Thomas Tuschl

German biochemist

DBpedia resource is: http://dbpedia.org/resource/Thomas_Tuschl

Abstract is: Thomas Tuschl (born June 1, 1966) is a German biochemist and molecular biologist, known for his research on RNA.

Born 1966-06-01 in Altdorf bei Nürnberg (Q435295)

Thomas Tuschl is …
instance of (P31):
humanQ5

External links are
P2381Academic Tree ID51407
P8168FactGrid item IDQ889405
P646Freebase ID/m/04csm4t
P227GND ID115043187
P1960Google Scholar author IDDBU5a2QAAAAJ
P269IdRef ID111860172
P213ISNI000000011766045X
P10299Leopoldina member ID (new)thomas-tuschl
P3413Leopoldina member ID (superseded)1426
P244Library of Congress authority IDn2006183349
P1284Munzinger person ID00000025679
P1207NUKAT IDn2007153276
P3368Prabook ID1784048
P214VIAF ID60983477
P10832WorldCat Entities IDE39PBJvcWQwxDvxKfFQqj6MkjC

P166award receivedKlung Wilhelmy Science AwardQ876919
Ernst Schering PrizeQ1360050
Max Delbrück MedalQ1912013
Meyenburg PrizeQ1926301
Karl Heinz Beckurts AwardQ29841295
Ernst Jung Prize for MedicineQ29886440
Newcomb Cleveland PrizeQ7017608
P27country of citizenshipGermanyQ183
P108employerThe Rockefeller UniversityQ270272
P734family nameTuschlQ37084843
TuschlQ37084843
TuschlQ37084843
P735given nameThomasQ16428906
ThomasQ16428906
P1412languages spoken, written or signedGermanQ188
P463member ofGerman Academy of Sciences LeopoldinaQ543804
P1559name in native languageThomas Tuschl
P106occupationuniversity teacherQ1622272
biochemistQ2919046
molecular biologistQ15839206
P21sex or gendermaleQ6581097

