scholarly article | Q13442814 |
P2093 | author name string | W Poluha | |
A H Ross | |||
S Ohta | |||
B G Neel | |||
S J Miller | |||
S Lambert | |||
P J Quesenberry | |||
N Sultana | |||
L D Recht | |||
N S Litofsky | |||
C M Schonhoff | |||
P Mitra | |||
M B Lachyankar | |||
R Nabi | |||
P2860 | cites work | The lipid phosphatase activity of PTEN is critical for its tumor supressor function | Q22007981 |
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta | Q24310394 | ||
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN | Q24322051 | ||
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors | Q24652341 | ||
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery | Q27860586 | ||
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta | Q28255046 | ||
Different mechanisms for inhibition of cell proliferation via cell cycle proteins in PC12 cells by nerve growth factor and staurosporine | Q73670115 | ||
A novel, nerve growth factor-activated pathway involving nitric oxide, p53, and p21WAF1 regulates neuronal differentiation of PC12 cells | Q73692291 | ||
Phosphoinositide 3-kinase in rat liver nuclei | Q74457529 | ||
Regulation of CBP-mediated transcription by neuronal calcium signaling | Q77407722 | ||
Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system | Q28292445 | ||
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
Pten is essential for embryonic development and tumour suppression | Q28509238 | ||
Essential role for nuclear phospholipase C beta1 in insulin-like growth factor I-induced mitogenesis | Q28512471 | ||
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN | Q28513537 | ||
Role of translocation in the activation and function of protein kinase B | Q28609902 | ||
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome | Q29615538 | ||
Growth factors, glia and gliomas | Q32137526 | ||
PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells | Q33586807 | ||
Cowden syndrome and Lhermitte-Duclos disease in a family: a single genetic syndrome with pleiotropy? | Q33674349 | ||
A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice | Q35211546 | ||
Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways | Q36256326 | ||
The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells | Q36557701 | ||
Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes | Q36564714 | ||
Cytoplasmic and nuclear localization sites of phosphatidylinositol 3-kinase in human osteosarcoma sensitive and multidrug-resistant Saos-2 cells | Q36836176 | ||
Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation | Q39576120 | ||
The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells | Q40993616 | ||
Phosphorothioate antisense oligodeoxynucleotides: questions of specificity | Q40995498 | ||
Signalling pathways: jack of all cascades | Q41110511 | ||
Beta-catenin: a key mediator of Wnt signaling | Q41732761 | ||
Synergy between interferon-gamma and tumor necrosis factor-alpha in transcriptional activation is mediated by cooperation between signal transducer and activator of transcription 1 and nuclear factor kappaB. | Q42439020 | ||
A role for nuclear phosphatidylinositol-specific phospholipase C in the G2/M phase transition | Q42445558 | ||
Akt-dependent potentiation of L channels by insulin-like growth factor-1 is required for neuronal survival | Q42468713 | ||
Insulin receptor substrate-1 (IRS-1) distribution in the rat central nervous system. | Q42493263 | ||
Evidence that a phosphatidylinositol 3,4,5-trisphosphate-binding protein can function in nucleus | Q42819910 | ||
Nuclear diacylglycerol produced by phosphoinositide-specific phospholipase C is responsible for nuclear translocation of protein kinase C-alpha. | Q42825155 | ||
Immunocytochemical detection of phosphatidylinositol 4,5-bisphosphate localization sites within the nucleus. | Q42830321 | ||
Multiple isoforms of the regulatory subunit for phosphatidylinositol 3-kinase (PI3-kinase) are expressed in neurons in the rat brain | Q48018986 | ||
Control of recruitment and transcription-activating function of CBP determines gene regulation by NMDA receptors and L-type calcium channels | Q48219511 | ||
Role of phosphatidylinositol 3-kinase in angiotensin II regulation of norepinephrine neuromodulation in brain neurons of the spontaneously hypertensive rat. | Q48257447 | ||
A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes | Q48413417 | ||
IGF-1 modulates N and L calcium channels in a PI 3-kinase-dependent manner | Q48644004 | ||
Embryonic precursor cells that express Trk receptors: induction of different cell fates by NGF, BDNF, NT-3, and CNTF. | Q48736148 | ||
Differential expression of neurofilament triplet proteins in brain development | Q48921941 | ||
Nuclear phosphoinositide-specific phospholipase C, phosphatidylinositol 4,5-bisphosphate and protein kinase C during rat spermatogenesis. | Q52199631 | ||
