Differential expression of PTEN-targeting microRNAs miR-19a and miR-21 in Cowden syndrome

scientific article published on May 2008

Differential expression of PTEN-targeting microRNAs miR-19a and miR-21 in Cowden syndrome is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.AJHG.2008.04.005
P932PMC publication ID2427229
P698PubMed publication ID18460397
P5875ResearchGate publication ID5393382

P50authorCharis EngQ37385393
P2093author name stringPetra Platzer
Marcus G Pezzolesi
Kristin A Waite
P2860cites workThe lipid phosphatase activity of PTEN is critical for its tumor supressor functionQ22007981
Germline PTEN promoter mutations and deletions in Cowden/Bannayan-Riley-Ruvalcaba syndrome result in aberrant PTEN protein and dysregulation of the phosphoinositol-3-kinase/Akt pathwayQ24532136
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemiaQ24539231
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemiasQ24564008
Protean PTEN: form and functionQ24613810
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Prediction of mammalian microRNA targetsQ27860498
MicroRNA gene expression deregulation in human breast cancerQ27860690
PTEN: one gene, many syndromesQ28203387
Reduced accumulation of specific microRNAs in colorectal neoplasiaQ28211976
High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphomaQ28236173
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cellsQ28262214
Cancer phenomics: RET and PTEN as illustrative modelsQ28278854
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTENQ28513537
Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell linesQ28975767
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancerQ29547523
Regulation of PTEN phosphorylation and stability by a tumor suppressor candidate protein.Q29977747
PTEN: a tumour suppressor that functions as a phospholipid phosphataseQ33594251
PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndromeQ34504165
Distinct expression profiles for PTEN transcript and its splice variants in Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome.Q34658356
Cowden syndrome-affected patients with PTEN promoter mutations demonstrate abnormal protein translationQ36430799
Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synucleinQ36718966
Comparative genomic and functional analyses reveal a novel cis-acting PTEN regulatory element as a highly conserved functional E-box motif deleted in Cowden syndromeQ38304010
Nuclear localization of PTEN is regulated by Ca(2+) through a tyrosil phosphorylation-independent conformational modification in major vault proteinQ40192972
BMP2 exposure results in decreased PTEN protein degradation and increased PTEN levelsQ44350476
Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutationQ45345194
Genetic background controls tumor development in PTEN-deficient mice.Q46241404
Germline mutations in PTEN are present in Bannayan-Zonana syndromeQ48046915
Early loss of heterozygosity on 17q in ovarian cancer. The Abe Ovarian Cancer Genetics Group.Q53487142
Localization of the gene for Cowden disease to chromosome 10q22–23Q57694734
PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell deathQ73229813
Loss of heterozygosity at chromosome 13q in hepatocellular carcinoma: identification of three independent regionsQ73446756
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectmicroRNAQ310899
P304page(s)1141-1149
P577publication date2008-05-01
P1433published inAmerican Journal of Human GeneticsQ4744249
P1476titleDifferential expression of PTEN-targeting microRNAs miR-19a and miR-21 in Cowden syndrome
P478volume82

Reverse relations

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