| biological pathway | Q4915012 |
| P2888 | exact match | https://identifiers.org/reactome:R-HSA-2219528 |
| P3937 | Reactome ID | R-HSA-2219528 |
| P2860 | cites work | The oncogenic properties of mutant p110alpha and p110beta phosphatidylinositol 3-kinases in human mammary epithelial cells | Q34234737 |
| PIK3R1 (p85α) is somatically mutated at high frequency in primary endometrial cancer | Q35050913 | ||
| PTEN loss in the continuum of common cancers, rare syndromes and mouse models. | Q37856722 | ||
| Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation | Q39766760 | ||
| Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells. | Q40006122 | ||
| Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation | Q45345194 | ||
| AKT/PKB signaling: navigating downstream | Q24657857 | ||
| The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo | Q24657924 | ||
| Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association | Q27620298 | ||
| A transforming mutation in the pleckstrin homology domain of AKT1 in cancer | Q27646556 | ||
| Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit | Q27646654 | ||
| The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations | Q27649316 | ||
| PTEN1 is frequently mutated in primary endometrial carcinomas | Q28250937 | ||
| Functional evaluation of PTEN missense mutations using in vitro phosphoinositide phosphatase assay | Q28611936 | ||
| Targeting the phosphoinositide 3-kinase pathway in cancer | Q29615809 | ||
| Hot-spot mutations in p110alpha of phosphatidylinositol 3-kinase (pI3K): differential interactions with the regulatory subunit p85 and with RAS. | Q33716552 | ||
| Molecular mechanism of an oncogenic mutation that alters membrane targeting: Glu17Lys modifies the PIP lipid specificity of the AKT1 PH domain | Q34057438 | ||
| Cancer-derived mutations in the regulatory subunit p85alpha of phosphoinositide 3-kinase function through the catalytic subunit p110alpha | Q34100548 | ||
| P703 | found in taxon | Homo sapiens | Q15978631 |
| P527 | has part(s) | Constitutive Signaling by Aberrant PI3K in Cancer | Q45314384 |
| Constitutive Signaling by AKT1 E17K in Cancer | Q45314386 | ||
| PTEN Loss of Function in Cancer | Q45314387 | ||
| P361 | part of | Diseases of signal transduction by growth factor receptors and second messengers | Q45314348 |
| Q45314348 | Diseases of signal transduction by growth factor receptors and second messengers | has part(s) | P527 |
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