Structural and functional characterization of the leukocyte integrin gene CD11d. Essential role of Sp1 and Sp3.

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Structural and functional characterization of the leukocyte integrin gene CD11d. Essential role of Sp1 and Sp3. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.275.12.8959
P8608Fatcat IDrelease_n65w2lcdsnhgdhgnilzq66mkri
P698PubMed publication ID10722744
P5875ResearchGate publication ID280295481

P2093author name stringJohnson AK
Noti JD
Dillon JD
P2860cites workO-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulationQ24296741
Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expressionQ24337872
Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structureQ24648312
Structure and function of leukocyte integrinsQ28249413
Mapping of the human CD11c (ITGAX) and CD11d (ITGAD) genes demonstrates that they are arranged in tandem separated by no more than 11.5 kbQ28271538
Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domainQ28295806
A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarizationQ29618351
The "initiator" as a transcription control elementQ29619589
Cloning and chromosomal localization of a novel gene-encoding a human beta 2-integrin alpha subunitQ34385063
A novel leukointegrin, alpha d beta 2, binds preferentially to ICAM-3.Q34394279
Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppressionQ34396889
A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activationQ34920038
Sp-1 binds promoter elements regulated by the RB protein and Sp-1-mediated transcription is stimulated by RB coexpressionQ36234059
The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulatorQ38306731
In vivo footprinting of rat TAT gene: Dynamic interplay between the glucocorticoid receptor and a liver-specific factorQ38332154
Transcription Factors Sp1 and Sp3 Alter Vascular Endothelial Growth Factor Receptor Expression through a Novel Recognition SequenceQ38335452
PU.1 negatively regulates the CD11c integrin gene promoter through recognition of the major transcriptional start siteQ38343758
Sp3 represses transcription when tethered to promoter DNA or targeted to promoter proximal RNA.Q38359173
Regulation of the leukocyte integrin gene CD11c is mediated by AP1 and Ets transcription factorsQ38362189
Mac-1: a macrophage differentiation antigen identified by monoclonal antibodyQ39557974
LFA-1 and other accessory molecules functioning in adhesions of T and B lymphocytesQ39592883
Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF.Q40016157
Sp1 binds two sites in the CD11c promoter in vivo specifically in myeloid cells and cooperates with AP1 to activate transcriptionQ40019025
Transcriptional activation by the parvoviral nonstructural protein NS-1 is mediated via a direct interaction with Sp1Q40021693
Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigrationQ40543299
Sp3 Mediates Transcriptional Activation of the Leukocyte Integrin Genes CD11C and CD11B and Cooperates with c-Jun to Activate CD11CQ41091025
Identification of Sp1-binding sites in the CD11c (p150,95 alpha) and CD11a (LFA-1 alpha) integrin subunit promoters and their involvement in the tissue-specific expression of CD11c.Q41264896
The leukocyte integrin gene CD11c is transcriptionally regulated during monocyte differentiationQ41353454
Human p150,95 alpha-subunit: genomic organization and analysis of the 5'-flanking regionQ41637110
Transcriptional regulation by the Sp family proteins.Q41756422
CCAAT-Enhancer-binding Proteins (C/EBP) Regulate the Tissue Specific Activity of the CD11c Integrin Gene Promoter Through Functional Interactions with Sp1 ProteinsQ42446712
Role of p150,95 in adhesion, migration, chemotaxis and phagocytosis of human monocytesQ70037913
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)8959-8969
P577publication date2000-03-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleStructural and functional characterization of the leukocyte integrin gene CD11d. Essential role of Sp1 and Sp3.
P478volume275

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cites work (P2860)
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Q37340872Intact signal peptide of CD18, the beta-subunit of beta2-integrins, renders ruminants susceptible to Mannheimia haemolytica leukotoxin
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Q34370628The leukocyte integrin gene CD11d is repressed by gut-enriched Kruppel-like factor 4 in myeloid cells
Q31814879The zinc finger transcription factor transforming growth factor beta-inducible early gene-1 confers myeloid-specific activation of the leukocyte integrin CD11d promoter
Q39940985Transcription factors Sp1 and C/EBP regulate NRAMP1 gene expression
Q34042666Transcription of the transforming growth factor beta activating integrin beta8 subunit is regulated by SP3, AP-1, and the p38 pathway
Q34560830Transcriptional mechanisms regulating myeloid-specific genes
Q36731657Transient blockage of the CD11d/CD18 integrin reduces contusion volume and macrophage infiltration after traumatic brain injury in rats
Q40014819beta(2) integrin Mac-1 is a receptor for Mannheimia haemolytica leukotoxin on bovine and ovine leukocytes
Q40740551beta1 and beta2 integrins activate different signalling pathways in monocytes
Q35539301beta2-integrins in demyelinating disease: not adhering to the paradigm

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