Reverse relations

author (P50)
Q57009065Q57009065
Q37072123A Drosophila pasha mutant distinguishes the canonical microRNA and mirtron pathways
Q58283908A census of human RNA-binding proteins
Q36944883A comprehensive analysis of the effects of the deaminase AID on the transcriptome and methylome of activated B cells
Q35853457A genome-wide view of the expression and processing patterns of Thermus thermophilus HB8 CRISPR RNAs
Q24644709A mammalian microRNA expression atlas based on small RNA library sequencing
Q28505738A novel class of small RNAs bind to MILI protein in mouse testes
Q28292726A pancreatic islet-specific microRNA regulates insulin secretion
Q36407767A potential protein-RNA recognition event along the RISC-loading pathway from the structure of A. aeolicus Argonaute with externally bound siRNA.
Q28352546A ribozyme selected from variants of U6 snRNA promotes 2',5'-branch formation
Q34249905A role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticity
Q34129012A selective microRNA-based strategy inhibits restenosis while preserving endothelial function
Q27730782A three-dimensional model for the hammerhead ribozyme based on fluorescence measurements
Q24540187A uniform system for microRNA annotation
Q35952724AUF1 promotes let-7b loading on Argonaute 2.
Q37426569Absolute quantification of microRNAs by using a universal reference
Q40412377Activity of hammerhead ribozymes containing non-nucleotidic linkers
Q34249693An image-based biosensor assay strategy to screen for modulators of the microRNA 21 biogenesis pathway
Q29616541Analysis of gene function in somatic mammalian cells using small interfering RNAs
Q49213989Analysis of the miRNA targetome in EBV-infected B cells
Q28259235Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development
Q58283916Barcoded cDNA Libraries for miRNA Profiling by Next-Generation Sequencing
Q36429533Barcoded cDNA library preparation for small RNA profiling by next-generation sequencing
Q35238345Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA.
Q36103092Biochemical isolation of Argonaute protein complexes by Ago-APP
Q34353154Bioinformatic analysis of barcoded cDNA libraries for small RNA profiling by next-generation sequencing
Q35897976Cell and Microvesicle Urine microRNA Deep Sequencing Profiles from Healthy Individuals: Observations with Potential Impact on Biomarker Studies
Q24317564Cellular cofactors affecting hepatitis C virus infection and replication
Q33873827Characterization of small RNAs in Aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB.
Q47972624Characterizing Expression and Processing of Precursor and Mature Human tRNAs by Hydro-tRNAseq and PAR-CLIP.
Q24524119Clustering and conservation patterns of human microRNAs
Q28505594Co-repressor CBFA2T2 regulates pluripotency and germline development
Q35048500Combined characterization of microRNA and mRNA profiles delineates early differentiation pathways of CD133+ and CD34+ hematopoietic stem and progenitor cells
Q34002423Comparative RNA-sequencing analysis of myocardial and circulating small RNAs in human heart failure and their utility as biomarkers
Q36693002Comprehensive profiling of circulating microRNA via small RNA sequencing of cDNA libraries reveals biomarker potential and limitations
Q24816035Correction: Human MicroRNA Targets
Q36399157Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage
Q28766178Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense
Q27678007Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
Q37062042DGCR8-dependent microRNA biogenesis is essential for skin development
Q41016268DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs
Q38988230Deep MicroRNA sequencing reveals downregulation of miR-29a in neuroblastoma central nervous system metastasis
Q38749559Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma
Q33860348Deep sequencing of small RNAs specifically associated with Arabidopsis AGO1 and AGO4 uncovers new AGO functions
Q45085238Design of hammerhead ribozymes for the inhibition of gene expression ex vivo by exogenous application.
Q37218797Differential regulation of mature and precursor microRNA expression by NMDA and metabotropic glutamate receptor activation during LTP in the adult dentate gyrus in vivo
Q35816449Discovery and Characterization of piRNAs in the Human Fetal Ovary
Q27860926Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
Q28255230Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau
Q34777377ELAVL1 modulates transcriptome-wide miRNA binding in murine macrophages
Q35159151Efficient differentiation of steroidogenic and germ-like cells from epigenetically-related iPSCs derived from ovarian granulosa cells
Q35131625Efficient solid-phase synthesis of pppRNA by using product-specific labeling
Q24656088Elevated expression of the miR-17-92 polycistron and miR-21 in hepadnavirus-associated hepatocellular carcinoma contributes to the malignant phenotype
Q39941477Empirical insights into the stochasticity of small RNA sequencing
Q40481959Endogenous MHC class II processing of a viral nuclear antigen after autophagy.
Q24296957Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
Q26991754Evolutionary conservation and expression of human RNA-binding proteins and their role in human genetic disease
Q28117931FMRP targets distinct mRNA sequence elements to regulate protein expression
Q33740977FOXO1 is an essential regulator of pluripotency in human embryonic stem cells
Q28365532Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
Q28706086Genome-wide annotation and analysis of zebra finch microRNA repertoire reveal sex-biased expression
Q42362388Genome-wide identification of miRNA targets by PAR-CLIP.
Q35494003Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response
Q33741987Global target mRNA specification and regulation by the RNA-binding protein ZFP36.
Q36444559Hammerhead ribozymes: importance of stem-loop II for activity
Q24299641Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs
Q21563637Human MicroRNA targets
Q33223084Identification and characterization of small RNAs involved in RNA silencing
Q27023093Identification of RNA-protein interaction networks using PAR-CLIP
Q24812490Identification of clustered microRNAs using an ab initio prediction method
Q33741864Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets
Q40756849Identification of essential genes in cultured mammalian cells using small interfering RNAs.
Q41889151Identification of mRNAs bound and regulated by human LIN28 proteins and molecular requirements for RNA recognition
Q24609501Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing
Q24295156Identification of novel argonaute-associated proteins
Q27860917Identification of novel genes coding for small expressed RNAs
Q33967961Identification of the RNA recognition element of the RBPMS family of RNA-binding proteins and their transcriptome-wide mRNA targets
Q27860892Identification of tissue-specific microRNAs from mouse
Q28259309Identification of virus-encoded microRNAs
Q38314474Importance of exocyclic base functional groups of central core guanosines for hammerhead ribozyme activity
Q35031404In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA.
Q35562869Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability
Q37608509Kruppel-like factor 15 is a critical regulator of cardiac lipid metabolism
Q33742097Learning the language of post-transcriptional gene regulation
Q34917408Mammalian miRNA curation through next-generation sequencing
Q28282560Mechanisms of gene silencing by double-stranded RNA
Q34185623MicroRNA sequence and expression analysis in breast tumors by deep sequencing
Q34468508MicroRNA sequence profiles of human kidney allografts with or without tubulointerstitial fibrosis
