The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

scientific article

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1101/GAD.1777409
P3181OpenCitations bibliographic resource ID650991
P932PMC publication ID2701585
P698PubMed publication ID19487573
P5875ResearchGate publication ID26258347

P50authorThomas TuschlQ90093
Sara H RouhanifardQ83173599
Eric C HollandQ89747805
Reuven AgamiQ30502648
Cameron BrennanQ30502649
P2093author name stringCarlos le Sage
Jason T Huse
Dolores Hambardzumyan
Cherin Sohn-Lee
Boyoung Wee
John Pena
P2860cites workmiR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cellsQ21245271
MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulatorsQ24336898
A microRNA expression signature of human solid tumors defines cancer gene targetsQ24541455
MicroRNAs: target recognition and regulatory functionsQ24609584
An integrated genomic analysis of human glioblastoma multiformeQ24648860
The impact of microRNAs on protein outputQ24653549
Comprehensive genomic characterization defines human glioblastoma genes and core pathwaysQ24656128
Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferationQ24679746
The 2007 WHO classification of tumours of the central nervous systemQ24685772
Prediction of mammalian microRNA targetsQ27860498
MicroRNA gene expression deregulation in human breast cancerQ27860690
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
Widespread changes in protein synthesis induced by microRNAsQ27860886
MicroRNA signatures in human cancersQ27860962
MicroRNA expression profiles classify human cancersQ28032481
mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastomaQ40407116
Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastomaQ42013793
Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesisQ42827324
PTEN methylation and expression in glioblastomasQ48232099
MicroRNAs and cancerQ48324133
High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma modelQ48456290
PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme.Q55474170
The retinoblastoma gene is involved in malignant progression of astrocytomasQ72853950
MicroRNA signatures in human ovarian cancerQ28249211
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cellsQ28262214
Extensive modulation of a set of microRNAs in primary glioblastomaQ28263314
Osteogenic differentiation of human adipose tissue-derived stem cells is modulated by the miR-26a targeting of the SMAD1 transcription factorQ28264817
MicroRNA-26a targets the histone methyltransferase Enhancer of Zeste homolog 2 during myogenesisQ28269041
microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastomaQ28280337
MYC stimulates EZH2 expression by repression of its negative regulator miR-26aQ28291303
Deregulated expression of miR-26a and Ezh2 in rhabdomyosarcomaQ28304953
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancerQ29547523
A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumorsQ29614399
Ribo-gnome: the big world of small RNAsQ29615681
MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTENQ29616575
Malignant astrocytic glioma: genetics, biology, and paths to treatmentQ29618156
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cellsQ33715154
MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cellsQ34842477
PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivoQ35080265
A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in miceQ35211546
PTEN is a target of chromosome 10q loss in anaplastic oligodendrogliomas and PTEN alterations are associated with poor prognosisQ35746631
Basic fibroblast growth factor induces cell migration and proliferation after glia-specific gene transfer in miceQ35801259
Mechanisms of common fragile site instability.Q36294681
An update on oligodendroglial neoplasmsQ36310485
PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivoQ36453531
Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all.Q36572080
Differential expression of PTEN-targeting microRNAs miR-19a and miR-21 in Cowden syndromeQ36718983
Structural alterations of the epidermal growth factor receptor gene in human gliomasQ36930689
MicroRNAsQ37095827
Pten haploinsufficiency accelerates formation of high-grade astrocytomasQ37384874
MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1).Q38303663
miRNA in situ hybridization in formaldehyde and EDC-fixed tissuesQ39612232
Gli activity correlates with tumor grade in platelet-derived growth factor-induced gliomasQ39996274
MicroRNA-21 targets tumor suppressor genes in invasion and metastasisQ40013848
MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomasQ40073679
P4510describes a project that usesImageJQ1659584
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectmicroRNAQ310899
P304page(s)1327-37
P577publication date2009-06-01
P1433published inGenes & DevelopmentQ1524533
P1476titleThe PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo
P478volume23

Reverse relations

cites work (P2860)
Q38637596A Macro View of MicroRNAs: The Discovery of MicroRNAs and Their Role in Hematopoiesis and Hematologic Disease
Q24632651A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
Q34631552A continuum model for tumour suppression
Q31016573A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).
