| scholarly article | Q13442814 |
| P50 | author | Bert Vogelstein | Q827502 |
| Kenneth W. Kinzler | Q28031580 | ||
| P2093 | author name string | Waldman T | |
| Polyak K | |||
| He TC | |||
| P4510 | describes a project that uses | DLD-1 CDKN1A(-/-) | Q54831155 |
| HCT 116 CDKN1A(-/-) | Q54881926 | ||
| P433 | issue | 15 | |
| P921 | main subject | apoptotic process | Q14599311 |
| cell line | Q21014462 | ||
| P304 | page(s) | 1945-1952 | |
| P577 | publication date | 1996-08-01 | |
| P1433 | published in | Genes & Development | Q1524533 |
| P1476 | title | Genetic determinants of p53-induced apoptosis and growth arrest | |
| P478 | volume | 10 |
| Q28276061 | 14-3-3sigma is a p53-regulated inhibitor of G2/M progression |
| Q53467671 | 5-Aza-2'-deoxycytidine restores proapoptotic function of p53 in cancer cells resistant to p53-induced apoptosis. |
| Q28369128 | 5-Fluorouracil induces apoptosis in human colon cancer cell lines with modulation of Bcl-2 family proteins |
| Q92286168 | A Bird's-Eye View of the Multiple Biochemical Mechanisms that Propel Pathology of Alzheimer's Disease: Recent Advances and Mechanistic Perspectives on How to Halt the Disease Progression Targeting Multiple Pathways |
| Q47069275 | A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegans |
| Q24313374 | A model for p53-induced apoptosis |
| Q24306061 | A mouse model uncovers LKB1 as an UVB-induced DNA damage sensor mediating CDKN1A (p21WAF1/CIP1) degradation |
| Q40979443 | A newly developed adenovirus-mediated transfer of a wild-type p53 gene increases sensitivity to cis-diamminedichloroplatinum (II) in p53-deleted ovarian cancer cells |
| Q50627384 | A novel cytostatic process enhances the productivity of Chinese hamster ovary cells. |
| Q39836853 | A novel p53 target gene, S100A9, induces p53-dependent cellular apoptosis and mediates the p53 apoptosis pathway |
| Q42521789 | A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis. |
| Q40847256 | A serine 37 mutation associated with two missense mutations at highly conserved regions of p53 affect pro-apoptotic genes expression in a T-lymphoblastoid drug resistant cell line |
| Q40635501 | A simple stochastic model for the feedback circuit between p16INK4a and p53 mediated by p38MAPK: implications for senescence and apoptosis |
| Q45876577 | A transcriptional activation function of p53 is dispensable for and inhibitory of its apoptotic function |
| Q41098523 | AKT is indispensable for coordinating Par-4/JNK cross talk in p21 downmodulation during ER stress |
| Q34106554 | AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival |
| Q74478199 | Accumulation of tumor suppressor p53 in rat muscle after a space flight |
| Q40954121 | Activation of an MDM2-specific caspase by p53 in the absence of apoptosis |
| Q43630489 | Additive effect of adenovirus-mediated E2F-1 gene transfer and topoisomerase II inhibitors on apoptosis in human osteosarcoma cells |
| Q40910139 | Adenovirus type 5 E1A immortalizes primary rat cells expressing wild-type p53. |
| Q43747184 | Adenovirus-mediated transfer of the p53 family genes, p73 and p51/p63 induces cell cycle arrest and apoptosis in colorectal cancer cell lines: potential application to gene therapy of colorectal cancer |
| Q40701811 | After portal branch ligation in the rat, cellular proliferation is associated with selective induction of c-Ha-ras, p53, cyclin E, and Cdk2. |
| Q34025378 | Akt activation emulates Chk1 inhibition and Bcl2 overexpression and abrogates G2 cell cycle checkpoint by inhibiting BRCA1 foci |
| Q38826343 | Akt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis |
| Q37286351 | Anti cancer effects of curcumin: cycle of life and death |
| Q78192930 | Anti-apoptotic activity of p53 maps to the COOH-terminal domain and is retained in a highly oncogenic natural mutant |
| Q42546728 | Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPbeta |
| Q33890494 | Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation |
| Q44105781 | Asiatic acid, a triterpene, induces apoptosis through intracellular Ca2+ release and enhanced expression of p53 in HepG2 human hepatoma cells |
| Q24608960 | Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling |
| Q38317581 | BRCA1 signals ARF-dependent stabilization and coactivation of p53. |
