review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S1470-2045(03)01139-2 |
P698 | PubMed publication ID | 12850192 |
P2093 | author name string | Alain G Zeimet | |
Christian Marth | |||
P2860 | cites work | p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities | Q22003973 |
Identification of alternative splice products encoded by the human coxsackie-adenovirus receptor gene | Q28215782 | ||
Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5 | Q28303765 | ||
An anti-apoptotic role for the p53 family member, p73, during developmental neuron death | Q28505615 | ||
Mechanism of the combination effect of wild-type TP53 gene transfection and cisplatin treatment for ovarian cancer xenografts | Q64380477 | ||
Mutated p21(WAF1/CIP1/SDI1) lacking CDK-inhibitory activity fails to prevent apoptosis in human colorectal carcinoma cells | Q74261370 | ||
p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours | Q28513003 | ||
Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment | Q29615852 | ||
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6 | Q29622924 | ||
The effects of the adenovirus-mediated wild-type p53 delivery in human epithelial ovarian cancer cell line in vitro and in vivo | Q30307979 | ||
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma | Q31984891 | ||
Effect of p53 gene transfer and cisplatin in a peritonitis carcinomatosa model with p53-deficient ovarian cancer cells | Q33183313 | ||
An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism | Q33786008 | ||
Disruption of p53 in human cancer cells alters the responses to therapeutic agents | Q33853609 | ||
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New insights into p53 regulation and gene therapy for cancer. | Q34047246 | ||
p53: death star | Q34103258 | ||
Epigenetic downregulation of the retinoic acid receptor-beta2 gene in breast cancer. | Q34334842 | ||
Transcriptional targeting for ovarian cancer gene therapy | Q34352401 | ||
Apoptosis: a link between cancer genetics and chemotherapy | Q34520432 | ||
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p53-Dependent and -independent responses to cisplatin in mouse testicular teratocarcinoma cells | Q37385633 | ||
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Integrin alpha(v)beta1 is an adenovirus coreceptor | Q39606281 | ||
Human adenovirus serotypes 3 and 5 bind to two different cellular receptors via the fiber head domain | Q39869944 | ||
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Intraperitoneal recombinant interferon gamma in ovarian cancer patients with residual disease at second-look laparotomy | Q40672850 | ||
Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity | Q40795999 | ||
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Effect of p53 status on sensitivity to platinum complexes in a human ovarian cancer cell line. | Q40897672 | ||
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Promoter attenuation in gene therapy: interferon-gamma and tumor necrosis factor-alpha inhibit transgene expression | Q41074143 | ||
Genetic mechanisms of tumor suppression by the human p53 gene | Q41710706 | ||
Adenovirus-mediated wild-type p53 gene transfer in patients receiving chemotherapy for advanced non-small-cell lung cancer: results of a multicenter phase II study | Q43543620 | ||
Molecular mechanisms for aberrant expression of the human breast cancer specific gene 1 in breast cancer cells: control of transcription by DNA methylation and intronic sequences | Q43722447 | ||
In vivo molecular chemotherapy and noninvasive imaging with an infectivity-enhanced adenovirus | Q43993914 | ||
Determination of molecules regulating gene delivery using adenoviral vectors in ovarian carcinomas | Q44270897 | ||
Use of transcriptional regulatory elements of the MUC1 and ERBB2 genes to drive tumour-selective expression of a prodrug activating enzyme | Q45211397 | ||
Intraperitoneal gene therapy with adenoviral-mediated p53 tumor suppressor gene for ovarian cancer model in nude mouse | Q45857455 | ||
Neutralisation of adenovirus infectivity by ascitic fluid from ovarian cancer patients | Q45867352 | ||
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p53 Gene therapy for lung cancer | Q45886663 | ||
Intraperitoneal cisplatin plus intravenous cyclophosphamide versus intravenous cisplatin plus intravenous cyclophosphamide for stage III ovarian cancer. | Q50512108 | ||
Tumour p53 mutations exhibit promoter selective dominance over wild type p53. | Q53391608 | ||
Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage | Q59098609 | ||
P433 | issue | 7 | |
P921 | main subject | ovarian cancer | Q172341 |
gene therapy | Q213901 | ||
P304 | page(s) | 415-422 | |
P577 | publication date | 2003-07-01 | |
P1433 | published in | Lancet Oncology Commission | Q13747613 |
P1476 | title | Why did p53 gene therapy fail in ovarian cancer? | |
P478 | volume | 4 |
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Q30421664 | Development of nanoscale approaches for ovarian cancer therapeutics and diagnostics |
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Q36868494 | Engineering targeted viral vectors for gene therapy |
Q40223019 | Enriching suicide gene bearing tumor cells for an increased bystander effect |
Q34305438 | Epigenetic therapies as a promising strategy for overcoming chemoresistance in epithelial ovarian cancer |
Q35924210 | Expression and promotor hypermethylation of miR-34a in the various histological subtypes of ovarian cancer. |
Q75353680 | Focus on epithelial ovarian cancer |
Q90185529 | Folate-appended cyclodextrin carrier targets ovarian cancer cells expressing the proton-coupled folate transporter |
Q33658229 | Frequent downregulation of miR-34 family in human ovarian cancers |
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Q36429492 | Gene therapy vector design strategies for the treatment of cancer |
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Q35596405 | Gene transfer: Bax to the future for cancer therapy |
Q39851900 | Herpes simplex virus delivery to orthotopic rectal carcinoma results in an efficient and selective antitumor effect. |
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Q64238152 | Interaction between p53 and Ras signaling controls cisplatin resistance via HDAC4- and HIF-1α-mediated regulation of apoptosis and autophagy |
Q36387940 | Ionizing radiation enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human ovarian cancer |
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Q37942529 | Resuscitating wild-type p53 expression by disrupting ceramide glycosylation: a novel approach to target mutant p53 tumors |
Q38187890 | Revisiting p53 for cancer-specific chemo- and radiotherapy: ten years after |
Q33940195 | Sodium arsenite and hyperthermia modulate cisplatin-DNA damage responses and enhance platinum accumulation in murine metastatic ovarian cancer xenograft after hyperthermic intraperitoneal chemotherapy (HIPEC) |
Q34687279 | Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells |
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Q36158708 | Targeted therapy for epithelial ovarian cancer |
Q35795073 | Targeting the p53 signaling pathway in cancer therapy - the promises, challenges and perils |
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Q38635932 | The Prognostic 97 Chemoresponse Gene Signature in Ovarian Cancer |
Q36180358 | The effect of adenovirus expressing wild-type p53 on 5-fluorouracil chemosensitivity is related to p53 status in pancreatic cancer cell lines |
Q37325095 | The mitochondrial p53 pathway |
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