Q38356196A major role for microRNAs in glioblastoma cancer stem-like cells
Q42230002A miRNA expression signature that separates between normal and malignant prostate tissues.
Q39670048A microRNA Link to Glioblastoma Heterogeneity
Q24633772A systematic review of microRNA in glioblastoma multiforme: micro-modulators in the mesenchymal mode of migration and invasion
Q33869822A ten-microRNA expression signature predicts survival in glioblastoma
Q53079070AKT kinase pathway: a leading target in cancer research.
Q57161414Aberrant miRNAs Regulate the Biological Hallmarks of Glioblastoma
Q37089505Aberrant promoter hypermethylation of PBRM1, BAP1, SETD2, KDM6A and other chromatin-modifying genes is absent or rare in clear cell RCC
Q40498643Ablation of miR-10b Suppresses Oncogene-Induced Mammary Tumorigenesis and Metastasis and Reactivates Tumor-Suppressive Pathways.
Q37226756Acquired copy number alterations of miRNA genes in acute myeloid leukemia are uncommon
Q27005597Adeno-associated virus-mediated microRNA delivery and therapeutics
Q34061489Adult-specific functions of animal microRNAs
Q90570508Alternative polyadenylation confers Pten mRNAs stability and resistance to microRNAs
Q49023583Analysis of EZH2: micro-RNA network in low and high grade astrocytic tumors.
Q37847257Animal models of melanoma: a somatic cell gene delivery mouse model allows rapid evaluation of genes implicated in human melanoma
Q47571295Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model.
Q37736273Antiangiogenic therapy and mechanisms of tumor resistance in malignant glioma
Q42478581Basal and treatment-induced activation of AKT mediates resistance to cell death by AZD6244 (ARRY-142886) in Braf-mutant human cutaneous melanoma cells
Q35388292Bcl-2 promotes malignant progression in a PDGF-B-dependent murine model of oligodendroglioma.
Q57284763Beyond DNA: the Role of Epigenetics in the Premalignant Progression of Breast Cancer
Q35422357CAMTA1 is a novel tumour suppressor regulated by miR-9/9* in glioblastoma stem cells
Q39675624CPEB2, CPEB3 and CPEB4 are coordinately regulated by miRNAs recognizing conserved binding sites in paralog positions of their 3'-UTRs
Q64083820Cell migration and proliferation are regulated by miR-26a in colorectal cancer via the PTEN-AKT axis
Q38189403Cellular Response to Ionizing Radiation: A MicroRNA Story
Q35651246Cellular microRNA miR-26a suppresses replication of porcine reproductive and respiratory syndrome virus by activating innate antiviral immunity
Q41615120Chemical Inhibitors and microRNAs (miRNA) Targeting the Mammalian Target of Rapamycin (mTOR) Pathway: Potential for Novel Anticancer Therapeutics
Q45673083Circadian gene Clock contributes to cell proliferation and migration of glioma and is directly regulated by tumor-suppressive miR-124.
Q42039758Circulating Plasma microRNAs can differentiate Human Sepsis and Systemic Inflammatory Response Syndrome (SIRS).
Q38776396Circulating microRNAs in acute and chronic exercise: more than mere biomarkers
Q34508976Clinical development of phosphatidylinositol 3-kinase inhibitors for cancer treatment
Q39160992Co-inhibitory blockade while preserving tolerance: checkpoint inhibitors for glioblastoma
Q24629589Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs
Q50420455Cohesive Regulation of Neural Progenitor Development by microRNA miR-26, Its Host Gene Ctdsp and Target Gene Emx2 in the Mouse Embryonic Cerebral Cortex.
Q48470503Comparative genomic and proteomic analysis of high grade glioma primary cultures and matched tumor in situ
Q64253022Comparison of the Transcriptomes and Proteomes of Serum Exosomes from Marek's Disease Virus-Vaccinated and Protected and Lymphoma-Bearing Chickens
Q41136585Comprehensive analysis of microRNA expression profile in malignant glioma tissues
Q26996848Connecting the dots between tau dysfunction and neurodegeneration
Q39177304Cooperative control of tumor suppressor genes by a network of oncogenic microRNAs
Q34416068Costimulation-dependent expression of microRNA-214 increases the ability of T cells to proliferate by targeting Pten.
