Progesterone regulates the proliferation of breast cancer cells - in vitro evidence

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Progesterone regulates the proliferation of breast cancer cells - in vitro evidence is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2147/DDDT.S89390
P932PMC publication ID4644174
P698PubMed publication ID26609221

P2093author name stringIndhu Hariharan
Jem Prabhakar
Hima Sithul
Sreeja Sreekumar
Juberiya M Azeez
Madhavan Radhakrishna Pillai
Sreeharshan Sreeja
P2860cites workTwo distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and BQ24556548
Molecular determinants of context-dependent progesterone receptor action in breast cancerQ26997928
PTEN regulation of ERK1/2 signaling in cancerQ27011088
PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanismsQ28181035
PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer modelQ32069431
Timing of surgery for primary breast cancer with regard to the menstrual phase and prognosisQ33538451
Suppression of human lung cancer cell proliferation and metastasis in vitro by the transducer of ErbB-2.1 (TOB1).Q33567280
Progesterone action in human tissues: regulation by progesterone receptor (PR) isoform expression, nuclear positioning and coregulator expressionQ33595229
Hypothesis: Progesterone primes breast cancer cells for cross-talk with proliferative or antiproliferative signalsQ33668753
SOD1, an unexpected novel target for cancer therapyQ33776847
Estrogen and progestin regulation of cell cycle progressionQ33923687
Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosisQ34371260
Impact of oestradiol and progesterone on antioxidant activity in normal human breast epithelial cells in culture.Q50872641
Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas.Q52180037
Colocalization of Progesterone Receptors A and B by Dual Immunofluorescent Histochemistry in Human Endometrium during the Menstrual Cycle1Q60662131
Natural killer cell activity: age, estrous- and circadian-stage dependence and inverse correlation with metastatic potentialQ68097526
Timing of surgery during menstrual cycle and survival of premenopausal women with operable breast cancerQ68299182
PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2)Q73617626
PTEN transcriptionally modulates c-myc gene expression in human breast carcinoma cells and is involved in cell growth regulationQ78026206
Estrogen and oxidative stressQ80512214
Breast cancer--loss of PTEN predicts resistance to treatmentQ81059127
Re: Mastectomy and oophorectomy by menstrual cycle phase in women with operable breast cancerQ94158597
Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breastQ35788322
Estrous influence on surgical cure of a mouse breast cancerQ36355139
Control of cyclin D1, p27(Kip1), and cell cycle progression in human capillary endothelial cells by cell shape and cytoskeletal tensionQ36921506
Reactive oxygen species in cancerQ37431048
Progestin regulation of cellular proliferationQ37818260
The role of surgery in metastatic breast cancerQ37937931
Endocrine treatment of breast cancer in womenQ37938852
Tumor suppressor genes and ROS: complex networks of interactionsQ37948470
The ERalpha/ERbeta ratio determines oxidative stress in breast cancer cell lines in response to 17beta-estradiol.Q39344606
Progesterone inhibits growth and induces apoptosis in cancer cells through modulation of reactive oxygen speciesQ39617962
TOB suppresses breast cancer tumorigenesisQ39830658
Mechanisms of hormone resistance in breast cancerQ40770822
Convergence of progesterone and epidermal growth factor signaling in breast cancer. Potentiation of mitogen-activated protein kinase pathwaysQ40995230
Biphasic regulation of breast cancer cell growth by progesterone: role of the cyclin-dependent kinase inhibitors, p21 and p27(Kip1).Q41084288
Timing of Breast Cancer Excision during the Menstrual Cycle Influences Duration of Disease-free SurvivalQ41157197
Menstrual influence on surgical cure of breast cancerQ41218759
Progesterone regulates transcription of the p21(WAF1) cyclin- dependent kinase inhibitor gene through Sp1 and CBP/p300.Q42454022
Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancerQ43675669
The influence of menstrual cycle phase on surgical treatment of primary breast cancer: have we made any progress over the past 13 years?Q43976265
Mastectomy and oophorectomy by menstrual cycle phase in women with operable breast cancerQ43976269
Subnuclear distribution of progesterone receptors A and B in normal and malignant endometriumQ44787029
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)5987-5999
P577publication date2015-11-09
P1433published inDrug Design, Development and TherapyQ2566724
P1476titleProgesterone regulates the proliferation of breast cancer cells - in vitro evidence
P478volume9

Reverse relations

cites work (P2860)
Q47891451Cytoplasmic translocation of MTA1 coregulator promotes de-repression of SGK1 transcription in hypoxic cancer cells
Q52669327Estrogen and progesterone promote breast cancer cell proliferation by inducing cyclin G1 expression.
Q37267043Progesterone influences cytoplasmic maturation in porcine oocytes developing in vitro.
Q58597684Up-regulation of the kinase gene by progesterone activates the AP-1-NDRG1 axis in both PR-positive and -negative breast cancer cells

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