scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1050827505 |
P356 | DOI | 10.1038/APS.2011.163 |
P932 | PMC publication ID | 4010328 |
P698 | PubMed publication ID | 22158108 |
P5875 | ResearchGate publication ID | 51868151 |
P2093 | author name string | Lin Zhao | |
Yang Jiao | |||
Sai-jun Fan | |||
Li-li Wang | |||
Jia-ying Xu | |||
Ke-kang Sun | |||
P2860 | cites work | Global cancer statistics | Q22241238 |
Tob, a novel protein that interacts with p185erbB2, is associated with anti-proliferative activity | Q24311733 | ||
KRAS, BRAF, PIK3CA, and PTEN mutations: implications for targeted therapies in metastatic colorectal cancer. | Q27851616 | ||
Negative regulation of BMP/Smad signaling by Tob in osteoblasts | Q28143428 | ||
Alteration of expression or phosphorylation status of tob, a novel tumor suppressor gene product, is an early event in lung cancer | Q28187810 | ||
Tob proteins enhance inhibitory Smad-receptor interactions to repress BMP signaling | Q28208130 | ||
The mammalian anti-proliferative BTG/Tob protein family | Q28258172 | ||
PI3K/PTEN signaling in angiogenesis and tumorigenesis | Q28383083 | ||
Metastasis suppressor genes at the interface between the environment and tumor cell growth | Q28394526 | ||
PTEN can inhibit in vitro organotypic and in vivo orthotopic invasion of human bladder cancer cells even in the absence of its lipid phosphatase activity | Q30434033 | ||
Oncogenes and tumor suppressor genes | Q34149922 | ||
A new look at TCF and beta-catenin through the lens of a divergent C. elegans Wnt pathway | Q34535107 | ||
Intervening in β-catenin signaling by sulindac inhibits S100A4-dependent colon cancer metastasis | Q34551546 | ||
Mice lacking a transcriptional corepressor Tob are predisposed to cancer | Q35965343 | ||
Tob genes in development and homeostasis | Q36737268 | ||
PTEN, more than the AKT pathway | Q36753139 | ||
PTEN mutation: many birds with one stone in tumorigenesis. | Q37384428 | ||
Tob, a member of the APRO family, regulates immunological quiescence and tumor suppression | Q37409167 | ||
Combined inhibition of the VEGFR and EGFR signaling pathways in the treatment of NSCLC. | Q37439082 | ||
BTG/TOB factors impact deadenylases | Q37455743 | ||
Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia. | Q37582684 | ||
Generation of tolerogenic dendritic cells via the E-cadherin/beta-catenin-signaling pathway | Q37601348 | ||
Coordinate action of membrane-type matrix metalloproteinase-1 (MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion | Q37690802 | ||
Lung cancer progression and metastasis from the prognostic point of view. | Q37708137 | ||
Molecular mechanism of pancreatic cancer--understanding proliferation, invasion, and metastasis | Q37711135 | ||
Adenovirus-mediated expression of UHRF1 reduces the radiosensitivity of cervical cancer HeLa cells to gamma-irradiation | Q37727961 | ||
Knockdown of FoxM1 by siRNA interference decreases cell proliferation, induces cell cycle arrest and inhibits cell invasion in MHCC-97H cells in vitro | Q37728188 | ||
Strategies for overcoming inherent and acquired resistance to EGFR inhibitors by targeting downstream effectors in the RAS/PI3K pathway | Q37780773 | ||
Regulation of VSMC behavior by the cadherin-catenin complex. | Q37825170 | ||
Doubles Game: Src-Stat3 versus p53-PTEN in Cellular Migration and Invasion | Q38341405 | ||
Brain pericytes among cells constituting the blood-brain barrier are highly sensitive to tumor necrosis factor-α, releasing matrix metalloproteinase-9 and migrating in vitro | Q38590785 | ||
Oleic acid promotes MMP-9 secretion and invasion in breast cancer cells. | Q39682416 | ||
Effect of wild type PTEN gene on proliferation and invasion of multiple myeloma | Q39687681 | ||
TOB suppresses breast cancer tumorigenesis | Q39830658 | ||
TOB1 is regulated by EGF-dependent HER2 and EGFR signaling, is highly phosphorylated, and indicates poor prognosis in node-negative breast cancer | Q39843653 | ||
Tumor growth suppression by adenovirus-mediated introduction of a cell-growth-suppressing gene tob in a pancreatic cancer model | Q39957051 | ||
Dysregulated PI3K/Akt/PTEN pathway is a marker of a short disease-free survival in node-negative breast carcinoma | Q42453448 | ||
Tob is a potential marker gene for the basal layer of the epidermis and is stably expressed in human primary keratinocytes | Q42490158 | ||
Deficiency of antiproliferative family protein Ana correlates with development of lung adenocarcinoma | Q42805237 | ||
