NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration

scientific article published on November 10, 2010

NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1029865290
P356DOI10.1186/1750-1326-5-49
P953full work available at URLhttp://www.molecularneurodegeneration.com/content/5//49
https://molecularneurodegeneration.biomedcentral.com/counter/pdf/10.1186/1750-1326-5-49
http://www.molecularneurodegeneration.com/content/5//49/abstract
http://www.molecularneurodegeneration.com/content/pdf/1750-1326-5-49.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21067594/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21067594/?tool=EBI
https://europepmc.org/articles/PMC2992530
https://europepmc.org/articles/PMC2992530?pdf=render
https://link.springer.com/content/pdf/10.1186/1750-1326-5-49.pdf
P3181OpenCitations bibliographic resource ID2880813
P932PMC publication ID2992530
P698PubMed publication ID21067594
P5875ResearchGate publication ID47741850

P50authorStuart A. LiptonQ1520410
Eliezer MasliahQ28324209
P2093author name stringXue Zhang
Tao Ma
Huaxi Xu
Shiyong Diao
Janet Hsu
Francesca-Fang Liao
Young-Don Kwak
Yaomin Chen
P2860cites workPost-translational regulation of PTEN.Q37270440
Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling.Q37377515
CK2 is a novel negative regulator of NADPH oxidase and a neuroprotectant in mice after cerebral ischemiaQ37449836
Nitric oxide in cell survival: a janus moleculeQ37532468
Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factorsQ37693081
Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complexQ39229072
Hydrogen peroxide inhibits mTOR signaling by activation of AMPKalpha leading to apoptosis of neuronal cellsQ39741931
PTEN is destabilized by phosphorylation on Thr366.Q40143795
S-nitrosylation of IRP2 regulates its stability via the ubiquitin-proteasome pathwayQ40376784
Redox regulation of PTEN by S-nitrosothiolsQ40406877
Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR.Q42091923
Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69.Q42526186
The biotin switch method for the detection of S-nitrosylated proteinsQ43830334
Role of protein kinase B in Alzheimer's neurofibrillary pathologyQ44354353
Tumor-suppressor PTEN affects tau phosphorylation, aggregation, and binding to microtubulesQ46176212
Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathologyQ46386533
PTEN levels in Alzheimer's disease medial temporal cortexQ46765558
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylationQ46785508
PTEN activity is modulated during ischemia and reperfusion: involvement in the induction and decay of preconditioningQ46801102
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos diseaseQ47198022
Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivoQ48722189
Akt activation by arachidonic acid metabolism occurs via oxidation and inactivation of PTEN tumor suppressor.Q53564939
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease – is this type 3 diabetes?Q56049682
Phosphorylation of the PTEN tail regulates protein stability and functionQ22254305
Role of S-nitrosylation in apoptosis resistance and carcinogenesisQ23909851
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTENQ24292919
Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalitiesQ24303650
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphateQ24317714
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseQ24322705
E3 ligase Nedd4 promotes axon branching by downregulating PTENQ24630190
Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathwayQ24644113
Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane associationQ27620298
Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuseQ28297001
Nitric oxide regulates lung carcinoma cell anoikis through inhibition of ubiquitin-proteasomal degradation of caveolin-1Q28392426
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systemsQ28586004
Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelinationQ28591752
Ischemic Postconditioning as a Novel Avenue to Protect against Brain Injury after StrokeQ29394624
A role for nuclear PTEN in neuronal differentiation.Q29568319
Reversible inactivation of the tumor suppressor PTEN by H2O2Q29615204
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?Q29619535
Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activityQ30448692
Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairmentQ33740552
Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zincQ33744696
PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injuryQ33892209
Protein S-nitrosylation in health and disease: a current perspectiveQ35020178
Redox regulation of PI 3-kinase signalling via inactivation of PTENQ36266420
Nitric oxide-dependent proteasomal degradation of cytochrome P450 2B proteinsQ36343293
Cerebral preconditioning and ischaemic toleranceQ36484538
GSK-3 is essential in the pathogenesis of Alzheimer's disease.Q36568147
PTEN, the Achilles' heel of myocardial ischaemia/reperfusion injury?Q36733630
Phosphatase PTEN in neuronal injury and brain disordersQ36980931
Phosphorylation keeps PTEN phosphatase closed for businessQ37083611
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectneurodegenerationQ1755122
P304page(s)49
P577publication date2010-11-10
P1433published inMolecular NeurodegenerationQ15817329
P1476titleNO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration
P478volume5

