| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1050164849 |
| P356 | DOI | 10.1038/NATURE01119 |
| P698 | PubMed publication ID | 12384701 |
| P50 | author | Joan Massagué Solé | Q462775 |
| Joan Seoane | Q24055168 | ||
| P2093 | author name string | Hong-Van Le | |
| P2860 | cites work | OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways | Q22011195 |
| An alternative pathway for gene regulation by Myc | Q24532791 | ||
| WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
| Surfing the p53 network | Q28032484 | ||
| The Myc/Max/Mad network and the transcriptional control of cell behavior | Q28141143 | ||
| TGFbeta signaling in growth control, cancer, and heritable disorders | Q28142605 | ||
| Repression of p15INK4b expression by Myc through association with Miz-1 | Q28210023 | ||
| Transcription factor MIZ-1 is regulated via microtubule association | Q28215644 | ||
| Human Smad3 and Smad4 are sequence-specific transcription activators | Q28276193 | ||
| Live or let die: the cell's response to p53 | Q29547663 | ||
| Requirement for p53 and p21 to sustain G2 arrest after DNA damage | Q29547667 | ||
| Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription | Q29547846 | ||
| Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization | Q29614701 | ||
| A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin | Q33540751 | ||
| Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1. | Q34425853 | ||
| Identification of a novel class of genomic DNA-binding sites suggests a mechanism for selectivity in target gene activation by the tumor suppressor protein p53 | Q35205701 | ||
| A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest | Q35207580 | ||
| Transforming Growth Factor β Activates the Promoter of Cyclin-dependent Kinase Inhibitor p15 through an Sp1 Consensus Site | Q38289403 | ||
| TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b | Q39420254 | ||
| Myc downregulation by transforming growth factor beta required for activation of the p15(Ink4b) G(1) arrest pathway. | Q39446946 | ||
| Methylation silencing and mutations of the p14ARF and p16INK4a genes in colon cancer | Q40822748 | ||
| The role of the transcription factor Sp1 in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells | Q41239623 | ||
| Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter | Q41267630 | ||
| Genetic determinants of p53-induced apoptosis and growth arrest | Q42812233 | ||
| AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression | Q45345486 | ||
| How cells choose to die | Q59091869 | ||
| Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta | Q71995235 | ||
| P433 | issue | 6908 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 729-734 | |
| P577 | publication date | 2002-10-02 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage | |
| P478 | volume | 419 |
| Q40507373 | A RasGAP-derived cell permeable peptide potently enhances genotoxin-induced cytotoxicity in tumor cells |
| Q24305959 | A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells |
| Q37229105 | A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis. |
| Q81232076 | A new mode of transcriptional repression by c-myc: methylation |
| Q35536232 | A novel knowledge-driven systems biology approach for phenotype prediction upon genetic intervention |
| Q33997195 | A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma |
| Q79773933 | A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition |
| Q28910214 | A ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growth |
| Q24301395 | A role of Miz-1 in Gfi-1-mediated transcriptional repression of CDKN1A |
| Q34193296 | A self-enabling TGFbeta response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells. |
| Q99350008 | A small molecular compound CC1007 induces cross-lineage differentiation by inhibiting HDAC7 expression and HDAC7/MEF2C interaction in BCR-ABL1- pre-B-ALL |
| Q53656452 | A-Miz-ing BCL6. |
| Q24297172 | AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis |
| Q24316196 | AP4 encodes a c-MYC-inducible repressor of p21 |
| Q34994378 | Acute overexpression of Myc in intestinal epithelium recapitulates some but not all the changes elicited by Wnt/beta-catenin pathway activation |
