| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1988Sci...242.1563H |
| P356 | DOI | 10.1126/SCIENCE.3201247 |
| P698 | PubMed publication ID | 3201247 |
| P2093 | author name string | Lee EY | |
| Lee WH | |||
| Friedmann T | |||
| Chen PL | |||
| Huang HJ | |||
| Bookstein R | |||
| Yee JK | |||
| Shew JY | |||
| P2860 | cites work | Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus | Q42798600 |
| P433 | issue | 4885 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | phenotype | Q104053 |
| P304 | page(s) | 1563-1566 | |
| P577 | publication date | 1988-12-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells | |
| P478 | volume | 242 |
| Q37086450 | 1990 Richardson Lecture — Challenges for Neurology in the Nineties: Will We Survive? |
| Q42822876 | 2-Methoxy-4-vinylphenol can induce cell cycle arrest by blocking the hyper-phosphorylation of retinoblastoma protein in benzo[a]pyrene-treated NIH3T3 cells |
| Q36693833 | A bipartite nuclear localization signal in the retinoblastoma gene product and its importance for biological activity |
| Q47878080 | A c-rasHa mutation in the metastasis of a human papillomavirus (HPV)-18 positive penile squamous cell carcinoma suggests a cooperative effect between HPV-18 and c-rasHa activation in malignant progression |
| Q34091691 | A cellular protein that competes with SV40 T antigen for binding to the retinoblastoma gene product |
| Q36547966 | A model for tumor suppression using H-1 parvovirus |
| Q52537791 | A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo |
| Q24648784 | A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock |
| Q28588691 | A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2 |
| Q44891457 | A rare combination consisting of aldosterone-producing adenoma and adrenal myelolipoma in a patient with heterozygosity for retinoblastoma (RB) gene |
| Q24322385 | A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability |
| Q40911289 | A role of inhibin as a tumor suppressor in Sertoli cells: down-regulation upon aging and repression by a viral oncogene |
| Q33779824 | A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding |
| Q24635232 | ANX7, a candidate tumor suppressor gene for prostate cancer |
| Q40958157 | Abnormalities of retinoblastoma gene expression in hematological malignancies |
| Q59073576 | Abrogation by c-myc of G1 phase arrest induced by RB protein but not by p53 |
| Q41634068 | Abundance and state of phosphorylation of the retinoblastoma susceptibility gene product in human colon cancer |
| Q41118589 | Activity of the retinoblastoma family proteins, pRB, p107, and p130, during cellular proliferation and differentiation |
| Q64382296 | Adenoviral Constructs Encoding Phosphorylation-Competent Full-length and Truncated Forms of the Human Retinoblastoma Protein Inhibit Myocyte Proliferation and Neointima Formation |
| Q44623752 | Adenoviral delivery of a constitutively active retinoblastoma mutant inhibits neointima formation in a human explant model for vein graft disease |
| Q38286311 | Adenovirus E1A directly targets the E2F/DP-1 complex |
| Q37016112 | Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product |
| Q45879938 | Adenovirus-mediated retinoblastoma gene therapy suppresses spontaneous pituitary melanotroph tumors in Rb+/- mice |
| Q40524547 | Advances in cancer gene therapy |
| Q33772796 | Allele loss on chromosome 16 associated with progression of human hepatocellular carcinoma |
| Q33889515 | Allelic loss of chromosomes 16q and 10q in human prostate cancer |
| Q68330516 | Allelotyping of human prostatic adenocarcinoma |
| Q35830971 | Altered expression of proliferation and differentiation markers in human papillomavirus 16 and 18 immortalized epithelial cells grown in organotypic culture |
| Q36081670 | Altered patterns of retinoblastoma gene product expression in adult soft-tissue sarcomas |
| Q35848104 | An activity specified by the osteosarcoma line U2OS can substitute functionally for ICP0, a major regulatory protein of herpes simplex virus type 1 |
| Q72549036 | An association of the RB gene with osteosarcoma: molecular genetic evaluation of a case of hereditary retinoblastoma |
| Q27663961 | An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein |
| Q37929978 | An overview of tumor biology |
| Q48035681 | Analysis of chromosome abnormalities by comparative genomic hybridization in malignant peripheral primitive neuroectodermal tumor of the ovary |
| Q35168751 | Angiogenesis: A mechanism by which oncogenes and tumor suppressor genes regulate tumorigenesis |
| Q36748190 | Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides |
| Q28237050 | Antioncogenes and human cancer |
| Q30656298 | Antisense RNA-mediated deficiency of the calpain protease, nCL-4, in NIH3T3 cells is associated with neoplastic transformation and tumorigenesis |
| Q40944245 | Antisense oncogene and tumor suppressor gene therapy of cancer |
| Q35454954 | Approaches to gene therapy of complex multigenic diseases: cancer as a model and implications for cardiovascular disease and diabetes |
| Q35921644 | Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways |
| Q33899583 | Avian reovirus p17 and σA act cooperatively to downregulate Akt by suppressing mTORC2 and CDK2/cyclin A2 and upregulating proteasome PSMB6. |
| Q24317326 | Binding of an interferon-inducible protein (p202) to the retinoblastoma protein |
| Q33548216 | Binding of p110 retinoblastoma protein inhibits nuclear import of simian virus SV40 large tumor antigen |
| Q36793131 | Binding of p53 and p105-RB is not sufficient for oncogenic transformation by a hybrid polyomavirus-simian virus 40 large T antigen |
| Q28255705 | Binding of pRB to the PHD protein RBP2 promotes cellular differentiation |
| Q36706168 | Biological function of the retinoblastoma protein requires distinct domains for hyperphosphorylation and transcription factor binding |
| Q37300676 | Breast cancer stem cells and tumor suppressor genes |
| Q37654636 | C-terminal truncation of the retinoblastoma gene product leads to functional inactivation |
| Q39990000 | CMF1-Rb interaction promotes myogenesis in avian skeletal myoblasts |
| Q40456064 | Cancer gene therapy: principles, problems, and perspectives. |
| Q26828818 | Cancer: we should not forget the past |
| Q37876439 | Cell‐cycle checkpoint for transition from cell division to differentiation |
| Q48013768 | Changes in retinoblastoma gene expression during cervical cancer progression |
| Q41610423 | Characterization of the mucin differentiation in human lung adenocarcinoma cell lines |
| Q40857868 | Choosing anticancer drug targets in the postgenomic era. |
| Q72033662 | Chromosome evolution in retinoblastoma |
| Q22253280 | Cloning and characterization of a novel Kruppel-associated box family transcriptional repressor that interacts with the retinoblastoma gene product, RB |
| Q73384038 | Collective inhibition of pRB family proteins by phosphorylation in cells with p16INK4a loss or cyclin E overexpression |
| Q33248487 | Contributions of differential p53 expression in the spontaneous immortalization of a chicken embryo fibroblast cell line |
| Q36684664 | Control of junB and extracellular matrix protein expression by transforming growth factor-beta 1 is independent of simian virus 40 T antigen-sensitive growth-sensitive growth-inhibitory events |
| Q37559305 | Correlation between retinoblastoma gene expression and differentiation in human testicular tumors |
| Q34814710 | Current Update on Retinoblastoma |
| Q52584077 | Cyclin D3 action in androgen receptor regulation and prostate cancer. |
| Q22008677 | Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest |
| Q42633290 | Cyclin encoded by KS herpesvirus |
| Q37912952 | Cytogenetic abnormalities in cancer: with special emphasis on tumor heterogeneity |
| Q40418811 | Cytogenetics and molecular genetics of human solid tumours |
| Q24308888 | Decreased expression of Mac-2 (carbohydrate binding protein 35) and loss of its nuclear localization are associated with the neoplastic progression of colon carcinoma |
| Q37173111 | Defining the molecular mechanisms of human cell immortalization |
| Q24304934 | Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product |
| Q38332737 | Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation |
| Q39606496 | Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7. |
