scholarly article | Q13442814 |
P2093 | author name string | Hong Wu | |
Bahram Valamehr | |||
Sherly Mosessian | |||
Chun-Ju Chang | |||
David J. Mulholland | |||
William R. Sellers | |||
P2860 | cites work | Threonine phosphorylation of the MMAC1/PTEN PDZ binding domain both inhibits and stimulates PDZ binding | Q22011155 |
Phosphorylation of the PTEN tail regulates protein stability and function | Q22254305 | ||
The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation | Q24290417 | ||
Ubiquitination regulates PTEN nuclear import and tumor suppression | Q24292946 | ||
A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast | Q24336385 | ||
CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis | Q24540387 | ||
Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association | Q27620298 | ||
PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms | Q28181035 | ||
PTEN: one gene, many syndromes | Q28203387 | ||
The biology and clinical relevance of the PTEN tumor suppressor pathway | Q28272157 | ||
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
Essential role for nuclear PTEN in maintaining chromosomal integrity | Q28513781 | ||
Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs | Q28564702 | ||
Live or let die: the cell's response to p53 | Q29547663 | ||
A role for nuclear PTEN in neuronal differentiation. | Q29568319 | ||
The antioxidant function of the p53 tumor suppressor | Q29619231 | ||
PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model | Q32069431 | ||
Diet, androgens, oxidative stress and prostate cancer susceptibility | Q33715166 | ||
Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity | Q33774967 | ||
The multiple roles of PTEN in tumor suppression | Q33849727 | ||
Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex | Q34101673 | ||
Cellular response to oxidative stress: signaling for suicide and survival | Q34138566 | ||
Regulation of PTEN by Rho small GTPases | Q34406790 | ||
The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network | Q34825957 | ||
Human cancer, PTEN and the PI-3 kinase pathway | Q35812408 | ||
Identification of a tumour suppressor network opposing nuclear Akt function | Q35991130 | ||
Cell cycle-dependent nuclear export of phosphatase and tensin homologue tumor suppressor is regulated by the phosphoinositide-3-kinase signaling cascade | Q40050501 | ||
A short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growth | Q40184782 | ||
The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation | Q40254270 | ||
Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta | Q40384036 | ||
PTEN enters the nucleus by diffusion | Q40387100 | ||
Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) has nuclear localization signal-like sequences for nuclear import mediated by major vault protein | Q40421181 | ||
PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy | Q40765673 | ||
Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation | Q42076186 | ||
Changes in endometrial PTEN expression throughout the human menstrual cycle | Q42489118 | ||
PTEN regulates Mdm2 expression through the P1 promoter | Q44848220 | ||
Mechanistic insights into maintenance of high p53 acetylation by PTEN. | Q46035699 | ||
Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma | Q57591227 | ||
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention | Q59067116 | ||
[PTEN tumor suppressor: functions as a lipid phosphatase] | Q73124101 | ||
Increased nuclear phosphatase and tensin homologue deleted on chromosome 10 is associated with G0-G1 in MCF-7 cells | Q78834996 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | oxidative stress | Q898814 |
Transformation related protein 53 | Q14818136 | ||
Phosphatase and tensin homolog | Q14878408 | ||
P304 | page(s) | 3281–3289 | |
P577 | publication date | 2008-05-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression | |
P478 | volume | 28 |
Q28546443 | A functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activity |
Q33374003 | A novel role for the SMG-1 kinase in lifespan and oxidative stress resistance in Caenorhabditis elegans |
Q35853239 | ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells |
Q42496198 | Adaptive basal phosphorylation of eIF2α is responsible for resistance to cellular stress-induced cell death in Pten-null hepatocytes |
Q33740171 | Allele-specific tumor spectrum in pten knockin mice |
Q37431681 | Analysis of PTEN complex assembly and identification of heterogeneous nuclear ribonucleoprotein C as a component of the PTEN-associated complex |
Q36942597 | Analysis of PTEN expression in large intestine polyps and its relation to the recognized histopathological and clinical risk factors for cancer development in this location |
Q37734730 | Anti-diabetic effect of Alpinia oxyphylla extract on 57BL/KsJ db-/db- mice |
Q52578386 | Calcium and Nuclear Signaling in Prostate Cancer. |
Q39080461 | Caveolin-1 in renal cell carcinoma promotes tumour cell invasion, and in co-operation with pERK predicts metastases in patients with clinically confined disease |
Q39365401 | Cell Cycle Control by PTEN. |
Q34079578 | Characterization of a novel PTEN mutation in MDA-MB-453 breast carcinoma cell line |
Q55068347 | Clinical Significance of PTEN Deletion, Mutation, and Loss of PTEN Expression in De Novo Diffuse Large B-Cell Lymphoma. |
Q34481443 | Connection between Tumor Suppressor BRCA1 and PTEN in Damaged DNA Repair |
Q30363869 | Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival. |
