| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/0092-8674(90)90590-B |
| P698 | PubMed publication ID | 2154332 |
| P2093 | author name string | Ludlow JW | |
| Livingston DM | |||
| Pipas JM | |||
| DeCaprio JA | |||
| Shon J | |||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | retinoblastoma | Q500695 |
| P304 | page(s) | 387-396 | |
| P577 | publication date | 1990-02-01 | |
| P1433 | published in | Cell | Q655814 |
| P1476 | title | The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T. | |
| P478 | volume | 60 |
| Q24648784 | A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock |
| Q40507980 | A novel nuclear inhibitor I-92 regulates DNA binding activity of octamer binding protein p92 during the cell cycle |
| Q33779824 | A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding |
| Q59049017 | A transcriptional tryst |
| Q40958157 | Abnormalities of retinoblastoma gene expression in hematological malignancies |
| Q41302759 | Activation of a retinoblastoma-protein-dependent pathway by sphingosine |
| Q39961031 | Activation of the tumor-specific death effector apoptin and its kinase by an N-terminal determinant of simian virus 40 large T antigen |
| Q77310904 | Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition |
| Q41118589 | Activity of the retinoblastoma family proteins, pRB, p107, and p130, during cellular proliferation and differentiation |
| Q39878446 | Adding an Rb-binding site to an N-terminally truncated simian virus 40 T antigen restores growth to high cell density, and the T common region in trans provides anchorage-independent growth and rapid growth in low serum concentrations. |
| Q40823566 | Adenovirus-E1A proteins transform cells by sequestering regulatory proteins |
| Q45985020 | Alteration in p53 modulates glial proteins in human glial tumour cells. |
| Q40926840 | Alterations of the retinoblastoma a susceptibility gene in chronic lymphocytic leukemia |
| Q41231236 | Alterations of the retinoblastoma gene in human prostate adenocarcinoma |
| Q41633870 | An SV40 transformation revertant due to a host mutation: Isolation and complementation analysis |
| Q27663961 | An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein |
| Q45408352 | Anticancer activity of an adenoviral vector expressing short hairpin RNA against BK virus T-ag. |
| Q24307564 | Association of insulin receptor substrate 1 with simian virus 40 large T antigen |
| Q35545332 | BRG1 controls the activity of the retinoblastoma protein via regulation of p21CIP1/WAF1/SDI. |
| Q40908851 | Binding of select forms of pRB to protein phosphatase type 1 independent of catalytic activity |
| Q38336379 | Biochemical characterization of phosphorylation site mutants of simian virus 40 large T antigen: evidence for interaction between amino- and carboxy-terminal domains |
| Q67941161 | Bovine cell lines for collaborative gene mapping studies |
| Q37369229 | Cell cycle control of initiation of eukaryotic DNA replication |
| Q36686032 | Cell cycle control of polyomavirus-induced transformation. |
| Q77965729 | Clinical relevance of pRb and p53 co-overexpression in soft tissue sarcomas |
| Q36684664 | Control of junB and extracellular matrix protein expression by transforming growth factor-beta 1 is independent of simian virus 40 T antigen-sensitive growth-sensitive growth-inhibitory events |
| Q41732727 | Control of pRB phosphorylation |
| Q34756189 | Cyclin A and the retinoblastoma gene product complex with a common transcription factor |
| Q24648922 | Cyclin A expression is under negative transcriptional control during the cell cycle |
| Q35849687 | Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest |
| Q40443885 | D-type cyclins |
| Q72254144 | DMSO, sodium butyrate, and TPA induce hypophosphorylation of RB with HL-60 cell differentiation |
| Q36224987 | Defective heat shock factor 1 inhibits the growth of fibrosarcoma derived from simian virus 40/T antigen‑transformed MEF cells |
| Q24304934 | Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product |
| Q38249879 | Delineating the regulation of energy homeostasis using hypothalamic cell models |
| Q35804675 | Delineation of human papillomavirus type 18 enhancer binding proteins: the intracellular distribution of a novel octamer binding protein p92 is cell cycle regulated |
| Q34630345 | Development and characterization of a mouse floxed Bmp2 osteoblast cell line that retains osteoblast genotype and phenotype |
| Q41042933 | Development of a Syngeneic Bovine Fibroblast Cell Line: Implications for the Study of Bovine Cytotoxic T Lymphocytes |
| Q40793159 | Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice |
| Q24651978 | Different roles for cyclins D1 and E in regulation of the G1-to-S transition |
| Q36634188 | Dissociation of retinoblastoma gene protein hyperphosphorylation and commitment to enter S phase |
| Q40662633 | Distinct mechanisms for regulating the tumor suppressor and antiapoptotic functions of Rb. |