| Q33209569 | Akt and 14-3-3eta regulate Miz1 to control cell-cycle arrest after DNA damage |
| Q38354644 | Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression |
| Q47259237 | Analysis of genomic targets reveals complex functions of MYC. |
| Q33336561 | Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM |
| Q39588949 | Antitumor activity of erythromycin on human neuroblastoma cell line (SH-SY5Y). |
| Q44751341 | Anything but simple: a phosphorylation-driven toggle within Brd4 triggers gene-specific transcriptional activation. |
| Q35915905 | Apoptosis and colorectal cancer |
| Q37679253 | Apoptotic cell death in neuroblastoma |
| Q37310199 | Apoptotic signaling by c-MYC. |
| Q34042035 | BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer |
| Q40377462 | BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells |
| Q28269301 | BET domain co-regulators in obesity, inflammation and cancer |
| Q53155142 | BNIP3L-dependent mitophagy accounts for mitochondrial clearance during 3 factors-induced somatic cell reprogramming. |
| Q35082715 | Balance of Yin and Yang: ubiquitylation-mediated regulation of p53 and c-Myc |
| Q39256854 | CRM1 blockade by selective inhibitors of nuclear export attenuates kidney cancer growth |
| Q53662195 | Cancer: two in one. |
| Q37054884 | Carrot and stick: HIF-alpha engages c-Myc in hypoxic adaptation |
| Q37743042 | Cdk2: a key regulator of the senescence control function of Myc. |
| Q35299697 | Cell cycle regulation: repair and regeneration in acute renal failure |
| Q39054155 | Characterisation of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows conservation of regulating transcription factor networks |
| Q28184455 | Characterization of the murine Nramp1 promoter: requirements for transactivation by Miz-1 |
| Q35833204 | Circadian genes Per1 and Per2 increase radiosensitivity of glioma in vivo |
| Q37263298 | Computational analysis of dynamical responses to the intrinsic pathway of programmed cell death |
| Q58779438 | Constitutive activation and overexpression of NF-κB/c-Rel in conjunction with p50 contribute to aggressive tongue tumorigenesis |
| Q35603381 | Control of apoptosis by p53. |
| Q28581842 | Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19ARF-p53 pathway |
| Q34523124 | Crude aqueous extracts of Pluchea indica (L.) Less. inhibit proliferation and migration of cancer cells through induction of p53-dependent cell death. |
| Q54528529 | Cyclin E drives human keratinocyte growth into differentiation. |
| Q38995523 | Cyclin-Dependent Kinase Inhibitor-1-Deficient Mice are Susceptible to Osteoarthritis Associated with Enhanced Inflammation. |
| Q40400655 | Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells. |
| Q42033706 | Cyclin‑dependent kinase inhibitor p21 does not impact embryonic endochondral ossification in mice. |
| Q29616379 | Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer |
| Q24303568 | DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth |
| Q37634889 | DDB2 (damaged-DNA binding protein 2) in nucleotide excision repair and DNA damage response |
| Q37249918 | DDB2 decides cell fate following DNA damage |
| Q35208818 | DNA damage checkpoint control in cells exposed to ionizing radiation |
| Q39424192 | DNA-PKCS binding to p53 on the p21WAF1/CIP1 promoter blocks transcription resulting in cell death. |
| Q34439113 | Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels |
| Q30436741 | Deregulation of c-Myc Confers distinct survival requirements for memory B cells, plasma cells, and their progenitors |
| Q33898309 | Determination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemia |
| Q35128451 | Differential cooperation of oncogenes with p53 and Bax to induce apoptosis in rhabdomyosarcoma |
| Q35214619 | Differential effects of cell cycle regulatory protein p21(WAF1/Cip1) on apoptosis and sensitivity to cancer chemotherapy |
| Q24338676 | Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis |
| Q64956138 | Discussion of some 'knowns' and some 'unknowns' about the tumour suppressor p53. |
| Q39811977 | Disruption of the Pdcd4 tumor suppressor gene in chicken DT40 cells reveals its role in the DNA-damage response |