Q34673451 | Cowden syndrome-associated germline SDHD variants alter PTEN nuclear translocation through SRC-induced PTEN oxidation |
Q38160495 | Disruption of prostate epithelial differentiation pathways and prostate cancer development |
Q42383055 | Does PTEN gene mutation play any role in Li-Fraumeni syndrome |
Q37400322 | Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas. |
Q64271866 | Effect of PTEN loss on metabolic reprogramming in prostate cancer cells |
Q24622802 | Emerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer development |
Q37708388 | Establishment of a novel cellular model for myxofibrosarcoma heterogeneity |
Q92028215 | Hepatocellular Toxicity of Paris Saponins I, II, VI and VII on Two Kinds of Hepatocytes-HL-7702 and HepaRG Cells, and the Underlying Mechanisms |
Q46835597 | Hypoxic culture conditions enhance the generation of regulatory T cells |
Q38275632 | Identification of intrinsically disordered regions in PTEN and delineation of its function via a network approach |
Q37052883 | Inactivation of specific β cell transcription factors in type 2 diabetes |
Q39297251 | Interference with the PTEN-MAST2 interaction by a viral protein leads to cellular relocalization of PTEN. |
Q28586708 | Involvement of PTEN in TPA-mediated p53-activation in mouse skin epidermal JB6 cells |
Q38266259 | Is Cytoplasmic PTEN a Specific Target for Neuronal Survival? |
Q42203006 | Loss of nuclear PTEN in HCV-infected human hepatocytes |
Q34876968 | MCT-1 expression and PTEN deficiency synergistically promote neoplastic multinucleation through the Src/p190B signaling activation |
Q39093841 | Mahanine synergistically enhances cytotoxicity of 5-fluorouracil through ROS-mediated activation of PTEN and p53/p73 in colon carcinoma |
Q92906114 | Multifaceted Regulation of PTEN Subcellular Distributions and Biological Functions |
Q92207064 | Myosin 1b Regulates Nuclear AKT Activation by Preventing Localization of PTEN in the Nucleus |
Q24316324 | Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response |
Q38206143 | Non-cell autonomous or secretory tumor suppression |
Q42218359 | Nongenomic Mechanisms of PTEN Regulation |
Q39159757 | Nuclear phosphoinositide regulation of chromatin. |
Q33636764 | Nuclear phosphoinositides: a signaling enigma wrapped in a compartmental conundrum. |
Q38733049 | Nuclear transport: a switch for the oxidative stress-signaling circuit? |
Q26862544 | PI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasms |
Q47435142 | PTEN Physically Interacts with and Regulates E2F1-mediated Transcription in Lung Cancer. |
Q92702101 | PTEN as a Prognostic/Predictive Biomarker in Cancer: An Unfulfilled Promise? |
Q30475282 | PTEN attenuates PIP3/Akt signaling in the cochlea of the aging CBA/J mouse |
Q37977769 | PTEN in DNA damage repair |
Q35349562 | PTEN induces apoptosis and cavitation via HIF-2-dependent Bnip3 upregulation during epithelial lumen formation |
Q37606460 | PTEN phosphorylation and nuclear export mediate free fatty acid-induced oxidative stress |
Q24337070 | PTEN suppresses the oncogenic function of AIB1 through decreasing its protein stability via mechanism involving Fbw7 alpha |
Q50977901 | PTEN, Longevity and Age-Related Diseases. |
Q37955889 | PTEN-Associated Complexes: An Overview. |
Q33920955 | PTEN/FOXO3/AKT pathway regulates cell death and mediates morphogenetic differentiation of Colorectal Cancer Cells under Simulated Microgravity. |
Q37270432 | PTEN: a new guardian of the genome. |
Q42921293 | PTENtumor suppressor plays less prognostic role thanP53tumor suppressor in diffuse large B-cell lymphoma |
Q35235757 | Phosphatase and tensin homolog on chromosome 10 is phosphorylated in primary effusion lymphoma and Kaposi's sarcoma |
Q27012953 | Phosphoinositides: tiny lipids with giant impact on cell regulation |
Q35918916 | Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways. |
Q34979078 | Protein interactions of phosphatase and tensin homologue (PTEN) and its cancer-associated G20E mutant compared by using stable isotope labeling by amino acids in cell culture-based parallel affinity purification |
Q33769079 | Repair of oxidative DNA damage, cell-cycle regulation and neuronal death may influence the clinical manifestation of Alzheimer's disease |
Q35064623 | SIRT1 Deficiency Downregulates PTEN/JNK/FOXO1 Pathway to Block Reactive Oxygen Species-Induced Apoptosis in Mouse Embryonic Stem Cells |
Q36638098 | Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression |
Q36995054 | Targeting prostate cancer based on signal transduction and cell cycle pathways. |
Q36137883 | The Optimization of Soluble PTEN Expression in Escherichia coli |
Q30500308 | The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer. |
Q90480486 | The oncogenic role of microRNA-500a in colorectal cancer |
Q37270446 | The role of PTEN signaling perturbations in cancer and in targeted therapy |
Q34540302 | The silencing of Pokemon attenuates the proliferation of hepatocellular carcinoma cells in vitro and in vivo by inhibiting the PI3K/Akt pathway |
Q48362692 | The tumor suppressor PTEN is exported in exosomes and has phosphatase activity in recipient cells |
Q92854358 | Topical MTII Therapy Suppresses Melanoma Through PTEN Upregulation and Cyclooxygenase II Inhibition |
Q38271796 | Understanding the tumor suppressor PTEN in chronic alcoholism and hepatocellular carcinoma |
Q64092698 | Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress |
Search more.