| scholarly article | Q13442814 |
| P2093 | author name string | Kraft AS | |
| Kudlow JE | |||
| Biggs JR | |||
| P2860 | cites work | The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases | Q24319848 |
| Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression | Q24337872 | ||
| WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
| Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alpha: signal-induced phosphorylation of I kappa B-alpha alone does not release active NF-kappa B | Q28615810 | ||
| A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells | Q29547557 | ||
| Transcriptional activation: a complex puzzle with few easy pieces | Q29616518 | ||
| Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif | Q29620290 | ||
| Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism | Q34235866 | ||
| A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation | Q34920038 | ||
| Sp-1 binds promoter elements regulated by the RB protein and Sp-1-mediated transcription is stimulated by RB coexpression | Q36234059 | ||
| 5-Azacytidine treatment of HA-A melanoma cells induces Sp1 activity and concomitant transforming growth factor alpha expression | Q36700438 | ||
| The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulator | Q38306731 | ||
| p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells | Q41368682 | ||
| Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. | Q41368691 | ||
| Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin | Q41412030 | ||
| p21-containing cyclin kinases exist in both active and inactive states | Q41451975 | ||
| Induction of differentiation and c‐jun expression in human leukemic cells by okadaic acid, an inhibitor of protein phosphatases | Q41627661 | ||
| GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase | Q41718635 | ||
| Largest subunit of Drosophila transcription factor IID directs assembly of a complex containing TBP and a coactivator. | Q44826917 | ||
| p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. | Q45993768 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | leukemia | Q29496 |
| P304 | page(s) | 901-906 | |
| P577 | publication date | 1996-01-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | The role of the transcription factor Sp1 in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells | |
| P478 | volume | 271 |
| Q38363872 | 3,3'-Diindolylmethane (DIM) induces a G(1) cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21(WAF1/CIP1) expression |
| Q38318551 | A Sp1 binding site of the tumor necrosis factor alpha promoter functions as a nitric oxide response element |
| Q39529595 | Activation of HTLV-I Long Terminal Repeat by Stress-Inducing Agents and Protection of HTLV-I-Infected T-cells from Apoptosis by the Viral Tax Protein |
| Q40975184 | Activation of Sp1 and its functional co-operation with serum amyloid A-activating sequence binding factor in synoviocyte cells trigger synergistic action of interleukin-1 and interleukin-6 in serum amyloid A gene expression |
| Q43734019 | Activation of p21(WAF1/Cip1) transcription through Sp1 sites by histone deacetylase inhibitor apicidin: involvement of protein kinase C. |
| Q31750307 | Activation of the p21WAF1/CIP1 promoter independent of p53 by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through the Sp1 sites |
| Q47821155 | Acute Promyelocytic Leukemia as a Model for Cross-Talk Between Interferon and Retinoic Acid Pathways: From Molecular Biology to Clinical Applications |
| Q73561893 | An IFN regulatory factor-2 DNA-binding domain dominant negative mutant exhibits altered cell growth and gene expression |
| Q34181572 | BCR-ABL but Not JAK2 V617F Inhibits Erythropoiesis through the Ras Signal by Inducing p21CIP1/WAF1 |
| Q41092576 | Butyrate Activates the WAF1/Cip1 Gene Promoter through Sp1 Sites in a p53-negative Human Colon Cancer Cell Line |
| Q38761317 | C3 exoenzyme impairs cell proliferation and apoptosis by altering the activity of transcription factors |
| Q42481241 | CCL18-stimulated upregulation of collagen production in lung fibroblasts requires Sp1 signaling and basal Smad3 activity |
| Q41016881 | Cell Cycle‐dependent Modulation of Promoter Activities of RB and WAF1/Cip1 Genes |
| Q38333792 | Cell-type-specific transcription factor interactions with cis-elements present in the mouse LDH/C proximal promoter region |
