| scholarly article | Q13442814 |
| P2093 | author name string | J L Brown | |
| C Eng | |||
| L P Weng | |||
| P433 | issue | 6 | |
| P921 | main subject | breast cancer | Q128581 |
| P304 | page(s) | 599-604 | |
| P577 | publication date | 2001-03-01 | |
| P1433 | published in | Human Molecular Genetics | Q2720965 |
| P1476 | title | PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model | |
| P478 | volume | 10 |
| Q35869429 | A 39-bp deletion polymorphism in PTEN in African American individuals: implications for molecular diagnostic testing |
| Q34114284 | A Pleiotrophin C-terminus peptide induces anti-cancer effects through RPTPβ/ζ |
| Q24606333 | A clinical scoring system for selection of patients for PTEN mutation testing is proposed on the basis of a prospective study of 3042 probands |
| Q28595077 | Ablation of dihydroceramide desaturase confers resistance to etoposide-induced apoptosis in vitro |
| Q45869247 | Adenovirus-mediated transfer of the PTEN gene inhibits human colorectal cancer growth in vitro and in vivo |
| Q36973814 | Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy |
| Q36815312 | Altered PTEN, ATRX, CHGA, CHGB, and TP53 expression are associated with aggressive VHL-associated pancreatic neuroendocrine tumors |
| Q37431681 | Analysis of PTEN complex assembly and identification of heterogeneous nuclear ribonucleoprotein C as a component of the PTEN-associated complex |
| Q53474990 | Association of CCND1 overexpression with KRAS and PTEN alterations in specific subtypes of non-small cell lung carcinoma and its influence on patients' outcome. |
| Q35078446 | Autophagy: a barrier or an adaptive response to cancer. |
| Q35921644 | Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways |
| Q33899583 | Avian reovirus p17 and σA act cooperatively to downregulate Akt by suppressing mTORC2 and CDK2/cyclin A2 and upregulating proteasome PSMB6. |
| Q91011180 | B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells |
| Q44350476 | BMP2 exposure results in decreased PTEN protein degradation and increased PTEN levels |
| Q24305156 | Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases |
| Q39890810 | Biphasic estradiol-induced AKT phosphorylation is modulated by PTEN via MAP kinase in HepG2 cells |
| Q38705934 | CDK4 protein is degraded by anaphase-promoting complex/cyclosome in mitosis and reaccumulates in early G1 phase to initiate a new cell cycle in HeLa cells |
| Q28278854 | Cancer phenomics: RET and PTEN as illustrative models |
| Q33626022 | Causal reasoning identifies mechanisms of sensitivity for a novel AKT kinase inhibitor, GSK690693. |
| Q39365401 | Cell Cycle Control by PTEN. |
| Q39588832 | Chemostat-based transcriptional analysis of growth rate change and BCL-2 over-expression in NS0 cells |
| Q26798258 | Circadian disruption and breast cancer: an epigenetic link? |
| Q36313163 | Class reunion: PTEN joins the nuclear crew. |
| Q49818398 | Clinical implications of PTEN loss in prostate cancer |
| Q34141574 | Concomitant depletion of PTEN and p27 and overexpression of cyclin D1 may predict a worse prognosis for patients with post-operative stage II and III colorectal cancer |
| Q42066649 | Conditional deletion of Pten causes bronchiolar hyperplasia |
| Q36525146 | Cordyceps militaris and mycelial fermentation induced apoptosis and autophagy of human glioblastoma cells |
| Q81811800 | Correlation between loss of PTEN expression and PKB/AKT phosphorylation in hepatocellular carcinoma |
| Q37452346 | Deletion of Pten in the mouse enteric nervous system induces ganglioneuromatosis and mimics intestinal pseudoobstruction |
| Q24803723 | Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancer |
| Q28297001 | Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse |
| Q29568322 | Dual neuroprotective signaling mediated by downregulating two distinct phosphatase activities of PTEN. |
| Q41170725 | Dysregulation of PTEN in cardiopulmonary vascular remodeling induced by pulmonary hypertension. |
| Q39658846 | ESM-1 silencing decreased cell survival, migration, and invasion and modulated cell cycle progression in hepatocellular carcinoma |
| Q34583094 | Effects and mechanisms of silibinin on human hepatoma cell lines |
| Q38505848 | Effects of flavonoids genistein and biochanin a on gene expression and their metabolism in human mammary cells |