| Q34660653 | Delivery of inhibitor of growth 4 (ING4) gene significantly inhibits proliferation and invasion and promotes apoptosis of human osteosarcoma cells. |
| Q40470907 | Delta24-hyCD adenovirus suppresses glioma growth in vivo by combining oncolysis and chemosensitization. |
| Q41349328 | Detection of a novel cell cycle-regulated kinase activity that associates with the amino terminus of the retinoblastoma protein in G2/M phases |
| Q34570404 | Diagnosis and current management of retinoblastoma |
| Q52237401 | Differences in patterns of allelic loss between two common types of adult cancer, breast and colon carcinoma, and Wilms' tumor of childhood |
| Q24651899 | Differential roles of two tandem E2F sites in repression of the human p107 promoter by retinoblastoma and p107 proteins |
| Q33571036 | Disruption of RB/E2F-1 interaction by single point mutations in E2F-1 enhances S-phase entry and apoptosis |
| Q37500489 | Distinct and site-specific phosphorylation of the retinoblastoma protein at serine 612 in differentiated cells |
| Q34436312 | Domains of E1A that bind p105Rb, p130, and p300 are required to block nerve growth factor-induced neurite growth in PC12 cells |
| Q24304570 | Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast |
| Q36439907 | E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product |
| Q35837977 | E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. |
| Q40641013 | Early gene responses to transforming growth factor-beta in cells lacking growth-suppressive RB function |
| Q29619196 | Effects of an Rb mutation in the mouse |
| Q36081683 | Effects of transforming growth factor beta-1 on growth-regulatory genes in tumour-derived human oral keratinocytes |
| Q36634983 | Efficient gene transfer into nondividing cells by adeno-associated virus-based vectors. |
| Q36114970 | Enhanced expression of the urokinase-type plasminogen activator gene and reduced colony formation in soft agar by ectopic expression of PU.1 in HT1080 human fibrosarcoma cells |
| Q35816726 | Enhanced tumor cell growth suppression by an N-terminal truncated retinoblastoma protein |
| Q35127787 | Enhanced tumour cell nuclear targeting in a tumour progression model |
| Q40690543 | Epidemiology, etiology, and fertility drugs in ovarian epithelial carcinoma: where are we today? |
| Q41630798 | Establishment of an osteogenic cell line derived from adult mouse bone marrow stroma by use of a recombinant retrovirus |
| Q42801645 | Exogenous E2F expression is growth inhibitory before, during, and after cellular transformation |
| Q37734495 | Expression and state of phosphorylation of the retinoblastoma susceptibility gene product in cycling and noncycling human hematopoietic cells. |
| Q29620009 | Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties |
| Q36453905 | Expression of activated oncogenes in the murine mammary gland: transgenic models for human breast cancer |
| Q33181041 | Expression of p57(KIP2) potently blocks the growth of human astrocytomas and induces cell senescence |
| Q40940257 | Expression of von Hippel-Lindau protein in normal and pathological human tissues |
| Q36679234 | Expression of wild-type p53 is not compatible with continued growth of p53-negative tumor cells |
| Q37636172 | Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences |
| Q41205116 | Familial factors associated with malignant gliomas |
| Q59034709 | For our eyes only |
| Q58862231 | Four separate regions on chromosome 17 show loss of heterozygosity in familial breast carcinomas |
| Q72087899 | Frequent loss of 11p13 and 11p15 loci in male germ cell tumours |
| Q36686649 | From growth arrest to growth suppression |
| Q31122268 | Fte-1, a v-fos transformation effector gene, encodes the mammalian homologue of a yeast gene involved in protein import into mitochondria |
| Q34935982 | Functional cloning of a tumor suppressor gene, TSLC1, in human non-small cell lung cancer |
| Q35034193 | Functional in vitro assays for the isolation of cell transformation effector and suppressor genes |
| Q35218956 | Further characterization of retinoblastoma gene-mediated cell growth and tumor suppression in human cancer cells |
| Q37564092 | G1 arrest and down-regulation of cyclin E/cyclin-dependent kinase 2 by the protein kinase inhibitor staurosporine are dependent on the retinoblastoma protein in the bladder carcinoma cell line 5637. |