| Q39848157 | Dissection of the sequence-specific DNA binding and exonuclease activities reveals a superactive yet apoptotically impaired mutant p53 protein |
| Q40428137 | Dormant Pluripotent Cells Emerge during Neural Differentiation of Embryonic Stem Cells in a FoxO3-Dependent Manner |
| Q34068131 | E3 ubiquitin ligase Mule ubiquitinates Miz1 and is required for TNFalpha-induced JNK activation |
| Q35784734 | EBNA2 interferes with the germinal center phenotype by downregulating BCL6 and TCL1 in non-Hodgkin's lymphoma cells |
| Q44653675 | Effects of Helicobacter pylori CagA protein on the growth and survival of B lymphocytes, the origin of MALT lymphoma |
| Q39353575 | Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo |
| Q35975127 | Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy |
| Q36823545 | Enhanced beta cell proliferation in mice overexpressing a constitutively active form of Akt and one allele of p21Cip. |
| Q40612645 | Enhanced expression of MYCN leads to centrosome hyperamplification after DNA damage in neuroblastoma cells |
| Q34115503 | Epstein-Barr virus nuclear antigen 3A protein regulates CDKN2B transcription via interaction with MIZ-1 |
| Q33223556 | Equivalent effect of DNA damage-induced apoptotic cell death or long-term cell cycle arrest on colon carcinoma cell proliferation and tumour growth |
| Q39317652 | Evaluation and Elucidation Studies of Natural Aglycones for Anticancer Potential using Apoptosis-Related Markers: An In silico Study |
| Q36142180 | Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants |
| Q27692024 | Examination of the expanding pathways for the regulation of p21 expression and activity |
| Q36308627 | Expression of MTLC gene in gastric carcinoma |
| Q24319845 | FOXP3 up-regulates p21 expression by site-specific inhibition of histone deacetylase 2/histone deacetylase 4 association to the locus |
| Q37492244 | Facilitating replication under stress: an oncogenic function of MYC? |
| Q50317843 | Fam60al as a novel factor involved in reprogramming of somatic cell nuclear transfer in zebrafish (Danio rerio). |
| Q39454070 | Family matters: How MYC family oncogenes impact small cell lung cancer. |
| Q53173608 | From oncogene to tumor suppressor: the dual role of Myc in leukemia. |
| Q26853567 | Functional interactions among members of the MAX and MLX transcriptional network during oncogenesis |
| Q35885872 | Functions of myc:max in the control of cell proliferation and tumorigenesis |
| Q34368858 | G1 cell-cycle control and cancer |
| Q41829509 | Gamma interferon-inducible protein 10 induces HeLa cell apoptosis through a p53-dependent pathway initiated by suppression of human papillomavirus type 18 E6 and E7 expression. |
| Q39207120 | Gene delivery of cyclin-dependent kinase inhibitors p21Waf1 and p27Kip1 suppresses proliferation of MCF-7 breast cancer cells in vitro |
| Q40293911 | Generation of precursor, immature, and mature murine B1-cell lines from c-myc/bcl-xL-overexpressing pre-BI cells |
| Q95840660 | Genome-Wide Screen of the Hippocampus in Aged Rats Identifies Mitochondria, Metabolism and Aging Processes Implicated in Sevoflurane Anesthesia |
| Q37367194 | Genome-wide identification of post-translational modulators of transcription factor activity in human B cells. |
| Q35882709 | Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts. |
| Q35965143 | Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network |
| Q37083557 | Gfi-1 represses CDKN2B encoding p15INK4B through interaction with Miz-1. |
| Q42777559 | Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response |
| Q24675083 | Global mapping of c-Myc binding sites and target gene networks in human B cells |
| Q36216063 | Glucocorticoid receptor activation inhibits p53-induced apoptosis of MCF10Amyc cells via induction of protein kinase Cε. |
| Q37327647 | Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation |
| Q33705004 | HIF-1alpha induces cell cycle arrest by functionally counteracting Myc. |
| Q36694384 | High expression of Fatty Acid-Binding Protein 5 promotes cell growth and metastatic potential of colorectal cancer cells |
| Q35196929 | Highly specific in vivo gene delivery for p53-mediated apoptosis and genetic photodynamic therapies of tumour |
