| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Lars-Gunnar Larsson | |
| Per Hydbring | |||
| P2860 | cites work | Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a | Q24324559 |
| The Myc/Max/Mad network and the transcriptional control of cell behavior | Q28141143 | ||
| Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter | Q28204860 | ||
| N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation | Q28207748 | ||
| Negative regulation of the mammalian UV response by Myc through association with Miz-1 | Q28212421 | ||
| p16INK4a induces an age-dependent decline in islet regenerative potential | Q28262230 | ||
| Non-transcriptional control of DNA replication by c-Myc | Q28307758 | ||
| Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization | Q29614701 | ||
| Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing | Q29615155 | ||
| Ras oncogenes: split personalities | Q29615405 | ||
| Cellular senescence: when bad things happen to good cells | Q29615561 | ||
| Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints | Q29617405 | ||
| Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication | Q29617915 | ||
| BRAFE600-associated senescence-like cell cycle arrest of human naevi | Q29619550 | ||
| p53 in health and disease | Q29619939 | ||
| p53 mutant mice that display early ageing-associated phenotypes | Q29622826 | ||
| Modulation of mammalian life span by the short isoform of p53. | Q30312095 | ||
| Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation | Q33591386 | ||
| Telomerase reverse transcriptase delays aging in cancer-resistant mice | Q34014691 | ||
| Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a). | Q34574445 | ||
| Short telomeres limit tumor progression in vivo by inducing senescence | Q34578690 | ||
| Cellular senescence in cancer and aging | Q34581486 | ||
| Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells. | Q35041364 | ||
| Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation | Q35928960 | ||
| Living with or without cyclins and cyclin-dependent kinases | Q35951291 | ||
| Intrinsic tumour suppression | Q35953133 | ||
| Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants | Q36142180 | ||
| The ins and outs of MYC regulation by posttranslational mechanisms | Q36599161 | ||
| Senescence in tumours: evidence from mice and humans | Q36903843 | ||
| Ras and phosphoinositide 3-kinase: partners in development and tumorigenesis | Q36997611 | ||
| Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity | Q37082118 | ||
| Apoptosis and cancer: the genesis of a research field | Q37529250 | ||
| The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy | Q37728617 | ||
| Cdk2 suppresses cellular senescence induced by the c-myc oncogene. | Q39763259 | ||
| Werner syndrome protein limits MYC-induced cellular senescence | Q39895677 | ||
| C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells | Q39954044 | ||
| Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC. | Q40115775 | ||
| Cyclin-dependent kinase 2 functions in normal DNA repair and is a therapeutic target in BRCA1-deficient cancers | Q40243253 | ||
| Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB. | Q41128352 | ||
| Tumour biology: senescence in premalignant tumours | Q42802962 | ||
| LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism. | Q45240148 | ||
| Oncogene-induced senescence as an initial barrier in lymphoma development | Q46634165 | ||
| c-Myc phosphorylation is required for cellular response to oxidative stress | Q46949063 | ||
| Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice | Q48823384 | ||
| p16INK4A is a robust in vivo biomarker of cellular aging in human skin. | Q53605130 | ||
| Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a | Q57277034 | ||
| Delayed ageing through damage protection by the Arf/p53 pathway | Q57562759 | ||
| Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage | Q59098609 | ||
| MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species | Q64388399 | ||
| Hematopoietic stem cell quiescence maintained by p21cip1/waf1 | Q73532192 | ||
| A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy | Q74117541 | ||
| c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability | Q74243929 | ||
| P275 | copyright license | Creative Commons Attribution 2.5 Generic | Q18810333 |
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | enzyme | Q8047 |
| peptide | Q172847 | ||
| transcription factor | Q407384 | ||
| DNA-binding protein | Q2252764 | ||
| cellular senescence | Q9075999 | ||
| nuclear protein | Q16860021 | ||
| proto-oncogene protein | Q66020913 | ||
| neoplasm protein | Q66894191 | ||
| cell cycle proteins | Q76598519 | ||
| P304 | page(s) | 244-250 | |
| P577 | publication date | 2010-04-01 | |
| P1433 | published in | Aging | Q2845875 |
| P1476 | title | Cdk2: a key regulator of the senescence control function of Myc. | |
| P478 | volume | 2 |
| Q47131959 | A new mutation-independent approach to cancer therapy: Inhibiting oncogenic RAS and MYC, by targeting mitochondrial biogenesis |
| Q37287539 | Aspirin may inhibit angiogenesis and induce autophagy by inhibiting mTOR signaling pathway in murine hepatocarcinoma and sarcoma models |
| Q28396027 | Chk2 deficiency in Myc overexpressing lymphoma cells elicits a synergistic lethal response in combination with PARP inhibition |
| Q36926148 | Common drugs and treatments for cancer and age-related diseases: revitalizing answers to NCI's provocative questions |
| Q35640301 | Cooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells |
| Q57808238 | Detours to Replication: Functions of Specialized DNA Polymerases during Oncogene-induced Replication Stress |
| Q43180207 | GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferation. |
| Q90482823 | Interplay between NRF1, E2F4 and MYC transcription factors regulating common target genes contributes to cancer development and progression |
| Q33657479 | Ionizing radiation reduces ADAM10 expression in brain microvascular endothelial cells undergoing stress-induced senescence |
| Q34083178 | MYC cofactors: molecular switches controlling diverse biological outcomes |
| Q36862768 | Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response |
| Q38568550 | Myc: the beauty and the beast |
| Q35005363 | Origins of Myc proteins--using intrinsic protein disorder to trace distant relatives |
| Q46237526 | PolyC-binding proteins enhance expression of the CDK2 cell cycle regulatory protein via alternative splicing |
| Q35094487 | Protein kinases as switches for the function of upstream stimulatory factors: implications for tissue injury and cancer |
| Q39224402 | Ribonucleotide reductase and thymidylate synthase or exogenous deoxyribonucleosides reduce DNA damage and senescence caused by C-MYC depletion |
| Q34966603 | Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging |
| Q36685694 | Stanniocalcin 2 enhances mesenchymal stem cell survival by suppressing oxidative stress |
| Q36152451 | The protein-interaction network with functional roles in tumorigenesis, neurodegeneration, and aging |
| Q36121341 | The role of components of the chromatin modification machinery in carcinogenesis of clear cell carcinoma of the ovary (Review) |
| Q37833424 | c-Myc induction of programmed cell death may contribute to carcinogenesis: a perspective inspired by several concepts of chemical carcinogenesis |
| Q39539367 | c-Myc influences olaquindox-induced apoptosis in human hepatoma G2 cells |
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