Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

scientific article published on May 1983

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/0092-8674(83)90344-6
P698PubMed publication ID6678608

P2093author name stringBaltimore D
Mulligan RC
Mann R
P2860cites workIsolation of biologically active ribonucleic acid from sources enriched in ribonucleaseQ26778460
A new technique for the assay of infectivity of human adenovirus 5 DNAQ27860797
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase IQ27860885
SV40-transformed simian cells support the replication of early SV40 mutantsQ28263905
Characteristics of a human cell line transformed by DNA from human adenovirus type 5Q29547863
Isolation and properties of Moloney murine leukemia virus mutants: use of a rapid assay for release of virion reverse transcriptaseQ35237118
Transfer of defective avian tumor virus genomes by a Rous sarcoma virus RNA packaging mutantQ35237388
Construction and isolation of a transmissible retrovirus containing the src gene of Harvey murine sarcoma virus and the thymidine kinase gene of herpes simplex virus type 1Q35241541
Defective retrovirus-like 30S RNA species of rat and mouse cells are infectious if packaged by type C helper virusQ36494740
Virus-Like 30S RNA in Mouse CellsQ36495367
gag-Related polyproteins of Moloney murine leukemia virus: evidence for independent synthesis of glycosylated and unglycosylated formsQ36498177
Evidence for the Identity of Shared 5′-Terminal Sequences Between Genome RNA and Subgenomic mRNA's of B77 Avian Sarcoma VirusQ36505167
Avian oncovirus mutant (SE21Q1b) deficient in genomic RNA: characterization of a deletion in the provirusQ36507479
Adaptation of a Retrovirus as a Eucaryotic Vector Transmitting the Herpes Simplex Virus Thymidine Kinase GeneQ36972460
Interactions of Murine Leukemia Virus Core Components: Characterization of Reverse Transcriptase Packaged in the Absence of 70S Genomic RNAQ37507683
High-molecular-weight RNAs of AKR, NZB, and wild mouse viruses and avian reticuloendotheliosis virus all have similar dimer structuresQ37602288
Analysis of a 5' leader sequence on murine leukemia virus 21S RNA: heteroduplex mapping with long reverse transcriptase productsQ39490825
High frequency of aberrant expression of Moloney murine leukemia virus in clonal infectionsQ39505489
An avian oncovirus mutant (SE 21Q1b) deficient in genomic RNA: Biological and biochemical characterizationQ39523411
Multiple Free Viral DNA Copies in Polyoma Virus-Transformed Mouse Cells Surviving Productive InfectionQ39978361
Form and Function of Retroviral ProvirusesQ40103422
Expression of a Bacterial Gene in Mammalian CellsQ43823296
Structure of viral DNA and RNA in mammalian cells infected with avian sarcoma virusQ45802199
Nucleotide sequence of Moloney murine leukaemia virusQ45805458
Comparison of immature (rapid harvest) and mature Rous sarcoma virus particlesQ45820129
Germ line integration of moloney leukemia virus: effect of homozygosity at the m-mulV locusQ45886973
Chromosomal position and activation of retroviral genomes inserted into the germ line of miceQ53571340
Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequencesQ59064680
49 Rapid DNA isolations for enzymatic and hybridization analysisQ72850821
P4510describes a project that usesPsi-2Q54948492
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcell lineQ21014462
P304page(s)153-159
P577publication date1983-05-01
P1433published inCellQ655814
P1476titleConstruction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus
P478volume33

Reverse relations

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Q36791433Characterization of Moloney murine leukemia virus mutants with single-amino-acid substitutions in the Cys-His box of the nucleocapsid protein
Q36892576Characterization of a Rous sarcoma virus mutant defective in packaging its own genomic RNA: biochemical properties of mutant TK15 and mutant-induced transformants
Q36892564Characterization of a Rous sarcoma virus mutant defective in packaging its own genomic RNA: biological properties of mutant TK15 and mutant-induced transformants
Q41470756Characterization of a replication-competent retrovirus resulting from recombination of packaging and vector sequences
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Q42642255Characterization of cDNAs of spliced HPV-11 E2 mRNA and other HPV mRNAs recovered via retrovirus-mediated gene transfer
Q69809293Characterization of erythropoietin receptor of murine erythroid cells
Q28769653Characterization of hortulanus endogenous murine leukemia virus, an endogenous provirus that encodes an infectious murine leukemia virus of a novel subgroup
Q41697078Characterization of recombinant helper retroviruses from Moloney-based vectors in ecotropic and amphotropic packaging cell lines
Q36795724Characterization of the gag/fusion protein encoded by the defective Duplan retrovirus inducing murine acquired immunodeficiency syndrome
Q37861192Chimeric antigen receptor (CAR)-engineered lymphocytes for cancer therapy
Q34786043Chromosomal and extrachromosomal instability of the cyclin D2 gene is induced by Myc overexpression
Q45829446Chromosomal position or virus mutation permits retrovirus expression in embryonal carcinoma cells
Q44235096Circularization of retroviral genomic RNA and the control of RNA translation, packaging and reverse transcription
Q40623933Circumvention of chemotherapy-induced myelosuppression by transfer of the mdr1 gene
Q45852163Cis elements and trans-acting factors involved in the RNA dimerization of the human immunodeficiency virus HIV-1.
Q41207261Clinical application of somatic gene therapy in inborn errors of metabolism
Q35610300Clinical trials with retrovirus mediated gene therapy--what have we learned?
Q52242510Clonal and systemic analysis of long-term hematopoiesis in the mouse.
Q41358959Clonal fluctuation within the haematopoietic system of mice reconstituted with retrovirus-infected stem cells
Q45888930Clonal gene therapy: transplanted mouse fibroblast clones express human alpha 1-antitrypsin gene in vivo
Q41727860Cloning of adenovirus type 12 E1 genes into a retroviral vector and their differential splicing in mouse cells
Q40254686Co-localization of gammaretroviral RNAs at their transcription site favours co-packaging
Q34634192Co-packaging of non-vector RNAs generates replication-defective retroviral vector particles: a novel approach for blocking retrovirus replication
Q34669645Co-packaging of sense and antisense RNAs: a novel strategy for blocking HIV-1 replication
Q36553712Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice
Q41245271Comparative analysis of five highly conserved target sites within the HIV-1 RNA for their susceptibility to hammerhead ribozyme-mediated cleavage in vitro and in vivo
Q44022852Comparative analysis of retroviral vector expression in mouse embryonal carcinoma cells
Q36669714Comparison of DNA methylation patterns among mouse cell lines by restriction landmark genomic scanning
Q36872014Comparison of expression in hemopoietic cells by retroviral vectors carrying two genes.
Q40600526Complementarity-directed RNA dimer-linkage promotes retroviral recombination in vivo
Q40998383Complementation cell lines for viral vectors to be used in gene therapy
Q34061107Conditional immortalization of mouse myelomonocytic, megakaryocytic and mast cell progenitors by the Hox-2.4 homeobox gene.
Q35796453Conditional transformation of mouse liver epithelial cells. An in vitro model for analysis of genetic events in hepatocarcinogenesis
Q35859374Conformational analysis of the 5' leader and the gag initiation site of Mo-MuLV RNA and allosteric transitions induced by dimerization
Q31830549Conserved transmembrane tyrosine residues of the TCR beta chain are required for TCR expression and function in primary T cells and hybridomas
Q41498351Considerations for the clinical development of cytokine gene-transduced tumor cell vaccines
Q42806029Constitutive interferon expression from retroviral vector
Q36780266Construction and analysis of deletion mutations in the U5 region of Moloney murine leukemia virus: effects on RNA packaging and reverse transcription.
Q34255941Construction and applications of a highly transmissible murine retrovirus shuttle vector
Q48301018Construction and characterization of a packaging cell line for MMTV-based conditional retroviral vectors
Q69827212Construction and characterization of a retroviral vector demonstrating efficient expression of cloned cDNA sequences
Q41157734Construction and characterization of expression systems for the env gene of ts1, a mutant of Moloney murine leukemia virus-TB
Q42479884Construction and hormone regulation of a novel retroviral vector
Q36752974Construction and properties of replication-competent murine retroviral vectors encoding methotrexate resistance
Q40680688Construction of a Helper Cell Line for Avian Reticuloendotheliosis Virus Cloning Vectors
Q36835504Construction of a defective retrovirus containing the human hypoxanthine phosphoribosyltransferase cDNA and its expression in cultured cells and mouse bone marrow
Q40559798Construction of a retroviral cDNA version of the int-1 mammary oncogene and its expression in vitro
Q37577400Construction of a retrovirus capable of transducing and expressing genes in multipotential embryonic cells
Q41159282Construction of adenoviral and retroviral vectors coexpressing the genes encoding the hepatitis B surface antigen and B7-1 protein
Q24655892Construction of recombinant murine retroviruses that express the human T-cell leukemia virus type II and human T-cell lymphotropic virus type III trans activator genes
Q34069096Construction of retroviral vectors with improved safety, gene expression, and versatility.
Q45835763Control of Rous sarcoma virus RNA translation and packaging by the 5' and 3' untranslated sequences
Q30176883Controlled overexpression of selected domains of the P85 subunit of phosphatidylinositol 3-kinase reverts v-Ha-Ras transformation.
Q42606945Correlation between tumorigenicity and expression levels or splicing patterns of transcripts of the human papillomavirus type 16 E6 gene
Q37498960Costimulatory protein B7-1 enhances the cytotoxic T cell response and antibody response to hepatitis B surface antigen
Q43169551Cre-loxP-mediated DNA flip-flop in mammalian cells leading to alternate expression of retrovirally transduced genes
Q28066817Cross- and Co-Packaging of Retroviral RNAs and Their Consequences
Q45743710Crosslink analysis of N-terminal, C-terminal, and N/B determining regions of the Moloney murine leukemia virus capsid protein
Q39149692Current perspectives in the biology of mouse mammary tumour virus
Q42829762Cytochrome P4501A2 constitutively expressed from transduced DNA mediates metabolic activation and DNA-adduct formation of aromatic amine carcinogens in NIH 3T3 cells
Q33836499DNA as therapeutics; an update
Q34241750DNA damage signals through differentially modified E2F1 molecules to induce apoptosis
Q36488623DNA-mediated genetic transformation of mouse embryos and bone marrow--a review
Q68183881Decreased tumorigenicity of a transplantable rat sarcoma following transfer and expression of an IL-2 cDNA
Q40107270Defective hepatitis B virus particles are generated by packaging and reverse transcription of spliced viral RNAs in vivo
Q34320638Definition of a high-affinity Gag recognition structure mediating packaging of a retroviral RNA genome.
Q36839982Definition of regions in human c-myc that are involved in transformation and nuclear localization
Q72965018Definition of the expression of the human carcinoembryonic antigen and non-specific cross-reacting antigen in human breast and lung carcinomas
Q42806402Deletion of the beta-turn/alpha-helix motif at the exon 2/3 boundary of human c-Myc leads to the loss of its immortalizing function
Q35831703Deletions in one domain of the Friend virus-encoded membrane glycoprotein overcome host range restrictions for erythroleukemia.
Q36882543Design of retrovirus vectors for transfer and expression of the human beta-globin gene.
Q33648331Design of vectors for efficient expression of human purine nucleoside phosphorylase in skin fibroblasts from enzyme-deficient humans
Q33932054Detection of receptor-specific murine leukemia virus binding to cells by immunofluorescence analysis
Q45835632Determinants of Abelson murine leukemia virus pathogenesis
Q40607690Determinants of Moloney murine leukemia virus Gag-Pol and genomic RNA proportions
Q40062655Determinants of retrovirus gene expression in embryonal carcinoma cells
Q36623632Determination of the role for CD21 during Epstein-Barr virus infection of B-lymphoblastoid cells.
Q36828208Development and characterization of an Fv-1-sensitive retrovirus-packaging system: single-hit titration kinetics observed in restrictive cells.
Q41074115Development and characterization of cationic liposomes conjugated with HVJ (Sendai virus): reciprocal effect of cationic lipid for in vitro and in vivo gene transfer
Q85995613Development of a cytokine-modified allogeneic whole cell pancreatic cancer vaccine
Q36811215Development of a retroviral vector for inducible expression of transforming growth factor beta 1.
Q40797068Development of a suspension packaging cell line for production of high titre, serum-resistant murine leukemia virus vectors
Q54438081Development of an amphotropic, high-titer retrovirus vector expressing the dihydrofolate reductase gene and conferring methotrexate resistance.
Q40129979Development of avian sarcoma and leukosis virus-based vector-packaging cell lines
Q37149183Development of gene therapy for blood disorders
Q38290277Development of gene transfer technology
Q41523329Development of methods for somatic cell gene therapy directed against viral diseases, using retroviral vectors carrying the murine or human interferon-beta coding sequence: establishment of the antiviral state in human cells
Q40944251Development of retroviral vectors as safe, targeted gene delivery systems
Q52261166Developmental potential and dynamic behavior of hematopoietic stem cells.
Q52255081Developmental stage specificity of the lymphoid V(D)J recombination activity.
Q36632478Differences in CD4 dependence for infectivity of laboratory-adapted and primary patient isolates of human immunodeficiency virus type 1.
