review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Xinjiang Wang | |
Xuejun Jiang | |||
Yuji Shi | |||
Benjamin E Paluch | |||
P2860 | cites work | miR-22 forms a regulatory loop in PTEN/AKT pathway and modulates signaling kinetics | Q21091130 |
Phosphorylation of the PTEN tail regulates protein stability and function | Q22254305 | ||
The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation | Q24290417 | ||
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN | Q24292919 | ||
Ubiquitination regulates PTEN nuclear import and tumor suppression | Q24292946 | ||
PCAF modulates PTEN activity | Q24296629 | ||
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta | Q24310394 | ||
Rak functions as a tumor suppressor by regulating PTEN protein stability and function | Q24312999 | ||
X-linked inhibitor of apoptosis protein (XIAP) regulates PTEN ubiquitination, content, and compartmentalization | Q24314543 | ||
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN | Q24322051 | ||
Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner | Q24337323 | ||
Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a | Q24613036 | ||
Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2 | Q24623513 | ||
In vivo identification of tumor- suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma | Q24629400 | ||
E3 ligase Nedd4 promotes axon branching by downregulating PTEN | Q24630190 | ||
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology | Q24632651 | ||
The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo | Q24657924 | ||
Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation | Q24673801 | ||
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
Crucial role of the C-terminus of PTEN in antagonizing NEDD4-1-mediated PTEN ubiquitination and degradation | Q28281043 | ||
A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN. | Q28305284 | ||
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration | Q28384823 | ||
Essential role for nuclear PTEN in maintaining chromosomal integrity | Q28513781 | ||
Inactivation of platelet-derived growth factor receptor by the tumor suppressor PTEN provides a novel mechanism of action of the phosphatase | Q28567492 | ||
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer | Q29547523 | ||
Reversible inactivation of the tumor suppressor PTEN by H2O2 | Q29615204 | ||
Direct positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase | Q30156937 | ||
Shank-interacting protein-like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells. | Q30494717 | ||
Oxidation of DJ-1-dependent cell transformation through direct binding of DJ-1 to PTEN. | Q33514644 | ||
Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc | Q33744696 | ||
Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway | Q34173253 | ||
Regulation of PTEN by Rho small GTPases | Q34406790 | ||
Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane | Q34574432 | ||
The putative tumor suppressor gene GLTSCR2 induces PTEN-modulated cell death | Q34656554 | ||
PTEN acetylation modulates its interaction with PDZ domain | Q34817146 | ||
On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN) | Q35064223 | ||
Mechanistic analysis of a DNA damage-induced, PTEN-dependent size checkpoint in human cells | Q35096583 | ||
Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression | Q35223274 | ||
Induction of apoptotic genes by a p73-phosphatase and tensin homolog (p73-PTEN) protein complex in response to genotoxic stress | Q35379204 | ||
Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia | Q35666277 | ||
Redox regulation of PI 3-kinase signalling via inactivation of PTEN | Q36266420 | ||
Shc and FAK differentially regulate cell motility and directionality modulated by PTEN. | Q36301565 | ||
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia | Q37009642 | ||
New insights into PTEN. | Q37011116 | ||
Portrait of PTEN: messages from mutant mice. | Q37059129 | ||
Tenets of PTEN tumor suppression | Q37154214 | ||
PTEN and the PI3-kinase pathway in cancer | Q37259680 | ||
The roles of PTEN in development, physiology and tumorigenesis in mouse models: a tissue-by-tissue survey | Q37270420 | ||
The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells | Q37452295 | ||
WWP2 is an E3 ubiquitin ligase for PTEN. | Q37588182 | ||
Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors | Q37693081 | ||
PTEN level in tumor suppression: how much is too little? | Q37832338 | ||
E-cadherin inhibits tumor cell growth by suppressing PI3K/Akt signaling via β-catenin-Egr1-mediated PTEN expression. | Q39597035 | ||
Ubiquitination of PTEN (phosphatase and tensin homolog) inhibits phosphatase activity and is enhanced by membrane targeting and hyperosmotic stress. | Q39736424 | ||
The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network | Q39948774 | ||
PTEN is destabilized by phosphorylation on Thr366. | Q40143795 | ||
CBF-1 (RBP-J kappa) binds to the PTEN promoter and regulates PTEN gene expression | Q40179833 | ||
Localization of agonist-sensitive PtdIns(3,4,5)P3 reveals a nuclear pool that is insensitive to PTEN expression. | Q40198370 | ||
Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta | Q40384036 | ||
Increased protein expression of the PTEN tumor suppressor in the presence of constitutively active Notch-1. | Q40386132 | ||
Regulation of cell migration by the C2 domain of the tumor suppressor PTEN. | Q40587498 | ||
Regulation of PTEN activity by its carboxyl-terminal autoinhibitory domain | Q42827470 | ||
Distinct functional outputs of PTEN signalling are controlled by dynamic association with β-arrestins. | Q42865771 | ||
PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils | Q44857079 | ||
Mechanistic insights into maintenance of high p53 acetylation by PTEN. | Q46035699 | ||
Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool. | Q46779760 | ||
Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas. | Q52180037 | ||
P433 | issue | Pt 20 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 4687-4692 | |
P577 | publication date | 2012-10-01 | |
P1433 | published in | Journal of Cell Science | Q1524177 |
P1476 | title | PTEN at a glance | |
P478 | volume | 125 |