scholarly article | Q13442814 |
review article | Q7318358 |
P2093 | author name string | A G Knudson | |
P2860 | cites work | Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis | Q22122362 |
The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity | Q24299515 | ||
Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2 | Q24313491 | ||
Specific chromosome defect associated with human small-cell lung cancer; deletion 3p(14-23) | Q72916321 | ||
The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor suppressor | Q24316544 | ||
The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins | Q24324729 | ||
Mendelian inheritance of familial prostate cancer | Q24562051 | ||
Mutation and cancer: statistical study of retinoblastoma | Q24618185 | ||
A genetic model for colorectal tumorigenesis | Q27860582 | ||
Developmental defects in Gorlin syndrome related to a putative tumor suppressor gene on chromosome 9 | Q28181962 | ||
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus | Q28236741 | ||
Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping | Q28236877 | ||
Clustering of features of von Hippel-Lindau syndrome: evidence for a complex genetic locus | Q28242901 | ||
Genetic mapping of a locus predisposing to human colorectal cancer | Q28268634 | ||
Linkage of early-onset familial breast cancer to chromosome 17q21 | Q28268902 | ||
Identification of a chromosome 18q gene that is altered in colorectal cancers | Q28274172 | ||
APC mutations occur early during colorectal tumorigenesis | Q28274764 | ||
A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations | Q28300121 | ||
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients | Q28300256 | ||
The neurofibromatosis type 1 gene encodes a protein related to GAP | Q28301160 | ||
WT-1 is required for early kidney development | Q28512266 | ||
The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system | Q28513603 | ||
The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21 | Q28609120 | ||
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours | Q29547697 | ||
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene | Q29616490 | ||
Participation of p53 protein in the cellular response to DNA damage | Q29618319 | ||
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms | Q29618586 | ||
Identification of the von Hippel-Lindau disease tumor suppressor gene | Q29618644 | ||
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma | Q29618817 | ||
Effects of an Rb mutation in the mouse | Q29619196 | ||
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis | Q29619200 | ||
Identification and characterization of the familial adenomatous polyposis coli gene | Q29620382 | ||
Microsatellite instability in cancer of the proximal colon | Q29620692 | ||
Homozygous deletion of the alpha- and beta 1-interferon genes in human leukemia and derived cell lines | Q30502375 | ||
Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis | Q30531015 | ||
Abnormalities in structure and expression of the human retinoblastoma gene in SCLC. | Q33825340 | ||
Mapping the gene for hereditary cutaneous malignant melanoma-dysplastic nevus to chromosome 1p. | Q34046828 | ||
Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients | Q34166560 | ||
Mutation and cancer: a model for Wilms' tumor of the kidney | Q34207334 | ||
Deletion of genes on chromosome 1 in endocrine neoplasia | Q57436791 | ||
Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour | Q59088779 | ||
No room at the p53 inn | Q59093958 | ||
Proliferative patterns in colonic mucosa in familial polyposis | Q66908731 | ||
Retinoblastoma: a prototypic hereditary neoplasm | Q67312912 | ||
Chromosomal deletion and retinoblastoma | Q67839651 | ||
Cytogenetic survey of 32 cancers of the prostate | Q70732843 | ||
Homozygous deletion and frequent allelic loss of chromosome 8p22 loci in human prostate cancer | Q72092571 | ||
Clonal expansion of p53 mutant cells is associated with brain tumour progression | Q34233614 | ||
p53 functions as a cell cycle control protein in osteosarcomas | Q34254691 | ||
Expression of recessive alleles by chromosomal mechanisms in retinoblastoma | Q34264957 | ||
Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A. | Q34334980 | ||
A general theory of carcinogenesis | Q34744320 | ||
Neuroblastoma consensus deletion maps to 1p36.1-2. | Q35175544 | ||