| Q36017473 | Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1 |
| Q39389047 | Histone demethylase KDM5B collaborates with TFAP2C and Myc to repress the cell cycle inhibitor p21(cip) (CDKN1A). |
| Q35216865 | Hypoxia. Cross talk between oxygen sensing and the cell cycle machinery |
| Q39715241 | ID1 enhances docetaxel cytotoxicity in prostate cancer cells through inhibition of p21. |
| Q28180608 | Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437 |
| Q91912673 | Identification of dynamic signatures associated with smoking-related squamous cell lung cancer and chronic obstructive pulmonary disease |
| Q46397627 | In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation. |
| Q35083785 | Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice |
| Q38310745 | Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex |
| Q27860937 | Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors |
| Q38335320 | Inhibition of p53-mediated transcriptional responses by mithramycin A. |
| Q35440540 | Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System. |
| Q28247124 | Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes |
| Q39609426 | Initial acidic pH is critical for mycelial cultures and functional exopolysaccharide production of an edible mushroom, Laetiporus sulphureus var. miniatus JM 27. |
| Q62839089 | Ink4c is dispensable for tumor suppression in Myc-induced B-cell lymphomagenesis |
| Q24657196 | Insertional mutagenesis reveals progression genes and checkpoints in MYC/Runx2 lymphomas |
| Q35818443 | Insights into the Molecular Pathogenesis of Activated B-Cell-like Diffuse Large B-Cell Lymphoma and Its Therapeutic Implications |
| Q28117650 | Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation |
| Q30866782 | Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer |
| Q38200606 | Intestinal stem cell injury and protection during cancer therapy |
| Q35953133 | Intrinsic tumour suppression |
| Q35185629 | Involvement of the INK4a/Arf gene locus in senescence |
| Q38283101 | JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression |
| Q45054538 | KLF2 inhibits Jurkat T leukemia cell growth via upregulation of cyclin-dependent kinase inhibitor p21WAF1/CIP1. |
| Q34478868 | KLF4, p21 and context-dependent opposing forces in cancer |
| Q33914646 | Kaempferol enhances cisplatin's effect on ovarian cancer cells through promoting apoptosis caused by down regulation of cMyc |
| Q80551110 | Kruppel-like factor 5 modulates p53-independent apoptosis through Pim1 survival kinase in cancer cells |
| Q64764683 | Loss of FBXO7 results in a Parkinson's-like dopaminergic degeneration via an RPL23-MDM2-TP53 pathway |
| Q37381179 | MEK plus PI3K/mTORC1/2 Therapeutic Efficacy Is Impacted by TP53 Mutation in Preclinical Models of Colorectal Cancer. |
| Q39444118 | MITOCHIP assessment of differential gene expression in the skeletal muscle of Ant1 knockout mice: coordinate regulation of OXPHOS, antioxidant, and apoptotic genes |
| Q64061957 | MYC Oncogene Contributions to Release of Cell Cycle Brakes |
| Q43791932 | MYC accelerates p21CIP-induced megakaryocytic differentiation involving early mitosis arrest in leukemia cells |
| Q33653686 | MYC and the control of DNA replication |
| Q37732974 | MYC in oncogenesis and as a target for cancer therapies |
| Q36326252 | MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression |
| Q59072385 | Mammalian MYC Proteins and Cancer |
| Q50067187 | Mechanisms of inactivation of the tumour suppressor gene RHOA in colorectal cancer |
| Q34039841 | Mechanisms of regulatory diversity within the p53 transcriptional network |
| Q97073636 | MicroRNA let-7b inhibits cell proliferation via upregulation of p21 in hepatocellular carcinoma |
| Q24595497 | MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival |
| Q33829462 | MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer |
| Q34571491 | MicroRNA-145: a potent tumour suppressor that regulates multiple cellular pathways |
| Q35199251 | Miz-1 activates gene expression via a novel consensus DNA binding motif |
| Q51320385 | Miz-1 and Max compete to engage c-Myc: implication for the mechanism of inhibition of c-Myc transcriptional activity by Miz-1. |