| Q31131003 | Characterization of the neuropilin-1 promoter; gene expression is mediated by the transcription factor Sp1. |
| Q53210602 | Cladosporol a stimulates G1-phase arrest of the cell cycle by up-regulation of p21(waf1/cip1) expression in human colon carcinoma HT-29 cells |
| Q30855520 | Cleavage of p21/WAF1/CIP1 by proteinase 3 modulates differentiation of a monocytic cell line. Molecular analysis of the cleavage site. |
| Q28587198 | Cloning and partial characterization of the mouse glutamine:fructose-6-phosphate amidotransferase (GFAT) gene promoter |
| Q50315355 | Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21WAF1/CIP1 during NGF-mediated neuronal differentiation |
| Q35248527 | Cyproheptadine, an antihistaminic drug, inhibits proliferation of hepatocellular carcinoma cells by blocking cell cycle progression through the activation of P38 MAP kinase |
| Q34325742 | Cytosolic retention of phosphorylated extracellular signal-regulated kinase and a Rho-associated kinase-mediated signal impair expression of p21(Cip1/Waf1) in phorbol 12-myristate-13- acetate-induced apoptotic cells |
| Q40903617 | Differential role for Sp1/Sp3 transcription factors in the regulation of the promoter activity of multiple cyclin-dependent kinase inhibitor genes |
| Q40628182 | Down-regulation of Sp1 activity through modulation of O-glycosylation by treatment with a low glucose mimetic, 2-deoxyglucose. |
| Q33285072 | Down-regulation of human topoisomerase IIalpha expression correlates with relative amounts of specificity factors Sp1 and Sp3 bound at proximal and distal promoter regions |
| Q40428841 | Down-regulation of peroxisome proliferator-activated receptor gamma in human cervical carcinoma |
| Q34534800 | Dual effects of hepatitis C virus Core protein on the transcription of cyclin-dependent kinase inhibitor p21 gene. |
| Q42448762 | Follicle Stimulating Hormone-Regulated Expression of Serum/Glucocorticoid-Inducible Kinase in Rat Ovarian Granulosa Cells: A Functional Role for the Sp1 Family in Promoter Activity |
| Q33706929 | Functional role of p21 during the cellular response to stress. |
| Q90590903 | Genistein inhibits proliferation and induces senescence in neonatal mouse pituitary gland explant cultures |
| Q40797473 | Growth inhibitory effect of p21 and p53 containing adenoviruses on transitional cell carcinoma cell lines in vitro and in vivo. |
| Q22254707 | Hepatitis B virus-X protein upregulates the expression of p21waf1/cip1 and prolongs G1-->S transition via a p53-independent pathway in human hepatoma cells |
| Q24554331 | HuR regulates p21 mRNA stabilization by UV light |
| Q54765380 | Hyperoxia induces macrophage cell cycle arrest by adhesion-dependent induction of p21Cip1 and activation of the retinoblastoma protein. |
| Q43690447 | Identification of a phorbol ester-responsive element in the interferon-gamma receptor 1 chain gene |
| Q35075466 | Identification of poly(ADP-ribose) polymerase-1 as a cell cycle regulator through modulating Sp1 mediated transcription in human hepatoma cells |
| Q40796947 | Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells |
| Q46589925 | Induction of growth inhibition and apoptosis in human uterine leiomyoma cells by isoliquiritigenin |
| Q74194228 | Induction of p21WAF1 expression via Sp1-binding sites by tamoxifen in estrogen receptor-negative lung cancer cells |
| Q41039370 | Inhibition of the 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Pathway Induces p53-independent Transcriptional Regulation of p21 in Human Prostate Carcinoma Cells |
| Q38348517 | Insulin-Like Growth Factor I Increases Rat Peptide YY Promoter Activity through Sp1 Binding Sites |
| Q40593611 | Integrin beta1 subunit overexpressed in the SMMC-7721 cells regulates the promoter activity of p21(CIP1) and enhances its transcription. |
| Q24532825 | Interaction of human thymidine kinase 1 with p21(Waf1) |
| Q24300739 | Interferon Regulatory Factor 1 (IRF-1) induces p21(WAF1/CIP1) dependent cell cycle arrest and p21(WAF1/CIP1) independent modulation of survivin in cancer cells |
| Q42528762 | Involvement of the Sp3 transcription factor in induction of p21Cip1/WAF1 in keratinocyte differentiation |
| Q41601708 | Linking Protein Kinase C to Cell‐Cycle Control |
| Q42264631 | Modulation of DNA topoisomerase II alpha promoter activity by members of the Sp (specificity protein) and NF-Y (nuclear factor Y) families of transcription factors |
