| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Robert H Weiss | |
| P2860 | cites work | New functional activities for the p21 family of CDK inhibitors | Q24313427 |
| The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases | Q24319848 | ||
| Cytoplasmic p21WAF1/CIP1 expression is correlated with HER-2/ neu in breast cancer and is an independent predictor of prognosis | Q24802985 | ||
| CDK inhibitors: positive and negative regulators of G1-phase progression | Q27860983 | ||
| WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
| p21 is a universal inhibitor of cyclin kinases | Q28257305 | ||
| Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: ETS-1 regulates basal and and inducible p21WAF1/Cip: ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting [...] | Q28574779 | ||
| Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control | Q29616465 | ||
| Applications of one-bead one-compound combinatorial libraries and chemical microarrays in signal transduction research | Q31146586 | ||
| Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells | Q32084034 | ||
| Disruption of p53 in human cancer cells alters the responses to therapeutic agents | Q33853609 | ||
| Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation | Q33890494 | ||
| Loss of the cell cycle inhibitors p21(Cip1) and p27(Kip1) enhances tumorigenesis in knockout mouse models | Q34162785 | ||
| Papillomavirus E2 induces senescence in HPV-positive cells via pRB- and p21(CIP)-dependent pathways | Q34676199 | ||
| p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential | Q35595760 | ||
| Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence | Q35805158 | ||
| Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways | Q35815917 | ||
| Triptolide and chemotherapy cooperate in tumor cell apoptosis. A role for the p53 pathway | Q38307231 | ||
| Functional analysis of a p21WAF1,CIP1,SDI1 mutant (Arg94 --> Trp) identified in a human breast carcinoma. Evidence that the mutation impairs the ability of p21 to inhibit cyclin-dependent kinases. | Q38356227 | ||
| Development and effects of immunoliposomes carrying an antisense oligonucleotide against DHFR RNA and directed toward human breast cancer cells overexpressing HER2. | Q38359884 | ||
| Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells | Q39460733 | ||
| Evidence of gene deletion of p21 (WAF1/CIP1), a cyclin-dependent protein kinase inhibitor, in thyroid carcinomas | Q39999953 | ||
| Complete inhibition of Cdk/cyclin by one molecule of p21(Cip1) | Q40446483 | ||
| Stoichiometry of cyclin A-cyclin-dependent kinase 2 inhibition by p21Cip1/Waf1. | Q40842771 | ||
| p21(Waf1/Cip1) is an assembly factor required for platelet-derived growth factor-induced vascular smooth muscle cell proliferation | Q40890075 | ||
| A non-enzymatic p21 protein inhibitor of stress-activated protein kinases | Q41190478 | ||
| p21-containing cyclin kinases exist in both active and inactive states | Q41451975 | ||
| Cytoplasmic p21(Cip1/WAF1) regulates neurite remodeling by inhibiting Rho-kinase activity | Q41877559 | ||
| The cyclin-dependent kinase inhibitor p21CIP/WAF is a positive regulator of insulin-like growth factor I-induced cell proliferation in MCF-7 human breast cancer cells | Q42444777 | ||
| Associations between common polymorphisms in TP53 and p21WAF1/Cip1 and phenotypic features of breast cancer | Q43901544 | ||
| ErbB2 overexpression in human breast carcinoma is correlated with p21Cip1 up-regulation and tyrosine-15 hyperphosphorylation of p34Cdc2: poor responsiveness to chemotherapy with cyclophoshamide methotrexate, and 5-fluorouracil is associated with Erb | Q44584669 | ||
| Cytosolic p21Waf1/Cip1 increases cell cycle transit in vascular smooth muscle cells | Q44668324 | ||
| Overcoming of radioresistance in human gliomas by p21WAF1/CIP1 antisense oligonucleotide | Q48860328 | ||
| The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression. | Q52522951 | ||
| Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21 | Q59054204 | ||
| Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage | Q59098609 | ||
| Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard | Q62746044 | ||
| Novel polymorphism in p21(waf1/cip1) cyclin dependent kinase inhibitor gene: association with human esophageal cancer | Q73404589 | ||