Q40117741Different relative expression from two murine leukemia virus long terminal repeats in unintegrated transfected DNA and in integrated retroviral vector proviruses.
Q45757448Differential behavior of the Mo + PyF101 enhancer variant of Moloney murine leukemia virus in rats and mice
Q34191729Differential effects of microenvironmentally presented interleukin 3 versus soluble growth factor on primitive human hematopoietic cells
Q40265750Differential roles of C/EBP beta regulatory domains in specifying MCP-1 and IL-6 transcription
Q52085152Differentiation of PC12 cells with v-src: comparison with nerve growth factor.
Q35616718Differentiation of myeloid cells is accompanied by increased levels of pp60c-src protein and kinase activity
Q41257165Dimerization of retroviral genomic RNAs: structural and functional implications
Q36455818Direct gene therapy for repair of the spinal cord
Q53435589Dispensability of p53 degradation for tumorigenicity and decreased serum requirement of human papillomavirus type 16 E6.
Q41582641Distinct classes of factor-independent mutants can be isolated after retroviral mutagenesis of a human myeloid stem cell line
Q40470208Distinct role for c-kit receptor tyrosine kinase and SgIGSF adhesion molecule in attachment of mast cells to fibroblasts.
Q41722866Domains of human c-myc protein required for autosuppression and cooperation with ras oncogenes are overlapping
Q41683269Dominant positive and negative selection using a hygromycin phosphotransferase-thymidine kinase fusion gene
Q40755894Down-regulation of MHC class I by bovine papillomavirus E5 oncoproteins
Q34259037Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice.
Q36760642Early pre-B-cell transformation induced by the v-fms oncogene in long-term mouse bone marrow cultures
Q36816122Ectopic lymphokine gene expression in human peripheral blood lymphocytes in vivo
Q45858383Effect of dimerization on the conformation of the encapsidation Psi domain of Moloney murine leukemia virus RNA.
Q30474181Effect of hydrophobic mutations in the H2-H3 subdomain of prion protein on stability and conversion in vitro and in vivo.
Q36887920Effect of internal viral sequences on the utility of retroviral vectors
Q36486121Effective inhibition of influenza virus production in cultured cells by external guide sequences and ribonuclease P.
Q36826993Effector domain mutations dissociate p21ras effector function and GTPase-activating protein interaction
Q42326908Effects of an internal transcription unit and its orientation on retrovirus titre and expression
Q46659741Effects of choline and quiescence on Drosophila choline acetyltransferase expression and acetylcholine production by transduced rat fibroblasts
Q34073981Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells
Q38304776Efficiency and selectivity of RNA packaging by Rous sarcoma virus Gag deletion mutants.
Q34592991Efficient and stable expression of recombinant fibronectin polypeptides
Q39604725Efficient c-kit receptor-targeted gene transfer to primary human CD34-selected hematopoietic stem cells
Q41673873Efficient gene transfer and expression in primary B lymphocytes
Q41711534Efficient gene transfer in live mice using a unique retroviral packaging line
Q37490464Efficient immortalization of luminal epithelial cells from human mammary gland by introduction of simian virus 40 large tumor antigen with a recombinant retrovirus
Q37541994Efficient insertion of genes into the mouse germ line via retroviral vectors
Q35605519Efficient recovery and sequencing of mutant genes from mammalian chromosomal DNA
Q40588218Efficient replication of full-length murine leukemia viruses modified at the dimer initiation site regions
Q40518517Efficient replication, integration, and packaging of retroviral vectors with modified long terminal repeats containing the packaging signal
Q54346600Efficient retroviral transfer of a mouse c-myc construct into HL60.
Q36782879Elevated expression of pp60c-src alters a selective morphogenetic property of epithelial cells in vitro without a mitogenic effect
Q33909953Embryonic stem cell virus, a recombinant murine retrovirus with expression in embryonic stem cells
Q35289952Employment of fibroblasts for gene transfer: applications for grafting into the central nervous system
Q36737272Endocytosis via coated pits mediated by glycoprotein receptor in which the cytoplasmic tail is replaced by unrelated sequences
Q41675906Enhanced growth characteristics of hybridoma cells infected with myc- and ras-containing retroviruses
Q40455802Enhanced insulin secretion from engineered 3T3-L1 preadipocytes by induction of cellular differentiation.
Q33897429Enhanced prostacyclin synthesis in endothelial cells by retrovirus-mediated transfer of prostaglandin H synthase cDNA
Q34373796Enhancer sequences of a retroviral vector determine expression of a gene in multipotent hematopoietic progenitors and committed erythroid cells
Q42810400Episomal vectors rapidly and stably produce high-titer recombinant retrovirus
Q43583241Eradication of murine brain tumors by direct inoculation of concentrated high titer-recombinant retrovirus harboring the herpes simplex virus thymidine kinase gene
Q35755192ErbB2 Is Necessary for ErbB4 Ligands to Stimulate Oncogenic Activities in Models of Human Breast Cancer
Q40729129ErbB2 and ErbB3 do not quantitatively modulate ligand-induced ErbB4 tyrosine phosphorylation.
Q40044286Erythropoietin receptor (EpoR)-dependent mitogenicity of spleen focus-forming virus correlates with viral pathogenicity and processing of env protein but not with formation of gp52-EpoR complexes in the endoplasmic reticulum.
Q45883740Escherichia coli DNA contamination in AmpliTaq Gold polymerase interferes with TaqMan analysis of lacZ.
Q41534215Establishment and neurite outgrowth properties of neonatal and adult rat olfactory bulb glial cell lines.
Q42829154Establishment of Schwann cell lines by oncogene transfer
Q41630798Establishment of an osteogenic cell line derived from adult mouse bone marrow stroma by use of a recombinant retrovirus
Q43711622Establishment of megakaryoblastic cell lines by coinfection of Abelson murine leukemia virus and recombinant SV40-retrovirus.
Q36425970Eucaryotic chromosome transfer: production of a murine-specific cosmid library from a neor-linked fragment of murine chromosome 17.
Q37561804Eukaryotic chromosome transfer: linkage of the murine major histocompatibility complex to an inserted dominant selectable marker
Q41581372Evaluation of human carcinoembryonic-antigen (CEA)-transduced and non-transduced murine tumors as potential targets for anti-CEA therapies
Q37127639Evidence for a Ras-dependent extracellular signal-regulated protein kinase (ERK) cascade
Q27486633Evidence for specificity in the encapsidation of Sindbis virus RNAs
Q33573875Evidence that retroviral transduction is mediated by DNA not by RNA.
Q41741318Evidence that the level of the p55 component of the interleukin (IL) 2 receptor can control IL 2 responsiveness in a murine IL 3-dependent cell
Q36887904Evidence that the packaging signal of Moloney murine leukemia virus extends into the gag region
Q24321231Evolutionary conservation of function among mammalian, avian, and viral homologs of the Bcl-2 oncoprotein
Q39874520Exceptional fusogenicity of Chinese hamster ovary cells with murine retroviruses suggests roles for cellular factor(s) and receptor clusters in the membrane fusion process
Q42832459Excision of an integrated provirus by the action of FLP recombinase
Q68167505Exogeneous expression of L-dopa and dopamine in various cell lines following transfer of rat and human tyrosine hydroxylase cDNA: grafting in an animal model of Parkinson's disease
Q33901213Exon trapping: a genetic screen to identify candidate transcribed sequences in cloned mammalian genomic DNA.
Q35526805Experimental and clinical applications of molecular cell biology in nutrition and metabolism
Q38261224Expression and analysis of the polymeric immunoglobulin receptor in Madin-Darby canine kidney cells using retroviral vectors
Q43842081Expression and functional analysis of G protein alpha subunits in S49 lymphoma cells
Q36923439Expression of HLA-DR antigen in human class II mutant B-cell lines by double infection with retrovirus vectors
Q54441070Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors.
Q69876571Expression of a hemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity
Q70365424Expression of a retrovirus encoding human HPRT in mice
Q40064802Expression of active human immunodeficiency virus type 1 protease by noninfectious chimeric virus particles.
Q69249459Expression of an exogenous growth hormone gene by transplantable human epidermal cells
Q36428262Expression of functional human EGF receptor on murine bone marrow cells
Q45247574Expression of functional human interleukin-2 receptors in murine interleukin-3-dependent cells
Q44136225Expression of human adenosine deaminase in murine haematopoietic progenitor cells following retroviral transfer
Q36849892Expression of human adenosine deaminase in murine hematopoietic cells
Q37676406Expression of human adenosine deaminase using a transmissable murine retrovirus vector system
Q33619761Expression of human alpha-globin and mouse/human hybrid beta-globin genes in murine hemopoietic stem cells transduced by recombinant retroviruses
Q42810847Expression of human argininosuccinate synthetase after retroviral-mediated gene transfer
Q41858311Expression of human argininosuccinate synthetase in murine hematopoietic cells in vivo
Q34611661Expression of human class II major histocompatibility complex antigens using retrovirus vectors
Q37594306Expression of human factor IX in rat capillary endothelial cells: toward somatic gene therapy for hemophilia B
Q41530887Expression of human immunodeficiency virus type 1 Nef antigen on the surface of acutely and persistently infected human T cells.
Q37125290Expression of human papilloma virus type 16 E5 protein in amelanotic melanoma cells regulates endo-cellular pH and restores tyrosinase activity
Q42816254Expression of major histocompatibility complex antigens in squamous cell carcinomas of the head and neck: effects of interferon gene transfer
Q54436699Expression of murine ADA cDNA in bacterial and mammalian cells.
Q41536608Expression of p210 bcr/abl increases hematopoietic progenitor cell radiosensitivity.
Q41619396Expression of phosphoenolpyruvate carboxykinase (PEPCK) chimeras in renal epithelial cells. Retention of appropriate physiological responsiveness using enhancerless retroviral vectors
Q41670691Expression of porcine pro-opiomelanocortin in mouse neuroblastoma (Neuro2A) cells: targeting of the foreign neuropeptide to dense-core vesicles
Q28583975Expression of recombinant myelin-associated glycoprotein in primary Schwann cells promotes the initial investment of axons by myelinating Schwann cells
Q33928812Expression of retroviral vectors in transgenic mice obtained by embryo infection
Q41545350Expression of the E.coli 3-methyladenine DNA glycosylase I gene in mammalian cells reduces the toxic and mutagenic effects of methylating agents
Q36808211Expression of the Evi-1 zinc finger gene in 32Dc13 myeloid cells blocks granulocytic differentiation in response to granulocyte colony-stimulating factor
Q34626255Expression of the Saccharomyces cerevisiae glycoprotein invertase in mouse fibroblasts: glycosylation, secretion, and enzymatic activity
Q36787086Expression of the human beta-globin gene after retroviral transfer into murine erythroleukemia cells and human BFU-E cells.
Q42800350Expression of the neomycin-resistance (neo) gene induces alterations in gene expression and metabolism.
Q54227846Expression of the non-structural proteins of parvovirus MVMp from recombinant retroviruses: predominant role of the parvoviral NS-1 product in host cell disturbance.
Q36447654Expression of transduced tropomyosin 1 cDNA suppresses neoplastic growth of cells transformed by the ras oncogene
Q36361923Expression of tumor necrosis factor by different tumor cell lines results either in tumor suppression or augmented metastasis
Q41754082Expression of v-fms and c-fms in the hemopoietic cell line FDC-P1.
Q77576573Expression vectors and delivery systems
Q41448240Expression, cytoskeletal utilization and dimer formation of tropomyosin derived from retroviral-mediated cDNA transfer. Metabolism of tropomyosin from transduced cDNA.
Q38339423Extended minus-strand DNA as template for R-U5-mediated second-strand transfer in recombinational rescue of primer binding site-modified retroviral vectors
Q36532847Extracellular synaptic factors induce clustering of acetylcholine receptors stably expressed in fibroblasts
Q45846747Factors affecting long-term stability of Moloney murine leukemia virus-based vectors
Q45831591Factors involved in production of helper virus-free retrovirus vectors.
Q36799015Failure of human immunodeficiency virus entry and infection in CD4-positive human brain and skin cells
Q34294780Fatal syndrome in mice engrafted with cells producing high levels of the leukemia inhibitory factor
Q48241475Fate and behavior of genetically labeled cerebellar cells after transplantation into mouse cerebellum
Q36220753Fibroblasts transfected with Torpedo acetylcholine receptor beta-, gamma-, and delta-subunit cDNAs express functional receptors when infected with a retroviral alpha recombinant
Q41649141Fixation of mammalian cells for flow cytometric evaluation of DNA content and nuclear immunofluorescence
Q41580966Flow cytometric titration of retroviral expression vectors: comparison of methods for analysis of immunofluorescence histograms derived from cells expressing low antigen levels
Q33567244Fluorescence-activated cell analysis and sorting of viable mammalian cells based on beta-D-galactosidase activity after transduction of Escherichia coli lacZ
Q35196137Foamy virus vectors.