Localization of mRNA for phosphatidylinositol 3-kinase in brain of developing and mature rats. | Q52204325 | ||
Premature p34cdc2 activation required for apoptosis. | Q52514157 | ||
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice | Q58378937 | ||
Nuclear translocation of phosphatidylinositol 3-kinase in rat pheochromocytoma PC 12 cells after treatment with nerve growth factor | Q62017175 | ||
Expression of a constitutively active phosphatidylinositol 3-kinase induces process formation in rat PC12 cells. Use of Cre/loxP recombination system | Q64382387 | ||
Bannayan-Riley-Ruvalcaba syndrome | Q67509446 | ||
The lack of a role for protein kinase C in neurite extension and in the induction of ornithine decarboxylase by nerve growth factor in PC12 cells | Q69942863 | ||
BDNF enhances the differentiation but not the survival of CNS stem cell- derived neuronal precursors | Q71978743 | ||
Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase | Q72068658 | ||
Impaired Fas response and autoimmunity in Pten+/- mice | Q73019160 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1404-1413 | |
P577 | publication date | 2000-02-01 | |
P1433 | published in | Journal of Neuroscience | Q1709864 |
P1476 | title | A role for nuclear PTEN in neuronal differentiation | |
P478 | volume | 20 |
Q38926213 | A PTEN-Regulated Checkpoint Controls Surface Delivery of δ Opioid Receptors |
Q35534634 | A conserved PTEN/FOXO pathway regulates neuronal morphology during C. elegans development |
Q39666296 | A mutant form of PTEN linked to autism |
Q33936020 | AAVshRNA-mediated suppression of PTEN in adult rats in combination with salmon fibrin administration enables regenerative growth of corticospinal axons and enhances recovery of voluntary motor function after cervical spinal cord injury |
Q34722525 | AMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressor |
Q29568315 | Activation of PPAR-γ and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells |
Q37063488 | Active zone density is conserved during synaptic growth but impaired in aged mice |
Q36735198 | Akt phosphorylation and nuclear phosphoinositide association mediate mRNA export and cell proliferation activities by ALY. |
Q28575231 | An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor-stimulated PC12 cells |
Q38074874 | Bergmann glia function in granule cell migration during cerebellum development |
Q38214592 | Brain patterning perturbations following PTEN loss |
Q36313163 | Class reunion: PTEN joins the nuclear crew. |
Q34581012 | Conditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development |
Q47198022 | Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease |
Q34859989 | Deregulated proliferation and differentiation in brain tumors. |
Q34104238 | Developmental mechanisms in the pathogenesis of neurodegenerative diseases |
Q33895317 | Different conformations of phosphatase and tensin homolog, deleted on chromosome 10 (PTEN) protein within the nucleus and cytoplasm of neurons |
Q36529884 | Differential roles of GluN2A- and GluN2B-containing NMDA receptors in neuronal survival and death. |
Q28297001 | Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse |
Q37442718 | Estrogen partially down-regulates PTEN to prevent apoptosis in VSC4.1 motoneurons following exposure to IFN-gamma |
Q43375954 | Expression of MicroRNA-29a Regulated by Yes-Associated Protein Modulates the Neurite Outgrowth in N2a Cells. |
Q35842249 | Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas |
Q37452592 | Functional Genomics Identifies Tis21-Dependent Mechanisms and Putative Cancer Drug Targets Underlying Medulloblastoma Shh-Type Development. |
Q33744696 | Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc |
Q35700587 | Glutamate signaling to Ras-MAPK in striatal neurons: mechanisms for inducible gene expression and plasticity |
Q73410694 | Heterogeneous lack of expression of the tumour suppressor PTEN protein in human neoplastic tissues |
Q27332424 | Hyperactive mTOR signals in the proopiomelanocortin-expressing hippocampal neurons cause age-dependent epilepsy and premature death in mice |
Q44219113 | Increased expression of phosphatase and tensin homolog in reactive astrogliosis following intracerebroventricular kainic acid injection in mouse hippocampus |
Q28576729 | Inhibition of neuronal phenotype by PTEN in PC12 cells |
Q55394781 | Intermittent fasting uncovers and rescues cognitive phenotypes in PTEN neuronal haploinsufficient mice. |
Q38266259 | Is Cytoplasmic PTEN a Specific Target for Neuronal Survival? |
Q45004411 | Lactacystin-induced apoptosis of cultured mouse cortical neurons is associated with accumulation of PTEN in the detergent-resistant membrane fraction. |
Q44645813 | Levels of PTEN protein modulate Akt phosphorylation on serine 473, but not on threonine 308, in IGF-II-overexpressing rhabdomyosarcomas cells |
Q35148037 | MiR-486 regulates lactation and targets the PTEN gene in cow mammary glands |
