Sp1 and Sp3 transactivate the RET proto-oncogene promoter

scientific article

Sp1 and Sp3 transactivate the RET proto-oncogene promoter is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0378-1119(00)00302-4
P698PubMed publication ID11054558

P2093author name stringRobinson BG
Mulligan LM
Delhanty PJ
Andrew SD
P2860cites workTranscriptional regulation by the Sp family proteins.Q41756422
Synergistic activation of a human promoter in vivo by transcription factor Sp1.Q41964275
Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma.Q50586207
Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3.Q52550590
Expression of the RET proto-oncogene in normal human tissues, pheochromocytomas, and other tumors of neural crest originQ71766427
Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complexQ22008642
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
RET proto-oncogene in the development of human cancerQ33718087
Neu differentiation factor stimulates phosphorylation and activation of the Sp1 transcription factorQ33957454
Transformation of mammalian cells with genes from procaryotes and eucaryotesQ34030262
A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activationQ34920038
The primary function of a redundant Sp1 binding site in the mouse aprt gene promoter is to block epigenetic gene inactivationQ38331684
Transcription factors Sp1 and Sp3 alter vascular endothelial growth factor receptor expression through a novel recognition sequenceQ38335452
Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF.Q40016157
Functional characterization of the promoter of the X-linked ectodermal dysplasia geneQ40931318
Phenylethanolamine N-methyltransferase gene expression. Sp1 and MAZ potential for tissue-specific expressionQ40966182
A 5'-CG-3'-rich region in the promoter of the transcriptionally frequently silenced RET protooncogene lacks methylated cytidine residuesQ40990404
Investigation of the genes for RET and its ligand complex, GDNF/GFR alpha-I, in small cell lung carcinomaQ41048314
Sp3 mediates transcriptional activation of the leukocyte integrin genes CD11C and CD11B and cooperates with c-Jun to activate CD11C.Q41091025
Epidermal growth factor and okadaic acid stimulate Sp1 proteolysisQ41103802
Transcriptional regulation of neuronal nicotinic acetylcholine receptor genes. Functional interactions between Sp1 and the rat beta4 subunit gene promoterQ41144513
High Sp1/Sp3 ratios in epithelial cells during epithelial differentiation and cellular transformation correlate with the activation of the HPV-16 promoter.Q41163354
P433issue1-2
P407language of work or nameEnglishQ1860
P304page(s)283-291
P577publication date2000-10-01
P1433published inGeneQ5531065
P1476titleSp1 and Sp3 transactivate the RET proto-oncogene promoter
P478volume256

Reverse relations

cites work (P2860)
Q28269502An in vitro approach to test the possible role of candidate factors in the transcriptional regulation of the RET proto-oncogene
Q40717620Cell-line specific chromatin acetylation at the Sox10-Pax3 enhancer site modulates the RET proto-oncogene expression.
Q40376696Comparative genomic sequence analysis coupled to chromatin immunoprecipitation: a screening procedure applied to search for regulatory elements at the RET locus
Q38703728Demonstration of a potent RET transcriptional inhibitor for the treatment of medullary thyroid carcinoma based on an ellipticine derivative
Q34005475Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene
Q44159321Genome-wide association study and mouse model identify interaction between RET and EDNRB pathways in Hirschsprung disease
Q33934070HOXB5 cooperates with NKX2-1 in the transcription of human RET.
Q38363068Intron 1 is required for cell type-specific, but not injury-responsive, peripherin gene expression.
Q39012303Involvement of G-quadruplex structures in regulation of human RET gene expression by small molecules in human medullary thyroid carcinoma TT cells
Q39645251Lithium induces c-Ret expression in mouse inner medullary collecting duct cells
Q38993875Mixed-ligand mononuclear copper(II) complex: crystal structure and anticancer activity
Q33843587Molecular cloning of the human platelet-derived growth factor receptor beta (PDGFR-beta) promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-beta expression
Q33857304Multilevel support vector regression analysis to identify condition-specific regulatory networks
Q24307449Regulation of c-Ret in the developing kidney is responsive to Pax2 gene dosage
Q37056141Regulation of the Human MSH6 Gene by the Sp1 Transcription Factor and Alteration of Promoter Activity and Expression by Polymorphisms
Q89813344Ret Receptor Has Distinct Alterations and Functions in Breast Cancer
Q27667674Solution structure of all parallel G-quadruplex formed by the oncogene RET promoter sequence
Q36978525Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions
Q46232266TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease
Q37580294Targeting of RET oncogene by naphthalene diimide-mediated gene promoter G-quadruplex stabilization exerts anti-tumor activity in oncogene-addicted human medullary thyroid cancer.
Q36180128The rearranged during transfection/papillary thyroid carcinoma tyrosine kinase is an estrogen-dependent gene required for the growth of estrogen receptor positive breast cancer cells
Q42438242Transcription of PRDM1, the master regulator for plasma cell differentiation, depends on an SP1/SP3/EGR-1 GC-box.
Q38361499Transcriptional repression of the RET proto-oncogene by a mitogen activated protein kinase-dependent signalling pathway