Q24806738MicroRNA targets in Drosophila
Q24653222MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase
Q28511032MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
Q35228513MicroRNA-21 in glomerular injury
Q47037318MicroRNA-24 regulates vascularity after myocardial infarction
Q36734930MicroRNA-mediated down-regulation of PRDM1/Blimp-1 in Hodgkin/Reed-Sternberg cells: a potential pathogenetic lesion in Hodgkin lymphomas
Q33809305MicroRNAs MiR-17, MiR-20a, and MiR-106b act in concert to modulate E2F activity on cell cycle arrest during neuronal lineage differentiation of USSC.
Q34325959MicroRNAs in human cancer
Q34590603MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood
Q36990752Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs
Q38633387Mu opioid receptor knockdown in the substantia nigra/ventral tegmental area by synthetic small interfering RNA blocks the rewarding and locomotor effects of heroin
Q34604891Multi-disciplinary methods to define RNA-protein interactions and regulatory networks
Q34348056Multicolor microRNA FISH effectively differentiates tumor types
Q27667762Multimeric assembly and biochemical characterization of the Trax–translin endonuclease complex
Q35023450Multiplexed miRNA fluorescence in situ hybridization for formalin-fixed paraffin-embedded tissues
Q43156623New insights in the mechanism of microRNA-mediated target repression
Q24540176New microRNAs from mouse and human
Q41867966Novel MIR143-NOTCH fusions in benign and malignant glomus tumors
Q27657724Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes
Q40398102Oligonucleotide duplexes containing 2'-amino-2'-deoxycytidines: thermal stability and chemical reactivity
Q36575382On the art of identifying effective and specific siRNAs
Q38986620Optimization of PAR-CLIP for transcriptome-wide identification of binding sites of RNA-binding proteins
Q34269905PAR-CLIP (Photoactivatable Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation): a step-by-step protocol to the transcriptome-wide identification of binding sites of RNA-binding proteins
Q34919601PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity
Q47298405PAR-CLIP for Discovering Target Sites of RNA-Binding Proteins
Q28288331PAR-CliP--a method to identify transcriptome-wide the binding sites of RNA binding proteins
Q47556307Premature recruitment of oocyte pool and increased mTOR activity in Fmr1 knockout mice and reversal of phenotype with rapamycin
Q41831670Probing RNA tertiary structure: interhelical crosslinking of the hammerhead ribozyme
Q36341552Quantitative mass spectrometry and PAR-CLIP to identify RNA-protein interactions
Q57234164Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia
Q40840939RISC is a 5' phosphomonoester-producing RNA endonuclease
Q40428287RNA cleavage by small catalytic RNAs
Q33957221RNA interference and small interfering RNAs
Q33205315RNA interference by osmotic lysis of pinosomes: liposome-independent transfection of siRNAs into mammalian cells
Q27860764RNA interference is mediated by 21- and 22-nucleotide RNAs
Q59036090RNA sets the standard
Q39603230RNA targets of wild-type and mutant FET family proteins
Q33966769RNA-ligase-dependent biases in miRNA representation in deep-sequenced small RNA cDNA libraries
Q29547713RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
Q39099327Rapid creation of stable mammalian cell lines for regulated expression of proteins using the Gateway® recombination cloning technology and Flp-In T-REx® lines
Q24310706Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus
Q36059543Repeat-associated siRNAs cause chromatin silencing of retrotransposons in the Drosophila melanogaster germline
Q36647195Reprogramming of the microRNA transcriptome mediates resistance to rapamycin
Q32066109Selection in vitro of novel ribozymes from a partially randomized U2 and U6 snRNA library
Q40640189Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing
Q24537549Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing
Q27860891Silencing of microRNAs in vivo with 'antagomirs'
Q38963482Simultaneous detection of the subcellular localization of RNAs and proteins in cultured cells by combined multicolor RNA-FISH and IF.
Q28201784Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
Q33938849Small RNA sequencing and functional characterization reveals MicroRNA-143 tumor suppressor activity in liposarcoma
Q35679433Small interfering RNAs: a revolutionary tool for the analysis of gene function and gene therapy
Q40206416Specific RNAi mediated gene knockdown in zebrafish cell lines
Q35837407Specificity, duplex degradation and subcellular localization of antagomirs
Q36400708Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity
Q27662820Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I
Q33986097Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein
Q29347517Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS
Q36399186Structural biology of RNA silencing and its functional implications
Q27653175Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex
Q27651827Structure of the guide-strand-containing argonaute silencing complex
Q27679344Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA
Q27677855Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites
Q41627991Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes
Q35210341Targeted mRNA degradation by double-stranded RNA in vitro
Q42601425The Conserved RNA Exonuclease Rexo5 Is Required for 3' End Maturation of 28S rRNA, 5S rRNA, and snoRNAs
Q40975929The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs
Q24657924The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo
Q37315134The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation
Q50074822The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression.
Q24529122The developmental miRNA profiles of zebrafish as determined by small RNA cloning
Q37089444The growing catalog of small RNAs and their association with distinct Argonaute/Piwi family members
Q24293219The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome
Q28297566The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis
Q37286651The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation
Q28201894The small RNA profile during Drosophila melanogaster development
Q21131404The viral and cellular microRNA targetome in lymphoblastoid cell lines
Q58283959Transcriptome-Wide Identification of Protein Binding Sites on RNA by PAR-CLIP (Photoactivatable-Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation)
Q24630900Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP
Q36431037Unique microRNAs appear at different times during the course of a delayed-type hypersensitivity reaction in human skin
Q37529560Urine microRNA as potential biomarkers of autosomal dominant polycystic kidney disease progression: description of miRNA profiles at baseline
Q33741262Viral DNA Replication Orientation and hnRNPs Regulate Transcription of the Human Papillomavirus 18 Late Promoter
Q24594085Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines
Q46310560miR-193b-Regulated Signaling Networks Serve as Tumor Suppressors in Liposarcoma and Promote Adipogenesis in Adipose-Derived Stem Cells
Q36109279miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development
Q39612232miRNA in situ hybridization in formaldehyde and EDC-fixed tissues
Q24628889miRNAs in human cancer
Q37659973microRNAs are biomarkers of oncogenic human papillomavirus infections
Q41010535siRNA Selection Server: an automated siRNA oligonucleotide prediction server
Q34310668siRNAs: applications in functional genomics and potential as therapeutics

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