Q38259629Critical Role of c-Myc in Acute Myeloid Leukemia Involving Direct Regulation of miR-26a and Histone Methyltransferase EZH2.
Q38034755Current Progress on Understanding MicroRNAs in Glioblastoma Multiforme
Q38102611Current progress for the use of miRNAs in glioblastoma treatment
Q42115145Decoding the cancer stem cell hypothesis in glioblastoma
Q64067528Deregulated MicroRNA Signature Following Glioblastoma Irradiation
Q38057886Deregulated microRNAs identified in isolated glioblastoma stem cells: an overview.
Q28534050Developmental and activity-dependent miRNA expression profiling in primary hippocampal neuron cultures
Q92253114Discovery of 5-Signature Predicting Survival of Patients with Lower-Grade Glioma
Q92840399Downregulation of serum miR-26a predicts poor clinical outcome of papillary thyroid carcinoma
Q37961805Epigenetic architecture and miRNA: reciprocal regulators.
Q91712007Estrogen Reverses HDAC Inhibitor-Mediated Repression of Aicda and Class-Switching in Antibody and Autoantibody Responses by Downregulation of miR-26a
Q45613688Evaluation of miR-362 Expression in Astrocytoma of Human Brain Tumors
Q64259621Exploration of miRNA and mRNA Profiles in Fresh and Frozen-Thawed Boar Sperm by Transcriptome and Small RNA Sequencing
Q48090086Expression level of miRNAs on chromosome 14q32.31 region correlates with tumor aggressiveness and survival of glioblastoma patients.
Q41135067Expression of 19 microRNAs in glioblastoma and comparison with other brain neoplasia of grades I-III.
Q35043317Expression of microRNAs is essential for arterial myogenic tone and pressure-induced activation of the PI3-kinase/Akt pathway.
Q53078040Expression, regulation and roles of miR-26a and MEG3 in tongue squamous cell carcinoma.
Q26797287Focus on PTEN Regulation
Q35010133Four microRNAs promote prostate cell proliferation with regulation of PTEN and its downstream signals in vitro
Q28267167Functional screen analysis reveals miR-26b and miR-128 as central regulators of pituitary somatomammotrophic tumor growth through activation of the PTEN-AKT pathway
Q34203950Genetic alterations in microRNAs in medulloblastomas
Q37955107Genetic alterations of PTEN in human melanoma
Q48089491Genome-wide expression profiling identifies deregulated miRNAs in malignant astrocytoma
Q34257360Genome-wide profiling identified a set of miRNAs that are differentially expressed in glioblastoma stem cells and normal neural stem cells.
Q38606228Genomic integrity and the ageing brain
Q38207605Glioblastoma stem cells: Molecular characteristics and therapeutic implications
Q39005215Glioblastoma: exosome and microRNA as novel diagnosis biomarkers.
Q38460865Glioblastoma: pathology, molecular mechanisms and markers
Q24631473Glioma-associated cytomegalovirus mediates subversion of the monocyte lineage to a tumor propagating phenotype
Q34115364HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN/AKT/mTOR signaling pathway
Q92921699High Mobility Group A (HMGA): Chromatin Nodes Controlled by a Knotty miRNA Network
Q58719119High miR-718 Suppresses Phosphatase and Tensin Homolog (PTEN) Expression and Correlates to Unfavorable Prognosis in Gastric Cancer
Q37492187High-throughput microRNA profiling of pediatric high-grade gliomas.
Q37065678How genetically engineered mouse tumor models provide insights into human cancers
Q34140925Human traumatic brain injury alters plasma microRNA levels.
Q35319936Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway
Q37269137Hypoxia-regulated gene expression explains differences between melanoma cell line-derived xenografts and patient-derived xenografts.
Q47575408Identification and Characterization of Metastatic Factors by Gene Transfer into the Novel RIP-Tag; RIP-tva Murine Model
Q38432744Identification and functional analysis of the risk microRNAs associated with cerebral low-grade glioma prognosis
Q92366540Identification and validation of mRNA 3'untranslated regions of DNMT3B and TET3 as novel competing endogenous RNAs of the tumor suppressor PTEN
Q36733776Identification of MLL-fusion/MYC⊣miR-26⊣TET1 signaling circuit in MLL-rearranged leukemia
Q36295318Identification of global alteration of translational regulation in glioma in vivo
Q37366610Improved Adeno-associated Viral Gene Transfer to Murine Glioma.