Q41685860 | MicroRNA-29c/PTEN pathway is involved in mice brain development and modulates neurite outgrowth in PC12 cells |
Q33843600 | Modulation in activation and expression of phosphatase and tensin homolog on chromosome ten, Akt1, and 3-phosphoinositide-dependent kinase 1: further evidence demonstrating altered phosphoinositide 3-kinase signaling in postmortem brain of suicide s |
Q37167943 | Modulation of inositol polyphosphate levels regulates neuronal differentiation |
Q90674893 | Molecular Factors Involved in Spinal Muscular Atrophy Pathways as Possible Disease-modifying Candidates |
Q35745875 | Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells |
Q28384823 | NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration |
Q42076186 | Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation |
Q79448445 | Nuclear PTEN: a tale of many tails |
Q35574004 | Nuclear Phosphoinositides and Their Functions |
Q35120151 | Nuclear lipid signalling |
Q35574286 | Nuclear lipids: key signaling effectors in the nervous system and other tissues |
Q28564702 | Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs |
Q39159757 | Nuclear phosphoinositide regulation of chromatin. |
Q34047274 | Nuclear tyrosine phosphorylation: the beginning of a map. |
Q42117421 | Opening the conformation is a master switch for the dual localization and phosphatase activity of PTEN. |
Q24296629 | PCAF modulates PTEN activity |
Q26862544 | PI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasms |
Q38759310 | PTEN Promotes Dopaminergic Neuronal Differentiation Through Regulation of ERK-Dependent Inhibition of S6K Signaling in Human Neural Stem Cells |
Q92316075 | PTEN Tumor-Suppressor: The Dam of Stemness in Cancer |
Q34942330 | PTEN function in mammalian cell size regulation |
Q24528114 | PTEN function: how normal cells control it and tumour cells lose it |
Q51597378 | PTEN gene: a model for genetic diseases in dermatology. |
Q28505099 | PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression |
Q26995683 | PTEN plasticity: how the taming of a lethal gene can go too far |
Q37620711 | PTEN regulates AMPA receptor-mediated cell viability in iPS-derived motor neurons. |
Q44352367 | PTEN regulates Akt kinase activity in hippocampal neurons and increases their sensitivity to glutamate and apoptosis |
Q54411913 | PTEN suppression promotes neurite development exclusively in differentiating PC12 cells via PI3‐kinase and MAP kinase signaling |
Q50977901 | PTEN, Longevity and Age-Related Diseases. |
Q48889007 | PTEN-mediated Akt activation in human neocortex during prenatal development |
Q35087328 | PTEN: Multiple Functions in Human Malignant Tumors |
Q34540849 | PTEN: The down side of PI 3-kinase signalling. |
Q37216319 | PTEN: a default gate-keeping tumor suppressor with a versatile tail |
Q37270432 | PTEN: a new guardian of the genome. |
Q89700534 | Phosphatase and tensin homologue: a therapeutic target for SMA |
Q37065263 | Phosphoinositide 5- and 3-phosphatase activities of a voltage-sensing phosphatase in living cells show identical voltage dependence |
Q90049726 | Phosphoinositides: Regulators of Nervous System Function in Health and Disease |
Q46978123 | Plot against pot. |
Q37270440 | Post-translational regulation of PTEN. |
Q34374013 | ProNGF induces PTEN via p75NTR to suppress Trk-mediated survival signaling in brain neurons |
Q24613810 | Protean PTEN: form and function |
Q37257205 | Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex |
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Q64102074 | Recent advances in understanding phosphoinositide signaling in the nervous system |
Q48259772 | Restoring Lost Excitability: Regenerating CNS Axons Inch Toward Electrogenicity. |
Q42452984 | Role of PTEN and Akt in the regulation of growth and apoptosis in human osteoblastic cells |
Q33502757 | Selective deletion of PTEN in dopamine neurons leads to trophic effects and adaptation of striatal medium spiny projecting neurons |
Q38259905 | Study of PTEN subcellular localization |
Q27022790 | Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders |
Q28343581 | Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions |
Q28678030 | The adaptive significance of adult neurogenesis: an integrative approach |
Q26778641 | The associations between Parkinson's disease and cancer: the plot thickens |
Q38148036 | The function, mechanisms, and role of the genes PTEN and TP53 and the effects of asbestos in the development of malignant mesothelioma: a review focused on the genes' molecular mechanisms |
Q34973870 | The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system. |
Q27005807 | The potential origin of glioblastoma initiating cells |
Q28564474 | The transcriptional response to hypoxic insult controlled by FRA-2 |
Q41440571 | Therapeutic strategies for spinal muscular atrophy: SMN and beyond. |
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