| Paclitaxel increases p21 synthesis and accumulation of its AKT-phosphorylated form in the cytoplasm of cancer cells | Q73425422 | ||
| Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis | Q74449037 | ||
| Interaction with cyclin-dependent kinases and PCNA modulates proteasome-dependent degradation of p21 | Q77585572 | ||
| Suppression of breast cancer growth and angiogenesis by an antisense oligodeoxynucleotide to p21(Waf1/Cip1) | Q78554990 | ||
| P433 | issue | 6 | |
| P304 | page(s) | 425-429 | |
| P577 | publication date | 2003-12-01 | |
| P1433 | published in | Cancer Cell | Q280018 |
| P1476 | title | p21Waf1/Cip1 as a therapeutic target in breast and other cancers | |
| P478 | volume | 4 |
| Q59135221 | 16-Hydroxycleroda-3,13-dien-15,16-olide induces anoikis in human renal cell carcinoma cells: involvement of focal adhesion disassembly and signaling |
| Q39981678 | A dual role of p21waf1/cip1 gene in apoptosis of HEp-2 treated with cisplatin or methotrexate. |
| Q36677729 | A novel p21 attenuator which is structurally related to sorafenib |
| Q34026139 | Acetonic extract of Buxus sempervirens induces cell cycle arrest, apoptosis and autophagy in breast cancer cells |
| Q39971336 | Activated kRas protects colon cancer cells from cucurbitacin-induced apoptosis: the role of p53 and p21. |
| Q35527116 | Activin A inhibits vascular endothelial cell growth and suppresses tumour angiogenesis in gastric cancer |
| Q35863203 | Altering cancer transcriptomes using epigenomic inhibitors |
| Q53358254 | An inhibitor of cyclin-dependent kinase, stress-induced p21Waf-1/Cip-1, mediates hepatocyte mito-inhibition during the evolution of cirrhosis. |
| Q52605706 | Analysis of Brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit. |
| Q39979342 | Antisense attenuation of p21 sensitizes kidney cancer to apoptosis in response to conventional DNA damaging chemotherapy associated with enhancement of phospho-p53. |
| Q21093282 | Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance |
| Q40288843 | Bach2 is involved in neuronal differentiation of N1E-115 neuroblastoma cells |
| Q42667002 | Bcl-2 blocks 2-methoxyestradiol induced leukemia cell apoptosis by a p27(Kip1)-dependent G1/S cell cycle arrest in conjunction with NF-kappaB activation |
| Q35657936 | Bp44mT: an orally active iron chelator of the thiosemicarbazone class with potent anti-tumour efficacy |
| Q47171862 | CDKN1A-interacting zinc finger protein 1 is a novel biomarker for lung squamous cell carcinoma |
| Q39256854 | CRM1 blockade by selective inhibitors of nuclear export attenuates kidney cancer growth |
| Q39994742 | Cancer-specific enhancement of cisplatin-induced cytotoxicity with triptolide through an interaction of inactivated glycogen synthase kinase-3beta with p53. |
| Q35426181 | Celecoxib and acetylbritannilactone interact synergistically to suppress breast cancer cell growth via COX-2-dependent and -independent mechanisms |
| Q39753134 | Cell cycle inhibitor p21/ WAF1/ CIP1 as a cofactor of MITF expression in melanoma cells |
| Q34390742 | Cell cycle regulation by the PRMT6 arginine methyltransferase through repression of cyclin-dependent kinase inhibitors |
| Q38044415 | Cell cycle regulation by the intrinsically disordered proteins p21 and p27. |
| Q35925314 | Cholera toxin induces malignant glioma cell differentiation via the PKA/CREB pathway. |
| Q42872335 | Ciclopirox enhances pancreatic islet health by modulating the unfolded protein response in diabetes |
| Q41197354 | Clinicopathological and genetic differences between low-grade and high-grade colorectal mucinous adenocarcinomas. |
| Q54282221 | Combination of acyclic retinoid with branched-chain amino acids inhibits xenograft growth of human hepatoma cells in nude mice. |
| Q28297100 | DCPIP (2,6-dichlorophenolindophenol) as a genotype-directed redox chemotherapeutic targeting NQO1*2 breast carcinoma |
| Q36557412 | Differential targeting of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by chelators with anti-proliferative activity in a range of tumor cell-types |
| Q39907457 | Disparate effects of roscovitine on renal tubular epithelial cell apoptosis and senescence: implications for autosomal dominant polycystic kidney disease |