| Q24323957 | Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1 |
| Q28589789 | Miz1 is required for early embryonic development during gastrulation |
| Q53515893 | Molecular mechanisms of cellular senescence and immortalization of human cells. |
| Q36025970 | Molecular mechanisms of induced pluripotency |
| Q64240837 | Molecular predictors of brain metastasis-related microRNAs in lung adenocarcinoma |
| Q53569056 | Multi-scale modeling of cell survival and death mediated by the p53 network: a systems pharmacology framework. |
| Q39452841 | Myc and Miz-1 have coordinate genomic functions including targeting Hox genes in human embryonic stem cells. |
| Q40495521 | Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21Cip1 pathway |
| Q33888111 | Myc interacts with Max and Miz1 to repress C/EBPdelta promoter activity and gene expression |
| Q28190322 | Myc pathways provoking cell suicide and cancer |
| Q30480348 | Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1 |
| Q24557458 | Myc represses transcription through recruitment of DNA methyltransferase corepressor |
| Q24323093 | Myc sensitizes p53-deficient cancer cells to the DNA-damaging effects of the DNA methyltransferase inhibitor decitabine |
| Q91564632 | Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma |
| Q37299032 | Myc's broad reach |
| Q33925763 | Myc-induced microRNAs integrate Myc-mediated cell proliferation and cell fate |
| Q35733509 | Myc-interacting protein 1 target gene profile: a link to microtubules, extracellular signal-regulated kinase, and cell growth |
| Q27682280 | NMR structure note: solution structure of human Miz-1 zinc fingers 8 to 10 |
| Q33713849 | Nac1 interacts with the POZ-domain transcription factor, Miz1. |
| Q35057304 | New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? |
| Q33350410 | Nuclear translocation of Skp2 facilitates its destruction in response to TGFβ signaling |
| Q36418000 | Oncogenes in cell survival and cell death |
| Q33200353 | Opposite Smad and chicken ovalbumin upstream promoter transcription factor inputs in the regulation of the collagen VII gene promoter by transforming growth factor-beta |
| Q39924024 | PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production |
| Q28594973 | PML interacts with Myc, and Myc target gene expression is altered in PML-null fibroblasts |
| Q40200588 | PML4 induces differentiation by Myc destabilization |
| Q24550772 | PUMA mediates the apoptotic response to p53 in colorectal cancer cells |
| Q24631776 | PUMA, a potent killer with or without p53 |
| Q24304063 | Parafibromin inhibits cancer cell growth and causes G1 phase arrest |
| Q58776898 | Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells |
| Q39202249 | Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: functional and therapeutic implications. |
| Q40278949 | Polyamine-modulated c-Myc expression in normal intestinal epithelial cells regulates p21Cip1 transcription through a proximal promoter region |
| Q35302120 | Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage |
| Q34660639 | Polymorphism of ZBTB17 gene is associated with idiopathic dilated cardiomyopathy: a case control study in a Han Chinese population |
| Q64274647 | Polyomavirus T Antigen Induces Expression Using an LXCXE-Dependent and TP53-Independent Mechanism |
| Q34572279 | Predicting interactome network perturbations in human cancer: application to gene fusions in acute lymphoblastic leukemia |
| Q36131481 | Processing Oscillatory Signals by Incoherent Feedforward Loops |
| Q36965134 | Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation |
| Q42808748 | Proliferation of pulmonary interstitial fibroblasts is mediated by transforming growth factor-beta1-induced release of extracellular fibroblast growth factor-2 and phosphorylation of p38 MAPK and JNK. |
| Q35618448 | Promoter-binding and repression of PDGFRB by c-Myc are separable activities |
| Q33846392 | Promyelocytic leukemia zinc finger-retinoic acid receptor α (PLZF-RARα), an oncogenic transcriptional repressor of cyclin-dependent kinase inhibitor 1A (p21WAF/CDKN1A) and tumor protein p53 (TP53) genes |
| Q43136850 | Proto-oncogene FBI-1 represses transcription of p21CIP1 by inhibition of transcription activation by p53 and Sp1. |
