Regulation of transforming growth factor beta 1 gene expression by the product of the retinoblastoma-susceptibility gene

scientific article published on April 1991

Regulation of transforming growth factor beta 1 gene expression by the product of the retinoblastoma-susceptibility gene is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1991PNAS...88.3052K
P356DOI10.1073/PNAS.88.8.3052
P932PMC publication ID51382
P698PubMed publication ID1901652

P2093author name stringRobbins PD
Kim SJ
Roberts AB
Sporn MB
Lee HD
Busam K
P2860cites workPoint mutational inactivation of the retinoblastoma antioncogeneQ64379243
Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene productQ69389791
Promoter sequences of the human transforming growth factor-beta 1 gene responsive to transforming growth factor-beta 1 autoinductionQ69588815
Immunodetection and quantitation of the two forms of transforming growth factor-beta (TGF-beta 1 and TGF-beta 2) secreted by cells in cultureQ69936661
Differential effects of epidermal growth factor, transforming growth factor, and insulin on DNA and protein synthesis and morphology in serum-free cultures of AKR-2B cellsQ70313381
Accurate transcription initiation on a purified mouse beta-globin DNA fragment in a cell-free systemQ71327845
Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth FactorQ72399491
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cellsQ27860607
Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferationQ33583459
Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat.Q33632161
A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein bindingQ33779824
Structural and functional characterization of the transforming growth factor beta 3 promoter. A cAMP-responsive element regulates basal and induced transcriptionQ33861860
The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt lymphomaQ34055662
Type beta transforming growth factor is the primary differentiation-inducing serum factor for normal human bronchial epithelial cellsQ35599307
Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growthQ36351780
Characterization of the promoter region of the human transforming growth factor-beta 1 geneQ36416766
Reversible inhibition of mammary gland growth by transforming growth factor-betaQ36459241
Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complexQ36755274
Type beta transforming growth factor is an inhibitor of myogenic differentiationQ37405564
Type beta transforming growth factor: a bifunctional regulator of cellular growthQ37672515
Negative regulation of human c-fos expression by the retinoblastoma gene productQ41724715
Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylationQ41728185
The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T.Q41744248
Transcriptional autoregulation of the proto-oncogene fos.Q45163950
Inactivation of the retinoblastoma susceptibility gene in human breast cancersQ46241690
Oncogene jun encodes a sequence-specific trans-activator similar to AP-1.Q46795550
TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domainsQ53507560
Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.Q53521743
Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblastsQ59095246
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectretinoblastomaQ500695
P304page(s)3052-3056
P577publication date1991-04-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleRegulation of transforming growth factor beta 1 gene expression by the product of the retinoblastoma-susceptibility gene
P478volume88

Reverse relations

cites work (P2860)
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Q41116450A unique cathepsin-like protease isolated from CV-1 cells is involved in rapid degradation of retinoblastoma susceptibility gene product, RB, and transcription factor SP1.
Q40958157Abnormalities of retinoblastoma gene expression in hematological malignancies
Q36559514Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts
Q33606739Anterior diffuse retinoblastoma: mutational analysis and immunofluorescence staining
Q73423974Anti-angiogenic compound (TNP-470) inhibits mesangial cell proliferation in vitro and in vivo
Q72096814Autocrine transforming growth factor β1 blocks colony formation and progenitor cell generation by hemopoietic stem cells stimulated with steel factor
Q74107437Block-replacement mutagenesis for functional dissection of multiple transcription factor complexes
Q28362417Characterization of the MN/CA 9 promoter proximal region: a role for specificity protein (SP) and activator protein 1 (AP1) factors
Q42458805Computational identification of potential transcriptional regulators of TGF-ß1 in human atherosclerotic arteries.
Q30438817Conditional deletion of the retinoblastoma (Rb) gene in ovarian granulosa cells leads to premature ovarian failure
Q35145847Cyclin D1 expression is regulated by the retinoblastoma protein
Q73025400Detection and functional characterization of p180, a novel cell cycle regulated yeast transcription factor that binds retinoblastoma control elements
Q40641013Early gene responses to transforming growth factor-beta in cells lacking growth-suppressive RB function
Q44765106Effects of altered expression and localization of cyclophilin A on differentiation of p19 embryonic carcinoma cells
Q36808476Evidence for the involvement of protein kinase activity in transforming growth factor-beta signal transduction
Q54127845Extracellular Matrix-Associated Transforming Growth Factor-β: Role in Cancer Cell Growth and Invasion
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Q33791689Factors promoting tumor angiogenesis
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Q40017282G10BP, an E1A-inducible negative regulator of Sp1, represses transcription of the rat fibronectin gene
Q41100541How tumors become angiogenic
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Q40800435Negative regulation of transcription in eukaryotes
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Q33781230Sp1-mediated transcription of the Werner helicase gene is modulated by Rb and p53.
Q24314552Sp1/Sp3 and the myeloid zinc finger gene MZF1 regulate the human N-cadherin promoter in osteoblasts
Q41091025Sp3 Mediates Transcriptional Activation of the Leukocyte Integrin Genes CD11C and CD11B and Cooperates with c-Jun to Activate CD11C
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Q38292018Stimulation of Human Insulin Receptor Gene Expression by Retinoblastoma Gene Product
Q35870737The IE2 regulatory protein of human cytomegalovirus induces expression of the human transforming growth factor beta1 gene through an Egr-1 binding site
Q41528803The Retinoblastoma Protein: A Master Regulator of Cell Cycle, Differentiation and Apoptosis
Q40733277The cell cycle and the retinoblastoma protein family
Q44678684The expression of retinoblastoma and Sp1 is increased by low concentrations of cyclin-dependent kinase inhibitors
Q38306731The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulator
Q36816438The retinoblastoma gene product regulates Sp1-mediated transcription
Q41139639The retinoblastoma susceptibility gene RB-1 in multiple myeloma
Q38296590The retinoblastoma susceptibility gene product represses transcription when directly bound to the promoter
Q77811804The retinoblastoma susceptibility gene product/Sp1 signalling pathway is modulated by Ca2+/calmodulin kinases II and IV activity
Q52181478Tissue-specific and developmental regulation of transforming growth factor-beta1 expression in fetal lamb ductus arteriosus endothelial cells
Q71354574Transcriptional control of the cell cycle
Q72402204Transcriptional rate and steady-state changes of retinoblastoma mRNA in regenerating rat liver
Q36821079Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene
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Q41066371Transforming growth factor β1 increases the expressions of high molecular weight tropomyosin isoforms and vinculin and suppresses the transformed phenotypes in human lung carcinoma cells

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