Q45746032Forced recombination of psi-modified murine leukaemia virus-based vectors with murine leukaemia-like and VL30 murine endogenous retroviruses
Q41693626Formation of Noninfectious HIV-1 Virus Particles Lacking a Full-Length Envelope Protein
Q36827701Formation of infectious hybrid virions with gibbon ape leukemia virus and human T-cell leukemia virus retroviral envelope glycoproteins and the gag and pol proteins of Moloney murine leukemia virus
Q48366755Forty years with homologous recombination
Q36944466Frequent hereditable shutdown of murine retrovirus gene expression in murine cell lines
Q34865747Functional analysis and nucleotide sequence of the promoter region of the murine hck gene
Q34333382Functional analysis of a retroviral host-range mutant: altered long terminal repeat sequences allow expression in embryonal carcinoma cells
Q53520259Functional dissociation of transforming genes of human papillomavirus type 16.
Q70464379Functional expression of a cloned I-A beta k gene in B-lymphoma cells
Q41732514Functional expression of dihydropyridine-insensitive calcium channels during PC12 cell differentiation by nerve growth factor (NGF), oncogenic ras, or src tyrosine kinase
Q36214583Functional expression of the polymeric immunoglobulin receptor from cloned cDNA in fibroblasts
Q39605206Fv-4: identification of the defect in Env and the mechanism of resistance to ecotropic murine leukemia virus
Q58327019Gene Transfer Into the Germ Line of Mice and Into Embryonal Carcinoma Stem Cells
Q38289974Gene array analysis reveals a common Runx transcriptional programme controlling cell adhesion and survival
Q39984515Gene delivery by retroviruses
Q41716747Gene delivery to glioma cells in rat brain by grafting of a retrovirus packaging cell line
Q70111454Gene expression in mice after high efficiency retroviral-mediated gene transfer
Q60912540Gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an Alzheimer's disease mouse model
Q64973001Gene isolation by retroviral tagging.
Q43456650Gene overlap results in a viral protein having an RNA binding domain and a major coat protein domain
Q67528501Gene therapy
Q70935363Gene therapy
Q71843696Gene therapy
Q47554885Gene therapy comes of age.
Q60360924Gene therapy for Parkinson's disease
Q64382253Gene therapy for Parkinson's disease
Q38694710Gene therapy for genetic diseases
Q35236239Gene therapy for human inherited disorders: techniques and status
Q45856156Gene therapy for inherited neurological disorders: towards therapeutic intervention in the Lesch-Nyhan syndrome.
Q37610257Gene therapy for malignant brain tumors
Q38364511Gene therapy for primary immunodeficiencies.
Q35652189Gene therapy for vascular diseases
Q45191990Gene therapy in the CNS: intracerebral grafting of genetically modified cells.
Q33217113Gene therapy in the cornea
Q41625113Gene therapy of Duchenne muscular dystrophy.
Q41297688Gene therapy of hepatoma: bystander effects and non-apoptotic cell death induced by thymidine kinase and ganciclovir
Q45876121Gene therapy of malignant brain tumors: a rat glioma line bearing the herpes simplex virus type 1-thymidine kinase gene and wild type retrovirus kills other tumor cells
Q38753904Gene therapy using retrovirus vectors: vector development and biosafety at clinical trials
Q40530271Gene therapy vectors as drug delivery systems
Q34931179Gene therapy with viral vectors
Q38853561Gene therapy: Myth or reality?
Q37942103Gene therapy: current status and future directions
Q26772109Gene therapy: progress and predictions
Q34101058Gene therapy: promises and problems.
Q36161193Gene therapy: twenty-first century medicine
Q35647626Gene transfer and genome-wide insertional mutagenesis by retroviral transduction in fish stem cells
Q37737788Gene transfer by retrovirus-derived shuttle vectors in the generation of murine bispecific monoclonal antibodies.
Q58149730Gene transfer into bovine cells and embryos using replication‐defective retroviral vectors encapsidated with xenotropic murine leukemia virus envelopes
Q44221281Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus, and retrovirus vectors
Q40607279Gene transfer into hematopoietic progenitor and stem cells: progress and problems.
Q35261136Gene transfer into hematopoietic stem cells: prospects for human gene therapy
Q38681713Gene transfer into hemopoietic stem cells using retroviral vectors
Q24647777Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector
Q68877418Gene transfer into humans: a first step
Q38037038Gene transfer into murine hematopoietic stem cells and bone marrow stromal cells
Q38646175Gene transfer into primates and prospects for gene therapy in humans
Q44441663Gene transfer into rat airway epithelial cells using retroviral vectors
Q39581687Gene transfer into the nervous system
Q45775033Gene transfer of herpes simplex virus type I thymidine kinase gene as a drug sensitivity gene into human lung cancer cell lines using retroviral vectors
Q71346908Gene transfer on its long path to therapeutic application
Q35887352Gene transfer to human cells using retrovirus vectors produced by a new polytropic packaging cell line
Q38686576Gene transfer. A potential approach to gene therapy for sickle cell disease
Q59280523Gene-search viruses and FACS-Gal permit the detection, isolation, and characterization of mammalian cells with in situ fusions between cellular genes and Escherichia coli lacZ
Q34094064Generating mice with targeted mutations
Q91942885Generation of High-Titer Self-Inactivated γ-Retroviral Vector Producer Cells
Q36780473Generation of a helper cell line for packaging avian leukosis virus-based vectors.
Q40069386Generation of a high-titer packaging cell line for the production of retroviral vectors in suspension and serum-free media
Q45847956Generation of competent virus in the REV helper cell line C3.
Q36886039Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene
Q40718975Generation of stable retrovirus packaging cell lines after transduction with herpes simplex virus hybrid amplicon vectors
Q34066344Generation of targeted retroviral vectors by using single-chain variable fragment: an approach to in vivo gene delivery
Q39830015Genetic complexity and expression of human class II histocompatibility antigens
Q36744055Genetic definition of ras effector elements
Q33655095Genetic determinants of neoplastic transformation by the retroviral oncogene v-erbB.
Q68724967Genetic engineering of animals
Q64382339Genetic immunotherapy for cancer
Q59599919Genetic manipulation of hematopoietic stem cells with retrovirus vectors
Q53483163Genetic predisposition and mesenchymal-epithelial interactions in ras+myc-induced carcinogenesis in reconstituted mouse prostate.
Q33693779Genetic regulatory elements introduced into neural stem and progenitor cell populations
Q36792561Genetic tagging of tumor cells with retrovirus vectors: clonal analysis of tumor growth and metastasis in vivo
Q40905745Genetic therapy. Past, present, and future
Q37610792Genetically altered and defined cell lines for transplantation in animal models of Parkinson's disease
Q54249393Genomic rearrangements of retroviral vectors carrying two genes in F9 EC cells
Q36453658Genotoxicity of retroviral integration in hematopoietic cells.
Q36759140Germ line c-myc is not down-regulated by loss or exclusion of activating factors in myc-induced macrophage tumors.
Q34189858Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector
Q30468679Globular domain of the prion protein needs to be unlocked by domain swapping to support prion protein conversion
Q41464482Glucokinase expression in rat hepatoma cells induces glucose uptake and is rate limiting in glucose utilization
Q40511076Glycosylation deficiency at either one of the two glycan attachment sites of cellular prion protein preserves susceptibility to bovine spongiform encephalopathy and scrapie infections.
Q41757700Graduated resistance to G418 leads to differential selection of cultured mammalian cells expressing the neo gene
Q34320662Grafting fibroblasts genetically modified to produce L-dopa in a rat model of Parkinson disease
Q43543978Grafting genetically modified cells into the rat brain: characteristics of E. coli beta-galactosidase as a reporter gene
Q37610789Grafting genetically modified cells to the brain: conceptual and technical issues
Q39694407Grafting genetically modified cells to the brain: possibilities for the future
Q43839045Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression
Q72085554Granulocyte colony‐stimulating factor treatment of mice modulates differently the sensitivity of blood and bone marrow hematopoietic progenitors to retroviral vector infection
Q41953353Granulocyte colony-stimulating factor gene transfer suppresses tumorigenicity of a murine adenocarcinoma in vivo
Q67506342Growth factor-like effects mediated by muscarinic receptors in PC12M1 cells
Q41388906Growth inhibition of human glioma cells modulated by retrovirus gene transfection with antisense IL-8.
Q33862904Growth- and tumor-promoting effects of deregulated BCL2 in human B-lymphoblastoid cells
Q36890377H-2Ld antigen encoded by a recombinant retrovirus genome is expressed on the surface of infected cells
Q36641150HGF/SF and its receptor c-MET play a minor role in the dissemination of human B-lymphoma cells in SCID mice
Q34443134HIV-1 Gag-RNA interaction occurs at a perinuclear/centrosomal site; analysis by confocal microscopy and FRET.
Q24301505HLS5, a novel RBCC (ring finger, B box, coiled-coil) family member isolated from a hemopoietic lineage switch, is a candidate tumor suppressor
Q45111676HSV-1 vector mediated neuronal gene delivery. Strategies for molecular neuroscience and neurology
Q34614346Handicapped retroviral vectors efficiently transduce foreign genes into hematopoietic stem cells
Q36362319Hck tyrosine kinase activity modulates tumor necrosis factor production by murine macrophages
Q36876655Heat shock protein hsp70 protects cells from thermal stress even after deletion of its ATP-binding domain
Q36231835Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer
Q41450695Helper virus-free herpes simplex virus-1 plasmid vectors for gene therapy of Parkinson's disease and other neurological disorders
Q35870965Helper virus-free transfer of herpes simplex virus type 1 plasmid vectors into neural cells.
Q36965464Hematologic disease induced in BALB/c mice by a bcr-abl retrovirus is influenced by the infection conditions
Q45889093Hematopoietic stem cells expanded by fibroblast growth factor-1 are excellent targets for retrovirus-mediated gene delivery
Q43997265Hemopoietic lineage switch: v-raf oncogene converts Emu-myc transgenic B cells into macrophages
Q40852248Herpesviruses: expression of genes in postmitotic brain cells
Q54401908High efficiency gene transfer and expression in normal murine B lymphocytes.
Q40823437High expression of human 15-lipoxygenase induces NF-kappaB-mediated expression of vascular cell adhesion molecule 1, intercellular adhesion molecule 1, and T-cell adhesion on human endothelial cells
Q36551618High titers of retrovirus (vesicular stomatitis virus) pseudotypes, at last
Q34611394High-affinity interleukin 2 binding by an oncogenic hybrid interleukin 2-epidermal growth factor receptor molecule
Q68780717High-efficiency gene transfer into cells
Q37572832High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range
Q45885718High-level recombinant gene expression in rabbit endothelial cells transduced by retroviral vectors
Q54375928Highly efficient action of autocrine mouse interferon-gamma expressed via a retroviral vector.
Q33868950Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia
Q33932573Homologous recombination of copackaged retrovirus RNAs during reverse transcription
Q70127247Homology among oncogenes
Q26767304Host RNA Packaging by Retroviruses: A Newly Synthesized Story
Q30195331Host range mutants of v-src: alterations in kinase activity and substrate interactions
Q36215749How retroviruses select their genomes
Q42806237Human beta-globin gene expression after gene transfer using retroviral vectors
Q36799805Human cells infected with retrovirus vectors acquire an endogenous murine provirus
Q70143048Human gene therapy
Q36309600Human gene therapy: present and future
Q40663428Human genetic therapy
Q41376860Human immunodeficiency virus type 2 (HIV-2): packaging signal and associated negative regulatory element
Q41283198Human somatic cell gene therapy
Q41142780Hyperosmolality suppresses but TGF beta 1 increases MMP9 in human peritoneal mesothelial cells
Q41705456IL-6 Production by Retrovirus Packaging Cells and Cultured Bone Marrow Cells
Q36698033Identification and characterization of a coronavirus packaging signal
Q36830945Identification of a doubly spliced viral transcript joining the separated domains for putative protease and reverse transcriptase of hepatitis B virus.
Q67493322Identification of a generalised packaging sequence for D-type retroviruses and generation of a D-type retroviral vector
Q42387383Identification of a high affinity nucleocapsid protein binding element from the bovine leukemia virus genome
Q45734713Identification of a high affinity nucleocapsid protein binding element within the Moloney murine leukemia virus Psi-RNA packaging signal: implications for genome recognition
Q36634317Identification of a sequence in the unique 5' open reading frame of the gene encoding glycosylated Gag which influences the incubation period of neurodegenerative disease induced by a murine retrovirus
Q24645417Identification of a sequence required for efficient packaging of human immunodeficiency virus type 1 RNA into virions
Q40129310Identification of a signal in a murine retrovirus that is sufficient for packaging of nonretroviral RNA into virions
Q36829664Identification of cellular promoters by using a retrovirus promoter trap
Q88917043Identification of conserved, primary sequence motifs that direct retrovirus RNA fate
Q33642167Identification of directly infected cells in the bone marrow of neonatal moloney murine leukemia virus-infected mice by use of a moloney murine leukemia virus-based vector.
Q36923563Identification of protein products encoded by the proto-oncogene int-1
Q38347886Identification of sites that act together to direct dimerization of human foamy virus RNA in vitro.
Q41446266Immortalization of immature and mature mouse astrocytes with SV40 T antigen.