Q34030947Increased prevalence of eosinophilic gastrointestinal disorders in pediatric PTEN hamartoma tumor syndromes
Q39692548Integrative Analysis of mRNA, microRNA, and Protein Correlates of Relative Cerebral Blood Volume Values in GBM Reveals the Role for Modulators of Angiogenesis and Tumor Proliferation.
Q33719798Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship
Q36552755Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients
Q26770381Interplay Between Metabolism and Oncogenic Process: Role of microRNAs
Q34393758Intratumoral mediated immunosuppression is prognostic in genetically engineered murine models of glioma and correlates to immunotherapeutic responses
Q24608490Intronic miR-26b controls neuronal differentiation by repressing its host transcript, ctdsp2
Q39615360Involvement of miR-21 in resistance to daunorubicin by regulating PTEN expression in the leukaemia K562 cell line
Q39007424KAP regulates ROCK2 and Cdk2 in an RNA-activated glioblastoma invasion pathway
Q38745227KH-type splicing regulatory protein (KHSRP) contributes to tumorigenesis by promoting miR-26a maturation in small cell lung cancer
Q61800908Label-free Quantitative Analysis of Protein Expression Alterations in miR-26a-Knockout HeLa Cells using SWATH-MS Technology
Q64055134Limits Muscle Wasting and Cardiac Fibrosis through Exosome-Mediated microRNA Transfer in Chronic Kidney Disease
Q37636621Loss of MYC and E-box3 binding contributes to defective MYC-mediated transcriptional suppression of human MC-let-7a-1~let-7d in glioblastoma
Q33744534Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies
Q34547703Metformin inhibits cell growth by upregulating microRNA-26a in renal cancer cells.
Q35627069MiR-138 Suppresses Cell Proliferation by Targeting Bag-1 in Gallbladder Carcinoma
Q36757035MiR-26a Rescues Bone Regeneration Deficiency of Mesenchymal Stem Cells Derived From Osteoporotic Mice
Q38750019MiR-26a and miR-138 block the G1/S transition by targeting the cell cycle regulating network in prostate cancer cells.
Q37046835MiR-26a and miR-144 inhibit proliferation and metastasis of esophageal squamous cell cancer by inhibiting cyclooxygenase-2.
Q38706042MiR-26a downregulates retinoblastoma in colorectal cancer.
Q36080088MiR-26a enhances autophagy to protect against ethanol-induced acute liver injury.
Q45012413MiR-26a enhances the radiosensitivity of glioblastoma multiforme cells through targeting of ataxia-telangiectasia mutated
Q34764211MiR-26a inhibits proliferation and migration of breast cancer through repression of MCL-1
Q37505913MiR-26a promotes ovarian cancer proliferation and tumorigenesis
Q92917167MiR-26a-5p enhances cells proliferation, invasion, and apoptosis resistance of fibroblast-like synoviocytes in rheumatoid arthritis by regulating PTEN/PI3K/AKT pathway
Q37261417MiR-26b, upregulated in Alzheimer's disease, activates cell cycle entry, tau-phosphorylation, and apoptosis in postmitotic neurons
Q39519803MiRNA expression profiling in human gliomas: upregulated miR-363 increases cell survival and proliferation
Q89880080Micro RNA Molecules as Modulators of Treatment Resistance, Immune Checkpoints Controllers and Sensitive Biomarkers in Glioblastoma Multiforme
Q37981156MicroRNA Control of Invasion and Metastasis Pathways
Q41208796MicroRNA Regulation of Glycolytic Metabolism in Glioblastoma.
Q53137197MicroRNA and cancer.
Q37706077MicroRNA control of signal transduction
Q34409620MicroRNA expression signatures determine prognosis and survival in glioblastoma multiforme--a systematic overview.
Q37420580MicroRNA in Human Glioma
Q37619633MicroRNA profiling of low-grade glial and glioneuronal tumors shows an independent role for cluster 14q32.31 member miR-487b
Q34793627MicroRNA regulation of IFN-beta protein expression: rapid and sensitive modulation of the innate immune response
Q34185623MicroRNA sequence and expression analysis in breast tumors by deep sequencing
Q54284943MicroRNA-144 promotes cell proliferation, migration and invasion in nasopharyngeal carcinoma through repression of PTEN.