| Q43564152 | Epithelial Pten controls acute lung injury and fibrosis by regulating alveolar epithelial cell integrity. |
| Q37416668 | Exome sequencing reveals germline gain-of-function EGFR mutation in an adult with Lhermitte-Duclos disease. |
| Q21136078 | Expression of versican 3'-untranslated region modulates endogenous microRNA functions |
| Q40757135 | Functional roles of Akt signaling in mouse skin tumorigenesis. |
| Q35974781 | Gene expression in breastmilk cells is associated with maternal and infant characteristics. |
| Q37955107 | Genetic alterations of PTEN in human melanoma |
| Q37270416 | Genetic and phenotypic heterogeneity in the PTEN hamartoma tumour syndrome. |
| Q37305035 | Genetic modelling of the PTEN/AKT pathway in cancer research |
| Q33905657 | Germline Inactivation of PTEN and Dysregulation of the Phosphoinositol-3-Kinase/Akt Pathway Cause Human Lhermitte-Duclos Disease in Adults |
| Q28384465 | HCV infection-associated hepatocellular carcinoma in humanized mice |
| Q53118756 | Hematopoietic Stem Cell Activity Is Regulated by Pten Phosphorylation Through a Niche-Dependent Mechanism. |
| Q34073864 | Identification of myelin transcription factor 1 (MyT1) as a subunit of the neural cell type-specific lysine-specific demethylase 1 (LSD1) complex. |
| Q50752792 | Inactivation of PTEN is associated with a low p27Kip1 protein expression in breast carcinoma. |
| Q24548285 | Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest |
| Q37351516 | Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cells |
| Q38217855 | Link between PI3K/AKT/PTEN Pathway and NOX Proteinin Diseases |
| Q24797910 | Loss of cellular adhesion to matrix induces p53-independent expression of PTEN tumor suppressor |
| Q36277846 | Mannan-modified Ad5-PTEN treatment combined with docetaxel improves the therapeutic effect in H22 tumor-bearing mice |
| Q33719554 | MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling |
| Q40134855 | Models representing type I and type II human endometrial cancers: Ishikawa H and Hec50co cells. |
| Q47802550 | Molecular alterations associated with cyclin D1 overexpression in endometrial cancer |
| Q34554750 | Multiparameter analyses of cell cycle regulatory proteins in human breast cancer: a key to definition of separate pathways in tumorigenesis |
| Q39626053 | Mutational Analysis of the PTEN Gene and Its Effects in Esophageal Squamous Cell Carcinoma |
| Q94521960 | Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity |
| Q38895958 | Ndfip1 represses cell proliferation by controlling Pten localization and signaling specificity |
| Q39103988 | Neferine, an alkaloid from lotus seed embryo, inhibits human lung cancer cell growth by MAPK activation and cell cycle arrest. |
| Q55054900 | Next Generation Sequencing of urine exfoliated cells: an approach of prostate cancer microRNAs research. |
| Q57590602 | Non-canonical role of cancer-associated mutant SEC23B in the ribosome biogenesis pathway |
| Q57591227 | Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma |
| Q28564702 | Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs |
| Q28587617 | Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1 |
| Q28504804 | Nuclear receptor TLX regulates cell cycle progression in neural stem cells of the developing brain |
| Q61796084 | Oncogenic Y68 frame shift mutation of PTEN represents a mechanism of docetaxel resistance in endometrial cancer cell lines |
| Q58134027 | Over-expression of PTEN on proliferation and apoptosis in canine mammary tumors cells |
| Q37563404 | PIASxα ligase enhances SUMO1 modification of PTEN protein as a SUMO E3 ligase |
| Q36268735 | PTEN and Akt expression during growth of human ovarian follicles |
| Q46452179 | PTEN expression in ovine granulosa cells increases during terminal follicular growth |
| Q44702044 | PTEN immunohistochemical expression is suppressed in G1 endometrioid adenocarcinoma of the uterine corpus |
| Q37139779 | PTEN in brain tumors |
| Q42412809 | PTEN in liver diseases and cancer |
| Q35661819 | PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1. |
| Q44737517 | PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells |
| Q37856722 | PTEN loss in the continuum of common cancers, rare syndromes and mouse models. |
| Q40250832 | PTEN modulates hepatitis B virus-X protein induced survival signaling in Chang liver cells |