Constitutional 1p36 deletion in a child with neuroblastoma. | Q35194318 | ||
Molecular definition of a chromosome 9p21 germ-line deletion in a woman with multiple melanomas and a plexiform neurofibroma: implications for 9p tumor-suppressor gene(s). | Q35194574 | ||
Familial Wiedemann-Beckwith syndrome and a second Wilms tumor locus both map to 11p15.5. | Q35248366 | ||
Mutation and cancer: neuroblastoma and pheochromocytoma | Q35569133 | ||
Stem cell regulation, tissue ontogeny, and oncogenic events | Q35757499 | ||
Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer | Q36046507 | ||
The APC gene product in normal and tumor cells | Q36203064 | ||
Susceptibility to renal carcinoma in the Eker rat involves a tumor suppressor gene on chromosome 10 | Q36506484 | ||
High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene | Q36760672 | ||
Homozygous deletions within human chromosome band 9p21 in melanoma | Q37286548 | ||
Model for the incidence of embryonal cancers: application to retinoblastoma | Q37587021 | ||
p53 and the Li-Fraumeni syndrome | Q40910310 | ||
Molecular characterization of the retinoblastoma susceptibility gene | Q40912798 | ||
Chromosomal aberrations in human neuroblastomas | Q41057218 | ||
Loss of NF1 alleles in phaeochromocytomas from patients with type I neurofibromatosis | Q41093150 | ||
Molecular and cytogenetic analysis of tumors in von Recklinghausen neurofibromatosis | Q41163434 | ||
Molecular genetic analysis of tumors in von Recklinghausen neurofibromatosis: loss of heterozygosity for chromosome 17. | Q41278990 | ||
Structural evidence for the authenticity of the human retinoblastoma gene | Q41344591 | ||
Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells | Q41407134 | ||
Disruption of insulin-like growth factor 2 imprinting in Beckwith-Wiedemann syndrome | Q41523994 | ||
Homozygous loss of the interferon genes defines the critical region on 9p that is deleted in lung cancers | Q41553700 | ||
Persistent expression of the tumor suppressor gene DCC is essential for neuronal differentiation | Q41605307 | ||
Guanine nucleotide biosynthesis is regulated by the cellular p53 concentration | Q41652292 | ||
Nonrandom structural and numerical chromosome changes in non-small-cell lung cancer | Q41686852 | ||
Hereditary Renal-Cell Carcinoma Associated with a Chromosomal Translocation | Q41751694 | ||
Clues to the pathogenesis of familial colorectal cancer | Q42622043 | ||
Rhabdomyosarcoma in children: epidemiologic study and identification of a familial cancer syndrome | Q44178518 | ||
Requirement for a functional Rb-1 gene in murine development | Q44462954 | ||
Loss of heterozygosity for 10q loci in human gliomas | Q46637661 | ||
Familial brain tumour | Q48097571 | ||
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma | Q48100816 | ||
A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor | Q48129277 | ||
Constitutional translocation t(1;17)(p36;q12-21) in a patient with neuroblastoma | Q49170554 | ||
Sporadic bilateral retinoblastoma and 13q- chromosomal deletion | Q52310601 | ||
p53: a frequent target for genetic abnormalities in lung cancer. | Q52486321 | ||
Relaxation of imprinted genes in human cancer. | Q52545355 | ||
Association between wild type and mutant APC gene products. | Q54655882 | ||
Inactivation of both APC alleles in an early stage of colon adenomas in a patient with familial adenomatous polyposis (FAP). | Q54674142 | ||
Absence of IFNA and IFNB genes from human malignant glioma cell lines and lack of correlation with cellular sensitivity to interferons. | Q55484718 | ||
A child with 18q- syndrome and cerebellar astrocytoma. | Q55489119 | ||
A linked genetic marker for multiple endocrine neoplasia type 2A on chromosome 10 | Q55670968 | ||
Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome | Q57266956 | ||
P433 | issue | 23 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | tumor suppressor gene | Q422445 |
neoplasm | Q1216998 | ||
cancer | Q12078 | ||
P304 | page(s) | 10914-10921 | |
P577 | publication date | 1993-12-01 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Antioncogenes and human cancer | |
P478 | volume | 90 |
Q42065532 | 11q13 allelic imbalance discriminates pulmonary carcinoids from tumorlets. A microdissection-based genotyping approach useful in clinical practice |