| Q42414248 | Putting the brakes on p53-driven apoptosis |
| Q28284332 | Quantitative proteomic analysis of myc-induced apoptosis: a direct role for Myc induction of the mitochondrial chloride ion channel, mtCLIC/CLIC4 |
| Q37085000 | ROS and p53: a versatile partnership |
| Q36906255 | Rap2b, a novel p53 target, regulates p53-mediated pro-survival function |
| Q37333643 | Reflecting on 25 years with MYC. |
| Q24305051 | Regulation of TopBP1 oligomerization by Akt/PKB for cell survival |
| Q39911130 | Regulation of apoptosis by type III interferons. |
| Q36381798 | Regulation of cell proliferation by hypoxia-inducible factors |
| Q37398628 | Regulation of gene expression and cellular proliferation by histone H2A.Z. |
| Q37513688 | Regulation of stem cell populations by microRNAs |
| Q37641543 | Repair of UVB-induced DNA damage is reduced in melanoma due to low XPC and global genome repair |
| Q28246633 | Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1 |
| Q37006926 | Reprogramming somatic cells towards pluripotency by defined factors |
| Q24810768 | Responses of genes involved in cell cycle control to diverse DNA damaging chemicals in human lung adenocarcinoma A549 cells |
| Q37809549 | Role of 4-hydroxy-trans-2-nonenal in cell functions |
| Q49303056 | Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia. |
| Q36921552 | Roles of Smad3 in TGF-beta signaling during carcinogenesis |
| Q37339711 | Roles of TGFbeta in metastasis |
| Q24298821 | SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing |
| Q28584062 | SMAD3 prevents binding of NKX2.1 and FOXA1 to the SpB promoter through its MH1 and MH2 domains |
| Q34478968 | Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4. |
| Q34187808 | Senescence, apoptosis and therapy--cutting the lifelines of cancer. |
| Q34009416 | Serum-nutrient starvation induces cell death mediated by Bax and Puma that is counteracted by p21 and unmasked by Bcl-x(L) inhibition |
| Q34958801 | Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene |
| Q35478946 | Smad phosphoisoform signaling specificity: the right place at the right time |
| Q30498334 | Small RNA-mediated regulation of iPS cell generation. |
| Q35353405 | Small molecules targeting c-Myc oncogene: promising anti-cancer therapeutics |
| Q34628002 | Small-molecular modulators of cancer-associated epigenetic mechanisms |
| Q36678334 | Stabilization of p21 (Cip1/WAF1) following Tip60-dependent acetylation is required for p21-mediated DNA damage response |
| Q41904105 | Stimulus-specific transcriptional regulation within the p53 network |
| Q48222476 | Stromal gene expression defines poor-prognosis subtypes in colorectal cancer |
| Q50350048 | Structural Insights into c-Myc-interacting Zinc Finger Protein-1 (Miz-1) Delineate Domains Required for DNA Scanning and Sequence-specific Binding |
| Q45925761 | Structural and dynamical characterization of the Miz-1 zinc fingers 5-8 by solution-state NMR. |
| Q42551653 | Structures of heterodimeric POZ domains of Miz1/BCL6 and Miz1/NAC1. |
| Q36016372 | Suppression of Myc oncogenic activity by nucleostemin haploinsufficiency |
| Q85739131 | Suppression of growth and migration by blocking the Hedgehog signaling pathway in gastric cancer cells |
| Q35008939 | Switching from life to death: the Miz-ing link between Myc and p53. |
| Q37129591 | Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF beta-1 in cultured rat nucleus pulposus cells |
| Q37705428 | Systems biology and modeling in neuroblastoma: practicalities and perspectives |
| Q30488363 | TGF-beta receptor levels regulate the specificity of signaling pathway activation and biological effects of TGF-beta |
| Q39155158 | TGF-β Family Signaling in Tumor Suppression and Cancer Progression. |
| Q39029986 | TGF-β Family Signaling in the Control of Cell Proliferation and Survival |
| Q28288866 | TGFbeta in Cancer |
| Q89767723 | Target gene-independent functions of MYC oncoproteins |
| Q29617196 | Targeting MYC dependence in cancer by inhibiting BET bromodomains |
| Q27012443 | Targeting TGF-β signaling in cancer |
| Q104795035 | Targeting TGFβ signal transduction for cancer therapy |