Q38731400MicroRNA-152 Targets Phosphatase and Tensin Homolog to Inhibit Apoptosis and Promote Cell Migration of Nasopharyngeal Carcinoma Cells
Q39196866MicroRNA-153 is tumor suppressive in glioblastoma stem cells.
Q38715688MicroRNA-153 regulates glutamine metabolism in glioblastoma through targeting glutaminase
Q48381555MicroRNA-15a down-regulation is associated with adverse prognosis in human glioma
Q36202394MicroRNA-17-5p induces drug resistance and invasion of ovarian carcinoma cells by targeting PTEN signaling
Q24633326MicroRNA-182-5p targets a network of genes involved in DNA repair
Q34436329MicroRNA-20b promotes cell growth of breast cancer cells partly via targeting phosphatase and tensin homologue (PTEN).
Q64233019MicroRNA-20b promotes proliferation of H22 hepatocellular carcinoma cells by targeting PTEN
Q35032496MicroRNA-26a inhibits angiogenesis by down-regulating VEGFA through the PIK3C2α/Akt/HIF-1α pathway in hepatocellular carcinoma
Q41856145MicroRNA-26a inhibits osteosarcoma cell proliferation by targeting IGF-1.
Q35145305MicroRNA-26a inhibits proliferation by targeting high mobility group AT-hook 1 in breast cancer
Q24624403MicroRNA-26a is a novel regulator of vascular smooth muscle cell function
Q35273569MicroRNA-26a promotes anoikis in human hepatocellular carcinoma cells by targeting alpha5 integrin
Q39123359MicroRNA-26a promotes tumor growth and angiogenesis in glioma by directly targeting prohibitin
Q33807718MicroRNA-26a regulates glucose metabolism by direct targeting PDHX in colorectal cancer cells
Q47616223MicroRNA-26a suppresses angiogenesis in human hepatocellular carcinoma by targeting hepatocyte growth factor-cMet pathway
Q36433424MicroRNA-26a suppresses epithelial-mesenchymal transition in human hepatocellular carcinoma by repressing enhancer of zeste homolog 2.
Q46255425MicroRNA-26a suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting interleukin-6-Stat3 pathway
Q42290877MicroRNA-26a targets MAPK6 to inhibit smooth muscle cell proliferation and vein graft neointimal hyperplasia
Q93185200MicroRNA-26a-5p inhibits proliferation, invasion and metastasis by repressing the expression of Wnt5a in papillary thyroid carcinoma
Q40647567MicroRNA-26a-mediated regulation of interleukin-2 expression in transformed avian lymphocyte lines.
Q38714023MicroRNA-26a/cyclin-dependent kinase 5 axis controls proliferation, apoptosis and in vivo tumor growth of diffuse large B-cell lymphoma cell lines
Q36304803MicroRNA-26b Modulates the NF-κB Pathway in Alveolar Macrophages by Regulating PTEN.
Q61443739MicroRNA-29a activates a multi-component growth and invasion program in glioblastoma
Q33843200MicroRNA-382 induced by HIF-1α is an angiogenic miR targeting the tumor suppressor phosphatase and tensin homolog
Q89475347MicroRNA-498 promotes proliferation and migration by targeting the tumor suppressor PTEN in breast cancer cells
Q46190130MicroRNA-target cross-talks: Key players in glioblastoma multiforme
Q55460934MicroRNA142-3p promotes tumor-initiating and radioresistant properties in malignant pediatric brain tumors.
Q36602853MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid Malignancies
Q37857375MicroRNAs and glioblastoma: roles in core signalling pathways and potential clinical implications
Q37897499MicroRNAs as regulators of neural stem cell-related pathways in glioblastoma multiforme
Q35832148MicroRNAs in apoptosis, autophagy and necroptosis
Q26865287MicroRNAs in cancer: glioblastoma and glioblastoma cancer stem cells
Q34760006MicroRNAs in cardiac disease
Q26747273MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics
Q34325959MicroRNAs in human cancer
Q39446959MicroRNAs in mucosal inflammation.