Q35360684 | 5'-CpG island methylation of the LKB1/STK11 promoter and allelic loss at chromosome 19p13.3 in sporadic colorectal cancer |
Q74127799 | A GTG to ATG novel point mutation at codon 804 in exon 14 of the RET proto-oncogene in two families affected by familial medullary thyroid carcinoma |
Q81483199 | A descriptive study of second primary malignancies associated to breast cancer in a mexican Hispanic population |
Q71244330 | A family inheriting different subtypes of acute myelogenous leukemia |
Q72127267 | A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer |
Q41141673 | A new cell line from human undifferentiated carcinoma of the ovary: establishment and characterization |
Q74583090 | A novel case of infantile sacral teratoma and a constitutional t(12;15)(q13;q25) pat |
Q55172667 | A novel somatic mutation in the RET proto-oncogene in familial medullary thyroid carcinoma with a germline codon 768 mutation. |
Q30715214 | A p53 homologue and a novel serine proteinase inhibitor are over-expressed in lung squamous cell carcinoma |
Q26858878 | A periodic table for cancer |
Q41484383 | A qualitative and quantitative protein database approach identifies individual and groups of functionally related proteins that are differentially regulated in simian virus 40 (SV40) transformed human keratinocytes: an overview of the functional cha |
Q24563121 | A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3 |
Q34053160 | A review of the genetic and related effects of 1,3-butadiene in rodents and humans |
Q36222472 | A second major native von Hippel-Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor. |
Q29977757 | APM-1, a novel human gene, identified by aberrant co-transcription with papillomavirus oncogenes in a cervical carcinoma cell line, encodes a BTB/POZ-zinc finger protein with growth inhibitory activity |
Q24309625 | Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B |
Q52549071 | Allele-specific replication associated with aneuploidy in blood cells of patients with hematologic malignancies. |
Q40969242 | Alleletyping of an oligodendrocyte-type-2 astrocyte lineage derive from a human glioblastoma multiforme |
Q73429863 | Allelic Losses from Chromosome 17 in Human Osteosarcomas |
Q73718063 | Allelic imbalance in colorectal cancer at the CRAC1 locus in early-onset colorectal cancer |
Q34134938 | Allelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers |
Q36694764 | Allelic loss at 19q12 and Xq11-12 predict an adverse clinical outcome in patients with mucinous ovarian tumours of low malignant potential |
Q39836086 | Allelic loss at PTEN locus leads to progression of colorectal carcinoma among North Indian patients |
Q84912254 | Allelic loss of 10q23.3, the PTEN gene locus in cervical carcinoma from Northern Indian population |
Q45923538 | Allelic loss of 6q25-27, the PARKIN tumor suppressor gene locus, in cervical carcinoma. |
Q43839577 | Allelic loss of chromosome 3p24 correlates with tumor progression rather than with retinoic acid receptor beta2 expression in breast carcinoma |
Q73780135 | Allelotype analysis of gallbladder carcinoma associated with anomalous junction of pancreaticobiliary duct |
Q73940404 | Allelotype analysis of intrahepatic cholangiocarcinoma |
Q42442038 | Alteration of the PATCHED locus in superficial bladder cancer |
Q28238279 | Alterations in the PITSLRE protein kinase gene complex on chromosome 1p36 in childhood neuroblastoma |
Q36438383 | Alterations of p16-pRb pathway and chromosome locus 9p21-22 in sporadic invasive breast carcinomas. |
Q36445614 | Alterations of the p16-pRb pathway and the chromosome locus 9p21-22 in non-small-cell lung carcinomas: relationship with p53 and MDM2 protein expression |
Q41122958 | Alterations of the p16INK4A gene in human ovarian cancers |
Q74360528 | Alterations of the tumour suppressor gene DCC in neuroblastoma |
Q77668112 | Altered expression of the growth and transformation suppressor PML gene in human hepatocellular carcinomas and in hepatitis tissues |
Q28213694 | Alternative splicing of the imprinted candidate tumor suppressor gene ZAC regulates its antiproliferative and DNA binding activities |
Q34385809 | An alternative route for multistep tumorigenesis in a novel case of hereditary renal cell cancer and a t(2;3)(q35;q21) chromosome translocation |