| Q43553555 | Modulation of cell cycle-related protein expression by sodium butyrate in human non-small cell lung cancer cell lines |
| Q24316065 | Molecular Cloning and Characterization of TIEG2Reveals a New Subfamily of Transforming Growth Factor-β-inducible Sp1-like Zinc Finger-encoding Genes Involved in the Regulation of Cell Growth |
| Q40234882 | Molecular mechanism of adaphostin-mediated G1 arrest in prostate cancer (PC-3) cells: signaling events mediated by hepatocyte growth factor receptor, c-Met, and p38 MAPK pathways |
| Q26775592 | Motif co-regulation and co-operativity are common mechanisms in transcriptional, post-transcriptional and post-translational regulation |
| Q59098609 | Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage |
| Q43710107 | N-acetylcysteine induces cell cycle arrest in hepatic stellate cells through its reducing activity |
| Q33833014 | Natural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene |
| Q41094353 | Nerve Growth Factor Induces Transcription of the p21 WAF1/CIP1 and Cyclin D1 Genes in PC12 Cells by Activating the Sp1 Transcription Factor |
| Q33957454 | Neu differentiation factor stimulates phosphorylation and activation of the Sp1 transcription factor |
| Q63561082 | New compound ChlA-F induces autophagy-dependent anti-cancer effect via upregulating Sestrin-2 in human bladder cancer |
| Q34227734 | Overexpression of HMGB1 in melanoma predicts patient survival and suppression of HMGB1 induces cell cycle arrest and senescence in association with p21 (Waf1/Cip1) up-regulation via a p53-independent, Sp1-dependent pathway |
| Q40173700 | PI 3-K signaling pathway suppresses PMA-induced expression of p21WAF1/Cip1 in human leukemia cells |
| Q40603112 | Participation of p97Eps8 in Src-mediated transformation |
| Q92260725 | Polymorphism rs2395655 affects LEDGF/p75 binding activity and p21WAF1/CIP1 gene expression in esophageal squamous cell carcinoma |
| Q42454022 | Progesterone Regulates Transcription of the p21 Cyclindependent Kinase Inhibitor Gene through Sp1 and CBP/p300 |
| Q77518989 | Promoter activation and following induction of the p21/WAF1 gene by flavone is involved in G1 phase arrest in A549 lung adenocarcinoma cells |
| Q47984119 | Promoter-specific p53-dependent histone acetylation following DNA damage |
| Q74298189 | Protein kinase C α modulates growth and differentiation in Caco-2 cells |
| Q36710187 | Protein kinase Calpha-induced derepression of the human luteinizing hormone receptor gene transcription through ERK-mediated release of HDAC1/Sin3A repressor complex from Sp1 sites |
| Q73787725 | RB regulates transcription of the p21/WAF1/CIP1 gene |
| Q44187434 | Rapid detection of apoptosis through real-time reverse transcriptase polymerase chain reaction measurement of the small cytoplasmic RNA Y1. |
| Q38317596 | Ras induces p21Cip1/Waf1 cyclin kinase inhibitor transcriptionally through Sp1-binding sites |
| Q59297312 | Redox-Mediated Regulation of p21Waf1/Cip1 Expression Involves a Post-Transcriptional Mechanism and Activation of the Mitogen-Activated Protein Kinase Pathway |
| Q36983415 | Redox-regulation of Erk1/2-directed phosphatase by reactive oxygen species: role in signaling TPA-induced growth arrest in ML-1 cells |
| Q36568052 | Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility |
| Q40650133 | Regulation of human CETP gene expression: role of SP1 and SP3 transcription factors at promoter sites -690, -629, and -37. |
| Q33871779 | Regulation of myelin basic protein gene transcription by Sp1 and Puralpha: evidence for association of Sp1 and Puralpha in brain |
| Q36486862 | Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members |
| Q64086789 | Regulatory mechanisms of fluvastatin and lovastatin for the p21 induction in human cervical cancer HeLa cells |
| Q44549000 | Role of protein kinase C and the Sp1-p53 complex in activation of p21(WAF-1) expression by 12-O-tetradecanoylphorbol-13-acetate in human T cells |
| Q38569361 | Role of the translational repressor 4E-BP1 in the regulation of p21(Waf1/Cip1) expression by retinoids |
| Q40858901 | Sodium butyrate modulates cell cycle-related proteins in HT29 human colonic adenocarcinoma cells |
| Q40844112 | Sp1 and Sp3 activate p21 (WAF1/CIP1) gene transcription in the Caco-2 colon adenocarcinoma cell line |