Q37974078MicroRNAs in neural cell development and brain diseases
Q27027517MicroRNAs in stress signaling and human disease
Q38097384MicroRNAs involved in chemo- and radioresistance of high-grade gliomas
Q37917655MicroRNAs involved in the EGFR/PTEN/AKT pathway in gliomas
Q35388050MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals
Q28657834MicroRNAs: history, biogenesis, and their evolving role in animal development and disease
Q35135542MicroRNAs: new players in IBD.
Q27027998MicroRNAs: promising new antiangiogenic targets in cancer
Q37833881MicroRNAs: redefining mechanisms in cardiac disease
Q64234430Micromanaging aerobic respiration and glycolysis in cancer cells
Q36272539Mir-21-Sox2 Axis Delineates Glioblastoma Subtypes with Prognostic Impact
Q38280833Modeling glands with PTEN deficient cells and microscopic methods for assessing PTEN loss: endometrial cancer as a model
Q34469322Modulation of the osteosarcoma expression phenotype by microRNAs
Q38465854Molecular targets in glioblastoma
Q34083282Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma
Q92906114Multifaceted Regulation of PTEN Subcellular Distributions and Biological Functions
Q39000847Mutant IDH1 inhibits PI3K/Akt signaling in human glioma.
Q35640345Myc enforces overexpression of EZH2 in early prostatic neoplasia via transcriptional and post-transcriptional mechanisms
Q37614231NPM-ALK up-regulates iNOS expression through a STAT3/microRNA-26a-dependent mechanism.
Q38604713New Treatment Opportunities in Phosphatase and Tensin Homolog (PTEN)-Deficient Tumors: Focus on PTEN/Focal Adhesion Kinase Pathway
Q26823718Noncoding RNA in oncogenesis: a new era of identifying key players
Q26864697Noncoding RNAs in DNA repair and genome integrity
Q30413140Novel anti-apoptotic microRNAs 582-5p and 363 promote human glioblastoma stem cell survival via direct inhibition of caspase 3, caspase 9, and Bim.
Q33579323Oncogene interactions are required for glioma development and progression as revealed by a tissue specific transgenic mouse model
Q36778838Oncogenic B-Raf signaling in melanoma cells controls a network of microRNAs with combinatorial functions
Q59123158OncomiR-10b hijacks the small molecule inhibitor linifanib in human cancers
Q36898111Overexpression of miR-26a-2 in human liposarcoma is correlated with poor patient survival
Q36375834PDGF-B-mediated downregulation of miR-21: new insights into PDGF signaling in glioblastoma
Q45314383PI3K/AKT Signaling in Cancer
Q39584693PIK3CA mutation, but not PTEN loss of function, determines the sensitivity of breast cancer cells to mTOR inhibitory drugs
Q45314387PTEN Loss of Function in Cancer
Q45318299PTEN Regulation
Q36452913PTEN at a glance
Q53601178PTEN gene is infrequently hypermethylated in human esophageal squamous cell carcinoma.
Q35056451PTEN is a negative regulator of NK cell cytolytic function.
Q37856722PTEN loss in the continuum of common cancers, rare syndromes and mouse models.
Q50299118PTEN mRNA translation is negatively regulated by microRNAs
Q50290154PTEN mRNA translation negatively regulated by microRNAs
Q38738670PTEN protein loss by immunostaining: analytic validation and prognostic indicator for a high risk surgical cohort of prostate cancer patients
Q27011088PTEN regulation of ERK1/2 signaling in cancer
Q28295895Pathologically decreased miR-26a antagonizes apoptosis and facilitates carcinogenesis by targeting MTDH and EZH2 in breast cancer
Q58766575Phenotypic miRNA Screen Identifies miR-26b to Promote the Growth and Survival of Endothelial Cells
Q47127377Plasma MicroRNA-21, 26a, and 29a-3p as Predictive Markers for Treatment Response Following Transarterial Chemoembolization in Patients with Hepatocellular Carcinoma.
Q36504138Polymorphisms in pre-miRNA genes and cooking oil fume exposure as well as their interaction on the risk of lung cancer in a Chinese nonsmoking female population
Q59333218Potential Epigenetic-Based Therapeutic Targets for Glioma
Q55463671Potential role of miRNAs and their inhibitors in glioma treatment.