Down-regulation of MMP-2 through the p38 MAPK-NF-kappaB-dependent pathway by aloe-emodin leads to inhibition of nasopharyngeal carcinoma cell invasion | Q42979728 | ||
A nonreplicating adenoviral vector that contains the wild-type p53 transgene combined with chemotherapy for primary breast cancer: safety, efficacy, and biologic activity of a novel gene-therapy approach | Q45861413 | ||
Both lipid- and protein-phosphatase activities of PTEN contribute to the p53-PTEN anti-invasion pathway | Q45908947 | ||
Molecular mechanisms of metastasis. | Q46055814 | ||
Coalterations of p53 and PTEN tumor suppressor genes in non-small cell lung carcinoma patients | Q46710025 | ||
Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal beta-catenin transcriptional activity. | Q47073575 | ||
Increased nuclear factor-kB activation in human colorectal carcinoma and its correlation with tumor progression. | Q47435485 | ||
Dihydroartemisinin is an inhibitor of ovarian cancer cell growth | Q47776445 | ||
The negative cell cycle regulator, Tob (transducer of ErbB-2), is involved in motor skill learning | Q48686904 | ||
PTEN mutations and relationship to EGFR, ERBB2, KRAS, and TP53 mutations in non-small cell lung cancers. | Q53486364 | ||
Molecular alterations of E-cadherin and beta-catenin in brain metastases. | Q54394542 | ||
The mammalian target of rapamycin pathway is widely activated without PTEN deletion in renal cell carcinoma metastases. | Q54650775 | ||
EGFR and HER3 mRNA expression levels predict distant metastases in locally advanced rectal cancer | Q54651225 | ||
Adenovirus-mediated expression of Tob1 sensitizes breast cancer cells to ionizing radiation | Q64376960 | ||
Plasma matrix metalloproteinase-9 level is better than serum matrix metalloproteinase-9 level to predict gastric cancer evolution | Q80087614 | ||
Phosphorylation and inactivation of Tob contributes to the progression of papillary carcinoma of the thyroid | Q81520552 | ||
PI(3)K/PTEN/AKT pathway | Q82943406 | ||
P433 | issue | 2 | |
P921 | main subject | lung cancer | Q47912 |
P304 | page(s) | 250-260 | |
P577 | publication date | 2011-12-12 | |
P1433 | published in | Acta Pharmacologica Sinica | Q15749885 |
P1476 | title | Suppression of human lung cancer cell proliferation and metastasis in vitro by the transducer of ErbB-2.1 (TOB1). | |
P478 | volume | 33 |
Q55356398 | Association between the SNPs of the TOB1 gene and gastric cancer risk in the Chinese Han population of northeast China. |
Q45845716 | Decreased TOB1 expression and increased phosphorylation of nuclear TOB1 promotes gastric cancer |
Q88778854 | Dipeptidyl peptidase IV (DPP-4) inhibition alleviates pulmonary arterial remodeling in experimental pulmonary hypertension |
Q47957465 | Exposure to PM2.5 causes genetic changes in fetal rat cerebral cortex and hippocampus |
Q36360773 | Influence of nanoparticle-mediated transfection on proliferation of primary immune cells in vitro and in vivo |
Q34583846 | Long intergenic non-coding RNA induced by X-ray irradiation regulates DNA damage response signaling in the human bronchial epithelial BEAS-2B cell line |
Q87417424 | MicroRNA-25 promotes gastric cancer migration, invasion and proliferation by directly targeting transducer of ERBB2, 1 and correlates with poor survival |
Q93187723 | Phosphorylation of TOB1 at T172 and S320 is critical for gastric cancer proliferation and progression |
Q36277982 | Progesterone regulates the proliferation of breast cancer cells - in vitro evidence |
Q92348278 | TOB1 suppresses proliferation in K-Ras wild-type pancreatic cancer |
Q36633354 | The Fto Gene Regulates the Proliferation and Differentiation of Pre-Adipocytes in Vitro |
Q38819414 | The polymorphism in miR-25 attenuated the oncogenic function in gastric cancer |
Q38834886 | Tob1 enhances radiosensitivity of breast cancer cells involving the JNK and p38 pathways |
Q36639904 | Tob1 induces apoptosis and inhibits proliferation, migration and invasion of gastric cancer cells by activating Smad4 and inhibiting β‑catenin signaling |
Q26773429 | Transducer of ERBB2.1 (TOB1) as a Tumor Suppressor: A Mechanistic Perspective |
Q42416926 | Transducer of erbB2.1 is a potential cellular target of gefitinib in lung cancer therapy |
Q42260667 | miRNA-32 Drives Brown Fat Thermogenesis and Trans-activates Subcutaneous White Fat Browning in Mice. |
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