| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/IJC.10294 |
| P698 | PubMed publication ID | 11948493 |
| P50 | author | Charis Eng | Q37385393 |
| David C. Whiteman | Q37837275 | ||
| P2093 | author name string | Nicholas K Hayward | |
| Margaret C Cummings | |||
| Sandra Pavey | |||
| Xiao-Ping Zhou | |||
| P2860 | cites work | The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation | Q24290417 |
| The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
| PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
| Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers | Q28145813 | ||
| Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN | Q28513537 | ||
| Regulation of PTEN transcription by p53 | Q28646911 | ||
| Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome | Q29615538 | ||
| PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways | Q31837554 | ||
| PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model | Q32069431 | ||
| PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells | Q33586807 | ||
| Variation in cancer risks, by mutation position, in BRCA2 mutation carriers | Q34044197 | ||
| PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome | Q34504165 | ||
| The role of MMAC1 mutations in early-onset breast cancer: causative in association with Cowden syndrome and excluded in BRCA1-negative cases. | Q35250021 | ||
| Identification of PTEN mutations in metastatic melanoma specimens | Q35435625 | ||
| Epigenetic PTEN silencing in malignant melanomas without PTEN mutation | Q35745799 | ||
| Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells | Q35745875 | ||
| Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast | Q35788322 | ||
| Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors | Q35810225 | ||
| Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas | Q35842249 | ||
| Allelic loss of 10q23, the PTEN tumour suppressor gene locus, in Barrett's oesophagus-associated adenocarcinoma | Q36622783 | ||
| Germline and germline mosaic PTEN mutations associated with a Proteus-like syndrome of hemihypertrophy, lower limb asymmetry, arteriovenous malformations and lipomatosis | Q40770781 | ||
| Identification of PTEN/MMAC1 alterations in uncultured melanomas and melanoma cell lines | Q42818580 | ||
| p53 expression and risk factors for cutaneous melanoma: a case-control study. | Q44582665 | ||
| Growth factor and cytogenetic abnormalities in cultured nevi and malignant melanomas | Q44966035 | ||
| Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation | Q45345194 | ||
| Association of germline mutation in the PTEN tumour suppressor gene and Proteus and Proteus-like syndromes | Q57591248 | ||
| PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies | Q57591287 | ||
| Localization of the gene for Cowden disease to chromosome 10q22–23 | Q57694734 | ||
| 10q deletions in metastatic cutaneous melanoma | Q58024973 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cancer research | Q3421914 |
| P1104 | number of pages | 5 | |
| P304 | page(s) | 63-67 | |
| P577 | publication date | 2002-05-01 | |
| P1433 | published in | International Journal of Cancer | Q332492 |
| P1476 | title | Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma | |
| P478 | volume | 99 |
| Q38840793 | A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin transcriptional activity |
| Q34722525 | AMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressor |
| Q35853239 | ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells |
| Q53285916 | Abnormal distribution of hDlg and PTEN in premalignant lesions and invasive cervical cancer. |
| Q34253185 | Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis |
| Q35009571 | Acid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling |
| Q35146577 | Apoptosis and melanoma chemoresistance |
| Q44350476 | BMP2 exposure results in decreased PTEN protein degradation and increased PTEN levels |
| Q35089153 | Biomarkers in melanoma: predisposition, screening and diagnosis |
| Q38330271 | Characterization of nuclear PTEN and its post translational modifications |
| Q36313163 | Class reunion: PTEN joins the nuclear crew. |
| Q30363869 | Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival. |
| Q37593968 | Correlation of NEDD4-1 and PTEN expression with the invasive capacity of pituitary adenomas |
| Q46082313 | Critical role of increased PTEN nuclear translocation in excitotoxic and ischemic neuronal injuries |
| Q33895317 | Different conformations of phosphatase and tensin homolog, deleted on chromosome 10 (PTEN) protein within the nucleus and cytoplasm of neurons |
| Q33649569 | Dormancy of metastatic melanoma |
| Q45700846 | E- to N-cadherin switch in melanoma is associated with decreased expression of phosphatase and tensin homolog and cancer progression |
| Q35914897 | Emerging insights into the molecular and cellular basis of glioblastoma |
| Q37339357 | Expression of Phosphatase and Tensin Homologue, phospho-Akt, and p53 in Acral Benign and Malignant Melanocytic Neoplasms (Benign Nevi, Dysplastic Nevi, and Acral Melanomas) |
| Q91583393 | FBXO22 degrades nuclear PTEN to promote tumorigenesis |