Q34159409Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases.
Q48473937Profile of microRNA expression in brain tumors of different malignancy
Q64116760Prognostic Significance of MicroRNAs in Glioma: A Systematic Review and Meta-Analysis
Q34238901Prognostic significance of miR-205 in endometrial cancer
Q37584292Prospects of miRNA-based therapy for pancreatic cancer
Q64245074Protein Phosphatases-A Touchy Enemy in the Battle Against Glioblastomas: A Review
Q37638344Protein tyrosine phosphatases in glioma biology
Q24632928Recent advances in the molecular understanding of glioblastoma
Q34017894Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene
Q33732748Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486
Q45318301Regulation of PTEN mRNA translation
Q35140496Relationships between PTEN gene mutations and prognosis in glioma: a meta-analysis
Q36152814Retracted: MicroRNA-20b (miR-20b) Promotes the Proliferation, Migration, Invasion, and Tumorigenicity in Esophageal Cancer Cells via the Regulation of Phosphatase and Tensin Homologue Expression
Q34825705Retracted: miR-26a and its Target CKS2 Modulate Cell Growth and Tumorigenesis of Papillary Thyroid Carcinoma
Q37617262Role of 3'-untranslated region translational control in cancer development, diagnostics and treatment
Q36797902Role of MicroRNAs in Malignant Glioma
Q34989089Role of miR-10b in breast cancer metastasis
Q33559304Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives.
Q38027227Role of microRNAs in gliomagenesis: targeting miRNAs in glioblastoma multiforme therapy
Q59798408SWIM tool application to expression data of glioblastoma stem-like cell lines, corresponding primary tumors and conventional glioma cell lines
Q36179166Signal transducer and activator of transcription 3 promotes angiogenesis and drives malignant progression in glioma
Q34676929Simultaneous miRNA and mRNA transcriptome profiling of human myoblasts reveals a novel set of myogenic differentiation-associated miRNAs and their target genes
Q38237392Stem cell delivery of therapies for brain disorders.
Q83381970Stromal miR-320 keeps an oncogenic secretome in check
Q42289696Sustained expression of miR-26a promotes chromosomal instability and tumorigenesis through regulation of CHFR.
Q36866612TET3 inhibits TGF-β1-induced epithelial-mesenchymal transition by demethylating miR-30d precursor gene in ovarian cancer cells
Q45743838Targeted therapy in sarcomas: mammalian target of rapamycin inhibitors from bench to bedside.
Q28287476Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation
Q38584755Targeting MicroRNAs in Prevention and Treatment of Neurodegenerative Disorders.
Q37736255Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma
Q37210093The Antitumor Effect of Metformin Is Mediated by miR-26a in Breast Cancer
Q99591126The Role of Exosomes in Stemness and Neurodegenerative Diseases-Chemoresistant-Cancer Therapeutics and Phytochemicals
Q36268915The expression of PTEN is associated with improved prognosis in patients with ampullary adenocarcinoma after pancreaticoduodenectomy
Q37344777The locus of microRNA-10b: a critical target for breast cancer insurgence and dissemination
Q35014682The loss of miR-26a-mediated post-transcriptional regulation of cyclin E2 in pancreatic cancer cell proliferation and decreased patient survival
Q55463784The many functions of microRNAs in glioblastoma.
Q34657471The miR-221/222 cluster, miR-10b and miR-92a are highly upregulated in metastatic minimally invasive follicular thyroid carcinoma
Q90169615The miR-26a/AP-2α/Nanog signaling axis mediates stem cell self-renewal and temozolomide resistance in glioma
Q30417554The miR-99 family regulates the DNA damage response through its target SNF2H
Q33728363The microRNA and messengerRNA profile of the RNA-induced silencing complex in human primary astrocyte and astrocytoma cells
Q37082176The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis
Q36898251The microRNA-148/152 family: multi-faceted players
Q45901790The microRNA-21/PTEN pathway regulates the sensitivity of HER2-positive gastric cancer cells to trastuzumab.
