | PubMed publication ID | 3059495 |
| P2093 | author name string | Tjian R | |
| Kadonaga JT | |||
| Courey AJ | |||
| Ladika J | |||
| P433 | issue | 4885 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1566-1570 | |
| P577 | publication date | 1988-12-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Distinct regions of Sp1 modulate DNA binding and transcriptional activation | |
| P478 | volume | 242 |
| Q38313324 | A Drosophila homologue of human Sp1 is a head-specific segmentation gene. |
| Q24684723 | A Tat-induced auto-up-regulatory loop for superactivation of the human immunodeficiency virus type 1 promoter |
| Q33981133 | A cDNA from a mouse pancreatic beta cell encoding a putative transcription factor of the insulin gene |
| Q48336903 | A comprehensive collection of mouse zinc finger motifs compiled by molecular indexing |
| Q36714966 | A gene that encodes a protein consisting solely of zinc finger domains is preferentially expressed in transformed mouse cells |
| Q24811073 | A highly distinctive mechanical property found in the majority of human promoters and its transcriptional relevance |
| Q28507452 | A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1 |
| Q36676009 | A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter |
| Q36060628 | AHR promoter variant modulates its transcription and downstream effectors by allele-specific AHR-SP1 interaction functioning as a genetic marker for vitiligo |
| Q38344428 | Advances in molecular genetics of alpha-2- and alpha-3/4-fucosyltransferases. |
| Q44118164 | Altering DNA-binding specificity of GAL4 requires sequences adjacent to the zinc finger |
| Q41052367 | An Sp1-binding silencer element is a critical negative regulator of the megakaryocyte-specific alphaIIb gene |
| Q36666995 | An interaction between the DNA-binding domains of RelA(p65) and Sp1 mediates human immunodeficiency virus gene activation |
| Q38331066 | Analysis of promoter-specific repression by triple-helical DNA complexes in a eukaryotic cell-free transcription system |
| Q40422902 | Analysis of proteins binding to the proximal promoter region of the human cytomegalovirus IE-1/2 enhancer/promoter reveals both consensus and aberrant recognition sequences for transcription factors Sp1 and CREB. |
| Q39149869 | Anticancer activity of tolfenamic acid in medulloblastoma: a preclinical study. |
| Q42462030 | Basal expression of the gene (TIMP) encoding the murine tissue inhibitor of metalloproteinases is mediated through AP1- and CCAAT-binding factors |
| Q52447039 | Base sequence discrimination by zinc-finger DNA-binding domains. |
| Q34995160 | Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells |
| Q28131781 | Biochemistry and molecular cell biology of diabetic complications |
| Q36827796 | CTCF, a conserved nuclear factor required for optimal transcriptional activity of the chicken c-myc gene, is an 11-Zn-finger protein differentially expressed in multiple forms |
| Q47298461 | Caspase cleavage of transcription factor Sp1 enhances apoptosis |
| Q24650233 | Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction |
| Q33292406 | Cellular transcription factor Sp1 recruits simian virus 40 capsid proteins to the viral packaging signal, ses. |
| Q33782614 | Cellular transcription factors enhance herpes simplex virus type 1 oriS-dependent DNA replication. |
| Q39851281 | Characterization of sINR, a strict version of the Initiator core promoter element |
| Q41082090 | Characterization of the mouse junD promoter--high basal level activity due to an octamer motif |
| Q40963135 | Cleavage of transcription factor SP1 by caspases during anti-IgM-induced B-cell apoptosis |
| Q24629049 | Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes |
| Q24337872 | Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression |
| Q36807628 | Cloning of a negative transcription factor that binds to the upstream conserved region of Moloney murine leukemia virus |
| Q28278712 | Cloning, expression, sequence determination, and chromosome localization of the mouse complement C3a anaphylatoxin receptor gene |
| Q73745545 | Competition between iron(III)-selective chelators and zinc-finger domains for zinc(II) |
| Q50315355 | Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21WAF1/CIP1 during NGF-mediated neuronal differentiation |
| Q41557831 | Cooperative binding at a distance by even-skipped protein correlates with repression and suggests a mechanism of silencing |