Q33572128Immortalization of mouse neural precursor cells by the c-myc oncogene
Q69119104Immunodeficiency and clonal growth of target cells induced by helper-free defective retrovirus
Q41334777Immunoglobulin heavy chain switch region recombination within a retroviral vector in murine pre-B cells
Q37597644Immunoregulatory activity of the T-cell receptor alpha chain demonstrated by retroviral gene transfer
Q41022147Impaired secretion of the elongated mutant of protein C (protein C-Nagoya). Molecular and cellular basis for hereditary protein C deficiency
Q48159155Implantation of genetically engineered cells to the brain.
Q41064189Improvement of retroviral packaging cell lines by introducing the polyomavirus early region
Q41490944In vitro and in vivo characterisation of glial cells immortalised with a temperature sensitive SV40 T antigen-containing retrovirus.
Q53524994In vitro and in vivo regulation of liver epithelial cells carrying a metallothionein-rasT24 fusion gene.
Q33653475In vitro assembly properties of human immunodeficiency virus type 1 Gag protein lacking the p6 domain.
Q36867600In vitro synthesis of infectious retroviral RNA
Q34347155In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome
Q33670561In vitro-derived leukemic erythroid cell lines induced by a raf- and myc-containing retrovirus differentiate in response to erythropoietin
Q45984137In vivo production and release of acetylcholine from primary fibroblasts genetically modified to express choline acetyltransferase.
Q39581188In vivo selection of Rous sarcoma virus mutants with randomized sequences in the packaging signal
Q27486825Increase of retroviral infection in vitro by the binding of antiretroviral antibodies
Q40671178Increased frequency of N-region insertion in a murine pre-B-cell line infected with a terminal deoxynucleotidyl transferase retroviral expression vector
Q34631459Increased radiation-induced transformation in C3H/10T1/2 cells after transfer of an exogenous c-myc gene
Q33634411Increased tyrosine kinase activity associated with the protein encoded by the activated neu oncogene
Q41525843Increased viral titer through concentration of viral harvests from retroviral packaging lines
Q28345681Independent influence of strain difference and mi transcription factor on the expression of mouse mast cell chymases
Q36852773Individual adenovirus type 5 early region 1A gene products elicit distinct alterations of cellular morphology and gene expression
Q36842787Individual mouse VL30 elements transferred to rat cells by viral pseudotypes retain their responsiveness to activators of protein kinase C.
Q41703408Inducibility of class II major histocompatibility complex antigens by interferon gamma is associated with reduced tumorigenicity in C3H mouse fibroblasts transformed by v-Ki-ras
Q24652685Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae
Q41141469Induction of murine CD5 expression by v-H-ras
Q37601224Induction of plasmacytomas secreting antigen-specific monoclonal antibodies with a retrovirus expressing v-abl and c-myc
Q43812637Induction of plasmacytomas that secrete monoclonal anti-peptide antibodies by retroviral transformation
Q45836665Induction of the autonomous stage of transformation in erythroid cells infected with SFFV: helper virus is not required
Q37535996Induction of the early stages of Friend erythroleukemia with helper-free Friend spleen focus-forming virus
Q37656060Induction of transcription from the long terminal repeat of Moloney murine sarcoma provirus by UV-irradiation, x-irradiation, and phorbol ester
Q54357759Infection of bovine cells of embryonic origin by amphotropic retroviral vectors.
Q37689072Infection of cultured central nervous system neurons with a defective herpes simplex virus 1 vector results in stable expression of Escherichia coli beta-galactosidase
Q41724335Infection with Murine Retrovirus Confers Resistance to the Neurotoxin 1-Methyl-4-Phenylpyridinium Ion in PC12 Cells
Q45085478Infectious and Selectable Retrovirus Containing an Inducible Rat Growth Hormone Minigene
Q30430249Infectious molecular clones with the nonhomologous dimer initiation sequences found in different subtypes of human immunodeficiency virus type 1 can recombine and initiate a spreading infection in vitro.
Q88772902Influence of gag and RRE Sequences on HIV-1 RNA Packaging Signal Structure and Function
Q43842559Influence of the helper virus on expression of beta-galactosidase from a defective HSV-1 vector, pHSVlac
Q41399114Influence of tyrosine residues Y705 and Y807 on the transforming potency of the v-fms oncogene product of feline sarcoma virus
Q28237847Inhibition of HIV-1 multiplication in a human CD4+ lymphocytic cell line expressing antisense and sense RNA molecules containing HIV-1 packaging signal and Rev response element(s)
Q37511861Inhibition of Moloney murine leukemia virus-induced leukemia in transgenic mice expressing antisense RNA complementary to the retroviral packaging sequences
Q40615471Inhibition of breast and ovarian tumor growth through multiple signaling pathways by using retrovirus-mediated small interfering RNA against Her-2/neu gene expression
Q40100354Inhibition of human T-cell leukemia virus type I replication in primary human T cells that express antisense RNA.
Q38333070Inhibition of human immunodeficiency virus type 1 multiplication by antisense and sense RNA expression
Q40199297Inhibition of infectious human immunodeficiency virus type 1 virions via lentiviral vector encoded short antisense RNAs
Q41603934Inhibition of replication of HIV-1 by retroviral vectors expressing tat-antisense and anti-tat ribozyme RNA.
Q42812739Inhibition of the Moloney murine leukemia virus cycle at a post reverse transcriptional step by the netropsin-intercalating hybrid molecule netropsin-oxazolopyridocarbazole
Q37540402Insertion of a bacterial gene into the mouse germ line using an infectious retrovirus vector.
Q39702035Insertion of dominant selectable markers into the human genome
Q44387670Insertion of hypoxanthine phosphoribosyltransferase cDNA into human bone marrow cells by a retrovirus.
Q37536018Insertion of the bacterial gpt gene into the germ line of mice by retroviral infection
Q41455365Insertion of the human cytomegalovirus enhancer into a myeloproliferative sarcoma virus long terminal repeat creates a high-expression retroviral vector
Q40988290Insertion of two independent enhancers in the long terminal repeat of a self-inactivating vector results in high-titer retroviral vectors with tissue-specific expression
Q44140193Insertional mutagenesis by retroviruses and promoter traps in embryonic stem cells
Q44914199Insertional mutagenesis to isolate genes
Q28083335Insights into the nuclear export of murine leukemia virus intron-containing RNA
Q36872242Integration of the BALB/c ecotropic provirus into the colony-stimulating factor-1 growth factor locus in a myc retrovirus-induced murine monocyte tumor
Q41150442Interacting residues in the extracellular region of the common beta subunit of the human granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptors involved in constitutive activation.
Q40959601Interaction between endothelial cells and the secreted cytokine drives the fate of an IL4- or an IL5-transduced tumour
Q54348374Interferon-mediated inhibition of retroviral infection: use of a defective retrovirus carrying a drug-resistance gene.
Q36362418Interleukin 2 activates extracellular signal-regulated protein kinase 2.
Q36231901Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents
Q24339580Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's
Q41486062Interleukin-3 and Bcl-2 cooperatively inhibit etoposide-induced apoptosis in a murine pre-B cell line.
Q40677768Interleukin-7 retroviruses transform pre-B cells by an autocrine mechanism not evident in Abelson murine
Q44534068Internalization of the human immunodeficiency virus does not require the cytoplasmic domain of CD4.
Q45129684Intracerebral grafting of genetically modified cells acting as biological pumps
Q36388622Intranuclear localization of human papillomavirus 16 E7 during transformation and preferential binding of E7 to the Rb family member p130
Q78128999Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus
Q63965567Introduction and Expression of the Interleukin 2 Receptor (Tac) Gene in Hematopoietic Stem Cells with Retrovirus Vectors
Q37577456Introduction of a selectable gene into different animal tissue by a retrovirus recombinant vector
Q54134810Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/Wv mice.
Q35586255Introduction of genes into preimplantation mouse embryos by use of a defective recombinant retrovirus
Q52273129Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse
Q53747308Introduction of sequences encoding functional human adenosine deaminase into mouse cells using a retroviral shuttle system.
Q35063101Invasive drug delivery.
Q41654477Investigation of a possible role of the amino-terminal pro-region of proopiomelanocortin in its processing and targeting to secretory granules
Q41650686Investigation of the mutagenic specificity of X-rays using a retroviral shuttle vector in CHO cells
Q28287538Involvement of SH2-containing phosphotyrosine phosphatase Syp in erythropoietin receptor signal transduction pathways
Q42806933Involvement of mi-transcription factor in expression of alpha-melanocyte-stimulating hormone receptor in cultured mast cells of mice
Q35763983Involvement of transcription factor encoded by the mouse mi locus (MITF) in apoptosis of cultured mast cells induced by removal of interleukin-3
Q36530944Isoform-specific subcellular targeting of glucose transporters in mouse fibroblasts
Q42809755Isoforms of c-KIT differ in activation of signalling pathways and transformation of NIH3T3 fibroblasts
Q36883617Isolation and characterization of NIH 3T3 cells expressing polyomavirus small T antigen.
Q41692064Isolation and characterization of irradiation fusion hybrids from mouse chromosome 1 for mapping Rmc-1, a gene encoding a cellular receptor for MCF class murine retroviruses
Q36949872Isolation of Large T Antigen-Producing Mouse Cell Lines Capable of Supporting Replication of Polyomavirus-Plasmid Recombinants
Q36855313Isolation of a recombinant murine leukemia virus utilizing a new primer tRNA.
Q41685936Isolation of cellular revertants from a rat cell line transformed by the E6 and E7 genes of human papillomavirus type 16
Q36797188Isolation of vascular smooth muscle cell cultures with altered responsiveness to the antiproliferative effect of heparin
Q64516813Joining of VK to JK gene segments in a retroviral vector introduced into lymphoid cells
Q41638615Juxtaglomerular cells cultured on a reconstituted basement membrane
Q42939025Kirsten murine sarcoma virus abolishes interferon gamma-induced class II but not class I major histocompatibility antigen expression in a murine fibroblast line
Q34467839LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress, and perspectives
Q36918344Lack of competition results in efficient packaging of heterologous murine retroviral RNAs and reticuloendotheliosis virus encapsidation-minus RNAs by the reticuloendotheliosis virus helper cell line
Q41217979Lack of tumorigenicity of interleukin 4 autocrine growing cells seems related to the anti-tumor function of interleukin 4.
Q40292793Latent murine leukemia virus infection characterized by the release of non-infectious virions
Q52726162Lentiviral Transduction of Rat Schwann Cells and Dorsal Root Ganglia Neurons for In Vitro Myelination Studies.
Q64057516Lentiviral Vectors as Tools for the Study and Treatment of Glioblastoma
Q45324668Lentiviral vectors and adeno-associated virus vectors: useful tools for gene transfer in pain research
Q38147100Lentiviral vectors for cancer immunotherapy and clinical applications
Q36760023Lentiviral vectors for cancer immunotherapy: transforming infectious particles into therapeutics.
Q24629462Lentiviral vectors in gene therapy: their current status and future potential
Q33290074Library selection and directed evolution approaches to engineering targeted viral vectors
Q34496697Ligand stimulation of ErbB4 and a constitutively-active ErbB4 mutant result in different biological responses in human pancreatic tumor cell lines.
Q38135674Ligand-targeted particulate nanomedicines undergoing clinical evaluation: current status
Q34585324Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer
Q74603312Lineage analysis using retroviral vectors
Q41619715Lineage analysis using retroviral vectors.
Q36754856Lineage analysis using retrovirus vectors
Q41387628Lineage analysis using retrovirus vectors
Q73110159Lineage analysis with retroviral vectors
Q41531133Lines of glial precursor cells immortalised with a temperature-sensitive oncogene give rise to astrocytes and oligodendrocytes following transplantation into demyelinated lesions in the central nervous system
Q24634002Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure
Q68104570Local administration of cells containing an inserted IL-2 gene and producing IL-2 inhibits growth of human tumours in nu/nu mice
Q36710306Localization of sequences required in cis for yeast Ty1 element transposition near the long terminal repeats: analysis of mini-Ty1 elements
Q34578841Long-term exposure to retrovirally expressed granulocyte-colony-stimulating factor induces a nonneoplastic granulocytic and progenitor cell hyperplasia without tissue damage in mice
Q33926209Long-term expression of a T-cell receptor beta-chain gene in mice reconstituted with retrovirus-infected hematopoietic stem cells
Q41187067Long-term expression of gene introduction into normal human T-lymphocytes by retroviral-mediated gene transfer
Q34319569Long-term expression of human adenosine deaminase in mice transplanted with retrovirus-infected hematopoietic stem cells
Q36822821Long-term in vivo expression of genes introduced by retrovirus-mediated transfer into mammary epithelial cells
Q36826874Loss of pathogenicity of spleen focus-forming virus after pseudotyping with Akv
Q33638488Low-affinity placenta-derived receptors for human granulocyte-macrophage colony-stimulating factor can deliver a proliferative signal to murine hemopoietic cells
Q40456084MDR gene transfer into live mice.
Q37481899MTrasT24, a metallothionein-ras fusion gene, modulates expression in cultured rat liver cells of two genes associated with in vivo liver cancer
Q36710324Macrophage lineage switching of murine early pre-B lymphoid cells expressing transduced fms genes
Q69074595Malignant progression of papilloma-derived keratinocytes: differential effects of the ras, neu, and p53 oncogenes
Q53543492Malignant transformation of erythroid cells in vivo by introduction of a nonreplicating retrovirus vector.