Reverse relations

cites work (P2860)
Q38110376Aberrant protein s-nitrosylation in neurodegenerative diseases
Q45345903Analysis of PTEN ubiquitylation and SUMOylation using molecular traps.
Q36093051Ca2+ Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid Metabolism
Q58781601Computational Structural Biology of -nitrosylation of Cancer Targets
Q38758536Controlling PTEN (Phosphatase and Tensin Homolog) Stability: A DOMINANT ROLE FOR LYSINE 66.
Q36674615Cytoprotective signaling associated with nitric oxide upregulation in tumor cells subjected to photodynamic therapy-like oxidative stress
Q34686983Differential regulation of BACE1 expression by oxidative and nitrosative signals
Q33942934Distinction of thioredoxin transnitrosylation and denitrosylation target proteins by the ICAT quantitative approach.
Q46210613External cys/cySS redox state modification controls the intracellular redox state and neurodegeneration via Akt in aging and Alzheimer's disease mouse model neurons
Q26851901Gasotransmitters in Gametogenesis and Early Development: Holy Trinity for Assisted Reproductive Technology-A Review
Q24610496Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in nondiabetics)
Q49532909Identification of Novel Signal Transduction, Immune Function, and Oxidative Stress Genes and Pathways by Topiramate for Treatment of Methamphetamine Dependence Based on Secondary Outcomes
Q37384680Increased carbonylation of the lipid phosphatase PTEN contributes to Akt2 activation in a murine model of early alcohol-induced steatosis
Q38027944Insulin and IGF-1 signalling: longevity, protein homoeostasis and Alzheimer's disease.
Q38102887Methods for detection and characterization of protein S-nitrosylation
Q36767908Mitochondrial dysfunction and cell death in neurodegenerative diseases through nitroxidative stress
Q35787066Mitochondrial ubiquitin ligase MITOL blocks S-nitrosylated MAP1B-light chain 1-mediated mitochondrial dysfunction and neuronal cell death
Q92265566Modifying PTEN recruitment promotes neuron survival, regeneration, and functional recovery after CNS injury
Q89552362Modulation of AMPA Receptors by Nitric Oxide in Nerve Cells
Q28079319Modulation of the Anti-Tumor Efficacy of Photodynamic Therapy by Nitric Oxide
Q62675748Myalgic encephalomyelitis or chronic fatigue syndrome: how could the illness develop?
Q37652356NOS1 S-nitrosylates PTEN and inhibits autophagy in nasopharyngeal carcinoma cells
Q33775384Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain.
Q50222232Nitric Oxide Upregulates Proteasomal Protein Degradation in Neurons.
Q34451436Nitric oxide and histone deacetylases modulate cocaine-induced mu-opioid receptor levels in PC12 cells
Q38706678Nitric oxide-regulated proteolysis of human CYP2B6 via the ubiquitin-proteasome system
Q23921938Nitrosothiol signaling in anoikis resistance and cancer metastasis
Q38191314Novel approaches and opportunities for cardioprotective signaling through 3',5'-cyclic guanosine monophosphate manipulation.
Q35064223On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN)
Q46402658PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation
Q64070918PTEN S-nitrosylation by NOS1 inhibits autophagy in NPC cells
Q36452913PTEN at a glance
Q28512531PTEN degradation after ischemic stroke: a double-edged sword
Q48066104PTEN recruitment controls synaptic and cognitive function in Alzheimer's models.
Q54977045Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer.
Q38199441Protein S-nitrosylation in preconditioning and postconditioning
Q35653222Protein S-nitrosylation: role for nitric oxide signaling in neuronal death
Q26852767Protein-thiol oxidation and cell death: regulatory role of glutaredoxins
Q37111504Redox pioneer: Professor Stuart A. Lipton
Q35763044Regulation by S-nitrosylation of protein post-translational modification
Q47691876Regulation of the tumor suppressor PTEN by natural anticancer compounds
Q89172382Role of Nitric Oxide and Hydrogen Sulfide in Ischemic Stroke and the Emergent Epigenetic Underpinnings
Q41463056Role of PTEN-Akt-CREB Signaling Pathway in Nervous System impairment of Rats with Chronic Arsenite Exposure
Q35492444S-nitrosylation in the regulation of gene transcription
Q39070800S-nitrosylation of ascorbate peroxidase is part of programmed cell death signaling in tobacco Bright Yellow-2 cells
Q36266253S-nitrosylation triggers ABI5 degradation to promote seed germination and seedling growth
Q36266295S-nitrosylation-dependent proteasomal degradation restrains Cdk5 activity to regulate hippocampal synaptic strength
Q35693498S-nitrosylation: a radical way to protect the heart
Q37204147S-nitrosylation: specificity, occupancy, and interaction with other post-translational modifications
Q36232644SNOs Differ: Methodological and Biological Implications
Q39328325SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane
Q38179749Signaling by S-nitrosylation in the heart
Q26823024Strategies for profiling native S-nitrosylation
Q27022790Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders
Q38397575Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases
Q37209584TNF-α induces vascular insulin resistance via positive modulation of PTEN and decreased Akt/eNOS/NO signaling in high fat diet-fed mice.
Q60584712The Emerging Role of Protein S-Nitrosylation in Cancer Metastasis
Q38400601The Essential Role of Soluble Aβ Oligomers in Alzheimer's Disease
Q88955683The functions and regulation of the PTEN tumour suppressor: new modes and prospects
Q38222880The role of post-translational modifications in acute and chronic cardiovascular disease
Q90669787The roles of S-nitrosylation and S-glutathionylation in Alzheimer's disease
Q38809310To eat, or NOt to eat: S-nitrosylation signaling in autophagy.
Q34451736Transnitrosylation from DJ-1 to PTEN attenuates neuronal cell death in parkinson's disease models
Q24613053Upregulation of the E3 ligase NEDD4-1 by oxidative stress degrades IGF-1 receptor protein in neurodegeneration

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