Q36568051 | An immunohistochemical study of retinoblastoma gene product in normal, premalignant and malignant tissues of the uterine cervix |
Q34306030 | An infant with Down syndrome and retinoblastoma. A possible non-fortuitous association |
Q33853496 | Anecdotal, historical and critical commentaries on genetics. Rudolph Virchow and the genetic basis of somatic ecology |
Q30656298 | Antisense RNA-mediated deficiency of the calpain protease, nCL-4, in NIH3T3 cells is associated with neoplastic transformation and tumorigenesis |
Q43715475 | Assays to predict the genotoxicity of the chromosomal mutagen etoposide -- focussing on the best assay |
Q58604423 | BRCA1/BRCA2 Mutations Shaped by Ancient Consanguinity Practice in Southern Mediterranean Populations |
Q40848953 | Biological indices in the assessment of breast cancer |
Q31132987 | Bone marrow stromal cell-derived growth inhibitor inhibits growth and migration of breast cancer cells via induction of cell cycle arrest and apoptosis |
Q40971362 | Both the rate and spectrum of loss of heterozygosity differ between human lymphoblastoid cells derived from various donors |
Q42910617 | Break-induced loss of heterozygosity in fission yeast: dual roles for homologous recombination in promoting translocations and preventing de novo telomere addition |
Q44437998 | Bromate induces loss of heterozygosity in the Thymidine kinase gene of L5178Y/Tk+/−-3.7.2C mouse lymphoma cells |
Q73747396 | CTG triplet repeat expansion in a laryngeal carcinoma from a patient with myotonic dystrophy |
Q36080985 | Cancer in the offspring of survivors of childhood leukaemia and non-Hodgkin lymphomas |
Q35038054 | Cancer stem cells and side population cells in breast cancer and metastasis. |
Q36797674 | Carcinogen-induced loss of heterozygosity at the Aprt locus in somatic cells of the mouse |
Q41228037 | Carcinogenesis: basic principles |
Q93035890 | Case report: recurrent pituitary adenoma has increased load of somatic variants |
Q46742483 | Cell biology: Developmental predisposition to cancer |
Q46923351 | Cervical intraepithelial neoplasia III shows frequent allelic loss in 3p and 6p. |
Q24317659 | Characterization of the VHL tumor suppressor gene product: localization, complex formation, and the effect of natural inactivating mutations |
Q73738916 | Characterization of the methylation-sensitive promoter of the imprinted ZAC gene supports its role in transient neonatal diabetes mellitus |
Q42258874 | Chromosomal instability and human cancer |
Q44470570 | Chromosomal region 15q21.1 is a frequent target of allelic imbalance in advanced breast carcinomas |
Q35644518 | Chromosome 9p deletions in cutaneous malignant melanoma tumors: the minimal deleted region involves markers outside the p16 (CDKN2) gene. |
Q41069648 | Chromosome loss with concomitant duplication and recombination both contribute most to loss of heterozygosity in vitro |
Q33220432 | Clonal divergence and genetic heterogeneity in clear cell renal cell carcinomas with sarcomatoid transformation |
Q24291548 | Cloning and characterization of F-LANa, upregulated in human liver cancer |
Q35903086 | Codominant interference, antieffectors, and multitarget drugs |
Q57191694 | Colorectal cancer |
Q33307857 | Comparison of gene expression profiles altered by comfrey and riddelliine in rat liver |
Q43585295 | Comparison of hprt and lacI mutant frequency with DNA adduct formation in N-hydroxy-2-acetylaminofluorene-treated Big Blue rats |
Q34776622 | Comprehensive genetic analysis of cancer cells. |
Q36309515 | Conditional deletion of menin results in antral G cell hyperplasia and hypergastrinemia |
Q33682281 | Congenital anomalies and genetic disorders in families of children with central nervous system tumours |
Q55388589 | Contribution of Chromosome 9p21‐22 Deletion to the Progression of Human Renal Cell Carcinoma |
Q40865275 | Cooperation between AP1 and PEA3 sites within the progression elevated gene-3 (PEG-3) promoter regulate basal and differential expression of PEG-3 during progression of the oncogenic phenotype in transformed rat embryo cells |
Q72781894 | Cooperative tumorigenic effects of germline mutations in Rb and p53 |
Q41164531 | Curable and non-curable malignancies: lessons from paediatric cancer |
Q35965005 | Current issues in genetic toxicology testing for microbiologists |