| Q51211746 | Gene ecology: a cis-acting gene-to-gene interaction due to the spatial arrangement of genes in chromosomes affects neighbouring transfected c-H-ras expression |
| Q42122076 | Gene therapy for cancers |
| Q34996908 | Gene therapy for genetic and acquired retinal diseases |
| Q45775033 | Gene transfer of herpes simplex virus type I thymidine kinase gene as a drug sensitivity gene into human lung cancer cell lines using retroviral vectors |
| Q28248701 | Genes associated with tumor suppression and growth control in the human nervous system |
| Q44282195 | Genetic Driver Events in Premalignancy: LOH Validated for Marking the Risk of Oral Cancer |
| Q41017427 | Genetic alterations in esophageal cancer and their relevance to etiology and pathogenesis: a review |
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| Q35195221 | Homozygotes for the autosomal dominant neoplasia syndrome (MEN1). |
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| Q36293187 | How do retinoblastoma tumours form? |
| Q35540170 | How the other half lives, the amino‐terminal domain of the retinoblastoma tumor suppressor protein |
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| Q29620442 | Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product |
| Q39882060 | Identification of domains within the human cytomegalovirus major immediate-early 86-kilodalton protein and the retinoblastoma protein required for physical and functional interaction with each other |
| Q33295655 | Identification of genes associated with tumor suppression in Syrian hamster embryo cells |
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| Q41961964 | Induction of DNA synthesis and apoptosis by regulated inactivation of a temperature-sensitive retinoblastoma protein |
| Q43866798 | Infection of cells with replication deficient adenovirus induces cell cycle alterations and leads to downregulation of E2F-1. |
| Q40656395 | Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein |
| Q37693927 | Inhibition of apoptosis by the retinoblastoma gene product. |
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| Q40916266 | Interaction between the pRb2/p130 C-terminal domain and the N-terminal portion of cyclin D3. |
| Q34580759 | Interactions of SV40 large T antigen and other viral proteins with retinoblastoma tumour suppressor |
| Q37112615 | Interferon alpha induces the expression of retinoblastoma gene product in human Burkitt lymphoma Daudi cells: role in growth regulation |
| Q41217469 | Interleukin-1 induces growth arrest by hypophosphorylation of the retinoblastoma susceptibility gene product RB. |
| Q42793095 | Interleukin-2-dependent phosphorylation of the retinoblastoma-susceptibility-gene product p110-115RB in human T-cells |
| Q41003753 | Introduction of a normal retinoblastoma (Rb) gene into Rb-deficient lymphoblastoid cells delays tumorigenicity in immunodefective mice |
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| Q41182258 | Mechanisms responsible for the limited lifespan and immortal phenotypes in cultured mammalian cells |
| Q29619200 | Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis |
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| Q40951665 | Mutation and cancer: a personal odyssey |
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| Q36726394 | Nerve growth factor (NGF) induces neuronal differentiation in neuroblastoma cells transfected with the NGF receptor cDNA. |
| Q48795524 | Neuronal Cdc2-like kinase (Nclk) binds and phosphorylates the retinoblastoma protein |
| Q54169975 | New aspects of cell biology in osteosarcoma |
| Q37671224 | New insights into the causes of cancer. |
| Q37362243 | Nonhomologous chromatid exchange in hereditary and sporadic renal cell carcinomas |
| Q41146343 | Nonrandom chromosome losses in tumorigenic revertants of hybrids between isogeneic immortal and neoplastic human uroepithelial cells |
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| Q35450130 | Nuclear protein phosphorylation and growth control |
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| Q45887791 | Overexpression of E2F‐1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo |
| Q36824755 | Overproduction of Rb protein after the G1/S boundary causes G2 arrest |
| Q37169903 | Phosphorylation of the retinoblastoma protein by cdk2 |
| Q33336307 | Positive selection of candidate tumor-suppressor genes by subtractive hybridization |
| Q36958660 | Prohibitin, an evolutionarily conserved intracellular protein that blocks DNA synthesis in normal fibroblasts and HeLa cells |
| Q33829814 | Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma |
| Q41958239 | Proto-oncogene FBI-1 (Pokemon/ZBTB7A) represses transcription of the tumor suppressor Rb gene via binding competition with Sp1 and recruitment of co-repressors |
| Q24323073 | Purification and characterization of human papillomavirus type 16 E7 protein with preferential binding capacity to the underphosphorylated form of retinoblastoma gene product |
| Q36579239 | RB, the conductor that orchestrates life, death and differentiation |
| Q36455160 | RB-mediated suppression of spontaneous multiple neuroendocrine neoplasia and lung metastases in Rb+/- mice |
| Q36950978 | RB1, Development, and Cancer |
| Q34236628 | RB·E2F1 complex mediates DNA damage responses through transcriptional regulation of ZBRK1. |
| Q33900128 | Rb function in cell-cycle regulation and apoptosis |
| Q21245735 | Rb induces a proliferative arrest and curtails Brn-2 expression in retinoblastoma cells |
| Q44083876 | Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G1 arrest associated with induction of p16ink4a and activation of RB. |
| Q41641448 | Recent advances in bone sarcomas |
| Q41488826 | Recent insights into the functions of the retinoblastoma susceptibility gene product |
| Q28768566 | Recombinant DNA and surgery |
| Q42135076 | Regulated expression of the RB “tumor suppressor gene” in normal lymphocyte mitogenesis: Elevated expression in transformed leukocytes and role as a “status quo” gene |
| Q28343122 | Regulation of C-myc protooncogene expression in osteoblastic cells by arachidonic acid metabolites: Relationship to proliferation |
| Q36050995 | Regulation of cell cycle progression and nuclear affinity of the retinoblastoma protein by protein phosphatases. |
| Q36255480 | Regulation of growth and differentiation in Dictyostelium |
| Q40882566 | Regulation of transcription by proteins that control the cell cycle |
| Q42445498 | Retinoblastoma (Rb) protein upregulates expression of the Ifi202 gene encoding an interferon-inducible negative regulator of cell growth |
| Q41080352 | Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase |
| Q42807149 | Retinoblastoma cell lines Y79, RB355 and WERI-Rb27 are genetically related |
| Q73821364 | Retinoblastoma expression in thyroid neoplasms |
| Q52593006 | Retinoblastoma in an Adult |
| Q40886490 | Retinoblastoma protein and the cell cycle. |
| Q34153888 | Retinoblastoma tumor suppressor and genome stability |
| Q24291241 | Retinoblastoma-binding protein 2 (Rbp2) potentiates nuclear hormone receptor-mediated transcription |
| Q34088329 | Retinoblastoma-related proteins in plants: homologues or orthologues of their metazoan counterparts? |
| Q44391111 | Retinoblastoma: messenger RNA for interphotoreceptor retinoid binding protein |
| Q40459592 | Retroviral transfer of HSV1-TK gene into human lung cancer cell line. |
| Q33958096 | Reversible tumorigenesis induced by deficiency of vasodilator-stimulated phosphoprotein |
| Q24558740 | Rhabdomyosarcoma-associated locus and MYOD1 are syntenic but separate loci on the short arm of human chromosome 11 |
| Q37157253 | Role of Kaposi's sarcoma-associated herpesvirus C-terminal LANA chromosome binding in episome persistence |
| Q34246832 | Role of the retinoblastoma gene in the initiation and progression of human cancer |
| Q36486953 | Role of the retinoblastoma gene in the oncogenesis of human breast carcinoma |
| Q44326870 | Search for putative suppressor genes in meningioma: significance of chromosome 22 |
| Q43649378 | Sequential two-step cleavage of the retinoblastoma protein by caspase-3/-7 during etoposide-induced apoptosis |
| Q42633203 | Shared role of the pRB-related p130 and p107 proteins in limb development |
