scholarly article | Q13442814 |
P819 | ADS bibcode | 2015PLoSO..1033699H |
P356 | DOI | 10.1371/JOURNAL.PONE.0133699 |
P932 | PMC publication ID | 4526660 |
P698 | PubMed publication ID | 26244501 |
P5875 | ResearchGate publication ID | 280869231 |
P50 | author | Hung-Chuan Chiu | Q59686909 |
P2093 | author name string | Tsai-Ling Liao | |
Hung-Jen Liu | |||
Kuo-Pin Chuang | |||
Wei-Ru Huang | |||
Wing-Ling Shih | |||
P2860 | cites work | AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1 | Q22254000 |
The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation | Q24290417 | ||
Tpr is localized within the nuclear basket of the pore complex and has a role in nuclear protein export | Q24292285 | ||
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN | Q24292919 | ||
Ubiquitination regulates PTEN nuclear import and tumor suppression | Q24292946 | ||
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex | Q24295120 | ||
Nucleoporins as components of the nuclear pore complex core structure and Tpr as the architectural element of the nuclear basket | Q24298298 | ||
Nucleoporin translocated promoter region (Tpr) associates with dynein complex, preventing chromosome lagging formation during mitosis. | Q24298502 | ||
Rak functions as a tumor suppressor by regulating PTEN protein stability and function | Q24312999 | ||
The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2 | Q24561705 | ||
The first 30 years of p53: growing ever more complex | Q24645732 | ||
A jumbo problem: mapping the structure and functions of the nuclear pore complex | Q27013694 | ||
Activation of the N-Ras-PI3K-Akt-mTOR pathway by hepatitis C virus: control of cell survival and viral replication | Q27470019 | ||
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B | Q27860731 | ||
TOR signaling in growth and metabolism | Q27860757 | ||
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling | Q28131740 | ||
Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin | Q28217173 | ||
Defining the role of mTOR in cancer | Q28235431 | ||
Retardation of cell growth by avian reovirus p17 through the activation of p53 pathway | Q28270765 | ||
Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization | Q28290083 | ||
Enhanced phosphorylation of p53 by ATM in response to DNA damage | Q28609838 | ||
Regulation of PTEN transcription by p53 | Q28646911 | ||
Proteasome inhibition reduces avian reovirus replication and apoptosis induction in cultured cells | Q39985514 | ||
Infectious tenosynovitis (viral arthritis): influence of maternal antibodies on the development of tenosynovitis lesions after experimental infection by day-old chickens with tenosynovitis virus | Q40025149 | ||
Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38. | Q40054340 | ||
Regulation of cyclin D1 expression by mTORC1 signaling requires eukaryotic initiation factor 4E-binding protein 1. | Q40088642 | ||
A new class of fusion-associated small transmembrane (FAST) proteins encoded by the non-enveloped fusogenic reoviruses | Q40387199 | ||
Avian reovirus sigmaC protein induces apoptosis in cultured cells | Q40576362 | ||
Regulation of cell migration by the C2 domain of the tumor suppressor PTEN. | Q40587498 | ||
The K1 protein of Kaposi's sarcoma-associated herpesvirus activates the Akt signaling pathway | Q40594961 | ||
Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma | Q40702649 | ||
ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation | Q40747424 | ||
The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade | Q40816601 | ||
The second open reading frame of the avian reovirus S1 gene encodes a transcription-dependent and CRM1-independent nucleocytoplasmic shuttling protein. | Q40976700 | ||
Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells | Q41407134 | ||
Therapeutic potential of mitotic interaction between the nucleoporin Tpr and aurora kinase A. | Q42046251 | ||
AMP-activated protein kinase facilitates avian reovirus to induce mitogen-activated protein kinase (MAPK) p38 and MAPK kinase 3/6 signalling that is beneficial for virus replication | Q43298123 | ||
The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling | Q43848062 | ||
Identification and Serological Differentiation of Several Reovirus Strains Isolated from Chickens with Suspected Malabsorption Syndrome | Q45118134 | ||
Avian reovirus influences phosphorylation of several factors involved in host protein translation including eukaryotic translation elongation factor 2 (eEF2) in Vero cells. | Q46030357 | ||
Modification of late membrane permeability in avian reovirus-infected cells: viroporin activity of the S1-encoded nonstructural p10 protein. | Q50584889 | ||
One-thousand-and-one substrates of protein kinase CK2? | Q29615345 | ||
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway | Q29616144 | ||
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression | Q29617473 | ||
Nucleotide sequence analysis of human tpr cDNA clones | Q31121814 | ||
PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model | Q32069431 | ||
Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells | Q32084034 | ||
ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability | Q33706377 | ||
How do small GTPase signal transduction pathways regulate cell cycle entry? | Q33796334 | ||
Rb function in cell-cycle regulation and apoptosis | Q33900128 | ||
Silencing nuclear pore protein Tpr elicits a senescent-like phenotype in cancer cells | Q33979961 | ||
Paradoxical suppression of cellular senescence by p53 | Q34006762 | ||
Human cytomegalovirus major immediate-early proteins and simian virus 40 large T antigen can inhibit apoptosis through activation of the phosphatidylinositide 3'-OH kinase pathway and the cellular kinase Akt. | Q34336521 | ||