| Q38820110 | From melanocytes to melanomas. |
| Q33744696 | Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc |
| Q37252731 | Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function. |
| Q38980829 | Identification of nucleolus-localized PTEN and its function in regulating ribosome biogenesis |
| Q35798186 | Immunohistochemistry in melanocytic proliferative lesions |
| Q37099496 | In MMTV-Her-2/neu transgenic mammary tumors the absence of caveolin-1-/- alters PTEN and NHERF1 but not β-catenin expression. |
| Q28576729 | Inhibition of neuronal phenotype by PTEN in PC12 cells |
| Q64094161 | MTA2-mediated inhibition of PTEN leads to pancreatic ductal adenocarcinoma carcinogenicity |
| Q35234272 | Macrophage migration inhibitory factor engages PI3K/Akt signalling and is a prognostic factor in metastatic melanoma |
| Q38730348 | Melanocytic nevi and melanoma: unraveling a complex relationship |
| Q28069421 | Melanoma Brain Metastasis: Mechanisms, Models, and Medicine |
| Q40740686 | Molecular pathways: PI3K pathway phosphatases as biomarkers for cancer prognosis and therapy |
| Q92906114 | Multifaceted Regulation of PTEN Subcellular Distributions and Biological Functions |
| Q92207064 | Myosin 1b Regulates Nuclear AKT Activation by Preventing Localization of PTEN in the Nucleus |
| Q38895958 | Ndfip1 represses cell proliferation by controlling Pten localization and signaling specificity |
| Q37304241 | No association between phosphatase and tensin homolog genetic polymorphisms and colon cancer |
| Q42218359 | Nongenomic Mechanisms of PTEN Regulation |
| Q28391204 | Nuclear PTEN levels and G2 progression in melanoma cells |
| Q24337323 | Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner |
| Q42076186 | Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation |
| Q28564702 | Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs |
| Q34707834 | Odontogenic ameloblast-associated protein (ODAM) inhibits growth and migration of human melanoma cells and elicits PTEN elevation and inactivation of PI3K/AKT signaling |
| Q92316075 | PTEN Tumor-Suppressor: The Dam of Stemness in Cancer |
| Q38048884 | PTEN and melanomagenesis |
| Q28217868 | PTEN associates with the vault particles in HeLa cells |
| Q94325481 | PTEN expression in normal skin, acquired melanocytic nevi, and cutaneous melanoma |
| Q51597378 | PTEN gene: a model for genetic diseases in dermatology. |
| Q37977769 | PTEN in DNA damage repair |
| Q24315949 | PTEN inhibits BMI1 function independently of its phosphatase activity |
| Q33663049 | PTEN mediates Notch-dependent stalk cell arrest in angiogenesis |
| Q35747653 | PTEN mutational spectra, expression levels, and subcellular localization in microsatellite stable and unstable colorectal cancers |
| Q57591147 | PTEN mutations are common in sporadic microsatellite stable colorectal cancer |
| Q28505099 | PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression |
| Q26995683 | PTEN plasticity: how the taming of a lethal gene can go too far |
| Q35146572 | PTEN signaling pathways in melanoma |
| Q36360788 | PTEN stabilizes TOP2A and regulates the DNA decatenation |
| Q50977901 | PTEN, Longevity and Age-Related Diseases. |
| Q54579801 | PTEN, pAKT, and pmTOR expression and subcellular distribution in primary renal cell carcinomas and their metastases. |
| Q37955889 | PTEN-Associated Complexes: An Overview. |
| Q37270432 | PTEN: a new guardian of the genome. |
| Q28203387 | PTEN: one gene, many syndromes |
| Q33864068 | Phosphatase and tensin homologue growth suppression without phosphatase |
| Q37059129 | Portrait of PTEN: messages from mutant mice. |
| Q37270440 | Post-translational regulation of PTEN. |
| Q64114534 | Precise definition of PTEN C-terminal epitopes and its implications in clinical oncology |
| Q24613810 | Protean PTEN: form and function |
| Q42109613 | SENP1 regulates PTEN stability to dictate prostate cancer development. |
| Q44504090 | SHIP-2 and PTEN are expressed and active in vascular smooth muscle cell nuclei, but only SHIP-2 is associated with nuclear speckles |
| Q43093016 | Senescence-escape in melanoma |
| Q36042091 | Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors |
| Q35822194 | Targeted agents for the treatment of metastatic melanoma |
| Q39948774 | The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network |
| Q24650856 | The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization |
| Q24292946 | Ubiquitination regulates PTEN nuclear import and tumor suppression |
| Q37034487 | Understanding signaling cascades in melanoma |
| Q33965328 | Using genetics and genomics strategies to personalize therapy for cancer: focus on melanoma |
| Q48140290 | Vanadium pentoxide increased PTEN and decreased SHP1 expression in NK-92MI cells, affecting PI3K-AKT-mTOR and Ras-MAPK pathways. |
| Q33785885 | WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner. |
| Q39067694 | ΔNp63α regulates keratinocyte proliferation by controlling PTEN expression and localization |
| Q37188735 | ΔNp63α represses nuclear translocation of PTEN by inhibition of NEDD4-1 in keratinocytes |
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