| Q92821183 | Targeting c-MYC through Interference with NAMPT and SIRT1 and Their Association to Oncogenic Drivers in Murine Serrated Intestinal Tumorigenesis |
| Q24298658 | Targeting of Miz-1 is essential for Myc-mediated apoptosis |
| Q38474358 | Targeting ornithine decarboxylase impairs development of MYCN-amplified neuroblastoma |
| Q55314338 | Ten years of progress and promise of induced pluripotent stem cells: historical origins, characteristics, mechanisms, limitations, and potential applications. |
| Q39785267 | The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis |
| Q42701804 | The BET bromodomain inhibitor JQ1 suppresses growth of pancreatic ductal adenocarcinoma in patient-derived xenograft models. |
| Q45951863 | The CXXC finger 5 protein is required for DNA damage-induced p53 activation. |
| Q37099446 | The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity. |
| Q38870781 | The Effects of miR-20a on p21: Two Mechanisms Blocking Growth Arrest in TGF-β-Responsive Colon Carcinoma. |
| Q34182321 | The Max b-HLH-LZ can transduce into cells and inhibit c-Myc transcriptional activities |
| Q37468740 | The Smad7-Skp2 complex orchestrates Myc stability, impacting on the cytostatic effect of TGF-β |
| Q37728617 | The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy |
| Q33979793 | The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy |
| Q40241168 | The cell cycle inhibitor p21waf1 binds to the myc and cdc25A promoters upon DNA damage and induces transcriptional repression |
| Q37836006 | The connections between neural crest development and neuroblastoma |
| Q96128346 | The deubiquitinating enzyme UCHL1 promotes resistance to pemetrexed in non-small cell lung cancer by upregulating thymidylate synthase |
| Q24336460 | The euchromatic and heterochromatic landscapes are shaped by antagonizing effects of transcription on H2A.Z deposition |
| Q40764184 | The expression of survivin and its related genes in adipocyte-derived stem cell by demethylation |
| Q46772707 | The fate of irradiated tumor cells |
| Q39440454 | The human papillomavirus type 16 E7 oncoprotein targets Myc-interacting zinc-finger protein-1. |
| Q28468629 | The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer |
| Q37529522 | The molecular mechanism of induced pluripotency: a two-stage switch |
| Q34846077 | The multifunctional sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate p21-dependent cell-cycle arrest. |
| Q24557451 | The p400 E1A-associated protein is a novel component of the p53 --> p21 senescence pathway |
| Q28259725 | The p53 circuit board |
| Q48973971 | The proto-oncoprotein KR-POK represses transcriptional activation of CDKN1A by MIZ-1 through competitive binding |
| Q27010254 | The role of MIZ-1 in MYC-dependent tumorigenesis |
| Q28299585 | The role of histone deacetylase 7 (HDAC7) in cancer cell proliferation: regulation on c-Myc |
| Q35818437 | The role of intracellular calcium for the development and treatment of neuroblastoma |
| Q37964588 | The roles of TGF-β signaling in carcinogenesis and breast cancer metastasis |
| Q64377884 | The survival of antigen-stimulated T cells requires NFkappaB-mediated inhibition of p73 expression |
| Q33924983 | The transcriptional repressor dMnt is a regulator of growth in Drosophila melanogaster |
| Q43007546 | The wind rose of human keratinocyte cell fate |
| Q34068377 | Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase |
| Q35766387 | Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD. |
| Q35034543 | Threonine 32 (Thr32) of FoxO3 is critical for TGF-β-induced apoptosis via Bim in hepatocarcinoma cells |
| Q24315714 | Tip60 and p400 are both required for UV-induced apoptosis but play antagonistic roles in cell cycle progression |
| Q47377084 | Transcriptional profile of postmortem skeletal muscle |
| Q36215755 | Transcriptional regulation and transformation by Myc proteins |
| Q37777267 | Transcriptional regulation by p53. |
| Q39583166 | Transcriptional regulation of Wnt inhibitory factor-1 by Miz-1/c-Myc. |
| Q37903692 | Transcriptional repression: the dark side of myc. |
| Q37412688 | Tumor suppressive functions of p53 |
| Q31164546 | Tumor suppressor DYRK1A effects on proliferation and chemoresistance of AML cells by downregulating c-Myc |