| Q38355603 | Sp1 and Sp3 are involved in up-regulation of human deoxyribonuclease II transcription during differentiation of HL-60 cells. |
| Q38267908 | Sp1 and the 'hallmarks of cancer'. |
| Q43628311 | Sp1 involvement in the 4beta-phorbol 12-myristate 13-acetate (TPA)-mediated increase in resistance to methotrexate in Chinese hamster ovary cells |
| Q38300297 | Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein |
| Q42820210 | Sp1 transcriptional activity is up-regulated by phosphatase 2A in dividing T lymphocytes |
| Q40759850 | Sp3 Represses Gene Expression via the Titration of Promoter-specific Transcription Factors |
| Q34632672 | Sp3 encodes multiple proteins that differ in their capacity to stimulate or repress transcription |
| Q34523902 | Subcellular localization of HCV core protein regulates its ability for p53 activation and p21 suppression |
| Q44426868 | TPA activates p21WAF-1 promoter in human T-cells through its second most upstream Sp1 site |
| Q24529076 | TReP-132 controls cell proliferation by regulating the expression of the cyclin-dependent kinase inhibitors p21WAF1/Cip1 and p27Kip1 |
| Q24310788 | The Gfi-1B Proto-Oncoprotein Represses p21WAF1 and Inhibits Myeloid Cell Differentiation |
| Q92783649 | The Multifaceted p21 (Cip1/Waf1/CDKN1A) in Cell Differentiation, Migration and Cancer Therapy |
| Q42515347 | The critical role of the PE21 element in oncostatin M-mediated transcriptional repression of the p53 tumor suppressor gene in breast cancer cells |
| Q34614124 | The cyclooxygenase inhibitor sulindac sulfide inhibits EP4 expression and suppresses the growth of glioblastoma cells |
| Q24653488 | The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter |
| Q24533294 | The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21WAF1/CIP1/SDI1 in S phase |
| Q40959304 | The mycotoxin fumonisin B1 transcriptionally activates the p21 promoter through a cis-acting element containing two Sp1 binding sites |
| Q34212168 | The p21-Dependent Radiosensitization of Human Breast Cancer Cells by MLN4924, an Investigational Inhibitor of NEDD8 Activating Enzyme |
| Q39762792 | The transcription factor SP1 regulates centriole function and chromosomal stability through a functional interaction with the mammalian target of rapamycin/raptor complex. |
| Q40022229 | Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21(WAF1/Cip1) by STAT5 |
| Q73884552 | Transcription factors ets1, NF-kappa B, and Sp1 are major determinants of the promoter activity of the human protein kinase CK2alpha gene |
| Q77593716 | Transcriptional coordination of the genes encoding catalytic (CK2alpha) and regulatory (CK2beta) subunits of human protein kinase CK2 |
| Q35225482 | Transcriptional regulation of the cyclin-dependent kinase inhibitor 1A (p21) gene by NFI in proliferating human cells |
| Q42825156 | Transcriptional repression of p21(waf1) promoter by hepatitis B virus X protein via a p53-independent pathway |
| Q42051240 | Transient downregulation of protein O-N-acetylglucosaminylation by treatment of high-dose nicotinamide in human cells |
| Q38602505 | Unique induction of p21WAF1/CIP1expression by vinorelbine in androgen-independent prostate cancer cells |
| Q40689721 | Vesnarinone, a differentiation inducing drug, directly activates p21(waf1) gene promoter via Sp1 sites in a human salivary gland cancer cell line |
| Q40478048 | Visible light exposure induces VEGF gene expression through activation of retinoic acid receptor-alpha in retinoblastoma Y79 cells. |
| Q40405318 | Zinc finger transcription factor Egr-1 is involved in stimulation of NHE2 gene expression by phorbol 12-myristate 13-acetate |
| Q40020060 | p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage. |
| Q59310824 | p21(cip1) mRNA is controlled by endogenous transforming growth factor-beta1 in quiescent human hematopoietic stem/progenitor cells |
| Q40979144 | p21WAF1 expression by an activator of protein kinase C is regulated mainly at the post-transcriptional level in cells lacking p53: important role of RNA stabilization |
| Q92422648 | p21cip1/waf1 Coordinate Autophagy, Proliferation and Apoptosis in Response to Metabolic Stress |
| Q39677755 | p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinase |
| Q41014337 | p53-independent induction of WAF1/Cip1 is correlated with osteoblastic differentiation by vitamin D3 |
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