| Q36686931 | Cooperative inhibition of NF-kappa B and Tat-induced superactivation of human immunodeficiency virus type 1 long terminal repeat |
| Q37114599 | Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity |
| Q39002684 | DNA looping and Sp1 multimer links: a mechanism for transcriptional synergism and enhancement |
| Q45715501 | DNA looping between sites for transcriptional activation: self-association of DNA-bound Sp1 |
| Q36802936 | Dephosphorylation of Sp1 by protein phosphatase 1 is involved in the glucose-mediated activation of the acetyl-CoA carboxylase gene |
| Q36683743 | Derivatives of Moloney murine sarcoma virus capable of being transcribed in embryonal carcinoma stem cells have gained a functional Sp1 binding site |
| Q58579972 | Diabetic Retinopathy: A complex pathophysiology requiring novel therapeutic strategies |
| Q37733102 | Dietary hyperglycemia, glycemic index and metabolic retinal diseases |
| Q38325118 | Differential sensitivity of transcription factors to mustard-damaged DNA. |
| Q38316296 | Direct interaction of the human cytomegalovirus IE86 protein with the cis repression signal does not preclude TBP from binding to the TATA box. |
| Q40628182 | Down-regulation of Sp1 activity through modulation of O-glycosylation by treatment with a low glucose mimetic, 2-deoxyglucose. |
| Q36336887 | Drosophila head segmentation factor buttonhead interacts with the same TATA box-binding protein-associated factors and in vivo DNA targets as human Sp1 but executes a different biological program |
| Q35185681 | Dynamic interplay between O-glycosylation and O-phosphorylation of nucleocytoplasmic proteins: a new paradigm for metabolic control of signal transduction and transcription |
| Q90362062 | Effects of in ovo injection of vitamin C on heat shock protein and metabolic genes expression |
| Q41647864 | Elements in the first intron of the alpha 1(I) collagen gene interact with Sp1 to regulate gene expression |
| Q38322068 | Epigenetic regulation of CD133/PROM1 expression in glioma stem cells by Sp1/myc and promoter methylation. |
| Q92626444 | Estradiol promotes the progression of ER+ breast cancer through methylation-mediated RSK4 inactivation |
| Q48051309 | Expression and regulation of the human and mouse aspartylglucosaminidase gene |
| Q35757943 | Expression of PACT is regulated by Sp1 transcription factor |
| Q34433280 | Expression of REX-1, a gene containing zinc finger motifs, is rapidly reduced by retinoic acid in F9 teratocarcinoma cells |
| Q38244917 | Function of transcription factors at DNA lesions in DNA repair |
| Q36644772 | Functional analysis of the V gamma 3 promoter of the murine gamma delta T-cell receptor |
| Q40016157 | Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF. |
| Q40489620 | Genes with triplet repeats: candidate mediators of neuropsychiatric disorders |
| Q28145050 | Genomic structure and chromosomal localization of the human hepatocyte growth factor activator inhibitor type 1 and 2 genes |
| Q42642223 | Genomic structure, transcriptional control, and tissue distribution of HERG1 and KCNQ1 genes |
| Q42158770 | Goblet-cell-specific transcription of mouse intestinal trefoil factor gene results from collaboration of complex series of positive and negative regulatory elements |
| Q33247390 | HMG1-related DNA-binding protein isolated with V-(D)-J recombination signal probes |
| Q74270274 | Heterogeneous Sp1 mRNAs in human HepG2 cells include a product of homotypic trans-splicing |
| Q56362150 | High-level Sp1 is Associated with Proliferation, Invasion, and Poor Prognosis in Astrocytoma |
| Q36627345 | Human papillomavirus type 11 E2 proteins repress the homologous E6 promoter by interfering with the binding of host transcription factors to adjacent elements. |
| Q27004438 | Hydrogen peroxide sensing, signaling and regulation of transcription factors |
| Q24682735 | Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation |
| Q38333213 | Identification and Characterization of Three DNA-binding Proteins on the Promoter of the Human MDRl Gene in Drug-sensitive and -resistant Cells |
| Q38339794 | Identification of a goblet cell-specific enhancer element in the rat intestinal trefoil factor gene promoter bound by a goblet cell nuclear protein |
| Q57979132 | Imaging dynamic and selective low-complexity domain interactions that control gene transcription |
| Q33342303 | Increased hepatic UCP2 expression in rats with nonalcoholic steatohepatitis is associated with upregulation of Sp1 binding to its motif within the proximal promoter region |