| Q37112029 | Bcl-X(L) is the primary mediator of p21 protection against hyperoxia-induced cell death |
| Q45885319 | C-terminal deletion mutant p21(WAF1/CIP1) enhances E2F-1-mediated apoptosis in colon adenocarcinoma cells |
| Q28374816 | Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells |
| Q33775049 | Calcium and S100B regulation of p53-dependent cell growth arrest and apoptosis |
| Q43251364 | Cancer and aging: the molecular pathways |
| Q38392110 | Caspase-2 is required for DNA damage-induced expression of the CDK inhibitor p21(WAF1/CIP1) |
| Q74449037 | Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis |
| Q34045686 | Cell cycle and apoptosis |
| Q35299697 | Cell cycle regulation: repair and regeneration in acute renal failure |
| Q37341740 | Cell cycle regulatory protein expression profiles by adenovirus p53 infection in human papilloma virus-associated cervical cancer cells |
| Q33796376 | Cell proliferation and apoptosis |
| Q33735445 | Cellular responses to radiation and risk of breast cancer |
| Q64380873 | Changes in p21WAF1, pRb, Mdm-2, Bax and Bcl-2 expression in cervical cancer cell lines transfected with a p53 expressing adenovirus |
| Q24314294 | Characterization of human homologs of the Drosophila seven in absentia (sina) gene |
| Q48657475 | Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis |
| Q33774492 | Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest |
| Q34636547 | Chemoprevention utility of silibinin and Cdk4 pathway inhibition in Apc(-/+) mice |
| Q37418469 | Circulating monocytes in HIV-1-infected viremic subjects exhibit an antiapoptosis gene signature and virus- and host-mediated apoptosis resistance |
| Q47827995 | Cleavage of CDK inhibitor p21(Cip1/Waf1) by caspases is an early event during DNA damage-induced apoptosis. |
| Q24314554 | Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade |
| Q53556746 | Comprehensive assessment of P21 polymorphisms and lung cancer risk. |
| Q33959840 | Concerted regulation of wild-type p53 nuclear accumulation and activation by S100B and calcium-dependent protein kinase C. |
| Q35197422 | Cooperative effects of genes controlling the G(2)/M checkpoint |
| Q30489491 | CtBPs promote cell survival through the maintenance of mitotic fidelity. |
| Q35674559 | Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance. |
| Q38495887 | Cytogenetic characterization of two colon cell lines by using conventional G-banding, comparative genomic hybridization, and whole chromosome painting |
| Q35116663 | Decision making by p53: life, death and cancer |
| Q46772713 | Defect in serine 46 phosphorylation of p53 contributes to acquisition of p53 resistance in oral squamous cell carcinoma cells. |
| Q34283491 | Delivery of cell cycle genes to block astrocytoma growth |
| Q35941628 | Deregulation of the cell cycle by the Epstein-Barr virus |
| Q39592538 | Development of small-molecule PUMA inhibitors for mitigating radiation-induced cell death |
| Q35180318 | Different faces of the heme-heme oxygenase system in inflammation |
| Q42798283 | Different impact of p53 and p21 on the radiation response of mouse tissues |
| Q35788252 | Different responses of epidermal and hair follicular cells to radiation correlate with distinct patterns of p53 and p21 induction |
| Q36179533 | Differential effects of histone deacetylase inhibitors in tumor and normal cells-what is the toxicological relevance? |
| Q40052641 | Differential sensitivity of human colon cancer cell lines to the nucleoside analogs ARC and DRB. |
| Q39848157 | Dissection of the sequence-specific DNA binding and exonuclease activities reveals a superactive yet apoptotically impaired mutant p53 protein |
| Q73594080 | Diverse effects of 9-hydroxyellipticine on the chemosensitivity of human pancreatic cancer cells harboring p53 mutations |
| Q36780705 | Dynamic roles of p53-mediated metabolic activities in ROS-induced stress responses |
| Q36815342 | E2F1 death pathways as targets for cancer therapy |
| Q45266527 | E2F1 regulates p53R2 gene expression in p53-deficient cells |
| Q37369777 | Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases |
| Q82981921 | Effect of subcellular localization of P21 on proliferation and apoptosis of HepG2 cells |
