Involvement of Sp1 in the transcriptional regulation of the rat insulin-like growth factor-1 gene

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Involvement of Sp1 in the transcriptional regulation of the rat insulin-like growth factor-1 gene is …
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scholarly articleQ13442814

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P356DOI10.1016/S0303-7207(00)00207-0
P698PubMed publication ID11026572

P2093author name stringJ L Zhu
L S Phillips
X P Meng
C I Pao
E N Kaytor
P2860cites workSp3 is a transcriptional activator of the human alpha2(I) collagen geneQ24308687
Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2FQ24317554
cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2Q24324880
Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expressionQ24337872
A tale of three fingers: the family of mammalian Sp/XKLF transcription factorsQ24548846
Different members of the Sp1 multigene family exert opposite transcriptional regulation of the long terminal repeat of HIV-1Q24562924
A Novel, Erythroid Cell-Specific Murine Transcription Factor that Binds to the CACCC Element and is Related to the Krüppel Family of Nuclear Proteins†Q24605651
Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genesQ24629049
Isolation of a gene encoding a functional zinc finger protein homologous to erythroid Krüppel-like factor: identification of a new multigene familyQ24651101
The retinoblastoma protein and cell cycle controlQ27860722
COUP-TF and Sp1 Interact and Cooperate in the Transcriptional Activation of the Human Immunodeficiency Virus Type 1 Long Terminal Repeat in Human Microglial CellsQ28255786
Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sitesQ28278266
Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domainQ28295806
The human POLD1 gene. Identification of an upstream activator sequence, activation by Sp1 and Sp3, and cell cycle regulationQ28303495
Transcriptional activation domain of human BTEB2, a GC box-binding factorQ28306969
Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo- and a Cys-His domainQ28564170
NF-kappa B: ten years afterQ29618566
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motifQ29620290
Regulation of Start Site Usage in the Leader Exons of the Rat Insulin-Like Growth Factor-I Gene by Development, Fasting, and DiabetesQ30834006
Characterization of a rat insulin-like growth factor I gene promoterQ33196791
A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation.Q34059393
Differential expression of alternative 5' untranslated regions in mRNAs encoding rat insulin-like growth factor I.Q34377495
Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppressionQ34396889
Cooperation between core promoter elements influences transcriptional activity in vivoQ34555034
A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activationQ34920038
Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in miceQ36392687
Transcriptional regulation of liver-specific gene expressionQ36550574
Sp1 binding plays a critical role in Erb-B2- and v-ras-mediated downregulation of alpha2-integrin expression in human mammary epithelial cellsQ36563516
Developmental expression of Sp1 in the mouseQ36688944
Transcription initiation in the two leader exons of the rat IGF-I gene occurs from disperse versus localized sitesQ70146015
Hormone ontogeny in the ovine fetus. XVI. Plasma immunoreactive somatomedin C/insulin-like growth factor I in the fetal and neonatal lamb and in the pregnant eweQ70290141
Transcriptional regulation of the rat insulin-like growth factor-I gene involves metabolism-dependent binding of nuclear proteins to a downstream regionQ71743383
Sp1 Is Phosphorylated and Its DNA Binding Activity Down-regulated upon Terminal Differentiation of the LiverQ71823770
Transcription initiation of the rat insulin-like growth factor-I gene in hepatocyte primary cultureQ71870847
Identification of novel promoter and repressor elements in the 5'-flanking regions of the rat insulin-like growth factor-I geneQ72401990
Synthesis and Secretion of Insulin-Like Growth Factor and Its Binding Protein by the Perfused Rat Liver: Dependence on Growth Hormone Status*Q72701022
Glycogenolytic and antiglycogenolytic prostaglandin E2 actions in rat hepatocytes are mediated via different signalling pathwaysQ72709220
CCAAT/enhancer-binding protein delta is a critical regulator of insulin-like growth factor-I gene transcription in osteoblastsQ77206610
Sp1 mediates glucose activation of the acetyl-CoA carboxylase promoterQ36792679
Sp1 is a critical regulator of the Wilms' tumor-1 geneQ36843618
Structure, Evolution, Expression and Regulation of Insulin-Like Growth Factors I and IIQ36922028
The major promoter of the rat insulin-like growth factor-I gene binds a protein complex that is required for basal expressionQ38290055
Stimulation of Human Insulin Receptor Gene Expression by Retinoblastoma Gene ProductQ38292018
Characterization of diverse functional elements in the upstream Sp1 domain of the rat luteinizing hormone receptor gene promoterQ38297312
The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulatorQ38306731
A transcriptional hierarchy involved in mammalian cell-type specificationQ38330572
CCAAT/enhancer-binding protein delta activates insulin-like growth factor-I gene transcription in osteoblasts. Identification of a novel cyclic AMP signaling pathway in boneQ38340134
Target Detection Assay (TDA): a versatile procedure to determine DNA binding sites as demonstrated on SP1 proteinQ38340482