| Q38346668 | Induction of Sp1 activity by prolactin and interleukin-2 in Nb2 T-cells: differential association of Sp1-DNA complexes with Stats |
| Q38313075 | Induction of cellular genes is mediated by the Bel1 transactivator in foamy virus-infected human cells |
| Q53783735 | Interaction of Sp1 zinc finger with transport factor in the nuclear localization of transcription factor Sp1 |
| Q28291807 | Interaction of Virion Protein Vpr of Human Immunodeficiency Virus Type 1 with Cellular Transcription Factor Sp1 and trans-Activation of Viral Long Terminal Repeat |
| Q24645607 | Interaction of the v-Rel oncoprotein with cellular transcription factor Sp1 |
| Q42181095 | Interaction of transcription factor Sp1 with the promoter of the gene for the multifunctional protein disulphide isomerase polypeptide |
| Q39748079 | Interplay between REST and nucleolin transcription factors: a key mechanism in the overexpression of genes upon increased phosphorylation |
| Q48038003 | Involvement of Sp1 elements in the promoter activity of the alpha1-proteinase inhibitor gene |
| Q38352827 | Involvement of a high-mobility-group protein in the transcriptional activity of herpes simplex virus latency-active promoter 2. |
| Q33291003 | Lentiviral vectors encoding tetracycline-dependent repressors and transactivators for reversible knockdown of gene expression: a comparative study |
| Q34759832 | Macrophage-specific gene expression: current paradigms and future challenges |
| Q59811980 | MicroRNA-382 inhibits cell growth and migration in colorectal cancer by targeting SP1 |
| Q39375777 | MicroRNA: A novel target of curcumin in cancer therapy |
| Q49269166 | Mithramycin A suppresses basal triple-negative breast cancer cell survival partially via down-regulating Krüppel-like factor 5 transcription by Sp1. |
| Q34209261 | Mithramycin inhibits SP1 binding and selectively inhibits transcriptional activity of the dihydrofolate reductase gene in vitro and in vivo |
| Q71818074 | Mode of activation of the GC box/Spl-dependent promoter of the human NADH-cytochrome b5 reductase-encoding gene |
| Q33782959 | Modulation of Sp1 phosphorylation by human immunodeficiency virus type 1 Tat. |
| Q52553797 | Modulation of transcription factor Sp1 by cAMP-dependent protein kinase. |
| Q28587802 | Molecular cloning and characterization of a novel mouse macrophage gene that encodes a nuclear protein comprising polyglutamine repeats and interspersing histidines |
| Q31917763 | Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells. |
| Q73025186 | MyoD functions as a transcriptional repressor in proliferating myoblasts |
| Q24554518 | Myogenic basic helix-loop-helix proteins and Sp1 interact as components of a multiprotein transcriptional complex required for activity of the human cardiac alpha-actin promoter |
| Q33957454 | Neu differentiation factor stimulates phosphorylation and activation of the Sp1 transcription factor |
| Q28776202 | NonO, a non-POU-domain-containing, octamer-binding protein, is the mammalian homolog of Drosophila nonAdiss |
| Q34462072 | Nuclear and cytoplasmic glycosylation. |
| Q35805048 | Nuclear receptor-mediated transactivation through interaction with Sp proteins |
| Q24648205 | Nuclear respiratory factors 1 and 2 utilize similar glutamine-containing clusters of hydrophobic residues to activate transcription |
| Q28281931 | Nuclear targeting of the transcription factor PTF1 is mediated by a protein subunit that does not bind to the PTF1 cognate sequence |
| Q95651535 | Nuclear-mitochondrial communication involving miR-181c plays an important role in cardiac dysfunction during obesity |
| Q24644353 | O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions |
| Q24324116 | O-GlcNAc modification of Sp1 inhibits the functional interaction between Sp1 and Oct1 |
| Q24602222 | O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability |
| Q39887434 | O-linked N-acetylglucosaminylation of Sp1 inhibits the human immunodeficiency virus type 1 promoter |
| Q41665743 | Oncogenic germ-line mutations in Sp1 and ATF sites in the human retinoblastoma gene |
| Q38329050 | Only two of the five zinc fingers of the eukaryotic transcriptional repressor PRDI-BF1 are required for sequence-specific DNA binding |
| Q92966181 | Organization and regulation of gene transcription |
| Q35571285 | Overexpression of the transcription factor Sp1 activates the OAS-RNAse L-RIG-I pathway |