Sequential partially overlapping gene arrangement in the tricistronic S1 genome segments of avian reovirus and Nelson Bay reovirus: implications for translation initiation | Q34357784 | ||
The p17 nonstructural protein of avian reovirus triggers autophagy enhancing virus replication via activation of phosphatase and tensin deleted on chromosome 10 (PTEN) and AMP-activated protein kinase (AMPK), as well as dsRNA-dependent protein kinas | Q34509319 | ||
Tricine-SDS-PAGE. | Q34615345 | ||
Awakening guardian angels: drugging the p53 pathway | Q35014385 | ||
Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways | Q36384266 | ||
Regulation of autophagy by nucleoporin Tpr. | Q36410559 | ||
Transcriptional regulation by p53: one protein, many possibilities | Q36436698 | ||
Dynamic nuclear pore complexes: life on the edge. | Q36508009 | ||
From Tpr-Met to Met, tumorigenesis and tubes. | Q36745364 | ||
The nuclear affairs of PTEN. | Q37063858 | ||
Nucleocytoplasmic transport of proteins | Q37087415 | ||
Understanding PTEN regulation: PIP2, polarity and protein stability | Q37270444 | ||
Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages | Q37280434 | ||
PI3K-Akt signaling and viral infection | Q37355200 | ||
Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis | Q37411011 | ||
Divergent roles of autophagy in virus infection | Q37679218 | ||
Evidence for the multimeric nature and cell binding ability of avian reovirus sigma 3 protein | Q38357153 | ||
The RhoA-ROCK-PTEN pathway as a molecular switch for anchorage dependent cell behavior | Q39412541 | ||
Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells | Q39460733 | ||
Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model | Q39542680 | ||
Pharmacologic inhibition of MEK and PI-3K converges on the mTOR/S6 pathway to decelerate cellular senescence | Q39845659 | ||
A role for autophagolysosomes in dengue virus 3 production in HepG2 cells | Q39876782 | ||
Growth stimulation leads to cellular senescence when the cell cycle is blocked | Q39925937 | ||
p21(Waf1/Cip1/Sdi1) mediates retinoblastoma protein degradation. | Q53554846 | ||
Differential regulation of Akt/protein kinase B isoforms during cell cycle progression | Q60155825 | ||
PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway | Q74404969 | ||
Activation of small GTPases RhoA and Rac1 is required for avian reovirus p10-induced syncytium formation | Q81606835 | ||
Modulation of p53 by mitogen-activated protein kinase pathways and protein kinase C delta during avian reovirus S1133-induced apoptosis | Q83235743 | ||
Avian reovirus S1133-induced DNA damage signaling and subsequent apoptosis in cultured cells and in chickens | Q84584250 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Reovirus | Q69812835 |
P304 | page(s) | e0133699 | |
P577 | publication date | 2015-08-05 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways | |
P478 | volume | 10 |
Q26700049 | Adapting the Stress Response: Viral Subversion of the mTOR Signaling Pathway |
Q55365673 | Autophagy Benefits the Replication of Egg Drop Syndrome Virus in Duck Embryo Fibroblasts. |
Q91987898 | Autophagy induction by the pathogen receptor NECTIN4 and sustained autophagy contribute to peste des petits ruminants virus infectivity |
Q33899583 | Avian reovirus p17 and σA act cooperatively to downregulate Akt by suppressing mTORC2 and CDK2/cyclin A2 and upregulating proteasome PSMB6. |
Q91697506 | Cdc20 and molecular chaperone CCT2 and CCT5 are required for the Muscovy duck reovirus p10.8-induced cell cycle arrest and apoptosis |
Q41348469 | Classical swine fever virus Shimen infection increases p53 signaling to promote cell cycle arrest in porcine alveolar macrophages |
Q43237479 | Correction: Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways |
Q36686335 | Dissection and integration of the autophagy signaling network initiated by bluetongue virus infection: crucial candidates ERK1/2, Akt and AMPK. |
Q52649595 | EGCG inhibited bladder cancer T24 and 5637 cell proliferation and migration via PI3K/AKT pathway. |
Q26771799 | Exploring Reovirus Plasticity for Improving Its Use as Oncolytic Virus |
Q59353075 | Genomic sequence and phylogenetic analyses of two novel orthoreovirus strains isolated from Pekin ducks in 2014 in Germany |
Q92376498 | Heterogeneous Nuclear Ribonucleoprotein A1 and Lamin A/C Modulate Nucleocytoplasmic Shuttling of Avian Reovirus p17 |
Q59358650 | Mechanistic insights into avian reovirus p17-modulated suppression of cell cycle CDK-cyclin complexes and enhancement of p53 and cyclin H interaction |
Q37698001 | Muscovy duck reovirus σNS protein triggers autophagy enhancing virus replication |
Q58745484 | Newcastle Disease Virus V Protein Promotes Viral Replication in HeLa Cells through the Activation of MEK/ERK Signaling |
Q50053840 | Piperlongumine induces apoptosis and autophagy in leukemic cells through targeting the PI3K/Akt/mTOR and p38 signaling pathways |
Q28388816 | Suppression of Vimentin Phosphorylation by the Avian Reovirus p17 through Inhibition of CDK1 and Plk1 Impacting the G2/M Phase of the Cell Cycle |
Q56988192 | The Interplay of Viral and Host Factors in Chikungunya Virus Infection: Targets for Antiviral Strategies |
Q55032443 | The cyclohexene derivative MC-3129 exhibits antileukemic activity via RhoA/ROCK1/PTEN/PI3K/Akt pathway-mediated mitochondrial translocation of cofilin. |
Q92987978 | The multifarious roles of heterogeneous ribonucleoprotein A1 in viral infections |
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