| Q38304665 | Signaling pathways involved in megakaryocyte-mediated proliferation of osteoblast lineage cells |
| Q36802646 | Simian virus 40 T antigen can transcriptionally activate and mediate viral DNA replication in cells which lack the retinoblastoma susceptibility gene product |
| Q36797245 | Simian virus 40 can overcome the antiproliferative effect of wild-type p53 in the absence of stable large T antigen-p53 binding |
| Q39595418 | Simian virus 40 large T antigen J domain and Rb-binding motif are sufficient to block apoptosis induced by growth factor withdrawal in a neural stem cell line |
| Q24540435 | Skip interacts with the retinoblastoma tumor suppressor and inhibits its transcriptional repression activity |
| Q55093679 | Specific growth inhibition of small-cell lung cancer cells by adenovirus vector expressing antisense c-kit transcripts. |
| Q42383785 | Stability of critical genetic lesions in human colorectal carcinoma xenografts |
| Q35187190 | Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth |
| Q40918854 | Stable overexpression of MEN1 suppresses tumorigenicity of RAS. |
| Q41252190 | Stem-cell factor regulates the expression of cyclin A and retinoblastoma gene product in the growth and differentiation pathway of human megakaryocytic cells |
| Q41526922 | Strategies for Approaching Retinoblastoma Tumor Suppressor Gene Therapy |
| Q37802611 | Stromelysin in tumor progression and metastasis |
| Q40832625 | Structural and functional contributions to the G1 blocking action of the retinoblastoma protein. (the 1992 Gordon Hamilton Fairley Memorial Lecture). |
| Q27630171 | Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen |
| Q27737280 | Structural similarity between the pocket region of retinoblastoma tumour suppressor and the cyclin-box |
| Q34291500 | Structure of the human retinoblastoma gene |
| Q27748910 | Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7 |
| Q36696534 | Suppression of anchorage-independent growth after gene transfection |
| Q41817655 | Suppression of properties associated with malignancy in murine melanoma-melanocyte hybrid cells |
| Q77844575 | Suppression of the neoplastic phenotype by transfection of phospholipase C beta 3 to neuroendocrine tumor cells |
| Q41736072 | Suppression of the progression phenotype in somatic cell hybrids occurs in the absence of altered adenovirus type 5 gene expression |
| Q36292987 | Suppression of tumorigenic and metastatic potentials of human melanoma cell lines by mutated (143 Val-Ala) p53 |
| Q37387858 | Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region |
| Q41526826 | Targeted Tumor Cytotoxicity Mediated by Intracellular Single-Chain Anti-oncogene Antibodies |
| Q35769154 | Targeted tumor killing via an intracellular antibody against erbB-2. |
| Q35138543 | Targeting Rb inactivation in cancers by synthetic lethality |
| Q40722479 | The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis. |
| Q41528803 | The Retinoblastoma Protein: A Master Regulator of Cell Cycle, Differentiation and Apoptosis |
| Q92410942 | The Role of RB in Prostate Cancer Progression |
| Q38334727 | The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein |
| Q36828715 | The ability of simian virus 40 large T antigen to immortalize primary mouse embryo fibroblasts cosegregates with its ability to bind to p53. |
| Q40733277 | The cell cycle and the retinoblastoma protein family |
| Q41264756 | The cellular and molecular pathogenesis of colorectal cancer |
| Q35016771 | The cooperative effect of p53 and Rb in local nanotherapy in a rabbit VX2 model of hepatocellular carcinoma |
| Q37956454 | The current state of oncogenes and cancer: experimental approaches for analyzing oncogenetic events in human cancer |
| Q39943823 | The extreme COOH terminus of the retinoblastoma tumor suppressor protein pRb is required for phosphorylation on Thr-373 and activation of E2F. |
| Q41488498 | The fraction of cells in G1 with bound retinoblastoma protein increases with the duration of the cell cycle |
| Q36081587 | The genetics of breast and ovarian cancer |
| Q70117697 | The genetics of retinoblastoma |
| Q37671253 | The genetics of retinoblastoma. Relevance to the patient |
| Q40867777 | The molecular and genetic characterization of human soft tissue tumors. |