| Q36584253 | Effects of p53 mutations on apoptosis in mouse intestinal and human colonic adenomas |
| Q33744636 | Embryonic renal epithelia: induction, nephrogenesis, and cell differentiation |
| Q40644797 | Endogenous p21WAF1/CIP1 status predicts the response of human tumor cells to wild-type p53 and p21WAF1/CIP1 overexpression |
| Q44466226 | Enforced expression of the tumor suppressor p53 renders human leukemia cells (U937) more sensitive to 1-[beta-D-arabinofuranosyl]cytosine (ara-C)-induced apoptosis |
| Q33774521 | Enhanced survival in vitro of human corneal endothelial cells using mouse embryonic stem cell conditioned medium |
| Q44619763 | Epstein–Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2 |
| Q48909768 | Expression of apoptosis related proteins in brains of patients with Alzheimer's disease |
| Q38928235 | FL118 induces p53-dependent senescence in colorectal cancer cells by promoting degradation of MdmX. |
| Q73088388 | Function for p300 and not CBP in the apoptotic response to DNA damage |
| Q41659051 | Functional role for the c-Abl protein tyrosine kinase in the cellular response to genotoxic stress |
| Q43725319 | G1 cell cycle arrest signaling in hepatic injury after intraperitoneal sepsis in rats |
| Q73408716 | Gene therapy for prostate cancer |
| Q34344691 | Genetic basis of pituitary adenoma invasiveness: a review |
| Q73540284 | Genetic determinants of response to chemotherapy in transgenic mouse mammary and salivary tumors |
| Q28573307 | HCaRG is a novel regulator of renal epithelial cell growth and differentiation causing G2M arrest |
| Q28477348 | High-content, high-throughput analysis of cell cycle perturbations induced by the HSP90 inhibitor XL888 |
| Q59091869 | How cells choose to die |
| Q36310068 | Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins |
| Q54765380 | Hyperoxia induces macrophage cell cycle arrest by adhesion-dependent induction of p21Cip1 and activation of the retinoblastoma protein. |
| Q28588449 | Identification of a novel mouse p53 target gene DDA3 |
| Q61809928 | Immunocytochemistry on Sputum Samples Predicts Prognosis of Lung Cancer |
| Q42002141 | Immunolocalization of Glutathione-Peroxidase (GPx1) in the Rat Adrenal Cortex: Correlation between Steroidogenesis and Lipid Peroxidation |
| Q72993105 | Implication of multiple mechanisms in apoptosis induced by the synthetic retinoid CD437 in human prostate carcinoma cells |
| Q43018257 | Importance of changes in epithelial cell turnover during Helicobacter pylori infection in gastric carcinogenesis |
| Q33846892 | Inactivation of p21 by E1A leads to the induction of apoptosis in DNA-damaged cells |
| Q40951167 | Induced p21waf expression in H1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin |
| Q73174259 | Induction of apoptosis in head-and-neck squamous carcinoma cells by gamma-irradiation and bleomycin is p53-independent |
| Q40864818 | Induction of apoptosis in p16INK4A mutant cell lines by adenovirus-mediated overexpression of p16INK4A protein |
| Q77157774 | Induction of p21 during ceramide-mediated apoptosis in human hepatocarcinoma cells |
| Q39798874 | Induction of p21WAF1/CIP1/SDI1 in kidney tubule cells affects the course of cisplatin-induced acute renal failure |
| Q60035743 | Induction of p21Waf1/Cip1 by TNFα requires NF-κB activity and antagonizes apoptosis in Ewing tumor cells |
| Q35058579 | Inhibiting the p53-MDM2 interaction: an important target for cancer therapy |
| Q39647108 | Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence |
| Q33967257 | Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence. |
| Q34283452 | Integration of the pRB and p53 cell cycle control pathways |
| Q61759654 | Interferon γ Induces the Expression of p21waf-1 and Arrests Macrophage Cell Cycle, Preventing Induction of Apoptosis |
| Q41080587 | Introduction of p53 induces cell-cycle arrest in p53-deficient human medullary-thyroid-carcinoma cells |
| Q73679598 | Involvement of p27(kip1) in ceramide-mediated apoptosis in HL-60 cells |
| Q35208651 | JNK targets p53 ubiquitination and degradation in nonstressed cells |
| Q36535351 | Killin is a p53-regulated nuclear inhibitor of DNA synthesis |