Q36883310Mammalian cell transformation by a murine retrovirus vector containing the avian erythroblastosis virus erbB gene
Q45836967Mammalian expression-and-transmission vector derived from Akv murine leukemia virus
Q39750602Mammalian gene transfer and gene expression
Q57271413Manipulating DNA: from Cloning to Knockouts
Q36652049Maturation of dimeric viral RNA of Moloney murine leukemia virus.
Q41635111Measurement of hygromycin B phosphotransferase activity in crude mammalian cell extracts by a simple dot-blot assay
Q36753246Mechanism of autocrine stimulation in hematopoietic cells producing interleukin-3 after retrovirus-mediated gene transfer
Q37904362Micromanipulation of embryos and germ cells: an approach to gene therapy?
Q28295218Microphthalmia-associated transcription factor interacts with PU.1 and c-Fos: determination of their subcellular localization
Q54311159MoMuLV-derived self-inactivating retroviral vectors possessing multiple cloning sites and expressing the resistance to either G418 or hygromycin B.
Q36762877Mock retroviral infection alters the developmental potential of murine bone marrow stem cells
Q38352848Modulation of ecotropic murine retroviruses by N-linked glycosylation of the cell surface receptor/amino acid transporter.
Q34593412Modulation of gene expression in multiple hematopoietic cell lineages following retroviral vector gene transfer
Q45730219Modulation of homo- and heterodimerization of Harvey sarcoma virus RNA by GACG tetraloops and point mutations in palindromic sequences
Q36560927Modulation of thermal induction of hsp70 expression by Ku autoantigen or its individual subunits
Q40832214Molecular approaches to cancer therapy.
Q45201906Molecular basis of alpha 1-antitrypsin deficiency and its potential therapy by gene transfer
Q36586876Molecular genetic characterization of the RD-114 gene family of endogenous feline retroviral sequences
Q39736121Molecular genetics and potential gene therapy
Q46638492Molecular mechanisms of FGF-2 inhibitory activity in the osteogenic context of mouse adipose-derived stem cells (mASCs).
Q39341963Moloney murine leukemia virus genomic RNA packaged in the absence of a full complement of wild type nucleocapsid protein
Q33654203Moloney murine leukemia virus infects cells of the developing hair follicle after neonatal subcutaneous inoculation in mice.
Q33785012Monitoring retroviral RNA dimerization in vivo via hammerhead ribozyme cleavage.
Q41722615Monochromosomal mouse microcell hybrids containing inserted selectable neo genes
Q41745011Monochromosomal rodent-human hybrids from microcell fusion of human lymphoblastoid cells containing an inserted dominant selectable marker
Q45835860Mouse mammary tumor virus mediated transfer and expression of neomycin resistance to infected cultured cells
Q69735738Multi-copy introduction and high-level expression of interleukin-3 genes by retroviral vector superinfection
Q37582808Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection
Q41809902Multilineage hematopoietic disorders induced by transplantation of bone marrow cells expressing the v-fms oncogene
Q37727542Multiple Functional Motifs Are Required for the Tumor Suppressor Activity of a Constitutively-Active ErbB4 Mutant
Q34467477Multiple amino acid residues within the rabbit prion protein inhibit formation of its abnormal isoform
Q41112430Multiple transduction as a means of preserving ganciclovir chemosensitivity in sarcoma cells carrying retrovirally transduced herpes thymidine kinase genes
Q59355961Multiple, Switchable Protein:RNA Interactions Regulate Human Immunodeficiency Virus Type 1 Assembly
Q53516187Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ.
Q42814584Murine leukemia virus maturation: protease region required for conversion from "immature" to "mature" core form and for virus infectivity
Q40818078Murine myeloid cell lines derived by in vitro infection with recombinant c-myb retroviruses express myb from rearranged vector proviruses
Q36657459Murine pluripotent hematopoietic progenitors constitutively expressing a normal erythropoietin receptor proliferate in response to erythropoietin without preferential erythroid cell differentiation
Q45854041Murine retroviral vectors expressing the tax1 gene of human T-cell leukemia virus type 1.
Q42196238Mus spicilegus endogenous retrovirus HEMV uses murine sodium-dependent myo-inositol transporter 1 as a receptor.
Q37198429Musings on genome medicine: gene therapy
Q39509704Mutants of murine leukemia viruses and retroviral replication
Q38314018Mutated primer binding sites interacting with different tRNAs allow efficient murine leukemia virus replication
Q40176579Mutation in the glycosylated gag protein of murine leukemia virus results in reduced in vivo infectivity and a novel defect in viral budding or release
Q40107061Mutational analysis of N-linked glycosylation sites of Friend murine leukemia virus envelope protein
Q36634241Mutational analysis of cis-acting packaging signals in human immunodeficiency virus type 1 RNA.
Q41044335Mutational analysis of stem-loops in the RNA packaging signal of the Moloney murine leukemia virus
Q35828610Mutational analysis of the murine AIDS-defective viral genome reveals a high reversion rate in vivo and a requirement for an intact Pr60gag protein for efficient induction of disease
Q33880314Mutations in the cytoplasmic domain of EGF receptor affect EGF binding and receptor internalization
Q36804927Mutations of RNA and protein sequences involved in human immunodeficiency virus type 1 packaging result in production of noninfectious virus
Q39588854Mutations of the kissing-loop dimerization sequence influence the site specificity of murine leukemia virus recombination in vivo.
Q33681365Myc-induced cyclin D2 genomic instability in murine B cell neoplasms.
Q33330955Myeloproliferative disorder and leukaemia in mice induced by different classes of constitutive mutants of the human IL-3/IL-5/GM-CSF receptor common beta subunit
Q36634970Myristylation of Pr60gag of the murine AIDS-defective virus is required to induce disease and notably for the expansion of its target cells
Q72039728N-nitrosodiethylamine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced morphological transformation of C3H/10T1/2CL8 cells expressing human cytochrome P450 2A6
Q44904852NBP, a protein that specifically binds an enhancer of immunoglobulin gene rearrangement: purification and characterization
Q34283905NF-kappaB1 can inhibit v-Abl-induced lymphoid transformation by functioning as a negative regulator of cyclin D1 expression
Q100424291NMR Studies of Retroviral Genome Packaging
Q40671312Nature and specificity of lymphokine independence induced by a selectable retroviral vector expressing v-src
Q41206626Negative autoregulation of c-myc transcription
Q35891618Negative regulation of granulocytic differentiation in the myeloid precursor cell line 32Dcl3 by ear-2, a mammalian homolog of Drosophila seven-up, and a chimeric leukemogenic gene, AML1/ETO.
Q36375906Negative regulation of phagocytosis in murine macrophages by the Src kinase family member, Fgr.
Q40040268Negative regulation of the 5' long terminal repeat (LTR) by the 3' LTR in the murine proviral genome.
Q51192930Neoplastic transformation and lineage switching of rat liver epithelial cells by retrovirus-associated oncogenes.
Q36782472Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck)
Q41338744Neoplastic transformation of a human bronchial epithelial cell line by a recombinant retrovirus encoding viral Harvey ras.
Q40609652New Structure Sheds Light on Selective HIV-1 Genomic RNA Packaging
Q36838229Nonmitogenic morphoregulatory action of pp60v-src on multicellular epithelial structures
Q40678630Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line
Q34092811Nonrandom packaging of host RNAs in moloney murine leukemia virus
Q42830421Normal human melanocytes that express a bFGF transgene still require exogenous bFGF for growth in vitro
Q36690303Novel GACG-hairpin pair motif in the 5' untranslated region of type C retroviruses related to murine leukemia virus
Q41717906Nuclear localization of c-Fos, but not v-Fos proteins, is controlled by extracellular signals
Q34302330Nucleocapsid protein effects on the specificity of retrovirus RNA encapsidation
Q40530367Nucleotide sequence of mouse virus-like (VL30) retrotransposon BVL-1.
Q40390840On the conformational stability of the smallest RNA kissing complexes maintained through two G·C base pairs
Q39716258On the use of double FLP recognition targets (FRTs) in the LTR of retroviruses for the construction of high producer cell lines
Q69575348Oncogene activation and surface markers in mouse lymphomas induced by radiation and nitrosomethylurea
Q36752903Oncogene cooperation in lymphocyte transformation: malignant conversion of E mu-myc transgenic pre-B cells in vitro is enhanced by v-H-ras or v-raf but not v-abl
Q39532738Oncogenes in transgenic mice
Q42289065Oncogenic activation of the neu-encoded receptor protein by point mutation and deletion
Q34561988Opportunities for the use of lentiviral vectors in human gene therapy
Q33782598Origin and rapid evolution of a novel murine erythroleukemia virus of the spleen focus-forming virus family.
Q33634507Overcoming interference to retroviral superinfection results in amplified expression and transmission of cloned genes
Q38786382Overexpression of mitochondrial Hsp70/Hsp75 protects astrocytes against ischemic injury in vitro.
Q42831651Overexpression of protein kinase C alpha-subtype in Swiss/3T3 fibroblasts causes loss of both high and low affinity receptor numbers for epidermal growth factor
Q41448332Overexpression of protein kinase C beta I in a murine keratinocyte cell line produces effects on cellular growth, morphology and differentiation
Q36723752Overexpression of protein kinase C in HT29 colon cancer cells causes growth inhibition and tumor suppression
Q28571162Overproduction of protein kinase C causes disordered growth control in rat fibroblasts
Q40014482Overview of the retrovirus transduction system
Q40689692PA 317 retrovirus packaging cells
Q36649979Packaging of human immunodeficiency virus type 1 RNA requires cis-acting sequences outside the 5' leader region.
Q40067097Packaging system for rapid production of murine leukemia virus vectors with variable tropism
Q42799687Partial isolation from intact cells of a cell surface-exposed lysophosphatidylinositol-phospholipase C.
Q35996377Peptide antibodies to the human c-fyn gene product demonstrate pp59c-fyn is capable of complex formation with the middle-T antigen of polyomavirus
Q39842422Perspectives for gene therapy: inserting new genetic information into mammalian cells by physical techniques and viral vectors
Q69731655Perspectives on UV light mutagenesis: investigation of the CHO aprt gene carried on a retroviral shuttle vector
Q41760401Phenotypic effects of overexpression of PKC beta 1 in rat liver epithelial cells
Q41627940Photodynamic inactivation of retroviruses by phthalocyanines: the effects of sulphonation, metal ligand and fluoride
Q36811075Ping-pong amplification of a retroviral vector achieves high-level gene expression: human growth hormone production
Q36827892Plasma membrane receptors for ecotropic murine retroviruses require a limiting accessory factor
Q36690316Platelet-derived growth factor receptor can mediate tumorigenic transformation by the bovine papillomavirus E5 protein
Q33669533Point mutants of Moloney murine leukemia virus that fail to package viral RNA: evidence for specific RNA recognition by a "zinc finger-like" protein sequence
Q37624867Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity
Q46151972Polymerase gene products of hepatitis B viruses are required for genomic RNA packaging as well as for reverse transcription
Q44429876Portable encapsidation signal of the L-A double-stranded RNA virus of S. cerevisiae
Q36827825Positive Selectable Markers for Use with Mammalian Cells in Culture
Q33829038Positive genetic selection for gene disruption in mammalian cells by homologous recombination
Q36753045Posttranscriptional regulation of cellular gene expression by the c-myc oncogene
Q37405342Potentiation of growth factor activity by exogenous c-myc expression.
Q41028945Preclinical characterization of an anti-tat ribozyme for therapeutic application
Q41017656Preparation of brain-derived neurotrophic factor- and neurotrophin-3-secreting Schwann cells by infection with a retroviral vector
Q68763779Preproparathyroid hormone. A model for analyzing the secretory pathway
Q36620087Presentation of native epitopes in the V1/V2 and V3 regions of human immunodeficiency virus type 1 gp120 by fusion glycoproteins containing isolated gp120 domains
Q40300058Prion infection influences murine endogenous retrovirus expression in neuronal cells
Q27485991Processing of the intracellular form of the west Nile virus capsid protein by the viral NS2B-NS3 protease: an in vitro study
Q34597261Production of glycosylated physiologically "normal" human alpha 1-antitrypsin by mouse fibroblasts modified by insertion of a human alpha 1-antitrypsin cDNA using a retroviral vector
Q41743293Production of human immunodeficiency virus (HIV)-like particles from cells infected with recombinant vaccinia viruses carrying the gag gene of HIV
Q37263723Production of infectious recombinant Moloney murine leukemia virus particles in BHK cells using Semliki Forest virus-derived RNA expression vectors
Q39989759Production of retroviral vectors
Q42813419Production of spliced DNA copies of the cottontail rabbit papillomavirus genome in a retroviral vector.
