MiR-26a enhances the radiosensitivity of glioblastoma multiforme cells through targeting of ataxia-telangiectasia mutated

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MiR-26a enhances the radiosensitivity of glioblastoma multiforme cells through targeting of ataxia-telangiectasia mutated is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YEXCR.2013.10.020
P698PubMed publication ID24211747

P2093author name stringYongming Qiu
Qing Mao
Jianwei Ge
Jin Lan
Pin Guo
Quanmin Nie
Liemei Guo
P2860cites workAberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell lineQ38288867
Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T-cell leukaemiaQ38343194
Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinomaQ39235192
MiR-181a confers resistance of cervical cancer to radiation therapy through targeting the pro-apoptotic PRKCD geneQ39305395
Transcriptional modulation of micro-RNA in human cells differing in radiation sensitivityQ39693567
DNA repair after irradiation in glioma cells and normal human astrocytesQ40092752
Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavirQ40136467
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiationQ40570996
Double strand break repair by homologous recombination is regulated by cell cycle-independent signaling via ATM in human glioma cellsQ40595350
ATM is a target for positive regulation by E2F-1.Q42806424
Counteracting tumor radioresistance by targeting DNA repairQ44647808
Expression of ATM protein and its relationship with p53 in pancreatic carcinoma with tissue arrayQ47733277
Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cellsQ21563320
MicroRNA-26a/b and their host genes cooperate to inhibit the G1/S transition by activating the pRb proteinQ24601263
MicroRNAs: target recognition and regulatory functionsQ24609584
The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivoQ24657924
Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damageQ24672492
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
ATM phosphorylates histone H2AX in response to DNA double-strand breaksQ28188651
Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-RasQ28267417
DNA damage responses: mechanisms and roles in human disease: 2007 G.H.A. Clowes Memorial Award LectureQ28276038
Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiationQ28287476
ATM: from gene to functionQ28611464
Malignant astrocytic glioma: genetics, biology, and paths to treatmentQ29618156
Atm-deficient mice: a paradigm of ataxia telangiectasiaQ29619532
Serine/threonine protein phosphatase 6 modulates the radiation sensitivity of glioblastomaQ30428996
Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorshipQ33719798
DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesisQ33814324
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AXQ34031720
miR-18a impairs DNA damage response through downregulation of ataxia telangiectasia mutated (ATM) kinase.Q34043212
H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy.Q34089263
Phosphatases in the cellular response to DNA damage.Q34198570
Down-regulation of microRNA-26a promotes mouse hepatocyte proliferation during liver regenerationQ34229869
Aggressive treatment is appropriate for glioblastoma multiforme patients 70 years old or older: a retrospective review of 206 casesQ34722872
Tying the loose ends together in DNA double strand break repair with 53BP1.Q35082739
Characteristics of gamma-H2AX foci at DNA double-strand breaks sitesQ35191534
Role of cell cycle in mediating sensitivity to radiotherapyQ35826593
Revival of the abandoned therapeutic wortmannin by nanoparticle drug delivery.Q35991577
Therapeutic advances in the treatment of glioblastoma: rationale and potential role of targeted agentsQ36395924
Treatment of glioblastoma multiforme: a new standardQ36420125
Absence of mutations in the ATM gene in breast cancer patients with severe responses to radiotherapyQ36431591
ATM activation and DNA damage responseQ36800838
DNA repair by homologous recombination, but not by nonhomologous end joining, is elevated in breast cancer cells.Q37229934
Phase II preradiation R115777 (tipifarnib) in newly diagnosed GBM with residual enhancing diseaseQ37284331
Molecular mechanisms of ultraviolet radiation-induced DNA damage and repairQ37826346
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectglioblastomaQ282142
P304page(s)200-208
P577publication date2013-11-05
P1433published inExperimental Cell ResearchQ1524289
P1476titleMiR-26a enhances the radiosensitivity of glioblastoma multiforme cells through targeting of ataxia-telangiectasia mutated
P478volume320

Reverse relations

cites work (P2860)
Q35198369ATM has a major role in the double-strand break repair pathway dysregulation in sporadic breast carcinomas and is an independent prognostic marker at both mRNA and protein levels.
Q57161414Aberrant miRNAs Regulate the Biological Hallmarks of Glioblastoma
Q49023583Analysis of EZH2: micro-RNA network in low and high grade astrocytic tumors
Q64067528Deregulated MicroRNA Signature Following Glioblastoma Irradiation
Q38606228Genomic integrity and the ageing brain
Q38393328Glioblastoma: molecular pathways, stem cells and therapeutic targets
Q38848860Inhibition of miR-630 enhances the cell resistance to radiation by directly targeting CDC14A in human glioma
Q38736898Loss of miR-26a-5p promotes proliferation, migration, and invasion in prostate cancer through negatively regulating SERBP1.
Q35140218MiR-124 Radiosensitizes human colorectal cancer cells by targeting PRRX1
Q38819398MiR-218-5p inhibits the stem cell properties and invasive ability of the A2B5⁺CD133⁻ subgroup of human glioma stem cells
Q38828580MiR-26a enhances the sensitivity of gastric cancer cells to cisplatin by targeting NRAS and E2F2
Q38958486MiR-451 increases radiosensitivity of nasopharyngeal carcinoma cells by targeting ras-related protein 14 (RAB14).
Q37476413MicroRNA-19b-3p regulates nasopharyngeal carcinoma radiosensitivity by targeting TNFAIP3/NF-κB axis
Q49790324MicroRNA-26a and Tumor
Q38827487MicroRNA-378g enhanced radiosensitivity of NPC cells partially by targeting protein tyrosine phosphatase SHP-1.
Q41116642MicroRNA-590-3p enhances the radioresistance in glioblastoma cells by targeting LRIG1.
Q28829013MicroRNAs Used in Combination with Anti-Cancer Treatments Can Enhance Therapy Efficacy
Q38497875MicroRNAs and cell cycle of malignant glioma
Q26747273MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics
Q41239908Targeting MicroRNAs in Prostate Cancer Radiotherapy
Q99591126The Role of Exosomes in Stemness and Neurodegenerative Diseases-Chemoresistant-Cancer Therapeutics and Phytochemicals
Q38796729The role of microRNA-26a in human cancer progression and clinical application
Q49762971miR‑328‑3p enhances the radiosensitivity of osteosarcoma and regulates apoptosis and cell viability via H2AX.
Q89720471microRNAs Orchestrate Pathophysiology of Breast Cancer Brain Metastasis: Advances in Therapy

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