Q33890654 | Cytogenetic and Molecular Evaluation in Myelodysplastic Syndrome and in Acute and Chronic Leukemia |
Q40659528 | Cytogenetics and cytology of retinoblastomas |
Q35033232 | Cytokine therapeutics: lessons from interferon alpha |
Q41345492 | DCC's function takes shape in the nervous system |
Q23910292 | DLC-1 operates as a tumor suppressor gene in human non-small cell lung carcinomas |
Q34793031 | DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms |
Q40629831 | DNA repair. DNA surveillance defect in cancer cells |
Q36497091 | Decreased expression of the gut-enriched Krüppel-like factor gene in intestinal adenomas of multiple intestinal neoplasia mice and in colonic adenomas of familial adenomatous polyposis patients |
Q47322892 | Deletion of chromosomal region 13q14.3 in childhood acute lymphoblastic leukemia |
Q53402021 | Determination of loss of heterozygosity in frozen and paraffin embedded tumors by denaturating high-performance liquid chromatography (DHPLC). |
Q36865644 | Differential screening of a human chromosome 3 library identifies hepatocyte growth factor-like/macrophage-stimulating protein and its receptor in injured lung. Possible implications for neuroendocrine cell survival |
Q34093068 | Differentiation therapy of human cancer: basic science and clinical applications |
Q33863070 | Disabled-2 inactivation is an early step in ovarian tumorigenicity |
Q34157665 | Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia |
Q54166237 | Distinct genetic loci control development of benign and malignant skin tumours in mice |
Q33818861 | Drosophila in cancer research. An expanding role. |
Q35080493 | Efficiency of carcinogenesis with and without a mutator mutation |
Q39996922 | Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells |
Q74535838 | Enlarging tongue masses in neurofibromatosis type 1: MR findings of two cases |
Q23923048 | Ethnic differences in cancer incidence: a marker for inherited susceptibility? |
Q71167724 | Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers |
Q42542809 | Evolution from heterozygous to homozygous KIT mutation in gastrointestinal stromal tumor correlates with the mechanism of mitotic nondisjunction and significant tumor progression. |
Q24535960 | Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice |
Q37019357 | Evolutionary dynamics of BRCA1 alterations in breast tumorigenesis |
Q36986424 | Evolutionary dynamics of tumor suppressor gene inactivation. |
Q40405380 | Expression and regulation of cyclin genes in breast cancer |
Q54763062 | Extensive analysis of the 13q14 region in human prostate tumors: DNA analysis and quantitative expression of genes lying in the interval of deletion. |
Q37636172 | Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences |
Q24555213 | FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis |
Q42268671 | Failed gene conversion leads to extensive end processing and chromosomal rearrangements in fission yeast |
Q28284637 | Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12-q13: evidence for its role as a tumour suppressor gene |
Q48270104 | Familial gliomas. Analysis of six families with cerebral gliomas and without other inheritable syndromes |
Q40410169 | Familial renal cell carcinoma: review of recent molecular genetics |
Q54633363 | Fine allelotyping of Erbb2-induced mammary tumors in mice reveals multiple discontinuous candidate regions of tumor-suppressor loci. |
Q41617058 | Foulds' dangerous idea revisited: the multistep development of tumors 40 years later. |
Q54985765 | Frequent allelic loss at 7p14-15 associated with aggressive histologic types of breast cancer. |
Q54696633 | Frequent deletions at 12q14.3 chromosomal locus in adult acute lymphoblastic leukemia. |
Q71680261 | Frequent loss of chromosome arms 8p and 13q in collecting duct carcinoma (CDC) of the kidney |
Q53401422 | Frequent loss of heterozygosity at the 19p13.3 locus without LKB1/STK11 mutations in human carcinoma metastases to the brain. |
Q40972502 | Genetic alterations in breast cancer. |
Q35085395 | Genetic alterations in cancer as a result of breakage at fragile sites |
Q40553433 | Genetic alterations in prostate adenocarcinoma. |
Q35249770 | Genetic heterogeneity in familial acute myelogenous leukemia: evidence for a second locus at chromosome 16q21-23.2. |
Q34167625 | Genetic screening for multiple endocrine neoplasia syndrome type 1 (MEN-1): when and how |