Characterization of the rat insulin-like growth factor I gene promoters and identification of a minimal exon 2 promoterQ38347482
"Megaprimer" method of PCR-based mutagenesis: the concentration of megaprimer is a critical factor.Q38348177
The lung enriched transcription factor TTF-1 and the ubiquitously expressed proteins Sp1 and Sp3 interact with elements located in the minimal promoter of the rat Clara cell secretory protein geneQ38357149
In vitro transcription of the rat insulin-like growth factor-I geneQ38359149
Sp3 represses transcription when tethered to promoter DNA or targeted to promoter proximal RNA.Q38359173
The promoter activity of long terminal repeats of the HERV-H family of human retrovirus-like elements is critically dependent on Sp1 family proteins interacting with a GC/GT box located immediately 3' to the TATA boxQ39873018
Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF.Q40016157
An Sp1 binding site and the minimal promoter contribute to overexpression of the cytokeratin 18 gene in tumorigenic clones relative to that in nontumorigenic clones of a human carcinoma cell lineQ40016186
Sp1-mediated transcriptional activation is repressed by Sp3Q40792899
Sp3 Mediates Transcriptional Activation of the Leukocyte Integrin Genes CD11C and CD11B and Cooperates with c-Jun to Activate CD11CQ41091025
Sp1 activates and inhibits transcription from separate elements in the proximal promoter of the human adenine nucleotide translocase 2 (ANT2) gene.Q41176384
Transcriptional regulation of the SIS/PDGF-B gene in human osteosarcoma cells by the Sp family of transcription factorsQ41198171
Hepatocyte nuclear factor 1 alpha activates promoter 1 of the human insulin-like growth factor I gene via two distinct binding sitesQ41275485
A personal history of the origin of the somatomedin hypothesis and recent challenges to its validityQ41292058
cAMP response element-binding protein (CREB) interacts with transcription factors IIB and IID.Q41324037
Members of the Sp transcription factor family control transcription from the uteroglobin promoterQ41343650
The promoter of the salmon insulin-like growth factor I gene is activated by hepatocyte nuclear factor 1.Q41379559
The transcription factor Sp1 is required for induction of the murine GM-CSF promoter in T cellsQ41407643
Functional analysis of the rat insulin-like growth factor I gene and identification of an IGF-I gene promoterQ41625365
Structure and function of a human insulin-like growth factor-I gene promoterQ41654514
Regulation of insulin-like growth factor I receptor gene expression by Sp1: physical and functional interactions of Sp1 at GC boxes and at a CT elementQ42474843
Two Sp1-binding Sites Mediate cAMP-induced Transcription of the Bovine CYP11A Gene through the Protein Kinase A Signaling PathwayQ42479692
A Role for Sp and Helix-Loop-Helix Transcription Factors in the Regulation of the Human Id4 Gene Promoter ActivityQ42831021
Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitroQ48375884
Expression of insulin-like growth factor-I during chicken developmentQ48783326
The hepatocyte nuclear factor 3beta stimulates the transcription of the human insulin-like growth factor I gene in a direct and indirect mannerQ52198105
Serum levels of immunoreactive somatomedin A in the rat: some developmental aspectsQ52297671
Sp1 interacts with the consensus sequence for Egr-1 gene product with a cellular factor(s) and activates the transcription through this elementQ52545013
Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3.Q52550590
Insulin-like growth factor-I regulates transcription of the elastin gene through a putative retinoblastoma control element. A role for Sp3 acting as a repressor of elastin gene transcriptionQ52551371
Sp3 is a bifunctional transcription regulator with modular independent activation and repression domainsQ52552243
Role of the stimulatory proteins Sp1 and Sp3 in the regulation of transcription of the rat pyruvate kinase M geneQ52552940
Modulation of Transcription Factor Sp1 by cAMP-dependent Protein KinaseQ52553797
Sp1 and Sp3 Regulate Expression of the Neuronal Nicotinic Acetylcholine Receptor β4 Subunit GeneQ52559253
M-CAT, CArG, and Sp1 Elements Are Required for -Adrenergic Induction of the Skeletal -Actin Promoter during Cardiac Myocyte HypertrophyQ56591862
Rapid activation of rat insulin-like growth factor-I gene transcription by growth hormone reveals no alterations in deoxyribonucleic acid- protein interactions within the major promoterQ59393090
Promoter-specific activation of RNA polymerase II transcription by Sp1Q60017602
Purification and biochemical characterization of the promoter-specific transcription factor, Sp1Q61942294
Distribution and regulation of rat insulin-like growth factor I messenger ribonucleic acids encoding alternative carboxyterminal E-peptides: evidence for differential processing and regulation in liverQ68511364
P433issue1-2
P921main subjectpreproinsulinQ7240673
P304page(s)205-218
P577publication date2000-06-01
P1433published inMolecular and Cellular EndocrinologyQ1573600
P1476titleInvolvement of Sp1 in the transcriptional regulation of the rat insulin-like growth factor-1 gene
P478volume164

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cites work (P2860)
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Q28574698Insulin-responsive nuclear proteins facilitate Sp1 interactions with the insulin-like growth factor-I gene
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Q44963948Transcriptional regulation of IGF-I expression in skeletal muscle

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