| Q38759201 | Dual and Specific Inhibition of NAMPT and PAK4 By KPT-9274 Decreases Kidney Cancer Growth |
| Q36769047 | Fangchinoline induces G0/G1 arrest by modulating the expression of CDKN1A and CCND2 in K562 human chronic myelogenous leukemia cells |
| Q36594203 | From bead to flask: Synthesis of a complex β-amido-amide for probe-development studies |
| Q35032457 | Grape seed extract upregulates p21 (Cip1) through redox-mediated activation of ERK1/2 and posttranscriptional regulation leading to cell cycle arrest in colon carcinoma HT29 cells. |
| Q33265521 | Heterogeneity of mammary lesions represent molecular differences |
| Q39247455 | Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression |
| Q40343248 | Hodgkin's lymphoma cells express alternatively spliced forms of HDM2 with multiple effects on cell cycle control |
| Q33718622 | Homozygous deletion of the activin A receptor, type IB gene is associated with an aggressive cancer phenotype in pancreatic cancer |
| Q24294875 | Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response |
| Q40284074 | Human telomerase reverse transcriptase protects hematopoietic progenitor TF-1 cells from death and quiescence induced by cytokine withdrawal |
| Q34338550 | Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia |
| Q39119892 | Inorganic arsenic exposure induces E2F-dependent G0/G1 arrest via an increase in retinoblastoma family protein p130 in B-cell lymphoma A20 cells |
| Q38162722 | Ionizing radiation-induced responses in human cells with differing TP53 status |
| Q37177365 | Iron deprivation in cancer--potential therapeutic implications |
| Q36366495 | Kidney cancer: identification of novel targets for therapy |
| Q38214413 | Less understood issues: p21(Cip1) in mitosis and its therapeutic potential. |
| Q36853062 | Loss of p21 permits carcinogenesis from chronically damaged liver and kidney epithelial cells despite unchecked apoptosis |
| Q40288535 | MDDD, a 4,9-diazapyrenium derivative, is selectively toxic to glioma cells by inducing growth arrest at G0/G1 independently of p53. |
| Q43791932 | MYC accelerates p21CIP-induced megakaryocytic differentiation involving early mitosis arrest in leukemia cells |
| Q28385690 | Mechanisms of synergistic antileukemic interactions between valproic acid and cytarabine in pediatric acute myeloid leukemia |
| Q92083493 | Melatonin and (-)-Epigallocatechin-3-Gallate: Partners in Fighting Cancer |
| Q36170527 | Modeling resistance to pathway-targeted therapy in ovarian cancer |
| Q54696576 | Multiple microRNAs rescue from Ras-induced senescence by inhibiting p21(Waf1/Cip1). |
| Q123351319 | Network-informed discovery of multidrug combinations for ERα+/HER2-/PI3Kα-mutant breast cancer |
| Q39937602 | Nitric oxide-donating aspirin inhibits the growth of pancreatic cancer cells through redox-dependent signaling |
| Q35447625 | Overexpression p21WAF1/CIP1 in suppressing retinal pigment epithelial cells and progression of proliferative vitreoretinopathy via inhibition CDK2 and cyclin E |
| Q21245737 | Pathway analysis of kidney cancer using proteomics and metabolic profiling |
| Q42957359 | Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis |
| Q40062826 | Pivotal role of the cyclin-dependent kinase inhibitor p21WAF1/CIP1 in apoptosis and autophagy |
| Q35302120 | Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage |
| Q84241662 | Predictive factors for response to treatment in patients with advanced renal cell carcinoma |
| Q92254379 | Present and Future Prospect of Small Molecule & Related Targeted Therapy Against Human Cancer |
| Q38650689 | Prognostic Role of Cell Cycle and Proliferative Markers in Clear Cell Renal Cell Carcinoma |
| Q41045830 | PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling. |
| Q37164578 | Regulation of prostate cancer progression by galectin-3 |
| Q35948150 | Role for histone deacetylase 1 in human tumor cell proliferation |
| Q38569361 | Role of the translational repressor 4E-BP1 in the regulation of p21(Waf1/Cip1) expression by retinoids |
| Q34583585 | Salinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 protein |
| Q39542053 | Salinomycin, a p-glycoprotein inhibitor, sensitizes radiation-treated cancer cells by increasing DNA damage and inducing G2 arrest |
