| scholarly article | Q13442814 |
| P2093 | author name string | W H Lee | |
| J Y Wang | |||
| B T Lin | |||
| A O Morla | |||
| S Gruenwald | |||
| P2860 | cites work | Transfer of proteins to membranes facilitates both cyanogen bromide cleavage and two-dimensional proteolytic mapping | Q46922563 |
| Human retinoblastoma susceptibility gene: cloning, identification, and sequence | Q48348004 | ||
| Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast | Q51254935 | ||
| Dephosphorylation and activation of Xenopusp34 cdc2 protein kinase during the cell cycle | Q58997203 | ||
| A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells | Q59531399 | ||
| Production of large numbers of mitotic mammalian cells by use of the reversible microtubule inhibitor Nocodazole | Q59795201 | ||
| Genetics of retinoblastoma | Q66898142 | ||
| Activation of cdc2 protein kinase during mitosis in human cells: cell cycle-dependent phosphorylation and subunit rearrangement | Q68145021 | ||
| Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+ | Q68152257 | ||
| Identification of p34 and p13, human homologs of the cell cycle regulators of fission yeast encoded by cdc2+ and suc1+ | Q68160615 | ||
| Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product | Q69389791 | ||
| The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element | Q69535058 | ||
| cdc2 is a component of the M phase-specific histone H1 kinase: evidence for identity with MPF | Q69838302 | ||
| The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity | Q24299515 | ||
| Mutation and cancer: statistical study of retinoblastoma | Q24618185 | ||
| Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2 | Q28257603 | ||
| In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase | Q28647498 | ||
| Universal control mechanism regulating onset of M-phase | Q29616481 | ||
| Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis | Q29618506 | ||
| A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma | Q29618817 | ||
| Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2 | Q29618838 | ||
| Transforming gene product of Rous sarcoma virus phosphorylates tyrosine | Q29620005 | ||
| Purification of maturation-promoting factor, an intracellular regulator of early mitotic events | Q33569974 | ||
| Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B. | Q34173355 | ||
| Expression of recessive alleles by chromosomal mechanisms in retinoblastoma | Q34264957 | ||
| Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe | Q34467598 | ||
| The retinoblastoma protein is phosphorylated during specific phases of the cell cycle | Q34507572 | ||
| Human retinoblastoma gene: long-range mapping and analysis of its deletion in a breast cancer cell line | Q36038523 | ||
| Expression and state of phosphorylation of the retinoblastoma susceptibility gene product in cycling and noncycling human hematopoietic cells. | Q37734495 | ||
| Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells | Q37734603 | ||
| cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes | Q37886477 | ||
| Structural evidence for the authenticity of the human retinoblastoma gene | Q41344591 | ||
| Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells | Q41407134 | ||
| The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T. | Q41744248 | ||
| Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis | Q42797610 | ||
| Purified maturation promoting factor phosphorylates pp60c-src at the sites phosphorylated during fibroblast mitosis | Q42798083 | ||
| Cell cycle control of DNA replication by a homologue from human cells of the p34cdc2 protein kinase | Q44272715 | ||
| Retinoblastoma and Subband Deletion of Chromosome 13 | Q45128520 | ||
| High level expression of nonfused foreign genes with Autographa californica nuclear polyhedrosis virus expression vectors | Q45846787 | ||
| Differential phosphorylation of c-Abl in cell cycle determined by cdc2 kinase and phosphatase activity. | Q46008782 | ||
| Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene. | Q46016044 | ||
| Identification of a novel proline-directed serine/threonine protein kinase in rat pheochromocytoma. | Q46078302 | ||
| Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation | Q46219366 | ||
| Antibodies detecting abnormalities of the retinoblastoma susceptibility gene product (pp110RB) in osteosarcomas and synovial sarcomas | Q46228936 | ||
| The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis | Q46234254 | ||
| A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts | Q46301168 | ||
| Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase | Q46402776 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | retinoblastoma | Q500695 |
| P304 | page(s) | 857-864 | |
| P577 | publication date | 1991-04-01 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase | |
| P478 | volume | 10 |
| Q24648784 | A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock |
