| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M605569200 |
| P698 | PubMed publication ID | 16956884 |
| P2093 | author name string | James H Doroshow | |
| Edward A Sausville | |||
| Indranil Mukhopadhyay | |||
| Krishnendu K Roy | |||
| P2860 | cites work | Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication | Q24290438 |
| Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase | Q24295278 | ||
| Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals | Q24314293 | ||
| Human cyclin E, a nuclear protein essential for the G1-to-S phase transition | Q24652527 | ||
| Cyclin-dependent kinase control of centrosome duplication | Q24673544 | ||
| Met receptor tyrosine kinase: enhanced signaling through adapter proteins | Q28140219 | ||
| Multidrug resistance in cancer: role of ATP-dependent transporters | Q28208049 | ||
| Met, metastasis, motility and more | Q28235183 | ||
| Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis | Q28295920 | ||
| Interaction of nucleolar protein B23 with peptides related to nuclear localization signals | Q28304070 | ||
| Principles of CDK regulation | Q29547820 | ||
| Major nucleolar proteins shuttle between nucleus and cytoplasm | Q29620425 | ||
| New roles for Src kinases in control of cell survival and angiogenesis | Q33838903 | ||
| pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v- | Q33854336 | ||
| Cellular senescence: mitotic clock or culture shock? | Q34019131 | ||
| The role of nucleophosmin in centrosome duplication | Q34526870 | ||
| Scatter-factor and semaphorin receptors: cell signalling for invasive growth | Q34632043 | ||
| Activation of tyrosine kinases in cancer | Q35600956 | ||
| Hepatocyte growth factor secreted by prostate-derived stromal cells stimulates growth of androgen-independent human prostatic carcinoma cells | Q35829375 | ||
| The tyrphostin adaphostin interacts synergistically with proteasome inhibitors to induce apoptosis in human leukemia cells through a reactive oxygen species (ROS)-dependent mechanism | Q35848514 | ||
| Drugging cell cycle kinases in cancer therapy | Q36109007 | ||
| Cancer therapy: can the challenge be MET? | Q36159458 | ||
| Novel therapeutic approaches targeting vascular endothelial growth factor and its receptors in haematological malignancies | Q36352125 | ||
| Epidermal growth factor receptor inhibition for the treatment of glioblastoma multiforme and other malignant brain tumours | Q36400537 | ||
| Protein-tyrosine phosphatases and cancer | Q36430193 | ||
| Establishment and characterisation of a human carcinoma cell line with acquired resistance to Aplidin | Q38801730 | ||
| Adaphostin and bortezomib induce oxidative injury and apoptosis in imatinib mesylate-resistant hematopoietic cells expressing mutant forms of Bcr/Abl | Q40315880 | ||
| Molecular mechanism of cell cycle blockage of hepatoma SK-Hep-1 cells by Epimedin C through suppression of mitogen-activated protein kinase activation and increased expression of CDK inhibitors p21(Cip1) and p27(Kip1). | Q40383058 | ||
| Geldanamycin derivative inhibition of HGF/SF-mediated Met tyrosine kinase receptor-dependent urokinase-plasminogen activation | Q40404956 | ||
| In vitro combination treatment with perifosine and UCN-01 demonstrates synergism against prostate (PC-3) and lung (A549) epithelial adenocarcinoma cell lines | Q40527964 | ||
| Activated c-Met signals through PI3K with dramatic effects on cytoskeletal functions in small cell lung cancer. | Q40667298 | ||
| Involvement of cell-cell interactions in the rapid stimulation of Cas tyrosine phosphorylation and Src kinase activity by transforming growth factor-beta 1. | Q40725068 | ||
| Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells | Q40796947 | ||
| The role of the transcription factor Sp1 in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells | Q41239623 | ||
| Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter | Q41267630 | ||
| Molecular cloning and characterization of the human p27Kip1 gene promoter | Q42442293 | ||
| Different early effets of tyrphostin AG957 and geldanamycins on mitogen-activated protein kinase and p120cbl phosphorylation in anti CD-3-stimulated T-lymphoblasts | Q42466688 | ||
| The effect of tyrphostin AG-556 on intimal thickening in a mouse model of arterial injury | Q42478982 | ||
| PKC, p42/44 MAPK and p38 MAPK regulate hepatocyte growth factor secretion from human astrocytoma cells. | Q42525071 | ||
| The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation | Q44023068 | ||
| In vitro and in vivo evaluations of the tyrosine kinase inhibitor NSC 680410 against human leukemia and glioblastoma cell lines | Q44228939 | ||
| Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells | Q44550478 | ||
| Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1/MEK/ERK- and AKT-dependent process | Q44675180 | ||
| Adaphostin-induced apoptosis in CLL B cells is associated with induction of oxidative stress and exhibits synergy with fludarabine | Q45075473 | ||
| Synthesis, structure-activity relationship, and p210(bcr-abl) protein tyrosine kinase activity of novel AG 957 analogs | Q45255842 | ||
| Transcriptional profiling identifies altered intracellular labile iron homeostasis as a contributing factor to the toxicity of adaphostin: decreased vascular endothelial growth factor secretion is independent of hypoxia-inducible factor-1 regulation | Q46689475 | ||
| JTT-705 blocks cell proliferation and angiogenesis through p38 kinase/p27(kip1) and Ras/p21(waf1) pathways | Q46700745 | ||
| Low-level expression of proapoptotic Bcl-2-interacting mediator in leukemic cells in patients with chronic myeloid leukemia: role of BCR/ABL, characterization of underlying signaling pathways, and reexpression by novel pharmacologic compounds. | Q46757499 | ||
| P433 | issue | 49 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 37330-37344 | |
| P577 | publication date | 2006-09-06 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Molecular mechanism of adaphostin-mediated G1 arrest in prostate cancer (PC-3) cells: signaling events mediated by hepatocyte growth factor receptor, c-Met, and p38 MAPK pathways | |
| P478 | volume | 281 |
| Q24652101 | 3,3'-Diindolylmethane induces a G(1) arrest in human prostate cancer cells irrespective of androgen receptor and p53 status |
| Q34019923 | Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1. |
| Q35597031 | Bitter melon extract impairs prostate cancer cell-cycle progression and delays prostatic intraepithelial neoplasia in TRAMP model |
| Q35248527 | Cyproheptadine, an antihistaminic drug, inhibits proliferation of hepatocellular carcinoma cells by blocking cell cycle progression through the activation of P38 MAP kinase |
| Q33741142 | Oxidative stress by targeted agents promotes cytotoxicity in hematologic malignancies |
| Q38385755 | The expression of microRNA-34a is inversely correlated with c-MET and CDK6 and has a prognostic significance in lung adenocarcinoma patients |
| Q47261122 | The inhibitory effects of capillarisin on cell proliferation and invasion of prostate carcinoma cells. |
| Q34329204 | The lipophilic bullet hits the targets: medicinal chemistry of adamantane derivatives |
| Q53253829 | Tolfenamic acid inhibits ovarian cancer cell growth and decreases the expression of c-Met and survivin through suppressing specificity protein transcription factors. |
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