Mechanisms of hormone resistance in breast cancer

scientific article

Mechanisms of hormone resistance in breast cancer is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1019965929
P356DOI10.1007/BF00689685
P698PubMed publication ID8219249
P5875ResearchGate publication ID14980531

P2093author name stringK B Horwitz
P2860cites workComplete amino acid sequence of the human progesterone receptor deduced from cloned cDNAQ24299325
Sequence and expression of human estrogen receptor complementary DNAQ24299678
Genomic organization of the human oestrogen receptor geneQ24564158
Estrogen receptor expression in human breast cancer associated with an estrogen receptor gene restriction fragment length polymorphismQ69366751
Genomic DNA analysis of the estrogen receptor gene in breast cancerQ69377616
Human breast cancer in the athymic nude mouse: cytostatic effects of long-term antiestrogen therapyQ69397268
Tissue-specific regulation of rat estrogen receptor mRNAsQ69617471
Simultaneous measurement of progesterone receptors and DNA indices by flow cytometry: characterization of an assay in breast cancer cell linesQ69636971
Chemoprevention for breast cancer: are we ready?Q70120449
Is a functional estrogen receptor always required for progesterone receptor induction in breast cancer?Q71100427
Characterization of estrogen receptor variant mRNAs from human breast cancersQ28262735
Evidence for a previously unidentified upstream exon in the human oestrogen receptor geneQ28273041
Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-AQ29619449
Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor.Q33880351
Truncated forms of DNA-binding estrogen receptors in human breast cancerQ34194960
Development of antiestrogens and their use in breast cancer: eighth Cain memorial award lectureQ34219324
Establishment and characterization of a cell line of human breast carcinoma originQ34294071
T47DCO cells, genetically unstable and containing estrogen receptor mutations, are a model for the progression of breast cancers to hormone resistance.Q34979932
Cloning of the chicken progesterone receptorQ35050960
Molecular cloning of the chicken progesterone receptorQ35051358
The Molecular Biology of RU486. Is There a Role for Antiprogestins in the Treatment of Breast Cancer?*Q36266619
Estrogen receptor variants in human breast cancerQ37796937
Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP.Q38319428
Binding analysis of the estrogen receptor to its specific DNA target site in human breast cancer.Q38334441
Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptorQ38341530
Steroid hormone antagonists at the receptor level: a role for the heat-shock protein MW 90,000 (hsp 90).Q39690695
Predicting Response to Endocrine Therapy in Human Breast Cancer: A HypothesisQ39945174
An assessment of current achievements in the systemic management of breast cancerQ40181973
Tamoxifen-induced tumor stimulation and withdrawal responseQ40285008
Identification of a variant form of the human estrogen receptor with an amino acid replacementQ40538303
PvuII RFLP inside the human estrogen receptor geneQ40564888
A domain containing leucine-zipper-like motifs mediate novel in vivo interactions between the thyroid hormone and retinoic acid receptorsQ41274369
Heterogeneity of progesterone receptor content and remodeling by tamoxifen characterize subpopulations of cultured human breast cancer cells: analysis by quantitative dual parameter flow cytometryQ41640879
A single nucleotide substitution in the D domain of estrogen receptor cDNA causes amino acid alteration from Glu-279 to Lys-279 in a murine transformed leydig cell line (B-1 F)Q41677862
Mechanisms involved in the evolution of progestin resistance in human breast cancer cellsQ41687697
Interaction of growth factors during progression towards steroid independence in T-47-D human breast cancer cellsQ42481485
Proliferation, hormonal responsiveness, and estrogen receptor content of MCF-7 human breast cancer cells grown in the short-term and long-term absence of estrogensQ42523366
Nuclear estrogen receptor release from antiestrogen suppression: amplified induction of progesterone receptor in MCF-7 human breast cancer cellsQ43411264
Uterine estrogen receptor in vivo: phosphorylation of nuclear specific forms on serine residuesQ43656969
The N-terminal region of the chicken progesterone receptor specifies target gene activationQ43762001
Resistance to endocrine therapy. A panel discussionQ44224117
Oestrogen receptor B-region polymorphism and spontaneous abortion in women with breast cancerQ44524956
Simultaneous measurement of progesterone receptors and DNA indices by flow cytometry: analysis of breast cancer cell mixtures and genetic instability of the T47D lineQ44638074
Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domainQ46401096
Acquired tamoxifen resistance: correlation with reduced breast tumor levels of tamoxifen and isomerization of trans-4-hydroxytamoxifen.Q54286500
Inhibition of tamoxifen-stimulated growth of an MCF-7 tumor variant in athymic mice by novel steroidal antiestrogens.Q54347791
Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long-term antiestrogen administrationQ54376589
A variant estrogen receptor messenger ribonucleic acid is associated with reduced levels of estrogen binding in human mammary tumors.Q54378273
Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance.Q54519992
Receptors bound to antiprogestin form abortive complexes with hormone responsive elementsQ59081172
Estrogen control of progesterone receptor in human breast cancer. Correlation with nuclear processing of estrogen receptorQ67294717
Steroid receptor analyses of nine human breast cancer cell linesQ67351998
The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimerQ67927526
Variant human breast tumor estrogen receptor with constitutive transcriptional activityQ68183370
Tamoxifen prevents the skeletal effects of ovarian hormone deficiency in ratsQ68718298
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)119-130
P577publication date1993-01-01
P1433published inBreast Cancer Research and TreatmentQ326085
P1476titleMechanisms of hormone resistance in breast cancer
P478volume26

