The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulator

scientific article published on July 1994

The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulator is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.14.7.4380
P932PMC publication ID358809
P698PubMed publication ID8007947

P2093author name stringK Yokoyama
R Chiu
K Kwan
L I Chen
Y H Fu
T Nishinaka
I Kitabayashi
S Grünwald
P2860cites workE1A dependent up-regulation of c-jun/AP-1 activityQ40531229
Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinaseQ41080352
Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cellsQ41407134
A synergistic increase in potency of a multimerized VP16 transcriptional activation domainQ41543585
Oncogenic germ-line mutations in Sp1 and ATF sites in the human retinoblastoma geneQ41665743
Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcriptionQ41684614
GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinaseQ41718635
Negative regulation of human c-fos expression by the retinoblastoma gene productQ41724715
SV40 stimulates expression of the transacting factor Sp1 at the mRNA levelQ41738735
The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T.Q41744248
The retinoblastoma gene product suppresses neu oncogene-induced transformation via transcriptional repression of neuQ42819290
Induction of proto-oncogene JUN/AP-1 by serum and TPA.Q43487125
Prolonged activation of jun and collagenase genes by tumour necrosis factor-alphaQ43819767
Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiationQ46219366
Common DNA binding site for Fos protein complexesand transcription factor AP-1Q57963290
Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblastsQ59095246
A common set of nuclear factors bind to promoter elements regulated by the retinoblastoma proteinQ67918108
Structural rearrangement of the retinoblastoma gene in human breast carcinomaQ67942728
Stability of retinoblastoma gene expression determines the tumorigenicity of reconstituted retinoblastoma cellsQ68017237
The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory elementQ69535058
Interleukin-1 costimulatory activity on the interleukin-2 promoter via AP-1Q69763276
Altered expression of the retinoblastoma (RB) gene in small-cell carcinoma of the lungQ69855061
Chromosomal reorganization for the expression of recessive mutation of retinoblastoma susceptibility gene in the development of osteosarcomaQ69919544
DNA sequencing with chain-terminating inhibitorsQ22066207
jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-junQ24302170
Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expressionQ24337872
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cellsQ27860607
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factorQ28288345
The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genesQ28291126
Retinoblastoma gene product activates expression of the human TGF-β2 gene through transcription factor ATF-2Q28291493
GAL4-VP16 is an unusually potent transcriptional activatorQ29616453
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcomaQ29618817
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motifQ29620290
The E2F transcription factor is a cellular target for the RB proteinQ29620422
A vector for expressing GAL4(1-147) fusions in mammalian cellsQ29620516
Some retinoblastomas, osteosarcomas, and soft tissue sarcomas may share a common etiologyQ33562563
Induction of protooncogene c-jun by serum growth factorsQ33669993
Abnormalities in structure and expression of the human retinoblastoma gene in SCLC.Q33825340
Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinomaQ33829814
Deregulated expression of human c-jun transforms primary rat embryo cells in cooperation with an activated c-Ha-ras gene and transforms rat-1a cells as a single geneQ33846819
Transcriptional regulation of the c-jun gene by retinoic acid and E1A during differentiation of F9 cellsQ33937271
Structure and expression of the murine retinoblastoma gene and characterization of its encoded proteinQ34299480
The retinoblastoma protein is phosphorylated during specific phases of the cell cycleQ34507572
Sp-1 binds promoter elements regulated by the RB protein and Sp-1-mediated transcription is stimulated by RB coexpressionQ36234059
The retinoblastoma gene product regulates Sp1-mediated transcriptionQ36816438
12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking regionQ36842600
Regulation of transforming growth factor beta 1 gene expression by the product of the retinoblastoma-susceptibility geneQ37474961
Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene productQ37622299
Regulation of the Ets-related transcription factor Elf-1 by binding to the retinoblastoma proteinQ38319003
The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2FQ38334818
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectretinoblastomaQ500695
P304page(s)4380-4389
P577publication date1994-07-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleThe retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulator
P478volume14

Reverse relations

cites work (P2860)
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