| Q34009416 | Serum-nutrient starvation induces cell death mediated by Bax and Puma that is counteracted by p21 and unmasked by Bcl-x(L) inhibition |
| Q39682919 | Simvastatin overcomes the resistance to serum withdrawal-induced apoptosis of lymphocytes from Alzheimer's disease patients |
| Q34756265 | Small-molecule inhibitors of p21 as novel therapeutics for chemotherapy-resistant kidney cancer |
| Q28513336 | Somatic cell type specific gene transfer reveals a tumor-promoting function for p21(Waf1/Cip1) |
| Q39431060 | Sorafenib attenuates p21 in kidney cancer cells and augments cell death in combination with DNA-damaging chemotherapy |
| Q37906461 | Stem cell microRNAs in senescence and immortalization: novel players in cancer therapy |
| Q39959245 | Synergic antitumoral effect of an IGF-IR inhibitor and trastuzumab on HER2-overexpressing breast cancer cells. |
| Q99208461 | Synergistic anticancer activity of sorafenib, paclitaxel, and radiation therapy on anaplastic thyroid cancer in vitro and in vivo |
| Q34155028 | Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles |
| Q55334340 | Synuclein gamma expression enhances radiation resistance of breast cancer cells. |
| Q28579894 | TNF-alpha-mediated apoptosis in vascular smooth muscle cells requires p73 |
| Q36326247 | Targeting cancer by binding iron: Dissecting cellular signaling pathways |
| Q36842782 | Targeting the PI3K-Akt pathway in kidney cancer |
| Q60054366 | Telomere length-dependent transcription and epigenetic modifications in promoters remote from telomere ends |
| Q36996128 | The CDK inhibitors: potential targets for therapeutic stem cell manipulations? |
| Q38710191 | The DEAD-box RNA helicase DDX41 is a novel repressor of p21WAF1/CIP1 mRNA translation |
| Q92783649 | The Multifaceted p21 (Cip1/Waf1/CDKN1A) in Cell Differentiation, Migration and Cancer Therapy |
| Q42231195 | The PPAR Gamma Agonist Troglitazone Regulates Erk 1/2 Phosphorylation via a PPARγ-Independent, MEK-Dependent Pathway in Human Prostate Cancer Cells. |
| Q90419845 | The Role of the Cyclin Dependent Kinase Inhibitor p21cip1/waf1 in Targeting Cancer: Molecular Mechanisms and Novel Therapeutics |
| Q36291117 | The activation of G protein-coupled receptor 30 (GPR30) inhibits proliferation of estrogen receptor-negative breast cancer cells in vitro and in vivo |
| Q41858880 | The differential cell signaling effects of two positional isomers of the anticancer NO-donating aspirin |
| Q36507087 | The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1 |
| Q37130026 | The experimental chemotherapeutic N6-furfuryladenosine (kinetin-riboside) induces rapid ATP depletion, genotoxic stress, and CDKN1A(p21) upregulation in human cancer cell lines |
| Q40525768 | The fate of pancreatic tumor cell lines following p16 overexpression depends on the modulation of CDK2 activity |
| Q36969635 | The inhibitory effect of ellagic Acid on cell growth of ovarian carcinoma cells |
| Q35371834 | The p73 tumor suppressor is targeted by Pirh2 RING finger E3 ubiquitin ligase for the proteasome-dependent degradation |
| Q28242137 | The role of p21 in regulating mammalian regeneration |
| Q35559007 | miR-24-2 controls H2AFX expression regardless of gene copy number alteration and induces apoptosis by targeting antiapoptotic gene BCL-2: a potential for therapeutic intervention. |
| Q61818130 | p21 Regulation by hYSK1 Activates SP-1 Transcription Factor and Increases MMP-2 Expression under Hypoxic Conditions |
| Q34291251 | p21 as a transcriptional co-repressor of S-phase and mitotic control genes |
| Q33294928 | p21 is decreased in polycystic kidney disease and leads to increased epithelial cell cycle progression: roscovitine augments p21 levels |
| Q36781240 | p21(WAF1) modulates drug-induced apoptosis and cell cycle arrest in B-cell precursor acute lymphoblastic leukemia. |
| Q34685574 | p21CIP-1/WAF-1 induction is required to inhibit prostate cancer growth elicited by deficient expression of the Wnt inhibitor Dickkopf-1 |
| Q81127317 | siRNA-mediated knockdown of Pdcd4 expression causes upregulation of p21(Waf1/Cip1) expression |
| Q35930626 | β-catenin regulates c-Myc and CDKN1A expression in breast cancer cells. |
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