| scholarly article | Q13442814 |
| P50 | author | Carmelo Schepis | Q64005926 |
| Corrado Romano | Q42141950 | ||
| P2093 | author name string | Carmelo Schepis | |
| P2860 | cites work | The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation | Q24290417 |
| Ubiquitination regulates PTEN nuclear import and tumor suppression | Q24292946 | ||
| PCAF modulates PTEN activity | Q24296629 | ||
| TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta | Q24310394 | ||
| Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN | Q24322051 | ||
| P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
| PTEN function: how normal cells control it and tumour cells lose it | Q24528114 | ||
| A microRNA expression signature of human solid tumors defines cancer gene targets | Q24541455 | ||
| Protean PTEN: form and function | Q24613810 | ||
| Mutation and cancer: statistical study of retinoblastoma | Q24618185 | ||
| Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis | Q24681977 | ||
| PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
| Loss of PTEN facilitates HIF-1-mediated gene expression | Q28145476 | ||
| PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model | Q28202775 | ||
| PTEN: one gene, many syndromes | Q28203387 | ||
| MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells | Q28262214 | ||
| The ubiquitin-proteasome system | Q28305844 | ||
| Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
| Pten is essential for embryonic development and tumour suppression | Q28509238 | ||
| Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems | Q28586004 | ||
| Regulation of PTEN transcription by p53 | Q28646911 | ||
| Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines | Q28975767 | ||
| MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer | Q29547523 | ||
| The phosphatidylinositol 3-Kinase AKT pathway in human cancer | Q29547860 | ||
| A role for nuclear PTEN in neuronal differentiation. | Q29568319 | ||
| Fos cooperation with PTEN loss elicits keratoacanthoma not carcinoma, owing to p53/p21 WAF-induced differentiation triggered by GSK3beta inactivation and reduced AKT activity | Q42435449 | ||
| The association between breast carcinoma and meningioma in women | Q42673268 | ||
| PTEN: sometimes taking it off can be better than putting it on. | Q43104730 | ||
| Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN. | Q43621579 | ||
| The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling | Q43848062 | ||
| Promoter methylation and silencing of PTEN in gastric carcinoma | Q43918868 | ||
| Bannayan-Riley-Ruvalcaba syndrome: renaming three formerly recognized syndromes as one etiologic entity | Q44067197 | ||
| Acral papular neuromatosis: an early manifestation of Cowden syndrome. | Q46946076 | ||
| Allelic loss of chromosome 10q23 is associated with tumor progression in breast carcinomas | Q47814647 | ||
| Diffuse cerebellar hypertrophy Lhermitte-Duclos disease | Q48471870 | ||
| Structure and function of phosphoinositide 3-kinases. | Q52532836 | ||
| Insulin-like growth factor-II regulates PTEN expression in the mammary gland. | Q54751832 | ||
| Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma | Q57591227 | ||
| PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies | Q57591287 | ||
| Cerebriform plantar hyperplasia: the major cutaneous feature of Proteus syndrome | Q57720206 | ||
| High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice | Q58378937 | ||
| Multiple Hamartoma Syndrome (Cowden's Disease) | Q69386355 | ||
| Impaired Fas response and autoimmunity in Pten+/- mice | Q73019160 | ||
| Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse | Q73435294 | ||
| A study of the PTEN/MMAC1 gene in 136 breast cancer families | Q74268830 | ||
| PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway | Q74404969 | ||
| Expression and prognostic significance of PTEN product protein in patients with esophageal squamous cell carcinoma | Q77879703 | ||
| Increased nuclear phosphatase and tensin homologue deleted on chromosome 10 is associated with G0-G1 in MCF-7 cells | Q78834996 | ||
| Impaired PI3K/Akt activation-mediated NF-kappaB inactivation under elevated TNF-alpha is more vulnerable to apoptosis in vitiliginous keratinocytes | Q80376781 | ||
| Promoter methylation of the PTEN gene is a common molecular change in breast cancer | Q80403566 | ||
| Reversible inactivation of the tumor suppressor PTEN by H2O2 | Q29615204 | ||
| Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome | Q29615538 | ||