| Q37627255 | Distinct sub-populations of the retinoblastoma protein show a distinct pattern of phosphorylation |
| Q36562117 | Domains A and B in the Rb pocket interact to form a transcriptional repressor motif |
| Q34436312 | Domains of E1A that bind p105Rb, p130, and p300 are required to block nerve growth factor-induced neurite growth in PC12 cells |
| Q36729356 | E1A induces phosphorylation of the retinoblastoma protein independently of direct physical association between the E1A and retinoblastoma products |
| Q41647070 | E2F transcription factor action, regulation and possible role in human cancer |
| Q35837977 | E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. |
| Q40641013 | Early gene responses to transforming growth factor-beta in cells lacking growth-suppressive RB function |
| Q73864511 | Early phosphorylation of the retinoblastoma gene product regulates protein binding to the c-fos retinoblastoma control element during T cell activation |
| Q37834897 | Epigenetic modulation of host: new insights into immune evasion by viruses |
| Q39870334 | Epstein-Barr virus nuclear antigen 3C is a transcriptional regulator |
| Q29620009 | Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties |
| Q36531361 | Expression of SV-40 T antigen in the small intestinal epithelium of transgenic mice results in proliferative changes in the crypt and reentry of villus-associated enterocytes into the cell cycle but has no apparent effect on cellular differentiation |
| Q36235611 | Expression of simian virus 40 large T (tumor) oncogene in mouse chondrocytes induces cell proliferation without loss of the differentiated phenotype |
| Q41080520 | Feedback inhibitors in normal and tumor tissues |
| Q36408019 | Functional interaction between human topoisomerase IIalpha and retinoblastoma protein |
| Q36558284 | Functional interactions between the hBRM/hBRG1 transcriptional activators and the pRB family of proteins |
| Q41744017 | G1/S regulatory mechanisms from yeast to man |
| Q35656600 | Gene expression in quiescent and senescent fibroblasts |
| Q24596103 | Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid system |
| Q45744847 | Growth-stimulating effects of tumor necrosis factor-alpha on simian virus 40-transformed human keratinocytes is linked to phosphorylation of retinoblastoma protein |
| Q36429257 | Hexamethylenebisacetamide-induced erythroleukemia cell differentiation involves modulation of events required for cell cycle progression through G1 |
| Q41127793 | High molecular weight protein phosphatase type 1 dephosphorylates the retinoblastoma protein |
| Q36293187 | How do retinoblastoma tumours form? |
| Q37371276 | How the Rb tumor suppressor structure and function was revealed by the study of Adenovirus and SV40. |
| Q33899132 | Human cytosolic and mitochondrial folylpolyglutamate synthetase are electrophoretically distinct. Expression in antifolate-sensitive and -resistant human cell lines |
| Q36775088 | Hyperphosphorylation of the retinoblastoma gene product is determined by domains outside the simian virus 40 large-T-antigen-binding regions |
| Q36702674 | Identification of a 60-kilodalton Rb-binding protein, RBP60, that allows the Rb-E2F complex to bind DNA. |
| Q29620442 | Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product |
| Q36571152 | Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen. |
| Q41670988 | Inactivation of the retinoblastoma susceptibility gene in a human high grade non-Hodgkin's lymphoma cell line |
| Q24673909 | Inducible expression of catalytically active type 1 serine/threonine protein phosphatase in a human carcinoma cell line |
| Q40396808 | Inhibition of cell proliferation by C/EBP alpha occurs in many cell types, does not require the presence of p53 or Rb, and is not affected by large T-antigen |
| Q36579279 | Interaction of retinoblastoma protein family members with large T-antigen of primate polyomaviruses |
| Q36776958 | Interferons and interleukin 6 suppress phosphorylation of the retinoblastoma protein in growth-sensitive hematopoietic cells |
| Q42793095 | Interleukin-2-dependent phosphorylation of the retinoblastoma-susceptibility-gene product p110-115RB in human T-cells |
| Q41003753 | Introduction of a normal retinoblastoma (Rb) gene into Rb-deficient lymphoblastoid cells delays tumorigenicity in immunodefective mice |
| Q42779904 | Involvement of chromatin and histone deacetylation in SV40 T antigen transcription regulation. |
| Q34278271 | Malignancy: Tumor Suppressor Gene Aberrations in Acute Myelogenous Leukemia |
| Q54102655 | Mechanism of transcriptional repression of E2F by the retinoblastoma tumor suppressor protein |
| Q29619200 | Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis |
| Q77143141 | Molecular analysis of the retinoblastoma (RB1) gene in acute myeloid leukemia patients |
| Q40917320 | Molecular and biochemical reprogramming of oncogenesis through the activity of prooxidants and antioxidants |
| Q28272090 | Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein |
| Q42807102 | Mutation of phosphoserine 389 affects p53 function in vivo |
| Q35664698 | Mutations of the retinoblastoma gene in human lymphoid neoplasms |
| Q34438346 | MyoD induced cell cycle arrest is associated with increased nuclear affinity of the Rb protein |
| Q24523723 | Negative Regulation of DNA Replication by the Retinoblastoma Protein Is Mediated by Its Association with MCM7 |
| Q37474150 | Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering |
| Q36811297 | Nuclear Binding of Purified Retinoblastoma Gene Product Is Determined by Cell Cycle-Regulated Phosphorylation |
| Q35450130 | Nuclear protein phosphorylation and growth control |
| Q73100862 | Okadaic acid suppresses TPA-induced differentiation by stimulating G1/S transition in human myeloblastic leukaemia ML-1 cells |
| Q44590170 | One allele deletion of the RB1 gene in a case of refractory anemia with del(13)(q12q14): a fluorescence in situ hybridization study of the RB1 gene |
| Q36824755 | Overproduction of Rb protein after the G1/S boundary causes G2 arrest |
| Q26991427 | PP1 and PP2A phosphatases--cooperating partners in modulating retinoblastoma protein activation |
| Q47683143 | Phosphorylation of the Retinoblastoma Protein in Childhood Acute Lymphoblastic Leukemia |
| Q36347245 | Pin1 inhibits PP2A-mediated Rb dephosphorylation in regulation of cell cycle and S-phase DNA damage |
| Q36530303 | Pocket protein function in melanocyte homeostasis and neoplasia |
| Q40048892 | Polyomavirus large and small T antigens cooperate in induction of the S phase in serum-starved 3T3 mouse fibroblasts |
| Q37102170 | Proline-directed protein phosphorylation and cell cycle regulation |
| Q36316542 | Protein kinase C signaling mediates a program of cell cycle withdrawal in the intestinal epithelium |
| Q36459445 | Protein phosphatases and DNA tumor viruses: transformation through the back door? |
| Q24323073 | Purification and characterization of human papillomavirus type 16 E7 protein with preferential binding capacity to the underphosphorylated form of retinoblastoma gene product |
| Q36668975 | RNA fingerprinting using arbitrarily primed PCR identifies differentially regulated RNAs in mink lung (Mv1Lu) cells growth arrested by transforming growth factor beta 1 |
| Q36546331 | RNA polymerase III repression by the retinoblastoma tumor suppressor protein |
| Q41386256 | RRR-alpha-tocopheryl succinate inhibits the proliferation of human prostatic tumor cells with defective cell cycle/differentiation pathways |
| Q33888705 | Rb binds c-Jun and activates transcription |
| Q41488826 | Recent insights into the functions of the retinoblastoma susceptibility gene product |
| Q34334235 | Regions and activities of simian virus 40 T antigen that cooperate with an activated ras oncogene in transforming primary rat embryo fibroblasts |
| Q40064324 | Regions of human papillomavirus type 16 E7 oncoprotein required for immortalization of human keratinocytes |
| Q36317476 | Regulation of JC virus by the POU-domain transcription factor Tst-1: implications for progressive multifocal leukoencephalopathy |
| Q41289882 | Regulation of cell cycle entry and G1 progression by CSF-1. |
| Q36050995 | Regulation of cell cycle progression and nuclear affinity of the retinoblastoma protein by protein phosphatases. |
| Q47818764 | Regulation of the Cell Cycle by the Rb Tumor Suppressor Family |
| Q37085853 | Regulation of the retinoblastoma proteins by the human herpesviruses. |
| Q40485501 | Regulation of transcription by the retinoblastoma protein |
| Q37474961 | Regulation of transforming growth factor beta 1 gene expression by the product of the retinoblastoma-susceptibility gene |
| Q40528504 | Regulatory networks of the retinoblastoma protein |
| Q36744899 | Requirement of the adenovirus E1A transformation domain 1 for inhibition of PC12 cell neuronal differentiation |
| Q34080582 | Rescue of defective mitogenic signaling by D-type cyclins. |
| Q41080352 | Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase |
| Q41065683 | Retinoblastoma gene in mouse neural development |
| Q28291493 | Retinoblastoma gene product activates expression of the human TGF-β2 gene through transcription factor ATF-2 |
| Q24563429 | Retinoblastoma gene product as a downstream target for a ceramide-dependent pathway of growth arrest |
| Q36692841 | Retinoblastoma protein and simian virus 40-dependent immortalization of human fibroblasts |
| Q41613404 | Retinoblastoma protein switches the E2F site from positive to negative element |
| Q34153888 | Retinoblastoma tumor suppressor and genome stability |
| Q35934834 | Retinoblastoma-repression of E2F-dependent transcription depends on the ability of the retinoblastoma protein to interact with E2F and is abrogated by the adenovirus E1A oncoprotein |
| Q54033603 | Reversal of an antiestrogen-mediated cell cycle arrest of MCF-7 cells by viral tumor antigens requires the retinoblastoma protein-binding domain |
| Q37380462 | Role of cyclin A and p27 in anti-IgM induced G1 growth arrest of murine B-cell lymphomas |