Q30579902 | Genetic toxicology data in the evaluation of potential human environmental carcinogens |
Q34331502 | Genetic variation in cancer predisposition: mutational decay of a robust genetic control network |
Q34160186 | Genetically engineered rodent models of mammary gland carcinogenesis: an overview |
Q80946836 | Genetics of colorectal cancer |
Q55476381 | Germline mutations of p53 but not p16/CDKN2 or PTEN/MMAC1 tumor suppressor genes predispose to gliomas. The ANOCEF Group. Association des NeuroOncologues d'Expression Française. |
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Q38500276 | Hepatocellular carcinoma cell lines from diethylnitrosamine phenobarbital-treated rats. Characterization and sensitivity to endothall, a protein serine/threonine phosphatase-2A inhibitor |
Q40970549 | Hereditary cancer: two hits revisited |
Q35609575 | Hereditary kidney cancer |
Q33738528 | High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas |
Q24793756 | Homologous Recombination and Its Role in Carcinogenesis |
Q34183753 | Homologous recombination as a mechanism of carcinogenesis |
Q34169118 | Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region. |
Q60589916 | Identification of RUNX1/AML1 as a classical tumor suppressor gene |
Q44348457 | Ikaros is a critical target during simultaneous exposure to X-rays and N-ethyl-N-nitrosourea in mouse T-cell lymphomagenesis. |
Q46054824 | In vitro perturbations of targets in cancer hallmark processes predict rodent chemical carcinogenesis |
Q39709101 | Inbreeding abolishes the effect of parental origin of a mutant Rb-1 allele on pituitary tumorigenesis in mice |
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Q40845470 | Inhibition of DNA synthesis is a potent mechanism by which cytostatic drugs induce homologous recombination in mammalian cells |
Q24336629 | Inhibition of Transcription Elongation by the VHL Tumor Suppressor Protein |
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Q74420090 | Loss of MHC class II inducibility in hyperplastic tissue in Rb-defective mice |
Q36080488 | Loss of expression and loss of heterozygosity in the DCC gene in neoplasms of the human female reproductive tract |
Q40571620 | Loss of expression of ZAC/LOT1 in squamous cell carcinomas of head and neck |
Q57287558 | Loss of expression of the candidate tumor suppressor gene ZAC in breast cancer cell lines and primary tumors |
Q73644178 | Loss of heterozygosity at 3p24-p25 as a prognostic factor in breast cancer |
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Q41083078 | Loss of heterozygosity or: how I learned to stop worrying and love mitotic recombination |
Q41342455 | Loss of neurofibromatosis type I (NF1) gene expression in pheochromocytomas from patients without NF1. |
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Q35883808 | Low-frequency loss of heterozygosity in Moloney murine leukemia virus-induced tumors in BRAKF1/J mice. |
Q24318831 | Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway |
Q55181109 | Mapping of target regions of allelic loss in primary breast cancers to 1-cM intervals on genomic contigs at 6q21 and 6q25.3. |
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Q57275662 | Merlin: hanging tumor suppression on the Rac |
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Q33891465 | Molecular and genetic aspects of lung cancer |
Q40972927 | Molecular biology of leukemia for the clinician |
Q24606677 | Molecular biology of lung cancer |
Q76402656 | Molecular biology of prostate cancer |
Q40922422 | Molecular biology of testicular germ cell tumors: current status |
Q36243996 | Molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases to 1-1.5 Mb and preparation of a PAC-based physical map. |
Q41528285 | Molecular diagnosis of pancreas carcinoma |
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Q40925425 | Molecular genetics of colorectal cancer |
Q36553814 | Mouse mammary tumor virus/v-Ha-ras transgene-induced mammary tumors exhibit strain-specific allelic loss on mouse chromosome 4 |
Q34244318 | Mouse models of neurofibromatosis |
Q28591456 | Mouse tumor model for neurofibromatosis type 1 |
Q79172144 | Multiple endocrine neoplasia type 1 |
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Q24803579 | On evolutionary origin of cancer |