| Cellular senescence: when bad things happen to good cells | Q29615561 | ||
| miR-21-mediated tumor growth | Q29616149 | ||
| The role of phosphoinositide 3-kinase lipid products in cell function | Q33543235 | ||
| PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells | Q33586807 | ||
| Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity | Q33774967 | ||
| PTEN, a unique tumor suppressor gene | Q33974014 | ||
| Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex | Q34101673 | ||
| Cowden syndrome-diagnostic skin signs | Q34309307 | ||
| Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers. | Q34318634 | ||
| Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair. | Q34477787 | ||
| PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome | Q34504165 | ||
| Coordinate regulation of translation by the PI 3-kinase and mTOR pathways | Q34956044 | ||
| Bannayan-Riley-Ruvalcaba syndrome: further delineation of the phenotype and management of PTEN mutation-positive cases. | Q35566202 | ||
| Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH and angiogenesis | Q35641225 | ||
| Epigenetic PTEN silencing in malignant melanomas without PTEN mutation | Q35745799 | ||
| Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells | Q35745875 | ||
| PTEN mutational spectra, expression levels, and subcellular localization in microsatellite stable and unstable colorectal cancers | Q35747653 | ||
| Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors | Q35810225 | ||
| Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression | Q36067596 | ||
| Mucocutaneous neuromas: an underrecognized manifestation of PTEN hamartoma-tumor syndrome | Q36479759 | ||
| Analysis of the 10q23 chromosomal region and the PTEN gene in human sporadic breast carcinoma. | Q36618853 | ||
| Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia | Q37009642 | ||
| Proteus syndrome: 2 case reports and a review of the literature | Q37014418 | ||
| Tenets of PTEN tumor suppression | Q37154214 | ||
| Loss of heterozygosity analysis identifies genetic abnormalities in mycosis fungoides and specific loci associated with disease progression. | Q38430191 | ||
| Mutation and expression analysis of the putative prostate tumour-suppressor gene PTEN | Q39711051 | ||
| Targeting V600EB-Raf and Akt3 using nanoliposomal-small interfering RNA inhibits cutaneous melanocytic lesion development. | Q39899988 | ||
| Transforming growth factor-beta activation promotes genetic context-dependent invasion of immortalized melanocytes | Q39976268 | ||
| CBF-1 (RBP-J kappa) binds to the PTEN promoter and regulates PTEN gene expression | Q40179833 | ||
| Mitogen-activated protein kinase kinase-4 promotes cell survival by decreasing PTEN expression through an NF kappa B-dependent pathway | Q40198440 | ||
| p53 down-regulates phosphatase and tensin homologue deleted on chromosome 10 protein stability partially through caspase-mediated degradation in cells with proteasome dysfunction | Q40267012 | ||
| The proteus syndrome. Partial gigantism of the hands and/or feet, nevi, hemihypertrophy, subcutaneous tumors, macrocephaly or other skull anomalies and possible accelerated growth and visceral affections | Q40273172 | ||
| c-Jun promotes cellular survival by suppression of PTEN. | Q40283457 | ||
| Increased protein expression of the PTEN tumor suppressor in the presence of constitutively active Notch-1. | Q40386132 | ||
| Zinc-induced PTEN protein degradation through the proteasome pathway in human airway epithelial cells. | Q40648400 | ||
| Germline and germline mosaic PTEN mutations associated with a Proteus-like syndrome of hemihypertrophy, lower limb asymmetry, arteriovenous malformations and lipomatosis | Q40770781 | ||
| Form and function in protein dephosphorylation | Q41193500 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 252457 | |
| P577 | publication date | 2012-04-30 | |
| P1433 | published in | The Scientific World Journal | Q7762585 |
| P1476 | title | PTEN gene: a model for genetic diseases in dermatology | |
| P478 | volume | 2012 |
| Q26797287 | Focus on PTEN Regulation |
| Q34353848 | Posttranslational regulation of phosphatase and tensin homolog (PTEN) and its functional impact on cancer behaviors. |
| Q33755023 | Redox Regulation of the Tumor Suppressor PTEN by Hydrogen Peroxide and Tert-Butyl Hydroperoxide |
| Q37691772 | The role of microRNAs in skin fibrosis. |
| Q37472559 | Thyroid involvement in two patients with Bannayan-Riley-Ruvalcaba syndrome. |
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