Reverse relations

cites work (P2860)
Q34973200"Resurrection of clinical efficacy" after resistance to endocrine therapy in metastatic breast cancer
Q55263007Allelic loss on chromosome 9q is associated with lymph node metastasis of primary breast cancer.
Q33871478Altering the estrogenic milieu of breast cancer with a focus on the new aromatase inhibitors
Q42142801Association of genetic alterations on chromosome 17 and loss of hormone receptors in breast cancer
Q37144740Basic evidence of molecular targeted therapy for oral cancer and salivary gland cancer
Q54065301Bcar1/p130Cas protein and primary breast cancer: prognosis and response to tamoxifen treatment.
Q36569036Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth
Q43838221Deaths from breast cancer: tackling multidimensionality and non-linearity by correspondence analysis
Q35834174Differential expression of estrogen, progesterone, and epidermal growth factor receptors in normal, benign, and malignant human breast tissues using dual staining immunohistochemistry.
Q43840233Effect of phosphatidic acid on human breast cancer cells exposed to doxorubicin
Q73305002Estrogen receptor variants ERdelta5 and ERdelta7 down-regulate wild-type estrogen receptor activity
Q28396413Estrogen withdrawal-induced NF-kappaB activity and bcl-3 expression in breast cancer cells: roles in growth and hormone independence
Q40568066Flow cytometry: potential utility in monitoring drug effects in breast cancer
Q34403755Genetic mechanisms of estrogen-independence in breast cancer
Q43588994High performance liquid chromatographic determination of 123-I labeled tamoxifen metabolites in human plasma
Q60357515Hormonal therapy of breast cancer
Q53448388Hormone dependence of mammary tumors induced in rats by intraperitoneal NMU injection.
Q24314806Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells
Q28246373Identification of a novel breast-cancer-anti-estrogen-resistance (BCAR2) locus by cell-fusion-mediated gene transfer in human breast-cancer cells
Q41463854Insulin-like growth factors in breast cancer
Q73503412Lack of relationship between the expression of Hsp27 heat shock estrogen receptor-associated protein and estrogen receptor or progesterone receptor status in male breast carcinoma
Q44071038Loss of heterozygosity at pseudoautosomal regions in human breast cancer and association with negative hormonal phenotype
Q34007012New generation aromatase inhibitors in breast cancer. Weighing out potential costs and benefits
Q39491094Novel therapeutic strategies for malignant salivary gland tumors: lessons learned from breast cancer
Q36672230Oestrogen signalling inhibits invasive phenotype by repressing RelB and its target BCL2.
Q36081930Outgrowth of BT-474 human breast cancer cells in immune-deficient mice: a new in vivo model for hormone-dependent breast cancer
Q46082739Polyamine inhibition of estrogen receptor (ER) DNA-binding and ligand-binding functions
Q36277982Progesterone regulates the proliferation of breast cancer cells - in vitro evidence
Q72875667Reduced tamoxifen accumulation is not associated with stimulated growth in tamoxifen resistance
Q36080684Relationship of PS2 with response to tamoxifen therapy in patients with recurrent breast cancer
Q77579571Tamoxifen aziridine binding to cytosolic proteins from human breast specimens is negatively associated with estrogen receptors, progesterone receptors, pS2, and cathepsin-D
Q42540015Tamoxifen inhibits nitrobenzylthioinosine-sensitive equilibrative uridine transport in human MCF-7 breast cancer cells
Q34427746Tamoxifen resistance in breast cancer: elucidating mechanisms
Q40240263Thymine-rich single-stranded DNA activates Mcm4/6/7 helicase on Y-fork and bubble-like substrates
Q71760922Two distinct commonly deleted regions on chromosome 13q suggest involvement of BRCA2 and retinoblastoma genes in sporadic breast carcinomas
Q44664467Variant liver estrogen receptor transcripts already occur at an early stage of chronic liver disease