| Q35858003 | P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3. |
| Q70918081 | Patch clamp detection of transcription factor translocation along the nuclear pore complex channel |
| Q36534674 | Pharmacologic control of specific gene expression |
| Q37496666 | Post-translational control of sp-family transcription factors |
| Q34715657 | Proinflammatory stimuli control N-acylphosphatidylethanolamine-specific phospholipase D expression in macrophages |
| Q34663879 | Promoter characterization and role of cAMP/PKA/CREB in the basal transcription of the mouse ORMDL3 gene |
| Q36820638 | Promoter-specific transactivation of hepatitis B virus transcription by a glutamine- and proline-rich domain of hepatocyte nuclear factor 1 |
| Q36797816 | Properties of the DNA-binding domain of the simian virus 40 large T antigen |
| Q33842710 | Purification and analysis of RNA polymerase II transcription factors by using wheat germ agglutinin affinity chromatography |
| Q39322027 | Regulation of LRRK2 promoter activity and gene expression by Sp1. |
| Q34922462 | Regulation of the activity of Sp1-related transcription factors. |
| Q44866187 | Regulation of the estrogen receptor alpha minimal promoter by Sp1, USF-1 and ERalpha |
| Q28206102 | Regulation of the human cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1 |
| Q33494742 | Relationship between estrogen receptor alpha location and gene induction reveals the importance of downstream sites and cofactors |
| Q40022171 | Reversible activation of mouse metal response element-binding transcription factor 1 DNA binding involves zinc interaction with the zinc finger domain |
| Q48068590 | Role of a distal enhancer containing a functional NF-kappa B-binding site in lipopolysaccharide-induced expression of a novel alpha 1-antitrypsin gene |
| Q33499124 | SP1 enhances Zbtb7A gene expression via direct binding to GC box in HePG2 cells |
| Q42468752 | Sequence characterization and promoter identification of porcine APC10 gene |
| Q37535568 | Serum starvation-induced voltage-gated potassium channel Kv7.5 expression and its regulation by Sp1 in canine osteosarcoma cells |
| Q41176384 | Sp1 activates and inhibits transcription from separate elements in the proximal promoter of the human adenine nucleotide translocase 2 (ANT2) gene. |
| Q55304865 | Sp1 activation of RNA polymerase II transcription complexes involves a heat-labile DNA-binding component. |
| Q39722755 | Sp1 activation of a TATA-less promoter requires a species-specific interaction involving transcription factor IID. |
| Q24655353 | Sp1 and p73 activate PUMA following serum starvation |
| Q38267908 | Sp1 and the 'hallmarks of cancer'. |
| Q40744465 | Sp1 as G1 cell cycle phase specific transcription factor in epithelial cells |
| Q34349205 | Sp1 facilitates DNA double-strand break repair through a nontranscriptional mechanism |
| Q43628311 | Sp1 involvement in the 4beta-phorbol 12-myristate 13-acetate (TPA)-mediated increase in resistance to methotrexate in Chinese hamster ovary cells |
| Q38411011 | Sp1 is upregulated in human glioma, promotes MMP-2-mediated cell invasion and predicts poor clinical outcome |
| Q36792679 | Sp1 mediates glucose activation of the acetyl-CoA carboxylase promoter |
| Q43193517 | Sp1-mediated TRAIL induction in chemosensitization |
| Q45106628 | Sp1-mediated transcriptional activation from the dominant promoter of the rat alpha1B adrenergic receptor gene in DDT1MF-2 cells |
| Q33662360 | Sp2 is a maternally inherited transcription factor required for embryonic development |
| Q49443460 | Sp5 negatively regulates the proliferation of HCT116 cells by upregulating the transcription of p27. |
| Q36647515 | Species-specific interaction of the glutamine-rich activation domains of Sp1 with the TATA box-binding protein |
| Q41172880 | Specific targeting of protein-DNA complexes by DNA-reactive drugs (+)-CC-1065 and pluramycins |
| Q41279368 | Structural and functional analysis of the promoter of the murine V gamma 1.1 T cell receptor gene |
| Q39724600 | Structure and function of the human Werner syndrome gene promoter: evidence for transcriptional modulation |
| Q42467282 | Structure of the gene for the neuronal intermediate filament protein alpha-internexin and functional analysis of its promoter |
| Q27734986 | Structures of zinc finger domains from transcription factor Sp1. Insights into sequence-specific protein-DNA recognition |
| Q35779751 | Studying the recruitment of Sp1 to the beta-globin promoter with an in vivo method: protein position identification with nuclease tail (PIN*POINT) |