| Q36223723 | Knockdown of CREB3/Luman by shRNA in Mouse Granulosa Cells Results in Decreased Estradiol and Progesterone Synthesis and Promotes Cell Proliferation. |
| Q80551110 | Kruppel-like factor 5 modulates p53-independent apoptosis through Pim1 survival kinase in cancer cells |
| Q73263614 | Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model |
| Q40833596 | Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint |
| Q88076402 | Low-dose irradiation of mouse embryos increases Smad-p21 pathway activity and preserves pluripotency |
| Q40954596 | Mechanisms of apoptosis induced by the synthetic retinoid CD437 in human non-small cell lung carcinoma cells |
| Q35742409 | Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis |
| Q43925485 | Methotrexate-induced apoptosis in hepatocytes after partial hepatectomy |
| Q33843707 | Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1) |
| Q41670812 | Multiple myeloma: increasing evidence for a multistep transformation process |
| Q41656068 | Multiple pathways control cell growth and transformation: overlapping and independent activities of p53 and p21Cip1/WAF1/Sdi1. |
| Q40653594 | Mutant p53 can delay growth arrest and loss of CDK2 activity in senescing human fibroblasts without reducing p21WAF1 expression |
| Q24320018 | Mutations of mitotic checkpoint genes in human cancers |
| Q59098609 | Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage |
| Q39704391 | N,N'-Bis(2-chloroethyl)-N-nitrosourea (BCNU)-induced Apoptosis of Neural Progenitor Cells in the Developing Fetal Rat Brain |
| Q35856842 | Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo |
| Q28544803 | Novel roles for p53 in the genesis and targeting of tetraploid cancer cells |
| Q33469925 | Nuclear accumulation and activation of p53 in embryonic stem cells after DNA damage |
| Q39666504 | Nutlin's two roads toward apoptosis |
| Q36255453 | OCI-5/GPC3, a glypican encoded by a gene that is mutated in the Simpson-Golabi-Behmel overgrowth syndrome, induces apoptosis in a cell line-specific manner. |
| Q34552889 | Oncogenic functions of tumour suppressor p21(Waf1/Cip1/Sdi1): association with cell senescence and tumour-promoting activities of stromal fibroblasts |
| Q40788762 | Opposing regulation of choline deficiency-induced apoptosis by p53 and nuclear factor kappaB. |
| Q45887791 | Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo |
| Q43459613 | P21 gene variation and late-onset Alzheimer's disease in the Italian population |
| Q36621938 | P21-dependent g(1)arrest with downregulation of cyclin D1 and upregulation of cyclin E by the histone deacetylase inhibitor FR901228 |
| Q34024231 | P27 in cell cycle control and cancer. |
| Q34275177 | PDTC, metal chelating compound, induces G1 phase cell cycle arrest in vascular smooth muscle cells through inducing p21Cip1 expression: Involvement of p38 mitogen activated protein kinase |
| Q40508012 | PTEN gene targeting reveals a radiation-induced size checkpoint in human cancer cells |
| Q40021264 | PUMA inactivation protects against oxidative stress through p21/Bcl-XL inhibition of bax death |
| Q24550772 | PUMA mediates the apoptotic response to p53 in colorectal cancer cells |
| Q40932326 | Papillomavirus E2 induces p53-independent apoptosis in HeLa cells |
| Q42835435 | Platelet-derived Growth Factor (PDGF) Receptor-α-activated c-Jun NH2-terminal Kinase-1 Is Critical for PDGF-induced p21 Promoter Activity Independent of p53 |
| Q34698793 | Position-dependent expression of GADD45alpha in rat brain tumours |
| Q74284498 | Prolonged Jun N-terminal kinase (JNK) activation and the upregulation of p53 and p21(WAF1/CIP1) preceded apoptosis in hepatocytes after partial hepatectomy and cisplatin |
| Q33798040 | Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3 |
| Q38343171 | Proteolytic cleavage of the mdm2 oncoprotein during apoptosis |
| Q74615819 | Quercetin inhibited DNA synthesis and induced apoptosis associated with increase in c-fos mRNA level and the upregulation of p21WAF1CIP1 mRNA and protein expression during liver regeneration after partial hepatectomy |
| Q60609674 | RNA Interference in Pigs: Comparison of RNAi Test Systems and Expression Vectors |
| Q42850882 | Radiation-induced p53 and p21WAF-1/CIP1 expression in the murine intestinal epithelium: apoptosis and cell cycle arrest. |