| Q37641948 | A protein kinase is present in a complex with adenovirus E1A proteins |
| Q40113136 | Adenovirus E1A is associated with a serine/threonine protein kinase |
| Q33938069 | Adenovirus E1a prevents the retinoblastoma gene product from repressing the activity of a cellular transcription factor |
| Q40823566 | Adenovirus-E1A proteins transform cells by sequestering regulatory proteins |
| Q36567970 | Altered expression of the cyclin D1 and retinoblastoma genes in human esophageal cancer |
| Q40069209 | Anomalous retinoblastoma protein expression in Sternberg-Reed cells in Hodgkin's disease: a comparative study with p53 and Ki67 expression. |
| Q30584877 | Atm deletion with dual recombinase technology preferentially radiosensitizes tumor endothelium |
| Q35545332 | BRG1 controls the activity of the retinoblastoma protein via regulation of p21CIP1/WAF1/SDI. |
| Q36706168 | Biological function of the retinoblastoma protein requires distinct domains for hyperphosphorylation and transcription factor binding |
| Q34841110 | Cell cycle controls: potential targets for chemical carcinogens? |
| Q34602967 | Cell cycle molecules define a pathway required for neuron death in development and disease |
| Q39876911 | Cell cycle stage-specific phosphorylation of the Epstein-Barr virus immortalization protein EBNA-LP |
| Q34686462 | Cell cycle-dependent regulation of p185neu: a relationship between disruption of this regulation and transformation |
| Q72168972 | Changes of G1 cyclins, cdk2, and cyclin A during the differentiation of HL60 cells induced by TPA |
| Q71672085 | Changes of cell cycle-regulating genes in interferon-treated Daudi cells |
| Q41904203 | Coexpression of cdk2/cdc2 and retinoblastoma gene products in colorectal cancer |
| Q34542215 | Critical Roles of Myc-ODC Axis in the Cellular Transformation Induced by Myeloproliferative Neoplasm-Associated JAK2 V617F Mutant |
| Q33957868 | Cumulative effect of phosphorylation of pRB on regulation of E2F activity. |
| Q35145847 | Cyclin D1 expression is regulated by the retinoblastoma protein |
| Q28647313 | Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation |
| Q34223352 | Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis. |
| Q24651978 | Different roles for cyclins D1 and E in regulation of the G1-to-S transition |
| Q37627255 | Distinct sub-populations of the retinoblastoma protein show a distinct pattern of phosphorylation |
| Q36573000 | Dual Mechanisms for the Inhibition of E2F Binding to RB by Cyclin-Dependent Kinase-Mediated RB Phosphorylation |
| Q36729356 | E1A induces phosphorylation of the retinoblastoma protein independently of direct physical association between the E1A and retinoblastoma products |
| Q35816726 | Enhanced tumor cell growth suppression by an N-terminal truncated retinoblastoma protein |
| Q37636172 | Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences |
| Q39574223 | Functional Inactivation of the Retinoblastoma Protein Requires Sequential Modification by at Least Two Distinct Cyclin-cdk Complexes |
| Q51663666 | Geminin, Ki67, and minichromosome maintenance 2 in gastric hyperplastic polyps, adenomas, and intestinal-type carcinomas: pathobiological significance |
| Q24596103 | Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid system |
| Q35993124 | Hereditary melanoma and the search for the melanoma gene |
| Q24324587 | Identification of G1 kinase activity for cdk6, a novel cyclin D partner |
| Q34452002 | Identification of a candidate tumor suppressor gene RHOBTB1 located at a novel allelic loss region 10q21 in head and neck cancer |
| Q40020347 | Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors |
| Q41655149 | Image analysis quantitation of immunoreactive retinoblastoma protein in human thyroid neoplasms with a streptavidin-biotin-peroxidase staining technique |
| Q73224117 | Immunohistochemical study of Cell Cycle Modulators in G(1)-S Transition in Clinical Breast Cancer Tissue |
| Q24652555 | In vivo association of E2F and DP family proteins |
| Q36634852 | Incomplete penetrance of familial retinoblastoma linked to germ-line mutations that result in partial loss of RB function |
| Q35206804 | Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progression |
| Q36776958 | Interferons and interleukin 6 suppress phosphorylation of the retinoblastoma protein in growth-sensitive hematopoietic cells |
| Q40805644 | Lack of cyclin D-Cdk complexes in Rb-negative cells correlates with high levels of p16INK4/MTS1 tumour suppressor gene product |
| Q33843532 | Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines. |
| Q42088876 | Mitosis-specific phosphorylation of the nuclear oncoproteins Myc and Myb. |
| Q41591490 | Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F |
| Q42030772 | Multiple mechanisms for E2F binding inhibition by phosphorylation of the retinoblastoma protein C-terminal domain |
