TET3 inhibits TGF-β1-induced epithelial-mesenchymal transition by demethylating miR-30d precursor gene in ovarian cancer cells

scientific article published on 4 May 2016

TET3 inhibits TGF-β1-induced epithelial-mesenchymal transition by demethylating miR-30d precursor gene in ovarian cancer cells is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1007710492
P356DOI10.1186/S13046-016-0350-Y
P932PMC publication ID4855705
P698PubMed publication ID27141829

P2093author name stringWei Chen
Jie Li
Xu Li
Lijie Wang
Xia Zheng
Le Zhao
He Chen
Jiaojiao Lu
Xi Han
Huilian Hou
Zhongxue Ye
P2860cites workImpaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2Q24306181
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1Q24316558
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosineQ24614582
Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignanciesQ24648438
The basics of epithelial-mesenchymal transitionQ24652992
The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivoQ24657924
Central role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic interventionQ26864839
Targeting TGF-β signaling in cancerQ27012443
Cancer statistics, 2015Q27860576
TGF-β regulates DNA methyltransferase expression in prostate cancer, correlates with aggressive capabilities, and predicts disease recurrenceQ28477306
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specificationQ28504641
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosineQ28585429
Cancer epigenetics: from mechanism to therapyQ29614799
X inactivation, differentiation, and DNA methylationQ33999850
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylationQ34258768
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanomaQ34299814
TET1 suppresses cancer invasion by activating the tissue inhibitors of metalloproteinasesQ34301250
NANOG-dependent function of TET1 and TET2 in establishment of pluripotencyQ34327015
Tumor suppression by miR-26 overrides potential oncogenic activity in intestinal tumorigenesisQ34590225
Promoter methylation of tumor suppressor genes in pre-neoplastic lesions; potential marker of disease recurrence.Q34762217
TGF-β1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinomaQ35273414
Clinical significance of DNA methylation mRNA levels of TET family members in colorectal cancer.Q35749302
Global profiling of DNA methylation erasure in mouse primordial germ cellsQ35864711
TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cellsQ36213724
Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cellsQ36934066
miR-29 represses the activities of DNA methyltransferases and DNA demethylasesQ37091993
Ten-eleven translocation (Tet) and thymine DNA glycosylase (TDG), components of the demethylation pathway, are direct targets of miRNA-29aQ37157046
MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiationQ37276461
An extensive network of TET2-targeting MicroRNAs regulates malignant hematopoiesisQ37327706
miR-30d Blocked Transforming Growth Factor β1-Induced Epithelial-Mesenchymal Transition by Targeting Snail in Ovarian Cancer CellsQ38824925
TET2 repression by androgen hormone regulates global hydroxymethylation status and prostate cancer progressionQ38832692
TET3 mediates the activation of human hepatic stellate cells via modulating the expression of long non-coding RNA HIF1A-AS1.Q38924188
Nuclear exclusion of TET1 is associated with loss of 5-hydroxymethylcytosine in IDH1 wild-type gliomasQ39333118
miR-29b as a therapeutic agent for angiotensin II-induced cardiac fibrosis by targeting TGF-β/Smad3 signalingQ39413020
Involvement of miRNA-29a in epigenetic regulation of transforming growth factor-β-induced epithelial-mesenchymal transition in hepatocellular carcinoma.Q53101387
TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23).Q55036452
DNA modification mechanisms and gene activity during developmentQ66907977
P921main subjectovarian cancerQ172341
P304page(s)72
P577publication date2016-05-04
P1433published inJournal of Experimental & Clinical Cancer ResearchQ13739415
P1476titleTET3 inhibits TGF-β1-induced epithelial-mesenchymal transition by demethylating miR-30d precursor gene in ovarian cancer cells
P478volume35

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cites work (P2860)
Q91717197Aberrant hypermethylation-mediated downregulation of antisense lncRNA ZNF667-AS1 and its sense gene ZNF667 correlate with progression and prognosis of esophageal squamous cell carcinoma
Q47303229CR6-interacting factor 1 inhibits invasiveness by suppressing TGF-β-mediated epithelial-mesenchymal transition in hepatocellular carcinoma
Q89514240Epigenetic induction of tumor stemness via the lipopolysaccharide-TET3-HOXB2 signaling axis in esophageal squamous cell carcinoma
Q90630066Expression and prognosis analysis of TET family in acute myeloid leukemia
Q90705372Glyphosate Primes Mammary Cells for Tumorigenesis by Reprogramming the Epigenome in a TET3-Dependent Manner
Q37221246Induction of the mesenchymal to epithelial transition by demethylation-activated microRNA-125b is involved in the anti-migration/invasion effects of arsenic trioxide on human chondrosarcoma
Q64227434Methylation and ovarian cancer: Can DNA methylation be of diagnostic use?
Q58788954MicroRNA-200 and microRNA-30 family as prognostic molecular signatures in ovarian cancer: A meta-analysis
Q92221539Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials

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