| Q36554273 | The molecular genetics of meningiomas |
| Q30486894 | The ninth Gordon Hamilton-Fairley memorial lecture. Hereditary cancers: clues to mechanisms of carcinogenesis |
| Q24296000 | The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations |
| Q40696376 | The retinoblastoma gene and its significance |
| Q37532549 | The retinoblastoma gene functions as a growth and tumor suppressor in human bladder carcinoma cells |
| Q38306731 | The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulator |
| Q34973639 | The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein |
| Q38015271 | The retinoblastoma gene: its role in human malignancies |
| Q24321861 | The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest |
| Q24320199 | The retinoblastoma protein binds to a family of E2F transcription factors |
| Q37229099 | The retinoblastoma protein tumor suppressor is important for appropriate osteoblast differentiation and bone development |
| Q41139639 | The retinoblastoma susceptibility gene RB-1 in multiple myeloma |
| Q34161991 | The retinoblastoma tumour suppressor in development and cancer |
| Q35951725 | The role of the retinoblastoma gene in tumour pathogenesis |
| Q36555869 | The role of ‘tumor suppressor’ genes in neural tumors |
| Q42220063 | The second Bagshawe lecture. Matching basic research to the management of cancer: the view from the other side of the fence |
| Q36566621 | The transcription factor E2F-1 is a downstream target of RB action |
| Q36643356 | The transcription factor E2F-1 mediates the autoregulation of RB gene expression |
| Q24290817 | The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination |
| Q24568331 | Transcriptional activation by Myc is under negative control by the transcription factor AP-2 |
| Q30531012 | Transient analysis for antiproliferative gene activity |
| Q41625163 | Tumor Suppressor Genes and Human Cancer |
| Q47948675 | Tumor Suppressor Genes: Prospects for Cancer Therapies |
| Q67556469 | Tumor suppressor genes |
| Q37289549 | Tumor suppressor genes and cancer of the human nervous system |
| Q40568049 | Tumor suppressor genes and their roles in breast cancer |
| Q40568235 | Tumor suppressor genes in molecular medicine |
| Q36183682 | Tumor suppressor genes in the cell cycle |
| Q36847017 | Tumor suppressor genes: a new era for molecular genetic studies of cancer |
| Q30499489 | Tumor-suppressor genes: cardinal factors in inherited predisposition to human cancers |
| Q69215743 | Tumour suppressor genes |
| Q28299493 | Tumour suppressor genes in disease and therapy |
| Q41409406 | Tumour-suppressor genes in prostatic oncogenesis: a positional approach |
| Q24304378 | Two ZNF509 (ZBTB49) isoforms induce cell-cycle arrest by activating transcription of p21/CDKN1A and RB upon exposure to genotoxic stress |
| Q24658040 | Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling |
| Q24337366 | Two distinct and frequently mutated regions of retinoblastoma protein are required for binding to SV40 T antigen |
| Q27932248 | Uncoupling the Roles of the SUV3 Helicase in Maintenance of Mitochondrial Genome Stability and RNA Degradation |
| Q34254691 | p53 functions as a cell cycle control protein in osteosarcomas |
| Q45875725 | p53 gene therapy modulates signal transduction in the apoptotic and cell cycle pathways downregulating neointimal hyperplasia. |
| Q36690312 | p53 mutations are not selected for in simian virus 40 T-antigen-induced tumors from transgenic mice |
| Q34618968 | p53 regulates the minimal promoter of the human topoisomerase IIalpha gene |
| Q41014337 | p53-independent induction of WAF1/Cip1 is correlated with osteoblastic differentiation by vitamin D3 |
| Q52165868 | pRB and p107 have distinct effects when expressed in pRB-deficient tumor cells at physiologically relevant levels |
| Q37588543 | pRb, a local chromatin organizer with global possibilities |
| Q40766756 | pRb-expressing adenovirus Ad5-Rb attenuates the p53-induced apoptosis in cervical cancer cell lines. |
| Q43952951 | pRb2/p130 protein expression is correlated with clinicopathologic findings in patients with oral squamous cell carcinoma |
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