| Q40800435 | Negative regulation of transcription in eukaryotes |
| Q36811297 | Nuclear Binding of Purified Retinoblastoma Gene Product Is Determined by Cell Cycle-Regulated Phosphorylation |
| Q35450130 | Nuclear protein phosphorylation and growth control |
| Q40637252 | On the importance of protein phosphorylation in cell cycle control |
| Q45056089 | Overexpression of cellular activity and protein level of protein kinase FA/GSK‐3α correlates with human thyroid tumor cell dedifferentiation |
| Q36824755 | Overproduction of Rb protein after the G1/S boundary causes G2 arrest |
| Q28611435 | P53, cell cycle control and apoptosis: Implications for cancer |
| Q35883128 | Perturbation of the p53 response by human papillomavirus type 16 E7. |
| Q35573568 | Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases |
| Q37169903 | Phosphorylation of the retinoblastoma protein by cdk2 |
| Q33855297 | Phosphorylation-induced conformational changes in the retinoblastoma protein inhibit E2F transactivation domain binding |
| Q36459445 | Protein phosphatases and DNA tumor viruses: transformation through the back door? |
| Q34486361 | Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models |
| Q40392432 | Quercetin-induced growth inhibition and cell death in prostatic carcinoma cells (PC-3) are associated with increase in p21 and hypophosphorylated retinoblastoma proteins expression |
| Q36050995 | Regulation of cell cycle progression and nuclear affinity of the retinoblastoma protein by protein phosphatases. |
| Q28647334 | Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes |
| Q42178734 | Retinoblastoma protein phosphorylation does not require activation of p34CDC2 protein kinase |
| Q33641523 | Retracted: Co-Depletion of Cathepsin B and uPAR Induces G0/G1 Arrest in Glioma via FOXO3a Mediated p27Kip1 Upregulation |
| Q37639646 | Senescent cells fail to express cdc2, cycA, and cycB in response to mitogen stimulation |
| Q33338780 | Simian virus 40 large T antigen: the puzzle, the pieces, and the emerging picture |
| Q34995472 | Site-specific hyperphosphorylation of pRb in HIV-induced neurotoxicity |
| Q36659274 | Specific enzymatic dephosphorylation of the retinoblastoma protein |
| Q41252190 | Stem-cell factor regulates the expression of cyclin A and retinoblastoma gene product in the growth and differentiation pathway of human megakaryocytic cells |
| Q36151923 | Structure-function analysis of the retinoblastoma tumor suppressor protein - is the whole a sum of its parts? |
| Q34314510 | Study of the role of retinoblastoma protein in terminal differentiation of murine erythroleukemia cells |
| Q34302524 | The B-domain lysine patch of pRB is required for binding to large T antigen and release of E2F by phosphorylation |
| Q33826493 | The H3K27me3 demethylase dUTX is a suppressor of Notch- and Rb-dependent tumors in Drosophila |
| Q36564503 | The Rb family contains a conserved cyclin-dependent-kinase-regulated transcriptional repressor motif |
| Q36644993 | The adenovirus E1A-associated kinase consists of cyclin E-p33cdk2 and cyclin A-p33cdk2. |
| Q24306341 | The amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers for RNA processing |
| Q40733277 | The cell cycle and the retinoblastoma protein family |
| Q24324203 | The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis |
| Q33604667 | The paramyxovirus simian virus 5 V protein slows progression of the cell cycle |
| Q38306731 | The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulator |
| Q24564605 | The retinoblastoma protein is phosphorylated on multiple sites by human cdc2 |
| Q36962414 | The retinoblastoma protein physically associates with the human cdc2 kinase |
| Q36860853 | The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression |
| Q36643356 | The transcription factor E2F-1 mediates the autoregulation of RB gene expression |
| Q36945529 | Thymidine kinase transcription is regulated at G1/S phase by a complex that contains retinoblastoma-like protein and a cdc2 kinase |
| Q36821079 | Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene |
| Q37585411 | Transformed mammalian cells are deficient in kinase-mediated control of progression through the G1 phase of the cell cycle |
| Q37373014 | Transforming growth factor beta 1 (TGF beta 1) reduces cellular levels of p34cdc2, and this effect is abrogated by adenovirus independently of the E1A-associated pRB binding activity |
| Q36646526 | Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases |
| Q34081405 | Tumor promotion by caspase-resistant retinoblastoma protein |
| Q40568049 | Tumor suppressor genes and their roles in breast cancer |
| Q37399260 | p34cdc2 kinase activity is maintained upon activation of the replication checkpoint in Schizosaccharomyces pombe |
| Q24301099 | p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosis |
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