| Q24675123 | Radiation-induced phosphorylation of Chk1 at S345 is associated with p53-dependent cell cycle arrest pathways |
| Q41732735 | Ras versus cyclin-dependent kinase inhibitors |
| Q24320206 | Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase |
| Q39424924 | Regulation of the Mdm2-p53 signaling axis in the DNA damage response and tumorigenesis |
| Q73665831 | Relationship between p21/WAF-1/CIP-1 and apoptosis in cervical cancer during radiation therapy |
| Q28114867 | Reprimo, a new candidate mediator of the p53-mediated cell cycle arrest at the G2 phase |
| Q40923554 | Retrovirus vectors designed for efficient transduction of cytotoxic or cytostatic genes |
| Q33810088 | Role of p53 family members in apoptosis |
| Q41515342 | Role of p53 in apoptosis. |
| Q37857744 | S-phase-coupled apoptosis in tumor suppression |
| Q24298821 | SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing |
| Q28594151 | SUMO-specific protease 2 in Mdm2-mediated regulation of p53 |
| Q90122655 | Selective induced apoptosis and cell cycle arrest in MCF7 and LNCap cell lines by skin mucus from round goby (Neogobius melanostomus) and common carp (Cyprinus carpio) through P53 expression |
| Q38300297 | Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein |
| Q43668971 | Specific tumor-cell killing with adenovirus vectors containing the apoptin gene |
| Q38813842 | Spy1 participates in the proliferation and apoptosis of epithelial ovarian cancer |
| Q53296362 | Srg3, a mouse homolog of BAF155, is a novel p53 target and acts as a tumor suppressor by modulating p21(WAF1/CIP1) expression. |
| Q78353663 | Study of the cytotoxic effect of a peptidic inhibitor of the p53-hdm2 interaction in tumor cells |
| Q40509371 | Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells |
| Q37177812 | Synergistic growth inhibition by combination of adenovirus mediated p53 transfer and cisplatin in ovarian cancer cell lines |
| Q34002435 | Synergistic tumor suppression by combined inhibition of telomerase and CDKN1A |
| Q36485161 | Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells |
| Q74234618 | Thalidomide in multiple myeloma |
| Q40609821 | The 31-kDa caspase-generated cleavage product of p130cas functions as a transcriptional repressor of E2A in apoptotic cells |
| Q38896065 | The Paradox of p53: What, How, and Why? |
| Q92906324 | The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells |
| Q33771774 | The cellular response to p53: the decision between life and death |
| Q33781484 | The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53. |
| Q41122012 | The molecular basis of embryonic kidney development |
| Q35676779 | The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage |
| Q37250694 | The orphan nuclear receptor SHP inhibits apoptosis during the monocytic differentiation by inducing p21WAF1. |
| Q39451034 | The p21(WAF1/CIP1) promoter is methylated in Rat-1 cells: stable restoration of p53-dependent p21(WAF1/CIP1) expression after transfection of a genomic clone containing the p21(WAF1/CIP1) gene |
| Q73191462 | The p21(cip1/waf1) cyclin-dependent kinase inhibitor enhances the cytotoxic effect of cisplatin in human ovarian carcinoma cells |
| Q41673584 | The p53 network |
| Q33738458 | The p53 pathway and apoptosis |
| Q24684140 | The p53 tumor suppressor targets a novel regulator of G protein signaling |
| Q24301611 | The p53-inducible E3 ubiquitin ligase p53RFP induces p53-dependent apoptosis |
| Q43854589 | The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells |
| Q26864097 | The quiescent cellular state is Arf/p53-dependent and associated with H2AX downregulation and genome stability |
| Q24533291 | The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression |
| Q38331206 | The role of DNA damage responses in p53 biology |
| Q32127877 | The role of p21(CIP1/WAF1) in growth of epithelial cells exposed to hyperoxia |
| Q34283469 | The role of p53 in human cancer |
| Q39857411 | The transcription-independent mitochondrial p53 program is a major contributor to nutlin-induced apoptosis in tumor cells |
| Q40539192 | The tumor suppressor p16(INK4a) gene is a regulator of apoptosis induced by ultraviolet light and cisplatin |
| Q34737062 | The tumor suppressor p53 can both stimulate and inhibit ultraviolet light-induced apoptosis |
