Neferine, an alkaloid from lotus seed embryo, inhibits human lung cancer cell growth by MAPK activation and cell cycle arrest. (scientific article published on 24 August 2013)

Preparative counter-current chromatography isolation of liensinine and its analogues from embryo of the seed of Nelumbo nucifera GAERTN. using upright coil planet centrifuge with four multilayer coils connected in series.

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Neferine inhibits cultured hepatic stellate cell activation and facilitates apoptosis: A possible molecular mechanism

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Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis

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A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry.

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Reactive oxygen species are downstream mediators of p53-dependent apoptosis

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Apoptosis and lung cancer: a review

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Neferine, an alkaloid ingredient in lotus seed embryo, inhibits proliferation of human osteosarcoma cells by promoting p38 MAPK-mediated p21 stabilization.

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Curcumin enhances the mitomycin C-induced cytotoxicity via downregulation of MKK1/2-ERK1/2-mediated Rad51 expression in non-small cell lung cancer cells

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Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis

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Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling

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ERK and JNK mediate TNFalpha-induced p53 activation in apoptotic and autophagic L929 cell death

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Interferon-gamma modulates a p53-independent apoptotic pathway and apoptosis-related gene expression

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Green tea (-)-epigallocatechin gallate inhibits IGF-I and IGF-II stimulation of 3T3-L1 preadipocyte mitogenesis via the 67-kDa laminin receptor, but not AMP-activated protein kinase pathway

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Neferine induces reactive oxygen species mediated intrinsic pathway of apoptosis in HepG2 cells

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Fresh apples suppress mammary carcinogenesis and proliferative activity and induce apoptosis in mammary tumors of the Sprague-Dawley rat.

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Selenium: Biochemical Role as a Component of Glutathione Peroxidase

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P433

issue

P407

language of work or name

English

Q1860

P921

main subject

lung cancer

Q47912

cell growth

Q189159

P304

page(s)

121-131

P577

publication date

2013-08-24

P1433

published in

BioFactors

Q15767404

P1476

title

Neferine, an alkaloid from lotus seed embryo, inhibits human lung cancer cell growth by MAPK activation and cell cycle arrest

P478

volume

Reverse relations

cites work (P2860)

Q38964334	A Comprehensive Review on Chemical Profiling of Nelumbo Nucifera: Potential for Drug Development.
Q58608082	Benzylisoquinoline Alkaloids Biosynthesis in Sacred Lotus
Q26744523	Current Advances in the Metabolomics Study on Lotus Seeds
Q38732105	Cytotoxic, Antitumor and Immunomodulatory Effects of the Water-Soluble Polysaccharides from Lotus (Nelumbo nucifera Gaertn.) Seeds.
Q37614624	Digital Gene Expression Analysis Provides Insight into the Transcript Profile of the Genes Involved in Aporphine Alkaloid Biosynthesis in Lotus (Nelumbo nucifera).
Q55091542	Investigation of benzylisoquinoline alkaloid biosynthetic pathway and its transcriptional regulation in lotus.
Q36667033	Liensinine- and Neferine-Induced Cardiotoxicity in Primary Neonatal Rat Cardiomyocytes and Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Q42240230	Mode of Action Analyses of Neferine, a Bisbenzylisoquinoline Alkaloid of Lotus (Nelumbo nucifera) against Multidrug-Resistant Tumor Cells.
Q48093207	Neferine Enhances the Antitumor Effect of Mitomycin-C in Hela Cells Through the Activation of p38-MAPK Pathway.
Q48220826	Neferine Potentiates the Antitumor Effect of Cisplatin in Human Lung Adenocarcinoma Cells Via a Mitochondria-Mediated Apoptosis Pathway.
Q52727749	Neferine Protects Endothelial Glycocalyx via Mitochondrial ROS in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome.
Q42363693	Neferine ameliorates cardiomyoblast apoptosis induced by doxorubicin: possible role in modulating NADPH oxidase/ROS-mediated NFκB redox signaling cascade
Q38806119	Neferine induces autophagy of human ovarian cancer cells via p38 MAPK/ JNK activation.
Q92290128	Neferine induces autophagy-dependent cell death in apoptosis-resistant cancers via ryanodine receptor and Ca2+-dependent mechanism
Q37641668	Neferine inhibits proliferation and collagen synthesis induced by high glucose in cardiac fibroblasts and reduces cardiac fibrosis in diabetic mice
Q38781040	Neferine prevents NF-κB translocation and protects muscle cells from oxidative stress and apoptosis induced by hypoxia.
Q91712533	Neferine prevents ultraviolet radiation-induced skin photoaging
Q92142394	Neferine treatment enhances the TRAIL‑induced apoptosis of human prostate cancer cells via autophagic flux and the JNK pathway
Q56453746	Nelumbo nucifera
Q47929712	Nelumbo nucifera leaf extract treatment attenuated preneoplastic lesions and oxidative stress in the livers of diethylnitrosamine-treated rats
Q36457188	Phytochemical Profile and Biological Activity of Nelumbo nucifera.
Q55317179	Suppressive Effects of Vaccinium angustifolium Root Extract via Down-Regulation of Activation of Syk, Lyn, and NF-κB in FcɛRI-Mediated Allergic Reactions.
Q38426104	Taurine, a major amino acid of oyster, enhances linear bone growth in a mouse model of protein malnutrition
Q26749391	Tetrandrine, a Chinese plant-derived alkaloid, is a potential candidate for cancer chemotherapy
Q37612719	The anti-tumor activities of Neferine on cell invasion and oxaliplatin sensitivity regulated by EMT via Snail signaling in hepatocellular carcinoma
Q53427956	[Advances in the Research of the Regulation of Chinese Traditional Medicine Monomer and Its Derivatives on Autophagy in Non-small Cell Lung Cancer].

P356	DOI	10.1002/BIOF.1115
P8608	Fatcat ID	release_kpl2qaitebbodmu5m2h3mdcvnq
P698	PubMed publication ID	23983146
P5875	ResearchGate publication ID	256189193