Q72583945Production of transgenic mice
Q38646431Progress toward human gene therapy
Q33920752Progress with retroviral gene vectors
Q42808592Progression of rat embryo fibroblast cells immortalized with transforming genes of human papillomavirus type 16
Q72399477Prospects for Human Gene Therapy
Q38237409Prospects for gene therapy now and in the future
Q41302096Prospects for the control of AIDS patients by introducing defective-HIV harbouring leukocytes
Q40851727Prospects for virus-based gene therapy for cystic fibrosis
Q37371051Prostate-specific membrane antigen can promote in vivo osseous metastasis of prostate cancer cells in mice
Q34047697Protamine sulfate as an effective alternative to polybrene in retroviral-mediated gene-transfer: implications for human gene therapy
Q54374665Protection of uninfected human bone marrow cells in long-term culture from G418 toxicity after retroviral-mediated transfer of the NEOr gene.
Q39376269Protective effect of gedunin on TLR-mediated inflammation by modulation of inflammasome activation and cytokine production: Evidence of a multitarget compound
Q36254314Proviral deletions and oncogene base-substitutions in insertionally mutagenized c-myc alleles may contribute to the progression of avian bursal tumors
Q36552332Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogene
Q33928762Pseudotyped retroviral vectors reveal restrictions to reticuloendotheliosis virus replication in rat cells
Q36687863Pseudotyping with human T-cell leukemia virus type I broadens the human immunodeficiency virus host range
Q40036808Quantification and characterization of autotransduction in retroviral vector producer cells
Q42663924R7, a spontaneous mutant of Moloney murine sarcoma virus 124 with three direct repeats and an in-frame truncated gag-mos gene, induces brain lesions
Q24617791RACH2, a novel human gene that complements a fission yeast cell cycle checkpoint mutation
Q30054778RNA is a structural element in retrovirus particles
Q38328360RNA packaging signal of human immunodeficiency virus type 1
Q41100836RNA packaging.
Q41671801RNA secondary structure analysis of the packaging signal for Moloney murine leukemia virus
Q35837228RNA secondary structure and binding sites for gag gene products in the 5' packaging signal of human immunodeficiency virus type 1.
Q35122730RNA sequences in the Moloney murine leukemia virus genome bound by the Gag precursor protein in the yeast three-hybrid system.
Q69799114RNA viruses as gene expression vectors
Q42807566Rapid generation and flow cytometric analysis of stable GFP-expressing cells
Q36808948Rapid titration of retroviral vectors encoding intracellular antigens by flow cytometry
Q34304672Rapidly and slowly replicating human immunodeficiency virus type 1 isolates can be distinguished according to target-cell tropism in T-cell and monocyte cell lines
Q36560567Ras induces anchorage-independent growth by subverting multiple adhesion-regulated cell cycle events
Q41195584Ras is involved in gap junction closure in proliferating fibroblasts or preadipocytes but not in differentiated adipocytes
Q36075500Ras-independent transformation by v-Src
Q34164036Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation
Q41615398Rat cellular mutants for expression of mRNA from the long terminal repeat of murine retrovirus
Q41537234Rat-1 fibroblasts engineered with GAD65 and GAD67 cDNAs in retroviral vectors produce and release GABA.
Q36354503Rearrangement of exogenous immunoglobulin VH and DJH gene segments after retroviral transduction into immature lymphoid cell lines
Q30334504Recombinant DNA approaches for the development of metabolic systems used in in vitro toxicology
Q41319057Recombinant DNA technology: a 20-year occupational health retrospective
Q69206990Recombinant gene expression in vivo within endothelial cells of the arterial wall
Q38482437Recombinant hexahistidine arginine decarboxylase (hisADC) induced endogenous agmatine synthesis during stress
Q41737027Recombinant neutral endopeptidase-24.11 expressed in mouse neuroblastoma cells is associated with neurite membranes
Q35216664Recombinant retrovirus vectors for treatment of malignant brain tumors
Q36874353Recombinant retroviruses encoding cell surface antigens as selectable markers.
Q36912292Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens
Q35610962Recombinant retroviruses that transduce individual polyoma tumor antigens: effects on growth and differentiation
Q36872559Recombinant retroviruses that transduce middle T antigen cDNAs derived from polyomavirus mutants: separation of focus formation and soft-agar growth in transformation assays and correlations with kinase activities in vitro.
Q39579989Recombination in the 5' leader of murine leukemia virus is accurate and influenced by sequence identity with a strong bias toward the kissing-loop dimerization region.
Q74630606Reconstruction of SEA-B7.1 double signals on human hepatocellular carcinoma cells and analysis of its immunological effect
Q36918698Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production
Q45884752Regression of experimental brain tumors with 6-thioxanthine and Escherichia coli gpt gene therapy
Q44439368Regulated expression of HIV-1 Rev function in mammalian cell lines
Q36835645Regulated expression of a complete human beta-globin gene encoded by a transmissible retrovirus vector
Q36802960Regulation of RNA splicing in gag-deficient mutants of Moloney murine sarcoma virus MuSVts110.
Q41888711Regulation of natural antibody binding and susceptibility to natural killer cells through Zn++-inducibleras oncogene expression
Q39504602Regulation of protein synthesis in virus-infected animal cells.
Q35832832Regulation of the differentiation of diploid and some aneuploid rat liver epithelial (stemlike) cells by the hepatic microenvironment
Q43563690Regulation of the efficiency and thermodependence of murine sarcoma virus MuSVts110 RNA splicing by sequences in both exons
Q41109063Release of replication-deficient retroviruses from a packaging cell line: interaction with glioma tumor spheroids in vitro
Q28359721Replication of human immunodeficiency virus 1 and Moloney murine leukemia virus is inhibited by different heteroatom-containing analogs of myristic acid
Q30176895Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling
Q36916742Rescue of type I collagen-deficient phenotype by retroviral-vector-mediated transfer of human pro alpha 1(I) collagen gene into Mov-13 cells
Q36798367Resistance to human immunodeficiency virus type 1 (HIV-1) infection in human CD4+ lymphocyte-derived cell lines conferred by using retroviral vectors expressing an HIV-1 RNA-specific ribozyme.
Q34042038Resistance to human immunodeficiency virus type 1 infection conferred by transduction of human peripheral blood lymphocytes with ribozyme, antisense, or polymeric trans-activation response element constructs.
Q37020060Restoration of normal conduction properties in demyelinated spinal cord axons in the adult rat by transplantation of exogenous Schwann cells
Q37736716Restoration of normal lysosomal function in mucopolysaccharidosis type VII cells by retroviral vector-mediated gene transfer
Q48120641Retinal ganglion cell survival is promoted by genetically modified astrocytes designed to secrete brain-derived neurotrophic factor (BDNF).
Q41673599Retrotransposon gene engineering
Q59350051Retroviral Gag protein-RNA interactions: Implications for specific genomic RNA packaging and virion assembly
Q21131436Retroviral RNA Dimerization and Packaging: The What, How, When, Where, and Why
Q43905715Retroviral RNA packaging: sequence requirements and implications
Q41703713Retroviral Vectors Related to the Myeloproliferative Sarcoma Virus Allow Efficient Expression in Hematopoietic Stem and Precursor Cell Lines, but Retroviral Infection Is Reduced in More Primitive Cells
Q60160315Retroviral Vectors for Gene Transfer
Q41857863Retroviral and lentiviral vectors for the induction of immunological tolerance
Q33931883Retroviral characteristics of the long terminal repeat of murine E.Tn sequences
Q68124839Retroviral envelope protein fusions to secreted and membrane markers
Q42799011Retroviral expression of green fluorescent protein
Q42952364Retroviral expression of the human IL-2 gene in a murine T cell line results in cell growth autonomy and tumorigenicity
Q41719763Retroviral expression of transforming growth factor-alpha does not transform fibroblasts or keratinocytes
Q45858285Retroviral gene therapy in ApoE-deficient mice: ApoE expression in the artery wall reduces early foam cell lesion formation
Q41712927Retroviral gene therapy in hematopoietic diseases
Q69145695Retroviral gene transfer in mice: the use of a unique packaging line improves efficiency
Q40087583Retroviral gene transfer of tissue-type plasminogen activator targets thrombolysis in vitro and in vivo
Q41751072Retroviral gene transfer using safe and efficient packaging cell lines
Q41216939Retroviral interleukin 5 gene transfer into interleukin 5-dependent growing cell lines results in autocrine growth and tumorigenicity
Q45888976Retroviral mediated transfer and expression of human alpha 1-antitrypsin in cultured cells
Q35848783Retroviral nucleocapsid domains mediate the specific recognition of genomic viral RNAs by chimeric Gag polyproteins during RNA packaging in vivo.
Q41640714Retroviral pseudotypes produced by rescue of a moloney murine leukemia virus vector by C-type, but not D-type, retroviruses
Q35848344Retroviral retargeting by envelopes expressing an N-terminal binding domain.
Q45035327Retroviral shuttle vectors as a tool for the study of mutational specificity (base substitution/deletion/mutational hotspot).
Q73666855Retroviral transduction of murine epidermal stem cells demonstrates clonal units of epidermal structure
Q33576574Retroviral transduction of oncogenic sequences involves viral DNA instead of RNA.
Q36752763Retroviral transduction of the human c-Ha-ras-1 oncogene into midgestation mouse embryos promotes rapid epithelial hyperplasia
Q54405796Retroviral transfer and expression of the interleukin-3 gene in hemopoietic cells.
Q40459592Retroviral transfer of HSV1-TK gene into human lung cancer cell line.
Q34304914Retroviral transfer of a human tyrosine hydroxylase cDNA in various cell lines: regulated release of dopamine in mouse anterior pituitary AtT-20 cells
Q33557828Retroviral transfer of a murine cDNA for multidrug resistance confers pleiotropic drug resistance to cells without prior drug selection
Q35612715Retroviral transfer of genes into canine hemopoietic progenitor cells in culture: a model for human gene therapy
Q36919339Retroviral vector gene expression in F9 embryonal carcinoma cells
Q36288912Retroviral vector production in the National Gene Vector Laboratory at Indiana University
Q39025649Retroviral vector production.
Q43579547Retroviral vector-mediated gene transfer into human hematopoietic progenitor cells
Q68303284Retroviral vector-mediated in vivo expression of low-density-lipoprotein receptors in the Watanabe heritable hyperlipidemic rabbit
Q41535083Retroviral vector-mediated transduction of K-ras antisense RNA into human lung cancer cells inhibits expression of the malignant phenotype
Q73121669Retroviral vectors
Q41465135Retroviral vectors containing chimeric promoter/enhancer elements exhibit cell-type-specific gene expression
Q40405683Retroviral vectors displaying functional antibody fragments
Q41744778Retroviral vectors expressing soluble CD4: a potential gene therapy for AIDS.
Q35216654Retroviral vectors for gene delivery to neural precursor cells
Q35303194Retroviral vectors for persistent expression in vivo
Q41751058Retroviral vectors for the beta-globin gene that demonstrate improved titer and expression
Q40944434Retroviral vectors. From laboratory tools to molecular medicine
Q38280077Retroviral vectors: from cancer viruses to therapeutic tools
Q35261336Retroviral vectors: post entry events and genomic alterations
Q52182771Retroviral-mediated expression of an MHC class I-restricted T cell receptor in the CD8 T cell compartment of bone marrow-reconstituted mice.
Q37593042Retroviral-mediated gene therapy for the treatment of hepatocellular carcinoma: an innovative approach for cancer therapy
Q37915230Retroviral-mediated gene transfer
Q33663979Retroviral-mediated gene transfer and expression of human phenylalanine hydroxylase in primary mouse hepatocytes
Q35586549Retroviral-mediated gene transfer of human phenylalanine hydroxylase into NIH 3T3 and hepatoma cells
Q28576254Retroviral-mediated gene transfer of the peripheral myelin protein PMP22 in Schwann cells: modulation of cell growth
Q41555361Retroviral-mediated gene transfer of the porcine choline acetyltransferase: a model to study the synthesis and secretion of acetylcholine in mammalian cells.
Q39338569Retroviral-mediated gene transfer. Applications in neurobiology
Q34614384Retroviral-mediated transfer of genomic globin genes leads to regulated production of RNA and protein
Q35604723Retroviral-mediated transfer of the human glucocerebrosidase gene into cultured Gaucher bone marrow
Q36597697Retrovirus RNA trafficking: from chromatin to invasive genomes
Q36980900Retrovirus Transduction: Generation of Infectious Retroviruses Expressing Dominant and Selectable Genes Is Associated with In Vivo Recombination and Deletion Events
Q39650796Retrovirus mediated gene transfer into hemopoietic cells
Q41724194Retrovirus mediated transfer and expression of GM-CSF in haematopoietic cells
Q40811299Retrovirus molecular conjugates. A novel, high transduction efficiency, potentially safety-improved, gene transfer system
Q37784715Retrovirus packaging cells.
Q36682583Retrovirus promoter-trap vector to induce lacZ gene fusions in mammalian cells
Q36915374Retrovirus shuttle vector for study of kinase activities of pp60c-src synthesized in vitro and overproduced in vivo
Q51239419Retrovirus transfer of a bacterial gene into mouse haematopoietic progenitor cells.
Q41719716Retrovirus vector-targeted inducible expression of human beta-interferon gene to B-cells.
