| scholarly article | Q13442814 |
| P50 | author | Cimona V Hinton | Q59700831 |
| P2093 | author name string | Mahandranauth A Chetram | |
| P2860 | cites work | Requirement of STAT3 activation for differentiation of mucosal stratified squamous epithelium | Q22305869 |
| The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation | Q24290417 | ||
| NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN | Q24292919 | ||
| The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
| Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN | Q24322051 | ||
| P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
| Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions | Q24532168 | ||
| The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo | Q24657924 | ||
| PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
| PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway | Q28139300 | ||
| PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms | Q28181035 | ||
| The biology and clinical relevance of the PTEN tumor suppressor pathway | Q28272157 | ||
| Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1 | Q28283323 | ||
| Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
| Loss of PTEN permits CXCR4-mediated tumorigenesis through ERK1/2 in prostate cancer cells | Q28388722 | ||
| Regulation of PTEN transcription by p53 | Q28646911 | ||
| Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases | Q29618331 | ||
| Angiogenesis in prostate cancer: biology and therapeutic opportunities | Q30309574 | ||
| PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model | Q32069431 | ||
| Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer | Q34043823 | ||
| PTEN loss induces epithelial--mesenchymal transition in human colon cancer cells. | Q34100984 | ||
| PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling. | Q34133079 | ||
| Cooperative interactions of PTEN deficiency and RAS activation in melanoma metastasis | Q34338564 | ||
| ROS enhances CXCR4-mediated functions through inactivation of PTEN in prostate cancer cells | Q35185336 | ||
| Redox regulation of PI 3-kinase signalling via inactivation of PTEN | Q36266420 | ||
| Shc and FAK differentially regulate cell motility and directionality modulated by PTEN. | Q36301565 | ||
| The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions | Q36360691 | ||
| Tumor suppressor genes in breast cancer: the gatekeepers and the caretakers | Q36391987 | ||
| PTEN: a default gate-keeping tumor suppressor with a versatile tail | Q37216319 | ||
| Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy. | Q37865381 | ||
| Regulation of MEK/ERK pathway output by subcellular localization of B-Raf | Q37977165 | ||
| Kaposi's sarcoma-associated herpesvirus induces the phosphatidylinositol 3-kinase-PKC-zeta-MEK-ERK signaling pathway in target cells early during infection: implications for infectivity | Q38359214 | ||
| Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes. | Q39574246 | ||
| MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC). | Q39728869 | ||
| PTEN expression controls cellular response to cetuximab by mediating PI3K/AKT and RAS/RAF/MAPK downstream signaling in KRAS wild-type, hormone refractory prostate cancer cells | Q39884566 | ||
| PTEN regulates colorectal epithelial apoptosis through Cdc42 signalling | Q39886249 | ||
| Akt inactivates ERK causing decreased response to chemotherapeutic drugs in advanced CaP cells | Q40015639 | ||
| PI3K is required for insulin-stimulated but not EGF-stimulated ERK1/2 activation | Q40331461 | ||
| Regulation of Raf-Akt Cross-talk | Q40727585 | ||
| Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation | Q40732720 | ||
| Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3. | Q42067413 | ||
| Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN. | Q42807109 | ||
| Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase | Q42828607 | ||
| Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN. | Q43621579 | ||
| The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling | Q43848062 | ||
| Segmental analysis of molecular surface electrostatic potentials: application to enzyme inhibition | Q44411792 | ||
| PTEN promoter methylation in sporadic thyroid carcinomas | Q48645805 | ||
| p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1. | Q52173333 | ||
| EGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis. | Q53292368 | ||
| Localization of the gene for Cowden disease to chromosome 10q22–23 | Q57694734 | ||
| Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma | Q71970954 | ||
| PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway | Q74404969 | ||
| Promoter methylation of the PTEN gene is a common molecular change in breast cancer | Q80403566 | ||
| PTEN promoter methylation and LOH of 10q22-23 locus in PTEN expression of ovarian clear cell adenocarcinomas | Q82600359 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 190-195 | |
| P577 | publication date | 2012-06-28 | |
| P1433 | published in | Journal of Receptors and Signal Transduction | Q6295837 |
| P1476 | title | PTEN regulation of ERK1/2 signaling in cancer | |
| P478 | volume | 32 |
| Q37324522 | A PTEN inhibitor displays preclinical activity against hepatocarcinoma cells |
| Q55237889 | Advances in prostate cancer research models: From transgenic mice to tumor xenografting models. |
| Q48625073 | Ammonium Increases TRPC1 Expression Via Cav-1/PTEN/AKT/GSK3β Pathway |
| Q34733234 | Aquaporin-8 mediates human esophageal cancer Eca-109 cell migration via the EGFR-Erk1/2 pathway |