| Q35936421 | Targeting of Sp1 to a non-Sp1 site in the human neurofilament (H) promoter via an intermediary DNA-binding protein |
| Q34161703 | Tat and trans-activation-responsive (TAR) RNA-independent induction of HIV-1 long terminal repeat by human and murine cyclin T1 requires Sp1. |
| Q36636897 | The E2 transcriptional repressor can compensate for Sp1 activation of the human papillomavirus type 18 early promoter |
| Q34493766 | The Nature, Extent, and Consequences of Genetic Variation in the opa Repeats of Notch in Drosophila |
| Q38299132 | The erythroid Krüppel-like factor transactivation domain is a critical component for cell-specific inducibility of a beta-globin promoter |
| Q24303815 | The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins |
| Q36689138 | The functional domains of the murine Thy-1 gene promoter |
| Q36567115 | The glutamine-rich activation domains of human Sp1 do not stimulate transcription in Saccharomyces cerevisiae. |
| Q42862247 | The human carbonic anhydrase I gene has two promoters with different tissue specificities |
| Q40816643 | The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages |
| Q28364217 | The potential mechanism of the diabetogenic action of streptozotocin: inhibition of pancreatic beta-cell O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase |
| Q24522845 | The promyelocytic leukemia protein interacts with Sp1 and inhibits its transactivation of the epidermal growth factor receptor promoter |
| Q36816438 | The retinoblastoma gene product regulates Sp1-mediated transcription |
| Q33919366 | The segment-specific gene Krox-20 encodes a transcription factor with binding sites in the promoter region of the Hox-1.4 gene |
| Q36643168 | The sua8 suppressors of Saccharomyces cerevisiae encode replacements of conserved residues within the largest subunit of RNA polymerase II and affect transcription start site selection similarly to sua7 (TFIIB) mutations |
| Q35632879 | Tissue-specific activity of the blind mole rat and the two nucleotide-mutated mouse alphaB-crystallin promoter in transgenic mice |
| Q38345845 | Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation |
| Q36733082 | Transcription factor Sp1 is important for retinoic acid-induced expression of the tissue plasminogen activator gene during F9 teratocarcinoma cell differentiation |
| Q36717640 | Transcription initiation from the dihydrofolate reductase promoter is positioned by HIP1 binding at the initiation site |
| Q33945727 | Transcription of mouse Sp2 yields alternatively spliced and sub-genomic mRNAs in a tissue- and cell-type-specific fashion |
| Q34620520 | Transcriptional activation by stimulating protein 1 and post-transcriptional repression by muscle-specific microRNAs of IKs-encoding genes and potential implications in regional heterogeneity of their expressions |
| Q40501283 | Transcriptional activity of serum amyloid A-activating factor-1 is regulated by distinct functional modules |
| Q36832439 | Transcriptional analysis of minute virus of mice P4 promoter mutants |
| Q40819590 | Transcriptional enhancement by upstream activators is brought about by different molecular mechanisms for class I and II RNA polymerase genes |
| Q34181426 | Transcriptional regulation of N-acetylglutamate synthase. |
| Q41130803 | Transcriptional regulation of neurofilament expression by protein kinase A. |
| Q38346842 | Transcriptional regulatory regions for expression of the rat fatty acid synthase |
| Q41196528 | Tumor-suppressing effects of microRNA-429 in human renal cell carcinoma via the downregulation of Sp1. |
| Q27934951 | Two monomers of yeast transcription factor ADR1 bind a palindromic sequence symmetrically to activate ADH2 expression |
| Q89682289 | Understanding the Role of the Transcription Factor Sp1 in Ovarian Cancer: from Theory to Practice |
| Q82038976 | Zac1, an Sp1-like protein, regulates human p21(WAF1/Cip1) gene expression in HeLa cells |
| Q91694233 | miR-181c Activates Mitochondrial Calcium Uptake by Regulating MICU1 in the Heart |
| Q37297592 | miRNA-411 acts as a potential tumor suppressor miRNA via the downregulation of specificity protein 1 in breast cancer |
| Q35855782 | ras oncogene-dependent activation of the P4 promoter of minute virus of mice through a proximal P4 element interacting with the Ets family of transcription factors. |
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