Q39584235Retrovirus vectors and their applications in neurobiology
Q39763606Retrovirus vectors and their uses in molecular biology
Q40115867Retrovirus vectors containing an internal attachment site: evidence that circles are not intermediates to murine retrovirus integration
Q73876718Retrovirus vectors displaying the IgG-binding domain of protein A
Q36457016Retrovirus vectors: toward the plentivirus?
Q71787203Retrovirus-Mediated Transduction of an Engineered Intron-Containing Purine Nucleoside Phosphorylase Gene
Q39214743Retrovirus-based mRNA transfer for transient cell manipulation
Q36221025Retrovirus-mediated expression of preprosomatostatin: posttranslational processing, intracellular storage, and secretion in GH3 pituitary cells
Q40396909Retrovirus-mediated gene transfer in cancer therapy
Q39696578Retrovirus-mediated gene transfer into hematopoietic stem cells.
Q41080907Retrovirus-mediated gene transfer into rat salivary gland cells in vitro and in vivo
Q41214784Retrovirus-mediated gene transfer into salivary glands in vivo
Q40671349Retrovirus-mediated gene transfer of human adenosine deaminase: expression of functional enzyme in murine hematopoietic stem cells in vivo
Q41545589Retrovirus-mediated gene transfer of transthyretin and transthyretin-methionine 30: a potential tool for the study of amyloidogenesis
Q45878998Retrovirus-mediated gene transfer targeted to malignant glioma cells in murine brain
Q34319023Retrovirus-mediated gene transfer to purified hemopoietic stem cells with long-term lympho-myelopoietic repopulating ability.
Q34983618Retrovirus-mediated insertion of expressed and non-expressed genes at identical chromosomal locations
Q33570031Retrovirus-mediated transduction of adult hepatocytes
Q45889908Retrovirus-mediated transfer and expression of drug resistance genes in human haematopoietic progenitor cells
Q36766745Retrovirus-mediated transfer and expression of the interleukin-3 gene in mouse hematopoietic cells result in a myeloproliferative disorder
Q35600024Retrovirus-mediated transfer of human adenosine deaminase gene sequences into cells in culture and into murine hematopoietic cells in vivo
Q41876682Retrovirus-mediated transgenic keratin expression in cultured fibroblasts: Specific domain functions in keratin stabilization and filament formation
Q40906270Retrovirus-mediated, stable scavenger-receptor gene transfer leads to functional endocytotic receptor expression, foam cell formation, and increased susceptibility to apoptosis in rabbit aortic smooth muscle cells
Q35034076Retroviruses as genetic tools to isolate transcriptionally active chromosomal regions
Q45866942RevM10-Mediated Inhibition of HIV-1 Replication in Chronically Infected T Cells
Q42617430Reverse transcription and packaging of hepatitis B virus (HBV)—RNA generates in vivo defective serum HBV particles
Q36900833Reverse transcription of 7S L RNA by an avian retrovirus
Q34354654Reversible binding of recombinant human immunodeficiency virus type 1 gag protein to nucleic acids in virus-like particle assembly in vitro
Q40971997Ribosomal frameshifting in yeast viruses.
Q36697793Role and specificity of T-cell subsets in spontaneous recovery from Friend virus-induced leukemia in mice
Q36796100Role of gag sequence in the biochemical properties and transforming activity of the avian sarcoma virus UR2-encoded gag-ros fusion protein
Q36818661Role of the PU.1 transcription factor in controlling differentiation of Friend erythroleukemia cells
Q69110537Role of the c-myc and the N-myc proto-oncogenes in the immortalization of neural precursors
Q40984080Role of the transmembrane sequence of spleen focus-forming virus gp55 in erythroleukemogenesis
Q36853856Roles of helper and defective retroviral genomes in murine erythroleukemia: studies of spleen focus-forming virus in the absence of helper
Q42816290Rous sarcoma virus encodes a transcriptional activator
Q34618023Rous sarcoma virus is integrated but not expressed in chicken early embryonic cells
Q45755448S- and G2-phase cell cycle arrests and apoptosis induced by ganciclovir in murine melanoma cells transduced with herpes simplex virus thymidine kinase.
Q42809173SV40 small t antigen enhances the transformation activity of limiting concentrations of SV40 large T antigen
Q33644899Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges
Q37219609Safety Issues Related to Retroviral-Mediated Gene Transfer in Humans
Q36090110Safety aspects of gene therapy
Q42467354Schwann cells infected with a recombinant retrovirus expressing myelin-associated glycoprotein antisense RNA do not form myelin
Q37527910Scientific and ethical considerations in human gene therapy
Q40139360Scrapie infection of prion protein-deficient cell line upon ectopic expression of mutant prion proteins
Q40038005Screening retroviral packaging cells for highly efficient virus production by using a combined selection procedure
Q37565230Secretion of human parathyroid hormone from rat pituitary cells infected with a recombinant retrovirus encoding preproparathyroid hormone
Q45888762Selection for phenylalanine hydroxylase activity in cells transformed with recombinant retroviruses
Q35857245Selective and nonselective packaging of cellular RNAs in retrovirus particles
Q42805402Selective expression of foreign genes in glioma cells: use of the mouse myelin basic protein gene promoter to direct toxic gene expression
Q21245112Selective gene silencing by viral delivery of short hairpin RNA
Q41287985Selective loss of H-2Ds antigen on a murine B lymphoma due to a post-transcriptional block in expression
Q35604467Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells
Q36785737Separation of simian virus 40 large-T-antigen-transforming and origin-binding functions from the ability to block differentiation
Q39581452Sequences in pol are required for transfer of human foamy virus-based vectors.
Q40132598Sequences responsible for erythroid and lymphoid leukemia in the long terminal repeats of Friend-mink cell focus-forming and Moloney murine leukemia viruses
Q36652108Sequences responsible for the distinctive hemolytic potentials of Friend and Moloney murine leukemia viruses are dispersed but confined to the psi-gag-PR region
Q38355080Sequences within both the 5′ untranslated region and the Gag gene are important for efficient encapsidation of Mason–Pfizer monkey virus RNA
Q45886049Severe combined immunodeficiencies and related disorders
Q42799992Shuttle vector system for the analysis of mutational events in mammalian chromosomal DNA.
Q40132184Significance of DNase I-hypersensitive sites in the long terminal repeats of a Moloney murine leukemia virus vector
Q36645412Simian immunodeficiency virus RNA is efficiently encapsidated by human immunodeficiency virus type 1 particles
Q40809732Simian retrovirus vectors for gene transfer in nonhuman primate cells
Q36690671Simian virus 40 large T-antigen expression decreases the G1 and increases the G2 + M cell cycle phase durations in exponentially growing cells
Q33812137Simian virus 40 small tumor antigen and an amino-terminal domain of large tumor antigen share a common transforming function
Q41655587Simple system for isolation of cellular and viral mutants for transformation by retrovirus
Q54593726Simplified plasmid rescue of host sequences adjacent to integrated proviruses.
Q42991441Sindbis virus: an efficient, broad host range vector for gene expression in animal cells
Q53538979Single-base mutations associated with mouse lymphomas.
Q33825579Single-step conversion of cells to retrovirus vector producers with herpes simplex virus-Epstein-Barr virus hybrid amplicons
Q68354939Site-specific gene expression in vivo by direct gene transfer into the arterial wall
Q30372344Site-specific mutagenesis identifies amino acid residues critical in prohormone processing.
Q37224218Somatic Gene Therapy
Q39752255Somatic gene therapy for human disease: background and prospects. Part I.
Q40922217Somatic gene therapy. Current status and future prospects
Q42796214Species specificity of interleukin 2 binding to individual receptor components
Q36655093Specific binding of human immunodeficiency virus type 1 gag polyprotein and nucleocapsid protein to viral RNAs detected by RNA mobility shift assays
Q59078565Specific growth response of ras-transformed embryo fibroblasts to tumour promoters
Q38288423Specific packaging of spliced retroviral vector transcripts lacking the Psi-region
Q42805869Specific viral oncogenes cause differential effects on cell-to-cell communication, relevant to the suppression of the transformed phenotype by normal cells
Q36699497Specificity of Rous sarcoma virus nucleocapsid protein in genomic RNA packaging
Q36687788Specificity of retroviral RNA packaging
Q36797695Spleen necrosis virus, an avian retrovirus, can infect primate cells
Q45522377Spleen necrosis virus-based vector delivery of anti-HIV-1 genes potently protects human hematopoietic cells from HIV-1 infection
Q72720016Spontaneous dimerization of retroviral MoMuLV RNA
Q43842361Stability of retrovirally transduced markers in a rat cell line
Q35134462Stable alphavirus packaging cell lines for Sindbis virus and Semliki Forest virus-derived vectors
Q41577351Stable expression of antibiotic resistance genes using a promoter fragment of the U1 snRNA gene
Q41523293Stable expression of the wild-type p53 gene in human lung cancer cells after retrovirus-mediated gene transfer
Q41285166Stable overexpression of human HSF-1 in murine cells suggests activation rather than expression of HSF-1 to be the key regulatory step in the heat shock gene expression
Q64379700Stable transfer of a mouse dihydrofolate reductase gene into a deficient cell line using human adenovirus vector
Q40649557Stably transmitted triple-promoter retroviral vectors and their use in transformation of primary mammalian cells
Q35832690Stem cell factor binding to retrovirus primer binding site silencers
Q42825002Streptavidin-based quantitative staining of intracellular antigens for flow cytometric analysis
Q42813481Stromal cell-dependent growth of leukemic cells from murine erythroblastic leukemia
Q39553977Structural and functional studies of protein kinase C.
Q28285434Structural basis for packaging the dimeric genome of Moloney murine leukaemia virus
Q27656384Structural characterization of a 39-residue synthetic peptide containing the two zinc binding domains from the HIV-1 p7 nucleocapsid protein by CD and NMR spectroscopy
Q37974642Structural dynamics of retroviral genome and the packaging
Q35832727Structural interactions between retroviral Gag proteins examined by cysteine cross-linking
Q34185507Structure and expression of HLA-DQ alpha and -DX alpha genes: interallelic alternate splicing of the HLA-DQ alpha gene and functional splicing of the HLA-DQ alpha gene using a retroviral vector
Q36864676Structure and transforming function of transduced mutant alleles of the chicken c-myc gene
Q27664955Structure of a Conserved Retroviral RNA Packaging Element by NMR Spectroscopy and Cryo-Electron Tomography
Q42818953Studies on compartmentation and turnover of murine retrovirus envelope proteins
Q35765188Studies on the pathology, especially brain lesions, induced by R7, a spontaneous mutant of Moloney murine sarcoma virus 124.
Q33818725Suicide genes: past, present and future perspectives
Q40935159Suppression of TGF-beta1 in human gliomas by retroviral gene transfection enhances susceptibility to LAK cells
Q40928382Suppression of anchorage-independent growth of human cancer cell lines by the drs gene
Q34597099Suppression of endo B cytokeratin by its antisense RNA inhibits the normal coexpression of endo A cytokeratin
Q34340811Suppression of heat-induced hsp70 expression by the 70-kDa subunit of the human Ku autoantigen
Q41407134Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells
Q32099220Suppression of v-src transformation by the drs gene
Q36485425Supramolecular organization of immature and mature murine leukemia virus revealed by electron cryo-microscopy: implications for retroviral assembly mechanisms
Q69737071Surface expression of the T cell receptor complex requires charged residues within the alpha chain transmembrane region
Q41686665Survival and differentiation within the adult mouse striatum of grafted rat pheochromocytoma cells (PC12) genetically modified to express recombinant beta-NGF.
Q41662310Survival period of tumor-bearing mice is prolonged after the interferon-gamma-producing gene transfer
Q33932705Susceptibility of inbred strains of mice to murine AIDS (MAIDS) correlates with target cell expansion and high expression of defective MAIDS virus
Q45866838T lymphocyte-directed gene therapy for ADA- SCID: initial trial results after 4 years.
Q43976877TGF alpha stimulates growth of skin papillomas by autocrine and paracrine mechanisms but does not cause neoplastic progression
Q24594918Targeted disruption of the c-fos gene demonstrates c-fos-dependent and -independent pathways for gene expression stimulated by growth factors or oncogenes
Q48792700Targeted killing of migrating glioma cells by injection of HTK-modified glioma cells
Q45069562Targeting and processing of pro-opiomelanocortin in neuronal cell lines
Q34365155Targeting of retroviral vectors for gene therapy
Q36232783Targeting of the "insulin-responsive" glucose transporter (GLUT4) to the regulated secretory pathway in PC12 cells
Q38326676Targeting retroviral vectors to CD34-expressing cells: binding to CD34 does not catalyze virus-cell fusion
Q30466758Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA.
Q28592095Tetracysteine-tagged prion protein allows discrimination between the native and converted forms
Q36768150The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc
Q42807418The CML-specific P210 bcr/abl protein, unlike v-abl, does not transform NIH/3T3 fibroblasts
Q36700906The Ets-related transcription factor PU.1 immortalizes erythroblasts
Q36564631The Myc negative autoregulation mechanism requires Myc-Max association and involves the c-myc P2 minimal promoter
Q29618472The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
Q40041446The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest.