| Q39020051 | Thymoquinone, a bioactive component of black caraway seeds, causes G1 phase cell cycle arrest and apoptosis in triple-negative breast cancer cells with mutant p53. |
| Q73851343 | To oxidize or not to oxidize? |
| Q36438161 | Transcription abnormalities potentiate apoptosis of normal human fibroblasts. |
| Q40715817 | Transcriptional regulation during p21WAF1/CIP1-induced apoptosis in human ovarian cancer cells |
| Q42950189 | Transcriptomal profiling of the cellular response to DNA damage mediated by Slug (Snai2). |
| Q28477217 | Tumor suppressor p53 functions as a negative regulator in IgE-mediated mast cell activation |
| Q33965851 | Tumor suppressor p53 is required to modulate BRCA1 expression |
| Q46512637 | Value of targeted treatment for testicular cancer: from molecular approaches to clinical possibilities |
| Q37087404 | Versatile functions of p53 protein in multicellular organisms |
| Q41515308 | Virus-induced apoptosis |
| Q36573040 | Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53. |
| Q40878189 | c-Myc antagonizes the effect of p53 on apoptosis and p21WAF1 transactivation in K562 leukemia cells |
| Q40796687 | p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents |
| Q34020123 | p21(WAF1/Cip1): more than a break to the cell cycle? |
| Q39787744 | p21(Waf1/Cip1/Sdi1) prevents apoptosis as well as stimulates growth in cells transformed or immortalized by human T-cell leukemia virus type 1-encoded tax. |
| Q35088432 | p21Cip1 protection against hyperoxia requires Bcl-XL and is uncoupled from its ability to suppress growth |
| Q58075189 | p21WAF1 Mutation Is Not a Predominant Alteration in Pediatric Bone Tumors |
| Q36641213 | p22/WAF1 expression in human colorectal carcinoma: association with p53, transcription factor AP-2 and prognosis |
| Q33905382 | p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels |
| Q43125238 | p53 Promotes cell survival due to the reversibility of its cell-cycle checkpoints |
| Q37874926 | p53 and Notch signaling in chronic lymphocytic leukemia: clues to identifying novel therapeutic strategies |
| Q53554850 | p53 and SCFFbw7 cooperatively restrain cyclin E-associated genome instability. |
| Q45889835 | p53 and brain tumors: from gene mutations to gene therapy |
| Q47688440 | p53 and p21 Expression levels predict organ preservation and survival in invasive bladder carcinoma treated with a combined-modality approach |
| Q53428375 | p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells. |
| Q40348690 | p53 apoptotic response to DNA damage dependent on bcl2 but not bax in head and neck squamous cell carcinoma lines |
| Q33972469 | p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death. |
| Q33889024 | p53 facilitates pRb cleavage in IL-3-deprived cells: novel pro-apoptotic activity of p53. |
| Q38752162 | p53 functional deficiency in human colon cancer cells promotes fibroblast-mediated angiogenesis and tumor growth. |
| Q34432427 | p53 inactivation by MDM2 and MDMX negative feedback loops in testicular germ cell tumors |
| Q43583302 | p53 regulates ceramide formation by neutral sphingomyelinase through reactive oxygen species in human glioma cells |
| Q40717571 | p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapy |
| Q33696861 | p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity |
| Q27860990 | p53, the cellular gatekeeper for growth and division |
| Q39716133 | p53- and p21-dependent premature APC/C-Cdh1 activation in G2 is part of the long-term response to genotoxic stress |
| Q40926717 | p53-dependent apoptosis or growth arrest induced by different forms of radiation in U2OS cells: p21WAF1/CIP1 repression in UV induced apoptosis |
| Q34305233 | p53-dependent apoptosis pathways. |
| Q41051393 | p53-independent WAF1 induction by ACNU in human glioblastoma cells |
| Q34786224 | p53-independent inhibition of proliferation and p21(WAF1/Cip1)-modulated induction of cell death by the antioxidants N-acetylcysteine and vitamin E. |
| Q41345451 | p53; from inductive signal to cellular effect |
| Q28587813 | p8-deficient fibroblasts grow more rapidly and are more resistant to adriamycin-induced apoptosis |
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