| Q38963912 | Complex interactions between the components of the PI3K/AKT/mTOR pathway, and with components of MAPK, JAK/STAT and Notch-1 pathways, indicate their involvement in meningioma development. |
| Q39210082 | Effect of PTEN antisense oligonucleotide on oesophageal squamous cell carcinoma cell lines |
| Q98238826 | Efficient miRNA Inhibitor with GO-PEI Nanosheets for Osteosarcoma Suppression by Targeting PTEN |
| Q47756248 | Emerging roles of syndecan 2 in epithelial and mesenchymal cancer progression |
| Q35865016 | Epstein-Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating PTEN-dependent pathways in nasopharyngeal carcinoma |
| Q52340925 | Exosomes in Nasopharyngeal Carcinoma. |
| Q34029036 | Expression of aquaporin 8 and phosphorylation of Erk1/2 in cervical epithelial carcinogenesis: correlation with clinicopathological parameters |
| Q92422244 | Extracellular Signal-Regulated Kinase: A Regulator of Cell Growth, Inflammation, Chondrocyte and Bone Cell Receptor-Mediated Gene Expression |
| Q51150179 | Extracellular signal-regulated kinase (ERK) expression and activation in mobile tongue squamous cell carcinoma: associations with clinicopathological parameters and patients survival. |
| Q36244298 | Focal Adhesion Kinase: Insight into Molecular Roles and Functions in Hepatocellular Carcinoma |
| Q52776751 | Glioblastoma multiforme-derived extracellular vesicles drive normal astrocytes towards a tumour-enhancing phenotype. |
| Q28387600 | Global DNA methylation and PTEN hypermethylation alterations in lung tissues from human silicosis |
| Q38910573 | High SIPA-1 expression in proximal tubules of human kidneys under pathological conditions |
| Q45190761 | Human sulfatase-1 inhibits the migration and proliferation of SMMC-7721 hepatocellular carcinoma cells by downregulating the growth factor signaling |
| Q35790612 | Inhibiting ERK Activation with CI-1040 Leads to Compensatory Upregulation of Alternate MAPKs and Plasminogen Activator Inhibitor-1 following Subtotal Nephrectomy with No Impact on Kidney Fibrosis |
| Q35276335 | Involvement of phosphatase and tensin homolog deleted from chromosome 10 in rodent model of neuropathic pain. |
| Q38830812 | Isorhapontigenin induced cell growth inhibition and apoptosis by targeting EGFR-related pathways in prostate cancer. |
| Q34558936 | Klf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathways |
| Q47127001 | Low concentration of formononetin promotes proliferation of estrogen receptor-positive cells through an ERα-miR-375-PTEN-ERK1/2-bcl-2 pathway |
| Q90237363 | Maduramicin induces cardiac muscle cell death by the ROS-dependent PTEN/Akt-Erk1/2 signaling pathway |
| Q33858514 | Metabolic regulation by protein tyrosine phosphatases |
| Q38918343 | MicroRNA-21 controls hTERT via PTEN in human colorectal cancer cell proliferation |
| Q54213961 | MicroRNA-92a promotes tumor growth and suppresses immune function through activation of MAPK/ERK signaling pathway by inhibiting PTEN in mice bearing U14 cervical cancer. |
| Q34714606 | Mig-6 suppresses endometrial cancer associated with Pten deficiency and ERK activation |
| Q53685190 | Notch-1-PTEN-ERK1/2 signaling axis promotes HER2+ breast cancer cell proliferation and stem cell survival. |
| Q41198043 | Overexpression of LRIG1 regulates PTEN via MAPK/MEK signaling pathway in esophageal squamous cell carcinoma |
| Q36948641 | PACAP and VIP Inhibit the Invasiveness of Glioblastoma Cells Exposed to Hypoxia through the Regulation of HIFs and EGFR Expression |
| Q53084404 | PAX6, a novel target of microRNA-7, promotes cellular proliferation and invasion in human colorectal cancer cells. |
| Q90392045 | PTEN loss activates a functional AKT/CXCR4 signaling axis to potentiate tumor growth and lung metastasis in human osteosarcoma cells |
| Q28590466 | PTEN signaling through RAF1 proto-oncogene serine/threonine kinase (RAF1)/ERK in the epididymis is essential for male fertility |
| Q39013961 | Phosphoprotein analysis reveals MEK inhibition as a way to target non-small cell lung cancer tumor initiating cells. |
| Q36277982 | Progesterone regulates the proliferation of breast cancer cells - in vitro evidence |
| Q89729975 | Rapamycin inhibits B-cell activating factor (BAFF)-stimulated cell proliferation and survival by suppressing Ca2+-CaMKII-dependent PTEN/Akt-Erk1/2 signaling pathway in normal and neoplastic B-lymphoid cells |
| Q36356365 | Rapamycin inhibits Erk1/2-mediated neuronal apoptosis caused by cadmium. |
| Q59304352 | Resveratrol inhibits Erk1/2-mediated adhesion of cancer cells via activating PP2A-PTEN signaling network |
| Q97905063 | Serum deprivation initiates adaptation and survival to oxidative stress in prostate cancer cells |
| Q34103347 | Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth |
| Q34987170 | Targeting myristoylated alanine-rich C kinase substrate phosphorylation site domain in lung cancer. Mechanisms and therapeutic implications |
| Q64946489 | The regulatory network of nasopharyngeal carcinoma metastasis with a focus on EBV, lncRNAs and miRNAs. |
| Q38168568 | The signaling pathway of stromal cell-derived factor-1 and its role in kidney diseases |
| Q38701732 | U94 of human herpesvirus 6 down-modulates Src, promotes a partial mesenchymal-to-epithelial transition and inhibits tumor cell growth, invasion and metastasis. |
| Q28592273 | Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes |
| Q59330585 | miR-144/451 cluster plays an oncogenic role in esophageal cancer by inhibiting cell invasion |
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