| Q40639993 | PTEN modulates insulin-like growth factor II (IGF-II)-mediated signaling; the protein phosphatase activity of PTEN downregulates IGF-II expression in hepatoma cells |
| Q37092758 | PTEN mutation, methylation and expression in breast cancer patients |
| Q35747653 | PTEN mutational spectra, expression levels, and subcellular localization in microsatellite stable and unstable colorectal cancers |
| Q28482319 | PTEN negatively regulates MAPK signaling during Caenorhabditis elegans vulval development |
| Q28505099 | PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression |
| Q34796595 | PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium |
| Q27011088 | PTEN regulation of ERK1/2 signaling in cancer |
| Q40755882 | PTEN sensitizes prostate cancer cells to death receptor-mediated and drug-induced apoptosis through a FADD-dependent pathway. |
| Q35146572 | PTEN signaling pathways in melanoma |
| Q36753139 | PTEN, more than the AKT pathway |
| Q34540849 | PTEN: The down side of PI 3-kinase signalling. |
| Q28203387 | PTEN: one gene, many syndromes |
| Q38871799 | Palbociclib has antitumour effects on Pten-deficient endometrial neoplasias. |
| Q34699422 | Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair |
| Q36277982 | Progesterone regulates the proliferation of breast cancer cells - in vitro evidence |
| Q35619493 | Prognostic value of tumor suppressors in osteosarcoma before and after neoadjuvant chemotherapy |
| Q41564326 | Prostaglandin E1 Attenuates Pulmonary Artery Remodeling by Activating Phosphorylation of CREB and the PTEN Signaling Pathway |
| Q24613810 | Protean PTEN: form and function |
| Q24604987 | Protein kinases and phosphatases in the control of cell fate |
| Q33882672 | Pten regulates development and lactation in the mammary glands of dairy cows |
| Q34707865 | Pten signaling in gliomas |
| Q64055629 | Recent advances of therapeutic targets based on the molecular signature in breast cancer: genetic mutations and implications for current treatment paradigms |
| Q42428887 | Regulation of axonal growth and neuromuscular junction formation by neuronal phosphatase and tensin homologue signaling |
| Q35912453 | Regulation of nuclear TDP-43 by NR2A-containing NMDA receptors and PTEN. |
| Q34921868 | Regulation of the tumor suppressor PTEN through exosomes: a diagnostic potential for prostate cancer |
| Q34261684 | Retracted: SPARC Overexpression Inhibits Cell Proliferation in Neuroblastoma and Is Partly Mediated by Tumor Suppressor Protein PTEN and AKT |
| Q24794042 | Retroviral expression of a kinase-defective IGF-I receptor suppresses growth and causes apoptosis of CHO and U87 cells in-vivo |
| Q42452984 | Role of PTEN and Akt in the regulation of growth and apoptosis in human osteoblastic cells |
| Q44504090 | SHIP-2 and PTEN are expressed and active in vascular smooth muscle cell nuclei, but only SHIP-2 is associated with nuclear speckles |
| Q34565498 | Steroid hormone mimics: molecular mechanisms of cell growth and apoptosis in normal and malignant mammary epithelial cells |
| Q30391301 | Structural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancer |
| Q35010842 | Suppression of gastric cancer growth by adenovirus-mediated transfer of the PTEN gene |
| Q37223362 | Synthetic lethal targeting of PTEN-deficient cancer cells using selective disruption of polynucleotide kinase/phosphatase |
| Q37026584 | TBX2 represses PTEN in rhabdomyosarcoma and skeletal muscle |
| Q37405633 | Targeting EGFR resistance networks in head and neck cancer. |
| Q35970384 | The Rho Guanine Nucleotide Exchange Factor DRhoGEF2 Is a Genetic Modifier of the PI3K Pathway in Drosophila |
| Q35976355 | The complexity of PTEN: mutation, marker and potential target for therapeutic intervention |
| Q38791765 | The miR-21/PTEN/Akt signaling pathway is involved in the anti-tumoral effects of zoledronic acid in human breast cancer cell lines. |
| Q27852764 | Therapeutic targeting of cancers with loss of PTEN function |
| Q57741132 | Trichilemmomas show loss of PTEN in Cowden syndrome but only rarely in sporadic tumors |
| Q38098152 | When Overgrowth Bumps Into Cancer: The PTEN-Opathies |
| Q51046620 | When overgrowth bumps into cancer: the PTEN-opathies. |
| Q35745141 | p27 deregulation in breast cancer: prognostic significance and implications for therapy |
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