Q44590170 | One allele deletion of the RB1 gene in a case of refractory anemia with del(13)(q12q14): a fluorescence in situ hybridization study of the RB1 gene |
Q35368205 | Our changing view of the genomic landscape of cancer |
Q73429811 | P53 Overexpression as an Indicator of Overall Survival and Response to Treatment in Osteosarcomas |
Q35092834 | PEA3 sites within the progression elevated gene-3 (PEG-3) promoter and mitogen-activated protein kinase contribute to differential PEG-3 expression in Ha-ras and v-raf oncogene transformed rat embryo cells |
Q48190895 | PTEN/MMAC1 mutations in hepatocellular carcinomas: somatic inactivation of both alleles in tumors |
Q35022507 | Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27 |
Q34617395 | Patterns of Cell Division and the Risk of Cancer |
Q41136153 | Pediatric cancer: environmental and genetic aspects |
Q34053035 | Physical mapping of the minimal region of loss in 5q- chromosome |
Q35895460 | Pituitary tumors in patients with MEN1 syndrome. |
Q37285776 | Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene |
Q24561849 | Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene |
Q38361315 | Predominance of the metastatic phenotype in hybrids formed by fusion of mouse and human melanoma clones |
Q78107676 | Prognosis for G1 cell-cycle regulators: useful for predicting course of disease and for assessment of therapy in cancer |
Q44062726 | Progression elevated gene-3, PEG-3, induces genomic instability in rodent and human tumor cells |
Q37229936 | Progression from colorectal adenoma to carcinoma is associated with non-random chromosomal gains as detected by comparative genomic hybridisation |
Q35618973 | Proliferation of mutators in A cell population |
Q49982607 | Quadruple Neoplasms following Radiation Therapy for Congenital Bilateral Retinoblastoma |
Q73447336 | RB protein expression in human endometrial carcinomas--an immunohistochemical study |
Q36455160 | RB-mediated suppression of spontaneous multiple neuroendocrine neoplasia and lung metastases in Rb+/- mice |
Q42789357 | RET proto-oncogene mutations and rearrangements in endocrine diseases |
Q36359897 | RNA-seq analysis of lung adenocarcinomas reveals different gene expression profiles between smoking and nonsmoking patients. |
Q40456228 | Recent advances in the molecular genetics of urogenital tumors |
Q35047240 | Regulation of tumor suppressors by nuclear-cytoplasmic shuttling |
Q77454454 | Replication status as a possible marker for genomic instability in cells originating from genotypes with balanced rearrangements |
Q40171441 | Retinoblastoma and the genetic theory of cancer: an old paradigm trying to survive to the evidence |
Q34002981 | Retinoids and ovarian cancer |
Q33958096 | Reversible tumorigenesis induced by deficiency of vasodilator-stimulated phosphoprotein |
Q36624071 | Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters |
Q33896232 | Risk assessment for possible carcinogens: a critical look |
Q35929538 | Role of BRCA1 and BRCA2 mutations in pancreatic cancer |
Q35113329 | Role of homologous recombination in carcinogenesis. |
Q34999035 | Selection and analysis of spontaneous reciprocal mitotic cross-overs in Saccharomyces cerevisiae |
Q59794873 | Sex Chromosome Effects on Male-Female Differences in Mammals |
Q91592073 | Single-Gene Deletions Contributing to Loss of Heterozygosity in Saccharomyces cerevisiae: Genome-Wide Screens and Reproducibility |
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Q48379390 | Somatic mutations of the PTEN/MMAC1 gene in fifteen Japanese endometrial cancers: evidence for inactivation of both alleles |
Q34611082 | Spontaneous loss of heterozygosity in diploid Saccharomyces cerevisiae cells |
Q40975396 | Stage-specific gene expression during hepatocarcinogenesis in the rat. |
Q35596587 | Stem cell in gastrointestinal structure and neoplastic development |
Q41526922 | Strategies for Approaching Retinoblastoma Tumor Suppressor Gene Therapy |
Q35128582 | Stress alters rates and types of loss of heterozygosity in Candida albicans |
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Q37388054 | The melanoma differentiation associated gene mda-7 suppresses cancer cell growth |
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Q33938140 | Tumour suppressor genes |
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