Q41534206The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells
Q36732985The amino-terminal 14 amino acids of v-src can functionally replace the extracellular and transmembrane domains of v-erbB
Q41693495The amino-terminal 147 amino acids of SV40 large T antigen transform secondary rat embryo fibroblasts
Q24654115The amino-terminal domain of the v-fms oncogene product includes a functional signal peptide that directs synthesis of a transforming glycoprotein in the absence of feline leukemia virus gag sequences
Q39406282The antibody sc-33040-R fails to specifically recognize phosphorylation of ErbB4 on tyrosine1056
Q37350126The application of viral vectors to enhance regeneration after peripheral nerve repair.
Q33783331The bovine leukemia virus encapsidation signal is composed of RNA secondary structures.
Q28301200The bovine leukemia virus encapsidation signal is discontinuous and extends into the 5' end of the gag gene
Q33929830The bovine leukemia virus p34 is a transactivator protein
Q36787130The carboxy terminus of pp60c-src is a regulatory domain and is involved in complex formation with the middle-T antigen of polyomavirus
Q34591671The cellular protein La functions in enhancement of virus release through lipid rafts facilitated by murine leukemia virus glycosylated Gag.
Q39881014The critical N-linked glycan of murine leukemia virus envelope protein promotes both folding of the C-terminal domains of the precursor polyprotein and stability of the postcleavage envelope complex
Q31014896The cultural mouse
Q36332163The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction
Q41523285The development and testing of retroviral vectors expressing trans-dominant mutants of HIV-1 proteins to confer anti-HIV-1 resistance
Q37535778The development of gene therapy: from monogenic recessive disorders to complex diseases such as cancer.
Q35832442The dimerization/packaging sequence is dispensable for both the formation of high-molecular-weight RNA complexes within retroviral particles and the synthesis of proviruses of normal structure.
Q41716342The electrogenic sodium bicarbonate cotransporter: developmental expression in rat brain and possible role in acid vulnerability.
Q24675131The envelope glycoprotein of an amphotropic murine retrovirus binds specifically to the cellular receptor/phosphate transporter of susceptible species
Q28513922The epidermal growth factor receptor couples transforming growth factor-alpha, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4
Q45837892The gag and pol genes of bovine leukemia virus: nucleotide sequence and analysis
Q40077796The genetics of murine leukemia viruses.
Q41617860The hepatocyte-specific phenotype of murine liver cells correlates with high expression of connexin32 and connexin26 but very low expression of connexin43
Q24682817The human immunodeficiency virus type 1 encapsidation site is a multipartite RNA element composed of functional hairpin structures
Q34434755The human immunodeficiency virus type 1 packaging signal and major splice donor region have a conserved stable secondary structure
Q33929960The in vitro behavior of hemopoietic cells transformed by polyoma middle T antigen parallels that of primary human myeloid leukemic cells
Q34633466The inside out of lentiviral vectors
Q36828053The majority of cells infected with the defective murine AIDS virus belong to the B-cell lineage
Q35034033The malignant conversion step of mouse skin carcinogenesis
Q36918582The membrane glycoprotein of Friend spleen focus-forming virus: evidence that the cell surface component is required for pathogenesis and that it binds to a receptor.
Q28291337The metanephric blastema differentiates into collecting system and nephron epithelia in vitro
Q34258836The molecular genetics of human hemoglobin
Q45804450The nucleotide sequence of the Akv murine leukemia virus genome
Q35866801The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses
Q36828275The palindromic LTR-LTR junction of Moloney murine leukemia virus is not an efficient substrate for proviral integration.
Q41760092The primary structure of major viral RNA in a rat cell line transfected with type 47 human papillomavirus DNA and the transforming activity of its cDNA and E6 gene
Q36220522The propeptide of preprosomatostatin mediates intracellular transport and secretion of alpha-globin from mammalian cells
Q33919776The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix
Q33846535The ras and myc oncogenes cooperate in tumor induction in many tissues when introduced into midgestation mouse embryos by retroviral vectors
Q28569479The rat interleukin-5 gene: Characterization and expression by retroviral gene transfer and polymerase chain reaction
Q36687255The requirements for viral entry differ from those for virally induced syncytium formation in NIH 3T3/DTras cells exposed to Moloney murine leukemia virus
Q38185388The role of growth factors in normal and neoplastic haemopoiesis
Q36906696The role of the membrane-spanning domain sequence in glycoprotein-mediated membrane fusion
Q42819692The thymidine kinase/ganciclovir-mediated "suicide" effect is variable in different tumor cells
Q34050744The truncation that generated the v-cbl oncogene reveals an ability for nuclear transport, DNA binding and acute transformation
Q33836887The two subunits of the human asialoglycoprotein receptor have different fates when expressed alone in fibroblasts
Q67282722The use of a retroviral vector to identify foetal striatal neurones transplanted into the adult striatum
Q41661372The use of genetically altered astrocytes to provide nerve growth factor to adrenal chromaffin cells grafted into the striatum
Q44018943The v-fms oncogene induces factor independence and tumorigenicity in CSF-1 dependent macrophage cell line
Q36839863The v-fms oncogene induces factor-independent growth and transformation of the interleukin-3-dependent myeloid cell line FDC-P1.
Q53511722The v-ras oncogene inhibits the expression of differentiation markers and facilitates expression of cytokeratins 8 and 18 in mouse keratinocytes
Q45882944The vascular endothelial cell as a vehicle for gene therapy
Q48587406Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells
Q70338863Tissue-specific expression of functionally rearranged lambda 1 Ig gene through a retrovirus vector
Q41428152Tissue-specific targeting of retroviral vectors through ligand-receptor interactions
Q73850541To fuse or not to fuse: the effects of electrostatic interactions, hydrophobic forces, and structural amphiphilicity on protein-mediated membrane destabilization
Q70472317Toxicity studies of retroviral-mediated gene transfer for the treatment of brain tumors
Q34450066Transcriptional Silencing of Retroviral Vectors.
Q36795776Transduction of cellular neo mRNA by retrovirus-mediated recombination
Q33929116Transduction of host cellular sequences by a retroviral shuttle vector
Q36761058Transduction of human colony-stimulating factor-1 (CSF-1) receptor into interleukin-3-dependent mouse myeloid cells induces both CSF-1-dependent and factor-independent growth
Q43898723Transfection of a DNA/protein complex into nuclei of mammalian cells using polyoma capsids and electroporation
Q37249173Transfer and expression of the human multiple drug resistance gene into live mice
Q40344036Transfer of 15-lipoxygenase gene into rabbit iliac arteries results in the appearance of oxidation-specific lipid-protein adducts characteristic of oxidized low density lipoprotein
Q45149175Transfer of functional EGF receptors to an IL3-dependent cell line
Q41384774Transfer of genes into embryonal carcinoma cells by retrovirus infection: efficient expression from an internal promoter
Q37672708Transfer of genes into hematopoietic cells using recombinant DNA viruses
Q24683087Transfer of single gene-containing long terminal repeats into the genome of mammalian cells by a retroviral vector carrying the cre gene and the loxP site
Q41462810Transformation by myc prevents fusion but not biochemical differentiation of C2C12 myoblasts: mechanisms of phenotypic correction in mixed culture with normal cells.
Q42806558Transformation by oncogenes encoding protein kinases induces the metastatic phenotype
Q53551047Transformation mediated by the SV40 T antigens: separation of the overlapping SV40 early genes with a retroviral vector.
Q38344538Transformation of NIH 3T3 fibroblasts by an activated form of p59hck
Q41687212Transformation of a mammary epithelial cell line by the v-raf and v-mos oncogenes
Q33682660Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein
Q41760172Transformation of murine melanocytes by basic fibroblast growth factor cDNA and oncogenes and selective suppression of the transformed phenotype in a reconstituted cutaneous environment
Q39511011Transforming genes and target cells of murine spleen focus-forming viruses
Q45864350Transgene expression and RNA interference in embryonic stem cells
Q48910622Transgene expression in zebrafish: A comparison of retroviral-vector and DNA-injection approaches
Q37409515Transgenesis by means of blastocyst-derived embryonic stem cell lines
Q74440357Transgenic Technology and Laboratory Animal Science
Q69352129Transgenic animals
Q70168226Transgenic chickens: insertion of retroviral genes into the chicken germ line
Q36739755Translational considerations for CNS gene therapy
Q71624177Transplantation of retroviral producer cells for in vivo gene transfer into mouse skeletal muscle
Q40781409Transplants of cells genetically modified to express neurotrophin-3 rescue axotomized Clarke's nucleus neurons after spinal cord hemisection in adult rats
Q40952232Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function.
Q36793262Transport and assembly of gag proteins into Moloney murine leukemia virus
Q35573405Treatment of autoimmune disease by adoptive cellular gene therapy
Q41657338Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4.
Q92457503Truncated oncoproteins of retroviruses and hepatitis B virus: A lesson in contrasts
Q36230110Tumor suppression after tumor cell-targeted tumor necrosis factor alpha gene transfer
Q35984403Tumour suppression associated with expression of human insulin-like growth factor II.
Q69636010Turnover and compartmentation of gp70/p15 E in psi 2 cells
Q36918548Two distinct sequence elements mediate retroviral gene expression in embryonal carcinoma cells
Q33662050Two dominant-acting selectable markers for gene transfer studies in mammalian cells
Q37674587Two oncogenes, v-fos and v-ras, cooperate to convert normal keratinocytes to squamous cell carcinoma
Q46849388Two pairs of recombination signals are sufficient to cause immunoglobulin V-(D)-J joining
Q41744094Two subfamilies of murine retrotransposon ETn sequences
Q41484320Two-dimensional gel mapping of small GTPases reveals transformation-specific changes during oncogenesis
Q44049774Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src
Q36687162U3 long terminal repeat-mediated induction of intracellular immunity by a murine retrovirus: a novel model of latency for retroviruses
Q27313711UNC93B1 mediates host resistance to infection with Toxoplasma gondii
Q36905035Unusual features of the leader sequence of Rous sarcoma virus packaging mutant TK15
Q48313396Unusual immunoglobulin gene rearrangement leads to replacement of recombinational signal sequences
Q60160340Use of Retroviral Vectors for Gene Transfer and Expression
Q33880924Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos
Q29620166Use of eukaryotic expression technology in the functional analysis of cloned genes
Q41586156Use of multidrug resistance gene in mammalian expression vectors
Q36869583Use of recombinant retroviruses to study the regulation of integrated adenovirus early promoters
Q41582824Use of retroviral vectors for gene transfer and expression
Q42643989V(D)J recombination of chromosomally integrated, wild-type deletional and inversional substrates occur at similar frequencies with no preference for orientation
Q36901149Varying the position of a retrovirus packaging sequence results in the encapsidation of both unspliced and spliced RNAs
Q41430840Vinculin-deficient PC12 cell lines extend unstable lamellipodia and filopodia and have a reduced rate of neurite outgrowth
Q40504840Viral RNA annealing activities of the nucleocapsid protein of Moloney murine leukemia virus are zinc independent
Q38661287Viral Vectors for Gene Therapy: Translational and Clinical Outlook
Q36821051Viral and cellular factors governing hamster cell infection by murine and gibbon ape leukemia viruses
Q89656152Viral approaches to study the mammalian brain: Lineage tracing, circuit dissection and therapeutic applications
Q35210466Viral therapy for glioblastoma
Q34836871Virus-based gene delivery systems
Q37825015Viruses as vectors
Q33277347Widespread Dispersion of Neuronal Clones Across Functional Regions of the Cerebral Cortex
Q62397562[72] Identification of regulatory elements of cloned genes with functional assays
Q24319116bcl-2 gene enables rescue from in vitro myelosuppression (bone marrow cell death) induced by chemotherapy
Q33919315bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.
Q33958488c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points
Q40107854cis elements and trans-acting factors involved in dimer formation of murine leukemia virus RNA.
Q36910202cis-Acting RNA packaging locus in the 115-nucleotide direct repeat of Rous sarcoma virus
Q34338573cis-Acting elements important for retroviral RNA packaging specificity
Q33783544cis-Acting sequences required for simian foamy virus type 1 vectors
Q36695651cis-acting sequences required for encapsidation of duck hepatitis B virus pregenomic RNA.
Q35865815cis-active structural motifs involved in specific encapsidation of Moloney murine leukemia virus RNA.
Q40847872p21(WAF1/Cip1) retards the growth of human squamous cell carcinomas in vivo
Q40409057p21X mRNA is expressed as a singly spliced pX transcript from defective provirus genomes having a partial deletion of the pol-env region in human T-cell leukemia virus type 1-infected cells
Q41502371p53Val135 temperature sensitive mutant suppresses growth of human breast cancer cells
Q43647683pp60(c-src) modulates microvascular endothelial phenotype and in vitro angiogenesis
Q71974461pp60c-src is required for the induction of a quiescent mesangial cell phenotype
Q36759826pp60c-src variants containing lesions that affect phosphorylation at tyrosines 416 and 527.
Q36530992pp60src tyrosine kinase modulates P19 embryonal carcinoma cell fate by inhibiting neuronal but not epithelial differentiation
Q36791062ras effector loop mutations that dissociate p120GAP and neurofibromin interactions
Q39873362trans-acting proteins involved in RNA encapsidation and viral assembly in human immunodeficiency virus type 1.

Q54948492Psi-2described by sourceP1343

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