Q38155656The molecular landscape of diffuse glioma and prospects for biomarker development
Q24629056The role of miR-26 in tumors and normal tissues (Review)
Q38796729The role of microRNA-26a in human cancer progression and clinical application
Q37601781The role of microRNAs in endometriosis and associated reproductive conditions
Q30428370The role of microRNAs in glioma initiation and progression
Q33937611The top cited articles on glioma stem cells in Web of Science
Q33744491The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas
Q35876143Therapy-, gender- and race-specific microRNA markers, target genes and networks related to glioblastoma recurrence and survival.
Q34590225Tumor suppression by miR-26 overrides potential oncogenic activity in intestinal tumorigenesis
Q34518462Tumor-suppressive miR148a is silenced by CpG island hypermethylation in IDH1-mutant gliomas.
Q37269315Twist1-related miR-26b-5p suppresses epithelial-mesenchymal transition, migration and invasion by targeting SMAD1 in hepatocellular carcinoma
Q33784406Unregulated miR-96 induces cell proliferation in human breast cancer by downregulating transcriptional factor FOXO3a
Q34998307Up-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancer
Q35993546Utility of Serum miR-125b as a Diagnostic and Prognostic Indicator and Its Alliance with a Panel of Tumor Suppressor Genes in Epithelial Ovarian Cancer
Q34014258Walking the interactome to identify human miRNA-disease associations through the functional link between miRNA targets and disease genes
Q49790324[MicroRNA-26a and Tumor].
Q36300857cAMP response element-binding protein promotes gliomagenesis by modulating the expression of oncogenic microRNA-23a
Q89537480miR-1269b Drives Cisplatin Resistance of Human Non-Small Cell Lung Cancer via Modulating the PTEN/PI3K/AKT Signaling Pathway
Q46272050miR-148a-3p Mediates Notch Signaling to Promote the Differentiation and M1 Activation of Macrophages
Q89511641miR-20b and miR-451a Are Involved in Gastric Carcinogenesis through the PI3K/AKT/mTOR Signaling Pathway: Data from Gastric Cancer Patients, Cell Lines and Ins-Gas Mouse Model
Q47380679miR-20b promotes cellular proliferation and migration by directly regulating phosphatase and tensin homolog in prostate cancer
Q21091130miR-22 forms a regulatory loop in PTEN/AKT pathway and modulates signaling kinetics
Q50290153miR-26A microRNAs bind PTEN mRNA
Q39135735miR-26a inhibits proliferation and motility in bladder cancer by targeting HMGA1.
Q48344914miR-26a promoted endometrial epithelium cells (EECs) proliferation and induced stromal cells (ESCs) apoptosis via the PTEN-PI3K/AKT pathway in dairy goats
Q92761624miR-26a promotes hepatocellular carcinoma invasion and metastasis by inhibiting PTEN and inhibits cell growth by repressing EZH2
Q34981594miR-26a suppresses tumor growth and metastasis by targeting FGF9 in gastric cancer
Q92648780miR-3691-5p promotes hepatocellular carcinoma cell migration and invasion through activating PI3K/Akt signaling by targeting PTEN
Q38962553miR-372 regulates glioma cell proliferation and invasion by directly targeting PHLPP2.
Q40328958miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN).
Q42182365miR26a modulates Th17/T reg balance in the EAE model of multiple sclerosis by targeting IL6.
Q39254996miRNA Regulation in Gliomas: Usual Suspects in Glial Tumorigenesis and Evolving Clinical Applications
Q24598174miRNA and vascular cell movement
Q26781836miRNA interventions serve as 'magic bullets' in the reversal of glioblastoma hallmarks
Q38824458miRNA-182 and the regulation of the glioblastoma phenotype - toward miRNA-based precision therapeutics
Q42563520miRNA-mediated immune regulation and immunotherapeutic potential in glioblastoma
Q34243937miRNAs expression analysis in paired fresh/frozen and dissected formalin fixed and paraffin embedded glioblastoma using real-time pCR.
Q24628889miRNAs in human cancer
Q35684366microRNA-26a suppresses recruitment of macrophages by down-regulating macrophage colony-stimulating factor expression through the PI3K/Akt pathway in hepatocellular carcinoma.
Q89720471microRNAs Orchestrate Pathophysiology of Breast Cancer Brain Metastasis: Advances in Therapy
Q27693891microRNAs and RNA-binding proteins: a complex network of interactions and reciprocal regulations in cancer
Q37592046microRNAs in gliomas: small regulators of a big problem

Search more.