| Q36555544 | Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation |
| Q44138163 | SU9516, a cyclin-dependent kinase 2 inhibitor, promotes accumulation of high molecular weight E2F complexes in human colon carcinoma cells |
| Q34070113 | SV40 large T antigen functions in DNA replication and transformation |
| Q37345587 | SV40: Cell transformation and tumorigenesis |
| Q36188045 | Safety-modified episomal vectors for human gene therapy. |
| Q24308996 | Simian virus 40 large T antigen affects the Saccharomyces cerevisiae cell cycle and interacts with p34CDC28 |
| Q35859848 | Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107. |
| Q33338780 | Simian virus 40 large T antigen: the puzzle, the pieces, and the emerging picture |
| Q40794499 | Site-specific and temporally-regulated retinoblastoma protein dephosphorylation by protein phosphatase type 1. |
| Q36659274 | Specific enzymatic dephosphorylation of the retinoblastoma protein |
| Q41526922 | Strategies for Approaching Retinoblastoma Tumor Suppressor Gene Therapy |
| Q40832625 | Structural and functional contributions to the G1 blocking action of the retinoblastoma protein. (the 1992 Gordon Hamilton Fairley Memorial Lecture). |
| Q24682521 | Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor |
| Q36151923 | Structure-function analysis of the retinoblastoma tumor suppressor protein - is the whole a sum of its parts? |
| Q34314510 | Study of the role of retinoblastoma protein in terminal differentiation of murine erythroleukemia cells |
| Q36573886 | Subunit Composition Determines E2F DNA-Binding Site Specificity |
| Q41595099 | Suppression of autophagy impedes glioblastoma development and induces senescence |
| Q34273814 | Survivin is a therapeutic target in Merkel cell carcinoma. |
| Q42066126 | T antigens encoded by replication-defective simian virus 40 mutants dl1135 and 5080. |
| Q34662543 | T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesis |
| Q36564503 | The Rb family contains a conserved cyclin-dependent-kinase-regulated transcriptional repressor motif |
| Q39778001 | The SV40 T antigen modulates CBP histone acetyltransferase activity |
| Q36644993 | The adenovirus E1A-associated kinase consists of cyclin E-p33cdk2 and cyclin A-p33cdk2. |
| Q36681830 | The amino-terminal portion of CD1 of the adenovirus E1A proteins is required to induce susceptibility to tumor necrosis factor cytolysis in adenovirus-infected mouse cells |
| Q40733277 | The cell cycle and the retinoblastoma protein family |
| Q30195625 | The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions |
| Q41128953 | The evolution of small DNA viruses of eukaryotes: past and present considerations |
| Q40454392 | The molecular basis of oncogenes and tumor suppressor genes. |
| Q30577210 | The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit |
| Q41159722 | The retinoblastoma gene product (Rb) induces binding of a conformationally inactive nuclear factor-kappaB. |
| Q38306731 | The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulator |
| Q24321861 | The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest |
| Q38334818 | The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F |
| Q24564605 | The retinoblastoma protein is phosphorylated on multiple sites by human cdc2 |
| Q36962414 | The retinoblastoma protein physically associates with the human cdc2 kinase |
| Q36860853 | The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression |
| Q37537138 | The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines |
| Q36566621 | The transcription factor E2F-1 is a downstream target of RB action |
| Q35127707 | Transactivation of Human cdc2 Promoter by Adenovirus E1A |
| Q36821079 | Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene |
| Q37373014 | Transforming growth factor beta 1 (TGF beta 1) reduces cellular levels of p34cdc2, and this effect is abrogated by adenovirus independently of the E1A-associated pRB binding activity |
| Q47948675 | Tumor Suppressor Genes: Prospects for Cancer Therapies |
| Q40513956 | Tumor suppressor RASSF1A is a microtubule-binding protein that stabilizes microtubules and induces G2/M arrest |
| Q40568049 | Tumor suppressor genes and their roles in breast cancer |
| Q38020415 | Understanding the targeting of the RB family proteins by viral oncoproteins to defeat their oncogenic machinery. |
| Q36684938 | Use of transgenic mice reveals cell-specific transformation by a simian virus 40 T-antigen amino-terminal mutant |
| Q36623857 | n-Butyrate, a cell cycle blocker, inhibits the replication of polyomaviruses and papillomaviruses but not that of adenoviruses and herpesviruses. |
| Q28260456 | pRb2/p130: a new candidate for retinoblastoma tumor formation |
| Q39451919 | v-Jun overrides the mitogen dependence of S-phase entry by deregulating retinoblastoma protein phosphorylation and E2F-pocket protein interactions as a consequence of enhanced cyclin E-cdk2 catalytic activity. |
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