Sp3 Mediates Transcriptional Activation of the Leukocyte Integrin Genes CD11C and CD11B and Cooperates with c-Jun to Activate CD11C

scientific article published on September 19, 1997

Sp3 Mediates Transcriptional Activation of the Leukocyte Integrin Genes CD11C and CD11B and Cooperates with c-Jun to Activate CD11C is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.272.38.24038
P953full work available at URLhttp://www.jbc.org/article/S0021925819658898/pdf
https://api.elsevier.com/content/article/PII:S0021925819658898?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0021925819658898?httpAccept=text/xml
https://syndication.highwire.org/content/doi/10.1074/jbc.272.38.24038
P698PubMed publication ID9295357
P5875ResearchGate publication ID13926627

P2093author name stringJ. D. Noti
P2860cites workCharacterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1Q24293686
Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expressionQ24337872
Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 geneQ24338257
Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genesQ24629049
Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structureQ24648312
Functional analyses of the transcription factor Sp4 reveal properties distinct from Sp1 and Sp3Q28119159
Retinoblastoma gene product activates expression of the human TGF-β2 gene through transcription factor ATF-2Q28291493
A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cellsQ29547557
A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarizationQ29618351
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motifQ29620290
The C-terminal zinc finger of GATA-1 or GATA-2 is sufficient to induce megakaryocytic differentiation of an early myeloid cell line.Q34059190
Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppressionQ34396889
A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activationQ34920038
Sp-1 binds promoter elements regulated by the RB protein and Sp-1-mediated transcription is stimulated by RB coexpressionQ36234059
The human beta 2 integrin CD18 promoter consists of two inverted Ets cis elementsQ36650636
Involvement of the transcription factor PU.1/Spi-1 in myeloid cell-restricted expression of an interferon-inducible gene encoding the human high-affinity Fc gamma receptorQ36662265
Cell type-specific protein-DNA interactions in the human zeta-globin upstream promoter region: displacement of Sp1 by the erythroid cell-specific factor NF-E1.Q36713834
The retinoblastoma gene product regulates Sp1-mediated transcriptionQ36816438
Regulation of transforming growth factor beta 1 gene expression by the product of the retinoblastoma-susceptibility geneQ37474961
Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene productQ37622299
Nucleoside phosphorothioatesQ38151204
Myb and Ets proteins cooperate to transactivate an early myeloid geneQ38296597
The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulatorQ38306731
Sp3 represses transcription when tethered to promoter DNA or targeted to promoter proximal RNA.Q38359173
Regulation of the leukocyte integrin gene CD11c is mediated by AP1 and Ets transcription factorsQ38362189
Mac-1: a macrophage differentiation antigen identified by monoclonal antibodyQ39557974
Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF.Q40016157
Sp1 binds two sites in the CD11c promoter in vivo specifically in myeloid cells and cooperates with AP1 to activate transcriptionQ40019025
Transcriptional activation by the parvoviral nonstructural protein NS-1 is mediated via a direct interaction with Sp1Q40021693
Sp1-mediated transcriptional activation is repressed by Sp3Q40792899
Members of the Sp transcription factor family control transcription from the uteroglobin promoterQ41343650
The leukocyte integrin gene CD11c is transcriptionally regulated during monocyte differentiationQ41353454
The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptorQ41497311
Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2FQ41591490
Human p150,95 alpha-subunit: genomic organization and analysis of the 5'-flanking regionQ41637110
Negative regulation of human c-fos expression by the retinoblastoma gene productQ41724715
Interaction of human T-cell lymphotropic virus type I Tax, Ets1, and Sp1 in transactivation of the PTHrP P2 promoterQ45764767
Differential activation of the rat phenylethanolamine N-methyltransferase gene by Sp1 and Egr-1.Q46221774
Expression of Ca2+/calmodulin-dependent protein kinase types II and IV, and reduced DNA synthesis due to the Ca2+/calmodulin-dependent protein kinase inhibitor KN-62 (1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenyl piperazine) in smaQ50336497
Human proteinase-3 expression is regulated by PU.1 in conjunction with a cytidine-rich elementQ52198102
P433issue38
P407language of work or nameEnglishQ1860
P921main subjecttranscriptional activationQ71230901
P1104number of pages8
P304page(s)24038-24045
P577publication date1997-09-01
1997-09-19
P1433published inJournal of Biological ChemistryQ867727
P1476titleSp3 Mediates Transcriptional Activation of the Leukocyte Integrin Genes CD11C and CD11B and Cooperates with c-Jun to Activate CD11C
P478volume272

Reverse relations

cites work (P2860)
Q52595898A highly active homeobox gene promoter regulated by Ets and Sp1 family members in normal granulosa cells and diverse tumor cell types
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Q40808000A role for Sp1 in the transcriptional regulation of hepatic triacylglycerol hydrolase in the mouse
Q40641526Activation of CTP:phosphocholine cytidylyltransferase alpha expression during the S phase of the cell cycle is mediated by the transcription factor Sp1.
Q58562991An innovative approach to predict immune-associated genes mutually targeted by cow and human milk microRNAs expression profiles
Q38314482Bayesian variable selection for gene expression modeling with regulatory motif binding sites in neuroinflammatory events
Q42379626Butyrate suppresses expression of neuropilin I in colorectal cell lines through inhibition of Sp1 transactivation
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Q38301697Characterization of Inherited Differences in Transcription of the Human Integrin alpha 2 Gene
Q33941301Characterization of Sp1, AP-1, CBF and KRC binding sites and minisatellite DNA as functional elements of the metastasis-associated mts1/S100A4 gene intronic enhancer
Q40737247Complex regulation of human neuronal nitric-oxide synthase exon 1c gene transcription. Essential role of Sp and ZNF family members of transcription factors
Q39621236Constitutive expression of the brg1 gene requires GC-boxes near to the transcriptional start site
Q38328040Differential regulation of the human nidogen gene promoter region by a novel cell-type-specific silencer element
Q38289980Discovery and validation of information theory-based transcription factor and cofactor binding site motifs
Q34443338Downregulation of c-Jun expression by transcription factor C/EBPalpha is critical for granulocytic lineage commitment
Q40766643During U937 monocytic differentiation repression of the CD43 gene promoter is mediated by the single‐stranded DNA binding protein Purα
Q40748065Functional analysis of the promoter of human sterol 27-hydroxylase gene in HepG2 cells
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