| Q53374378 | Tumor suppressor p16INK4a determines sensitivity of human cells to transformation by cooperating cellular oncogenes |
| Q57161316 | Ubiquitination by HUWE1 in tumorigenesis and beyond |
| Q52721588 | Uhrf1 regulates germinal center B cell expansion and affinity maturation to control viral infection. |
| Q35172779 | Why did p53 gene therapy fail in ovarian cancer? |
| Q24647067 | Widespread microRNA repression by Myc contributes to tumorigenesis |
| Q24308905 | Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation |
| Q24653312 | c-Myc Augments Gamma Irradiation-Induced Apoptosis by Suppressing Bcl-XL |
| Q44450072 | c-Myc degradation induced by DNA damage results in apoptosis of CHO cells |
| Q36671497 | c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis. |
| Q42458575 | c-Myc represses the proximal promoters of GADD45a and GADD153 by a post-RNA polymerase II recruitment mechanism |
| Q51642930 | c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1. |
| Q40448475 | c-Myc suppresses p21WAF1/CIP1 expression during estrogen signaling and antiestrogen resistance in human breast cancer cells. |
| Q41878064 | cMyc-p53 feedback mechanism regulates the dynamics of T lymphocytes in the immune response |
| Q24634704 | miR-145-mediated suppression of cell growth, invasion and metastasis |
| Q90637848 | miR-197-3p Represses the Proliferation of Prostate Cancer by Regulating the VDAC1/AKT/β-catenin Signaling Axis |
| Q35157731 | microRNAs modulate iPS cell generation. |
| Q37678802 | mir-17-92: a polycistronic oncomir with pleiotropic functions |
| Q36259218 | p21 deficiency is susceptible to osteoarthritis through STAT3 phosphorylation. |
| Q54647670 | p21 does not protect cancer cells from apoptosis induced by nongenotoxic p53 activation |
| Q36088890 | p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium |
| Q42705690 | p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity |
| Q35917048 | p21 transcription is regulated by differential localization of histone H2A.Z. |
| Q40647697 | p21/CDKN1A mediates negative regulation of transcription by p53. |
| Q44400081 | p21Cip1 gene expression is modulated by Egr1: a novel regulatory mechanism involved in the resveratrol antiproliferative effect. |
| Q36638961 | p21Cip1 modulates arterial wound repair through the stromal cell-derived factor-1/CXCR4 axis in mice. |
| Q40101932 | p21WAF1/CIP1 is a common transcriptional target of retinoid receptors: pleiotropic regulatory mechanism through retinoic acid receptor (RAR)/retinoid X receptor (RXR) heterodimer and RXR/RXR homodimer |
| Q35620816 | p21Waf1/Cip1 as a therapeutic target in breast and other cancers |
| Q92422648 | p21cip1/waf1 Coordinate Autophagy, Proliferation and Apoptosis in Response to Metabolic Stress |
| Q37504409 | p27kip1 maintains a subset of leukemia stem cells in the quiescent state in murine MLL-leukemia |
| Q33905382 | p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels |
| Q28587920 | p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication |
| Q34794097 | p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop |
| Q24644779 | p53 represses c-Myc through induction of the tumor suppressor miR-145 |
| Q42362115 | p53, SKP2, and DKK3 as MYCN Target Genes and Their Potential Therapeutic Significance |
| Q39716133 | p53- and p21-dependent premature APC/C-Cdh1 activation in G2 is part of the long-term response to genotoxic stress |
| Q33925109 | p53-Dependent transcriptional repression of c-myc is required for G1 cell cycle arrest |
| Q36341584 | p53-Independent regulation of p21Waf1/Cip1 expression and senescence by PRMT6 |
| Q34397020 | p53-mediated apoptosis requires inositol hexakisphosphate kinase-2 |
| Q35774033 | p63 regulates human keratinocyte proliferation via MYC-regulated gene network and differentiation commitment through cell adhesion-related gene network |
| Q40572173 | pCLPG: a p53-driven retroviral system |
| Q81127317 | siRNA-mediated knockdown of Pdcd4 expression causes upregulation of p21(Waf1/Cip1) expression |
| Q42737506 | β-Catenin-dependent FGF signaling sustains cell survival in the anterior embryonic head by countering Smad4. |
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